KR101388391B1 - 에스터라제 활성을 갖는 폴리펩티드 및 재조합 에스터라제및 그의 용도 - Google Patents

에스터라제 활성을 갖는 폴리펩티드 및 재조합 에스터라제및 그의 용도 Download PDF

Info

Publication number
KR101388391B1
KR101388391B1 KR1020087018341A KR20087018341A KR101388391B1 KR 101388391 B1 KR101388391 B1 KR 101388391B1 KR 1020087018341 A KR1020087018341 A KR 1020087018341A KR 20087018341 A KR20087018341 A KR 20087018341A KR 101388391 B1 KR101388391 B1 KR 101388391B1
Authority
KR
South Korea
Prior art keywords
alkyl
formula
halopent
leu
esterase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020087018341A
Other languages
English (en)
Korean (ko)
Other versions
KR20080093109A (ko
Inventor
게르하르드 스테인바우어
마이클 스태네크
피터 포자리에브
볼프강 스크랭크
헬무트 슈밥
마르셀 부볼쯔
요아네스 키어켈스
헤랄드 피칠러
마누엘라 헤르만
크리스토프 젠즈메이어
Original Assignee
데에스엠 피네 케미칼스 오스트리아 엔에프게 게엠베하 운트 코 카게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 데에스엠 피네 케미칼스 오스트리아 엔에프게 게엠베하 운트 코 카게 filed Critical 데에스엠 피네 케미칼스 오스트리아 엔에프게 게엠베하 운트 코 카게
Publication of KR20080093109A publication Critical patent/KR20080093109A/ko
Application granted granted Critical
Publication of KR101388391B1 publication Critical patent/KR101388391B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020087018341A 2005-12-27 2006-12-08 에스터라제 활성을 갖는 폴리펩티드 및 재조합 에스터라제및 그의 용도 Expired - Fee Related KR101388391B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ATA2081/2005 2005-12-27
AT0208105A AT502990A1 (de) 2005-12-27 2005-12-27 Neues polypeptid mit esteraseaktivität, und rekombinante esterase sowie deren verwendung
PCT/EP2006/011832 WO2007073845A2 (en) 2005-12-27 2006-12-08 Polypeptide having esterase activity and recombinant esterase and use thereof

Publications (2)

Publication Number Publication Date
KR20080093109A KR20080093109A (ko) 2008-10-20
KR101388391B1 true KR101388391B1 (ko) 2014-04-22

Family

ID=38017096

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020087018341A Expired - Fee Related KR101388391B1 (ko) 2005-12-27 2006-12-08 에스터라제 활성을 갖는 폴리펩티드 및 재조합 에스터라제및 그의 용도

Country Status (14)

Country Link
US (2) US8158393B2 (https=)
EP (1) EP1966373B1 (https=)
JP (1) JP5119166B2 (https=)
KR (1) KR101388391B1 (https=)
CN (1) CN101351548B (https=)
AT (2) AT502990A1 (https=)
BR (1) BRPI0621280A8 (https=)
CA (1) CA2635380C (https=)
ES (1) ES2383702T3 (https=)
IL (1) IL192400A (https=)
NO (1) NO343225B1 (https=)
PL (1) PL1966373T3 (https=)
SG (1) SG170757A1 (https=)
WO (1) WO2007073845A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2171061B1 (en) * 2007-07-04 2017-09-27 DPx Holdings B.V. Preparation of an esterase
DK2421962T3 (en) 2009-04-24 2018-10-22 Dpx Holdings Bv Novagraaf Brevets, Batiment 02, 2 rue Sarah Bernhardt CS90017, F-92665 Asniéres-surSeine cedex, France

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004055177A2 (en) 2002-12-13 2004-07-01 Degussa Ag Artificial esterases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817490A (en) * 1996-05-17 1998-10-06 Eastman Chemical Company Enzymatic process for the manufacture of ascorbic acid 2-keto-L-gulonic acid and esters of 2-keto-L-gulonic acid
DE10061864A1 (de) 2000-12-12 2002-07-11 Aventis Res & Tech Gmbh & Co Rekombinante Schweineleberesterase, deren Verwendung sowie ein Verfahren zu deren Herstellung

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004055177A2 (en) 2002-12-13 2004-07-01 Degussa Ag Artificial esterases

Also Published As

Publication number Publication date
PL1966373T3 (pl) 2012-08-31
US20100151541A1 (en) 2010-06-17
EP1966373A2 (en) 2008-09-10
ATE549400T1 (de) 2012-03-15
ES2383702T3 (es) 2012-06-25
CA2635380C (en) 2014-10-21
AT502990A1 (de) 2007-07-15
CA2635380A1 (en) 2007-07-05
JP2009521239A (ja) 2009-06-04
HK1128306A1 (en) 2009-10-23
NO20082864L (no) 2008-09-25
WO2007073845A8 (en) 2008-07-24
CN101351548A (zh) 2009-01-21
IL192400A (en) 2013-06-27
BRPI0621280A8 (pt) 2017-09-19
EP1966373B1 (en) 2012-03-14
IL192400A0 (en) 2009-02-11
CN101351548B (zh) 2015-08-19
JP5119166B2 (ja) 2013-01-16
WO2007073845A2 (en) 2007-07-05
KR20080093109A (ko) 2008-10-20
WO2007073845A3 (en) 2007-08-02
US20120220014A1 (en) 2012-08-30
NO343225B1 (no) 2018-12-10
US8642312B2 (en) 2014-02-04
US8158393B2 (en) 2012-04-17
BRPI0621280A2 (pt) 2011-12-06
SG170757A1 (en) 2011-05-30

Similar Documents

Publication Publication Date Title
Lange et al. Cloning, functional expression, and characterization of recombinant pig liver esterase
AU2003221082B2 (en) Novel carbonyl reductase, gene encoding it and process for producing optically active alcohols using the same
KR101388391B1 (ko) 에스터라제 활성을 갖는 폴리펩티드 및 재조합 에스터라제및 그의 용도
JP4263482B2 (ja) 組み換えブタ肝臓エステラーゼ、その使用及びその製造方法
KR102227399B1 (ko) 내열성 신규 포스포리파아제 a2 및 포스포리파아제 a2 생산방법
JP5453238B2 (ja) ブタ肝臓エステラーゼのイソ型
AU2001284047B2 (en) Butinol I esterase
WO2007073847A1 (en) Novel polypeptide having esterase activity and recombinant esterase and use thereof
JP2009521239A5 (https=)
AT502992B1 (de) Verfahren zur herstellung von enantiomerenangereicherten 2-alkyl-5-halogen-pent-4-en-carbonsäuren bzw. -carbonsäureestern
HK1128306B (en) Polypeptide having esterase activity and ecombinant esterase and use thereof
KR102884132B1 (ko) sn-1과 sn-3에 대한 균등한 입체선택성을 보이는 라이페이스
US7323325B2 (en) Shrimp alkaline phosphatase
KR20050119151A (ko) 판토락톤 하이드롤라제

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

AMND Amendment
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

A201 Request for examination
AMND Amendment
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

AMND Amendment
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E601 Decision to refuse application
PE0601 Decision on rejection of patent

St.27 status event code: N-2-6-B10-B15-exm-PE0601

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

St.27 status event code: A-3-3-V10-V11-apl-PJ0201

AMND Amendment
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PB0901 Examination by re-examination before a trial

St.27 status event code: A-6-3-E10-E12-rex-PB0901

B701 Decision to grant
PB0701 Decision of registration after re-examination before a trial

St.27 status event code: A-3-4-F10-F13-rex-PB0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

FPAY Annual fee payment

Payment date: 20170317

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20220417

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20220417