KR101387835B1 - 코팅된 제약 제형을 제조하기 위한 중합체 혼합물의 용도및 혼합된 중합체성 코팅을 갖는 제약 제형 - Google Patents

코팅된 제약 제형을 제조하기 위한 중합체 혼합물의 용도및 혼합된 중합체성 코팅을 갖는 제약 제형 Download PDF

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Publication number
KR101387835B1
KR101387835B1 KR1020077027199A KR20077027199A KR101387835B1 KR 101387835 B1 KR101387835 B1 KR 101387835B1 KR 1020077027199 A KR1020077027199 A KR 1020077027199A KR 20077027199 A KR20077027199 A KR 20077027199A KR 101387835 B1 KR101387835 B1 KR 101387835B1
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KR
South Korea
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weight
polymer
active ingredient
copolymer
acrylate
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Expired - Fee Related
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KR1020077027199A
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English (en)
Korean (ko)
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KR20080009213A (ko
Inventor
크리스티안 마이어
카린 크누펜
한스-울리히 페테라이트
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에보니크 룀 게엠베하
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Application granted granted Critical
Publication of KR101387835B1 publication Critical patent/KR101387835B1/ko
Assigned to 에보니크 오퍼레이션즈 게엠베하 reassignment 에보니크 오퍼레이션즈 게엠베하 권리의 전부이전등록 Assignors: 룀 게엠베하
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
KR1020077027199A 2005-05-25 2006-03-03 코팅된 제약 제형을 제조하기 위한 중합체 혼합물의 용도및 혼합된 중합체성 코팅을 갖는 제약 제형 Expired - Fee Related KR101387835B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005024614A DE102005024614A1 (de) 2005-05-25 2005-05-25 Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug
DE102005024614.1 2005-05-25
PCT/EP2006/001949 WO2006125483A1 (de) 2005-05-25 2006-03-03 Verwendung vom polymermischungen zur herstellung von überzogenen arzneiformen sowie arzneiform mit

Publications (2)

Publication Number Publication Date
KR20080009213A KR20080009213A (ko) 2008-01-25
KR101387835B1 true KR101387835B1 (ko) 2014-04-25

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KR1020077027199A Expired - Fee Related KR101387835B1 (ko) 2005-05-25 2006-03-03 코팅된 제약 제형을 제조하기 위한 중합체 혼합물의 용도및 혼합된 중합체성 코팅을 갖는 제약 제형

Country Status (15)

Country Link
US (1) US20080193522A1 (https=)
EP (1) EP1890682B1 (https=)
JP (1) JP5582701B2 (https=)
KR (1) KR101387835B1 (https=)
CN (1) CN101137354B (https=)
BR (1) BRPI0610206B8 (https=)
CA (1) CA2606587C (https=)
DE (1) DE102005024614A1 (https=)
ES (1) ES2628962T3 (https=)
HU (1) HUE032869T2 (https=)
IL (1) IL187535A0 (https=)
MX (1) MX363064B (https=)
PL (1) PL1890682T3 (https=)
SI (1) SI1890682T1 (https=)
WO (1) WO2006125483A1 (https=)

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PL2187876T3 (pl) * 2007-09-21 2013-01-31 Evonik Roehm Gmbh Farmaceutyczna kompozycja opioidowa o zależnym od pH kontrolowanym uwalnianiu z odpornością przed wpływem etanolu
PL2187875T3 (pl) 2007-09-21 2013-01-31 Evonik Roehm Gmbh Kompozycja farmaceutyczna o zależnym od pH kontrolowanym uwalnianiu dla nieopioidów z odpornością przed wpływem etanolu
WO2009049160A1 (en) * 2007-10-12 2009-04-16 Takeda Pharmaceuticals North America Methods of treating gastrointestinal disorders independent of the intake of food
TWI441658B (zh) * 2008-03-11 2014-06-21 Takeda Pharmaceutical 口腔崩解固體製劑
CN102119027A (zh) * 2008-06-26 2011-07-06 麦克内尔-Ppc股份有限公司 含有药物活性剂的包衣颗粒
WO2010034342A1 (en) * 2008-09-24 2010-04-01 Evonik Röhm Gmbh Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol
CA2738197C (en) 2008-09-24 2016-01-05 Evonik Operations Gmbh Ph-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
CN104984343B (zh) * 2008-09-24 2019-04-02 赢创罗姆有限公司 耐受乙醇影响的非阿片类药物的pH依赖性受控释放的药物组合物
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CN105287434A (zh) * 2009-03-18 2016-02-03 赢创罗姆有限公司 采用含有中性乙烯基聚合物和赋形剂的包衣的具有耐乙醇影响的控释药物组合物
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US20100303920A1 (en) * 2009-05-27 2010-12-02 Johan Hjartstam Aqueous Film Coating Composition / 841
US8329208B2 (en) 2009-07-28 2012-12-11 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
EP2490675B1 (en) * 2009-10-22 2019-01-23 Synthon B.V. Pharmaceutical compositions of sevelamer
BR112013027484A8 (pt) * 2011-06-17 2022-07-05 Evonik Roehm Gmbh Composição farmacêutica ou nutracêutica com resistência gástrica, e uso de um polímero de (met)acrilato
JP5877935B2 (ja) 2012-10-17 2016-03-08 メチレーション・サイエンシーズ・インターナショナル・ソサイアティーズ・ウィズ・リストリクティッド・ライアビリティＭｅｔｈｙｌａｔｉｏｎ Ｓｃｉｅｎｃｅｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｓｒｌ Ｓ−アデノシルメチオニンおよび没食子酸エステルを含む組成物
CA2936740C (en) 2014-10-31 2017-10-10 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
JP6824197B2 (ja) 2015-06-05 2021-02-03 エボニック オペレーションズ ゲーエムベーハー エタノールの影響に対する耐性を有する医薬品組成物または栄養機能食品組成物
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
JP6739275B2 (ja) * 2016-08-02 2020-08-12 日本化薬株式会社 ゲフィチニブを有効成分とする医薬組成物
IT201700032367A1 (it) * 2017-03-23 2018-09-23 Lamberti Spa Dispersioni poliuretaniche acquose
JP2021515778A (ja) * 2018-03-09 2021-06-24 エボニック オペレーションズ ゲーエムベーハー エタノールの影響に対する耐性を有するポリマー混合物
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
EP3981849A4 (en) 2019-06-07 2023-06-07 Nippon Soda Co., Ltd. WET COATING AGENT FOR FINE PARTICLES
US20220257517A1 (en) * 2019-06-13 2022-08-18 Evonik Operations Gmbh Powder composition comprising a copolymer mixture and a water-soluble cellulose
US12569481B2 (en) 2020-06-12 2026-03-10 Vanderbilt University Methods of treatment for gastrointestinal motility disorders
CN111700871A (zh) * 2020-06-24 2020-09-25 杭州巴洛特生物科技有限公司 一种美沙拉嗪组合物及其制备方法
CN112237572A (zh) * 2020-10-28 2021-01-19 海南卫康制药(潜山)有限公司 一种富马酸沃诺拉赞片剂及其制备方法
CN114409998A (zh) * 2021-12-24 2022-04-29 浙江普利特新材料有限公司 一种蜂窝状咖啡炭复合隔音降噪聚丙烯材料及其制备方法
WO2024238657A2 (en) 2023-05-15 2024-11-21 Bonafide Health, Llc Sleep-improving compositions and methods of use
CN120204161A (zh) * 2025-04-08 2025-06-27 江西英特科胜动保科技有限公司 一种氟尼辛葡甲胺颗粒及其制备方法

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Also Published As

Publication number Publication date
MX363064B (es) 2019-03-06
ES2628962T3 (es) 2017-08-04
SI1890682T1 (sl) 2017-10-30
MX2007014024A (es) 2008-04-09
CA2606587C (en) 2015-05-26
EP1890682B1 (de) 2017-05-03
CN101137354B (zh) 2014-06-11
EP1890682A1 (de) 2008-02-27
BRPI0610206A2 (pt) 2010-06-01
CA2606587A1 (en) 2006-11-30
WO2006125483A1 (de) 2006-11-30
HK1116341A1 (en) 2008-12-19
CN101137354A (zh) 2008-03-05
BRPI0610206B8 (pt) 2022-07-05
IL187535A0 (en) 2008-03-20
JP5582701B2 (ja) 2014-09-03
BRPI0610206B1 (pt) 2020-10-06
JP2008542211A (ja) 2008-11-27
HUE032869T2 (en) 2017-11-28
DE102005024614A1 (de) 2006-11-30
KR20080009213A (ko) 2008-01-25
PL1890682T3 (pl) 2017-10-31
US20080193522A1 (en) 2008-08-14

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