KR101444471B1 - 외과적 절제술 이후에 조직내 남아 있는 미세 잔류 종양을 치료하는 장치 - Google Patents

외과적 절제술 이후에 조직내 남아 있는 미세 잔류 종양을 치료하는 장치 Download PDF

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Publication number
KR101444471B1
KR101444471B1 KR1020087023591A KR20087023591A KR101444471B1 KR 101444471 B1 KR101444471 B1 KR 101444471B1 KR 1020087023591 A KR1020087023591 A KR 1020087023591A KR 20087023591 A KR20087023591 A KR 20087023591A KR 101444471 B1 KR101444471 B1 KR 101444471B1
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South Korea
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tumor
tissue
electroporation
bleomycin
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Expired - Fee Related
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English (en)
Korean (ko)
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KR20090004890A (ko
Inventor
폴 골드파브
디트마 래버스세이
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제네트로닉스, 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Surgical Instruments (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
KR1020087023591A 2006-03-03 2007-03-02 외과적 절제술 이후에 조직내 남아 있는 미세 잔류 종양을 치료하는 장치 Expired - Fee Related KR101444471B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77874006P 2006-03-03 2006-03-03
US60/778,740 2006-03-03
PCT/US2007/005133 WO2007103070A2 (en) 2006-03-03 2007-03-02 Method and device for treating microscopic residual tumors remaining in tissues following surgical resection

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020147014055A Division KR101529448B1 (ko) 2006-03-03 2007-03-02 외과적 절제술 이후에 조직내 남아 있는 미세 잔류 종양을 치료하는 장치

Publications (2)

Publication Number Publication Date
KR20090004890A KR20090004890A (ko) 2009-01-12
KR101444471B1 true KR101444471B1 (ko) 2014-09-24

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KR1020147014055A Active KR101529448B1 (ko) 2006-03-03 2007-03-02 외과적 절제술 이후에 조직내 남아 있는 미세 잔류 종양을 치료하는 장치
KR1020087023591A Expired - Fee Related KR101444471B1 (ko) 2006-03-03 2007-03-02 외과적 절제술 이후에 조직내 남아 있는 미세 잔류 종양을 치료하는 장치

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Country Status (12)

Country Link
US (4) US9037230B2 (enExample)
EP (2) EP1991303B1 (enExample)
JP (3) JP2009528131A (enExample)
KR (2) KR101529448B1 (enExample)
CN (2) CN102921102B (enExample)
AU (1) AU2007224275B2 (enExample)
CA (1) CA2644163C (enExample)
DK (1) DK1991303T3 (enExample)
ES (1) ES2874482T3 (enExample)
NO (2) NO344476B1 (enExample)
PL (1) PL1991303T3 (enExample)
WO (1) WO2007103070A2 (enExample)

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US10238447B2 (en) 2008-04-29 2019-03-26 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
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JP6174632B2 (ja) 2017-08-02
JP2013127000A (ja) 2013-06-27
KR20090004890A (ko) 2009-01-12
US11007365B2 (en) 2021-05-18
KR101529448B1 (ko) 2015-06-18
CN102921102B (zh) 2015-06-10
WO2007103070A2 (en) 2007-09-13
KR20140081894A (ko) 2014-07-01
JP2015213778A (ja) 2015-12-03
EP3845269A1 (en) 2021-07-07
CN102921102A (zh) 2013-02-13
JP2009528131A (ja) 2009-08-06
EP1991303A4 (en) 2012-01-18
ES2874482T3 (es) 2021-11-05
US20210308451A1 (en) 2021-10-07
US12324913B2 (en) 2025-06-10
NO20191102A1 (no) 2008-11-13
EP1991303A2 (en) 2008-11-19
NO344476B1 (no) 2020-01-13
DK1991303T3 (da) 2021-06-07
AU2007224275A1 (en) 2007-09-13
AU2007224275B2 (en) 2012-04-12
CA2644163A1 (en) 2007-09-13
CN101426550B (zh) 2012-10-31
NO20084148L (no) 2008-11-13
PL1991303T3 (pl) 2021-10-11
CA2644163C (en) 2020-05-05
CN101426550A (zh) 2009-05-06
US20170216585A1 (en) 2017-08-03
WO2007103070A3 (en) 2008-08-28
US9037230B2 (en) 2015-05-19
US20070239099A1 (en) 2007-10-11
EP1991303B1 (en) 2021-05-05
US20120143120A1 (en) 2012-06-07

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