KR101425686B1 - 성숙 수지상 세포 조성물 및 그의 배양 방법 - Google Patents
성숙 수지상 세포 조성물 및 그의 배양 방법 Download PDFInfo
- Publication number
- KR101425686B1 KR101425686B1 KR1020087024226A KR20087024226A KR101425686B1 KR 101425686 B1 KR101425686 B1 KR 101425686B1 KR 1020087024226 A KR1020087024226 A KR 1020087024226A KR 20087024226 A KR20087024226 A KR 20087024226A KR 101425686 B1 KR101425686 B1 KR 101425686B1
- Authority
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- South Korea
- Prior art keywords
- cd40l
- cells
- cell
- ifn
- antigen
- Prior art date
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- Expired - Fee Related
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4238—Regulators of development
- A61K40/424—Apoptosis related proteins, e.g. survivin or livin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4244—Enzymes
- A61K40/4246—Telomerase or [telomerase reverse transcriptase [TERT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4271—Melanoma antigens
- A61K40/4272—Melan-A/MART
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/56—Kidney
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/52—CD40, CD40-ligand (CD154)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/400,774 | 2006-04-07 | ||
| US11/400,774 US8513008B2 (en) | 2004-10-07 | 2006-04-07 | Mature dendritic cell compositions and methods for culturing same |
| PCT/US2007/008734 WO2007117682A2 (en) | 2006-04-07 | 2007-04-06 | Mature dendritic cell compositions and methods for culturing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20090006078A KR20090006078A (ko) | 2009-01-14 |
| KR101425686B1 true KR101425686B1 (ko) | 2014-08-01 |
Family
ID=38581685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020087024226A Expired - Fee Related KR101425686B1 (ko) | 2006-04-07 | 2007-04-06 | 성숙 수지상 세포 조성물 및 그의 배양 방법 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US8513008B2 (https=) |
| EP (1) | EP2003969B1 (https=) |
| JP (1) | JP5425618B2 (https=) |
| KR (1) | KR101425686B1 (https=) |
| CN (1) | CN101460054B (https=) |
| AT (1) | ATE510451T1 (https=) |
| AU (1) | AU2007235227B2 (https=) |
| CA (1) | CA2648675C (https=) |
| DK (1) | DK2003969T3 (https=) |
| WO (1) | WO2007117682A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230038350A (ko) * | 2021-09-10 | 2023-03-20 | 이종균 | 수지상 세포, 자연 살해 세포 및 세포 독성 t 세포를 포함하는 암의 예방 또는 치료용 생물학적 조성물 |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8513008B2 (en) * | 2004-10-07 | 2013-08-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
| WO2006042177A2 (en) * | 2004-10-07 | 2006-04-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
| JP5020935B2 (ja) | 2005-04-08 | 2012-09-05 | アルゴス セラピューティクス,インコーポレイティド | 樹状細胞組成物および方法 |
| PL2066339T3 (pl) * | 2006-09-18 | 2015-02-27 | Univ Arkansas | Kompozycje i sposoby zwiększania odpowiedzi immunologicznych |
| US20110086904A1 (en) * | 2007-09-17 | 2011-04-14 | The Trustees Of The University Of Pennsylvania | GENERATION OF HYPERSTABLE mRNAs |
| WO2009059018A1 (en) * | 2007-10-30 | 2009-05-07 | The Board Of Trustees Of The University Of Arkansas | Compositions and methods of enhancing immune responses to flagellated bacterium |
| PT3097926T (pt) | 2007-11-01 | 2020-01-08 | Univ Guelph | Composições e métodos de potenciação das respostas imunitárias frente a eimeria |
| EP2072617A1 (en) * | 2007-12-12 | 2009-06-24 | Trimed Biotech GmbH | Method for producing dendritic cells |
| EP2254998B1 (en) | 2008-02-28 | 2015-12-23 | Argos Therapeutics, Inc. | Transient expression of immunomodulatory polypeptides for the prevention and treatment of autoimmune disease, allergy and transplant rejection |
| ES2643646T3 (es) | 2010-01-21 | 2017-11-23 | The Board Of Trustees Of The University Of Arkansas | Vectores de vacuna y métodos para potenciar las respuestas inmunitarias |
| MX350306B (es) | 2010-06-09 | 2017-09-04 | Univ Arkansas | Vacuna y metodos para reducir una infeccion por campylobacter. |
| EP2621951A1 (en) * | 2010-09-29 | 2013-08-07 | Université de Liège | Combination of an agonistic anti-cd40 monoclonal antibody or a cd40 ligand and inactivated or attenuated bacteria for use in the treatment and/or prevention of mastitis |
| DE13746292T1 (de) * | 2012-02-10 | 2014-10-30 | Hakushinkouseikai Foundation | Proliferationsmittel für monozyten, kulturmedium zur proliferation von monozyten, verfahren zur herstellung von monozyten, verfahren zur herstellung dendritischer zellen und verfahren zur herstellung eines impfstoffs mit dendritischen zellen |
| AR094791A1 (es) | 2013-02-14 | 2015-08-26 | Univ Arkansas | Composiciones y métodos para mejorar las respuestas inmunes ante una infección por eimeria o para limitar una infección por eimeria |
| AU2014239557B2 (en) | 2013-03-15 | 2019-01-03 | The Board Of Trustees Of The University Of Arkansas | Compositions and methods of enhancing immune responses to enteric pathogens |
| WO2015127190A1 (en) * | 2014-02-21 | 2015-08-27 | Argos Therapeutics, Inc. | Tscm cells and methods for use |
| US9730989B2 (en) | 2015-07-02 | 2017-08-15 | PrimeVax Immuno-Oncology, Inc. | Compositions and methods for combination therapy with dengue virus and dendritic cells |
| CA2999881A1 (en) * | 2015-09-26 | 2017-03-30 | PrimeVax Immuno-Oncology, Inc. | Compositions and methods for producing dendritic cells |
| WO2017102010A1 (en) * | 2015-12-17 | 2017-06-22 | Biontech Rna Pharmaceuticals Gmbh | Novel cytokine fusion proteins |
| CN109104870B (zh) * | 2016-01-15 | 2021-10-15 | 丁恩雨 | 一种能够增强mRNA稳定性和可译性的通用核酸药物载体 |
| KR102767638B1 (ko) | 2016-05-03 | 2025-02-20 | 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 | 면역자극 및 항원 폴리펩티드를 포함하는 효모 백신 벡터, 및 그를 이용하는 방법 |
| JP2020500847A (ja) | 2016-11-16 | 2020-01-16 | プライムヴァックス イミュノ−オンコロジー,インク. | 癌の処置のための併用免疫療法 |
| EP3565567A4 (en) | 2017-01-04 | 2020-07-29 | Primevax Immuno-Oncology, Inc. | COMPOSITIONS AND METHODS OF THERAPY WITH DENGUE VIRUS |
| JP2021502419A (ja) | 2017-11-07 | 2021-01-28 | コイミューン インコーポレイテッド | 樹状細胞治療のための方法および使用 |
| CN111166876B (zh) * | 2018-11-13 | 2022-10-11 | 北京启辰生生物科技有限公司 | 一种免疫增强剂组合和编码核酸及其应用 |
| WO2024231621A1 (fr) * | 2023-05-05 | 2024-11-14 | Centre National De La Recherche Scientifique | Acide nucleique synthetique et ses utilisations therapeutiques |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993008207A1 (en) | 1991-10-25 | 1993-04-29 | Immunex Corporation | Novel cytokine |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0411228B1 (en) | 1989-07-31 | 1995-11-08 | International Business Machines Corporation | Controlled fiber-optic switch |
| US5936076A (en) | 1991-08-29 | 1999-08-10 | Kirin Beer Kabushiki Kaisha | αgalactosylceramide derivatives |
| US5962406A (en) * | 1991-10-25 | 1999-10-05 | Immunex Corporation | Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same |
| US5981724A (en) * | 1991-10-25 | 1999-11-09 | Immunex Corporation | DNA encoding CD40 ligand, a cytokine that binds CD40 |
| US7405270B2 (en) | 1991-10-25 | 2008-07-29 | Immunex Corporation | CD40-Ligand lacking native-pattern glycosylation |
| TW261533B (https=) | 1992-07-16 | 1995-11-01 | Kirin Brewery | |
| AU683026B2 (en) | 1992-10-22 | 1997-10-30 | Kirin Pharma Kabushiki Kaisha | Novel shingoglycolipid and use thereof |
| EP0694558B1 (en) | 1993-04-15 | 1999-01-27 | Kirin Beer Kabushiki Kaisha | Novel sphingoglycolipid and use thereof |
| PL181496B1 (pl) * | 1996-03-20 | 2001-07-31 | Politechnika Slaska Im Wincent | Sposób wytwarzania ß-naftolu PL |
| EP0961824A4 (en) | 1996-07-10 | 2003-01-29 | Immunex Corp | METHOD FOR ACTIVATING DENTRITIC CELLS |
| US6017527A (en) * | 1996-07-10 | 2000-01-25 | Immunex Corporation | Activated dendritic cells and methods for their activation |
| TW555562B (en) * | 1996-12-27 | 2003-10-01 | Kirin Brewery | Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof |
| JP3495740B2 (ja) * | 1997-04-10 | 2004-02-09 | 麒麟麦酒株式会社 | α−グリコシルセラミドを含有するNKT細胞活性化剤 |
| TW575420B (en) * | 1997-09-22 | 2004-02-11 | Kirin Brewery | Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides |
| DE69840739D1 (de) | 1997-10-27 | 2009-05-28 | Merix Bioscience Inc | Methode und Zusammensetzung zur Herstellung von reifen dendritischen Zellen |
| DE69940731D1 (de) | 1998-05-26 | 2009-05-28 | Genitrix Llc | Zusammensetzungen und verfahren zur modulation einer immunantwort auf ein antigen durch verabreichung von zytokine-beladenen zellen |
| AU5178800A (en) * | 1999-06-01 | 2000-12-18 | Cornell Research Foundation Inc. | Activation of dendritic cells to enhance immunity |
| US20030077263A1 (en) * | 1999-10-29 | 2003-04-24 | Immunex Corporation | Method of activating dendritic cells |
| US7063845B2 (en) | 2000-04-28 | 2006-06-20 | Gemini Science, Inc. | Human anti-CD40 antibodies |
| US20030059427A1 (en) | 2000-04-28 | 2003-03-27 | Force Walker R. | Isolation and characterization of highly active anti-CD40 antibody |
| JP5184732B2 (ja) * | 2000-06-19 | 2013-04-17 | ベス イスラエル デアコネス メディカル センター | T細胞亜集団に特異的なモノクローナル抗体およびポリクローナル抗体の組成物および使用方法 |
| WO2001098317A2 (en) * | 2000-06-22 | 2001-12-27 | The Brigham And Women's Hospital, Inc. | Alpha-glycosylceramides for treating bacterial and fungal infections |
| DE10041515A1 (de) | 2000-08-24 | 2002-03-14 | Gerold Schuler | Verfahren zur Herstellung gebrauchsfertiger, Antigen-beladener oder -unbeladener, kryokonservierter reifer dendritischer Zellen |
| AU2002232447A1 (en) | 2000-11-02 | 2002-05-15 | Immunex Corporation | Method of enhancing lymphocyte-mediated immune responses |
| US7405076B2 (en) * | 2000-11-14 | 2008-07-29 | Universite Libre De Bruxelles | Generation and use of dendritic cells |
| DE60117167T2 (de) * | 2001-01-15 | 2006-10-05 | I.D.M. Immuno-Designed Molecules | Verfahren zur herstellung von submikropartikel-suspensionen pharmazeutischer substanzen |
| US7767202B2 (en) | 2001-03-16 | 2010-08-03 | The Johns Hopkins University | Modulation of systemic immune responses by transplantation of hematopoietic stem cells transduced with genes encoding antigens and antigen presenting cell regulatory molecules |
| EP1270732A1 (en) | 2001-06-21 | 2003-01-02 | Schuler, Gerold | Improved transfection of eukaryontic cells with linear polynucleotides by electroporation |
| EP1409648A1 (en) * | 2001-07-25 | 2004-04-21 | I.D.M. Immuno-Designed Molecules | New isolated dendritic cells, a process for preparing the same and their use in pharmaceutical compositions |
| EP1434859A2 (en) * | 2001-07-25 | 2004-07-07 | New York University | Use of glycosylceramides as adjuvants for vaccines against infections and cancer |
| EP1437358B1 (en) | 2001-08-16 | 2006-10-18 | Daiichi Asubio Pharma Co., Ltd. | Novel glycolipid and remedial agent for autoimmune disease containing the same as active ingredient |
| EP1444330A1 (en) * | 2001-11-07 | 2004-08-11 | Kirin Beer Kabushiki Kaisha | Expansion of t cells in vitro and expanded t cell populations |
| AU2003251518B2 (en) | 2002-06-13 | 2009-07-02 | New York University | Synthetic C-glycolipid and its use for treating cancer infectious diseases and autoimmune diseases |
| AU2003295331A1 (en) | 2002-09-19 | 2004-04-23 | Centocor, Inc. | Method of inducing maturation of dendritic cells and uses therefor |
| BR0314640A (pt) * | 2002-09-20 | 2005-08-02 | Kirin Brewery | Inibidor de vìrus de hepatite c compreendendo, como um ingrediente ativo, alfa-glicosilceramida |
| US20040146948A1 (en) * | 2002-10-18 | 2004-07-29 | Centenary Institute Of Cancer Medicine And Cell Biology | Compositions and methods for targeting antigen-presenting cells with antibody single-chain variable region fragments |
| AU2003296439B2 (en) * | 2002-12-10 | 2009-05-07 | Argos Therapeutics, Inc. | In situ maturation of dendritic cells |
| SE0301109D0 (sv) | 2003-04-14 | 2003-04-14 | Mallen Huang | Nucleotide vaccine composition |
| US20050003533A1 (en) * | 2003-05-08 | 2005-01-06 | Pawel Kalinski | Mature type-1 polarized dendritic cells with enhanced IL-12 production and methods of serum-free production and use |
| EP1648555B1 (en) | 2003-07-18 | 2015-09-02 | Eastern Virginia Medical School | Method for introducing an Agent into a Cell |
| CA2546378A1 (en) | 2003-11-25 | 2005-06-09 | Argos Therapeutics, Inc. | Mrna transfected antigen presenting cells |
| CA2560969A1 (en) * | 2004-03-31 | 2005-11-03 | New York University | Novel synthetic c-glycolipids, their synthesis and use to treat infections, cancer and autoimmune diseases |
| US8513008B2 (en) | 2004-10-07 | 2013-08-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
| WO2006042177A2 (en) * | 2004-10-07 | 2006-04-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
| JP5020935B2 (ja) * | 2005-04-08 | 2012-09-05 | アルゴス セラピューティクス,インコーポレイティド | 樹状細胞組成物および方法 |
-
2006
- 2006-04-07 US US11/400,774 patent/US8513008B2/en not_active Expired - Fee Related
-
2007
- 2007-04-06 DK DK07755113.3T patent/DK2003969T3/da active
- 2007-04-06 JP JP2009504346A patent/JP5425618B2/ja not_active Expired - Fee Related
- 2007-04-06 AU AU2007235227A patent/AU2007235227B2/en not_active Ceased
- 2007-04-06 EP EP07755113A patent/EP2003969B1/en active Active
- 2007-04-06 CA CA2648675A patent/CA2648675C/en active Active
- 2007-04-06 AT AT07755113T patent/ATE510451T1/de active
- 2007-04-06 US US12/226,092 patent/US20120269832A1/en not_active Abandoned
- 2007-04-06 CN CN200780020901.5A patent/CN101460054B/zh not_active Expired - Fee Related
- 2007-04-06 WO PCT/US2007/008734 patent/WO2007117682A2/en not_active Ceased
- 2007-04-06 KR KR1020087024226A patent/KR101425686B1/ko not_active Expired - Fee Related
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2013
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993008207A1 (en) | 1991-10-25 | 1993-04-29 | Immunex Corporation | Novel cytokine |
Non-Patent Citations (1)
| Title |
|---|
| Int Immunol. 2002 Apr;14(4):367-80. * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230038350A (ko) * | 2021-09-10 | 2023-03-20 | 이종균 | 수지상 세포, 자연 살해 세포 및 세포 독성 t 세포를 포함하는 암의 예방 또는 치료용 생물학적 조성물 |
| KR102698871B1 (ko) * | 2021-09-10 | 2024-08-28 | 이종균 | 수지상 세포, 자연 살해 세포 및 세포 독성 t 세포를 포함하는 암의 예방 또는 치료용 생물학적 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2648675A1 (en) | 2007-10-18 |
| EP2003969A2 (en) | 2008-12-24 |
| KR20090006078A (ko) | 2009-01-14 |
| CN101460054B (zh) | 2014-03-12 |
| US20070082400A1 (en) | 2007-04-12 |
| CA2648675C (en) | 2015-03-10 |
| WO2007117682A2 (en) | 2007-10-18 |
| US9523077B2 (en) | 2016-12-20 |
| EP2003969B1 (en) | 2011-05-25 |
| DK2003969T3 (da) | 2011-09-12 |
| ATE510451T1 (de) | 2011-06-15 |
| US20140017788A1 (en) | 2014-01-16 |
| JP5425618B2 (ja) | 2014-02-26 |
| US20120269832A1 (en) | 2012-10-25 |
| WO2007117682A3 (en) | 2008-10-16 |
| US20170096639A1 (en) | 2017-04-06 |
| US8513008B2 (en) | 2013-08-20 |
| EP2003969A4 (en) | 2009-05-13 |
| JP2009533025A (ja) | 2009-09-17 |
| AU2007235227B2 (en) | 2012-10-04 |
| CN101460054A (zh) | 2009-06-17 |
| AU2007235227A1 (en) | 2007-10-18 |
| US10184108B2 (en) | 2019-01-22 |
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