DE102005024614A1 - Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug - Google Patents

Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug Download PDF

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Publication number
DE102005024614A1
DE102005024614A1 DE102005024614A DE102005024614A DE102005024614A1 DE 102005024614 A1 DE102005024614 A1 DE 102005024614A1 DE 102005024614 A DE102005024614 A DE 102005024614A DE 102005024614 A DE102005024614 A DE 102005024614A DE 102005024614 A1 DE102005024614 A1 DE 102005024614A1
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DE
Germany
Prior art keywords
polymer
weight
copolymer
polymers
acrylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102005024614A
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German (de)
English (en)
Inventor
Christian Dr. Meier
Karin Knuppen
Hans-Ulrich Petereit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roehm GmbH Darmstadt
Original Assignee
Roehm GmbH Darmstadt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roehm GmbH Darmstadt filed Critical Roehm GmbH Darmstadt
Priority to DE102005024614A priority Critical patent/DE102005024614A1/de
Priority to HK08106684.0A priority patent/HK1116341B/xx
Priority to US11/909,315 priority patent/US20080193522A1/en
Priority to BRPI0610206A priority patent/BRPI0610206B8/pt
Priority to CN200680007508.8A priority patent/CN101137354B/zh
Priority to HUE06723193A priority patent/HUE032869T2/en
Priority to JP2008512703A priority patent/JP5582701B2/ja
Priority to PL06723193T priority patent/PL1890682T3/pl
Priority to MX2007014024A priority patent/MX363064B/es
Priority to PCT/EP2006/001949 priority patent/WO2006125483A1/de
Priority to EP06723193.6A priority patent/EP1890682B1/de
Priority to KR1020077027199A priority patent/KR101387835B1/ko
Priority to SI200632186T priority patent/SI1890682T1/sl
Priority to ES06723193.6T priority patent/ES2628962T3/es
Priority to CA2606587A priority patent/CA2606587C/en
Publication of DE102005024614A1 publication Critical patent/DE102005024614A1/de
Priority to IL187535A priority patent/IL187535A0/en
Withdrawn legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
DE102005024614A 2005-05-25 2005-05-25 Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug Withdrawn DE102005024614A1 (de)

Priority Applications (16)

Application Number Priority Date Filing Date Title
DE102005024614A DE102005024614A1 (de) 2005-05-25 2005-05-25 Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug
PL06723193T PL1890682T3 (pl) 2005-05-25 2006-03-03 Zastosowanie mieszanin polimerów do wytwarzania powlekanych postaci leków oraz postaci leku z mieszaną powłoką polimerową
EP06723193.6A EP1890682B1 (de) 2005-05-25 2006-03-03 Verwendung vom polymermischungen zur herstellung von überzogenen arzneiformen sowie arzneiform mit
BRPI0610206A BRPI0610206B8 (pt) 2005-05-25 2006-03-03 uso de misturas de polímeros para a produção de formulações farmacêuticas revestidas, e formulação farmacêutica com revestimento polimérico misto
CN200680007508.8A CN101137354B (zh) 2005-05-25 2006-03-03 聚合物混合物在生产经包衣的药物制剂中的应用和具有混合聚合物包衣的药物制剂
HUE06723193A HUE032869T2 (en) 2005-05-25 2006-03-03 The use of polymer blends for the production of coated pharmaceutical forms, as well as pharmaceutical forms containing a mixed polymer coating
JP2008512703A JP5582701B2 (ja) 2005-05-25 2006-03-03 被覆医薬製剤およびポリマー混合被覆した医薬製剤の製造のためのポリマー混合物の使用
HK08106684.0A HK1116341B (en) 2005-05-25 2006-03-03 Use of polymer mixtures for the production of coated pharmaceutical formulations and pharmaceutical formulation with mixed polymeric coating
MX2007014024A MX363064B (es) 2005-05-25 2006-03-03 Uso de mezclas polimericas para la produccion de formulaciones farmaceuticas recubiertas y formulacion farmaceutica con recubrimiento polimerico mezclado.
PCT/EP2006/001949 WO2006125483A1 (de) 2005-05-25 2006-03-03 Verwendung vom polymermischungen zur herstellung von überzogenen arzneiformen sowie arzneiform mit
US11/909,315 US20080193522A1 (en) 2005-05-25 2006-03-03 Use of Polymer Mixtures For the Production of Coated Pharmaceutical Formulations and Pharmaceutical Formulation With Mixed Polymeric Coating
KR1020077027199A KR101387835B1 (ko) 2005-05-25 2006-03-03 코팅된 제약 제형을 제조하기 위한 중합체 혼합물의 용도및 혼합된 중합체성 코팅을 갖는 제약 제형
SI200632186T SI1890682T1 (sl) 2005-05-25 2006-03-03 Uporaba polimernih mešanic za izdelavo oplaščenih farmacevtski formulacij in farmacevtske formulacije z mešanim polimernim oplaščenjem
ES06723193.6T ES2628962T3 (es) 2005-05-25 2006-03-03 Empleo de mezclas de polímeros para la producción de formas farmacéuticas revestidas, así como forma farmacéutica con revestimiento mixto polímero
CA2606587A CA2606587C (en) 2005-05-25 2006-03-03 The use of polymer mixtures for the production of coated pharmaceutical formulations and pharmaceutical formulation with mixed polymeric coating
IL187535A IL187535A0 (en) 2005-05-25 2007-11-21 Use of polymer mixtures for the production of coated pharmaceutical formulations and pharmaceutical formulation with mixed polymeric coating

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005024614A DE102005024614A1 (de) 2005-05-25 2005-05-25 Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug

Publications (1)

Publication Number Publication Date
DE102005024614A1 true DE102005024614A1 (de) 2006-11-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE102005024614A Withdrawn DE102005024614A1 (de) 2005-05-25 2005-05-25 Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug

Country Status (15)

Country Link
US (1) US20080193522A1 (https=)
EP (1) EP1890682B1 (https=)
JP (1) JP5582701B2 (https=)
KR (1) KR101387835B1 (https=)
CN (1) CN101137354B (https=)
BR (1) BRPI0610206B8 (https=)
CA (1) CA2606587C (https=)
DE (1) DE102005024614A1 (https=)
ES (1) ES2628962T3 (https=)
HU (1) HUE032869T2 (https=)
IL (1) IL187535A0 (https=)
MX (1) MX363064B (https=)
PL (1) PL1890682T3 (https=)
SI (1) SI1890682T1 (https=)
WO (1) WO2006125483A1 (https=)

Cited By (7)

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EP2124552A4 (en) * 2007-01-31 2013-01-09 Methylation Sciences Internat Srl PHARMACEUTICAL FORMULATIONS WITH PROLONGED RELEASE OF S-ADENOSYLMETHIONINE
US8580296B2 (en) 2009-07-28 2013-11-12 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
EP2490675B1 (en) * 2009-10-22 2019-01-23 Synthon B.V. Pharmaceutical compositions of sevelamer
WO2019170485A1 (en) 2018-03-09 2019-09-12 Evonik Röhm Gmbh Polymer mixture with resistance against the influence of ethanol
WO2020249505A1 (en) * 2019-06-13 2020-12-17 Evonik Operations Gmbh Powder composition comprising a copolymer mixture and a water-soluble cellulose
US12239623B2 (en) 2023-05-15 2025-03-04 Bonafide Health, Llc Sleep-improving compositions and methods of use
US12303524B2 (en) 2012-10-17 2025-05-20 Msi-195 Holdings, Llc Compositions comprising S-adenosylmethionine and a gallic acid ester

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WO2008070072A2 (en) * 2006-12-01 2008-06-12 Mutual Pharmaceutical Company, Inc. Carvedilol forms, compositions, and methods of preparation thereof
CN101801357B (zh) * 2007-09-21 2013-08-07 赢创罗姆有限公司 耐受乙醇的影响的pH依赖性受控释放的药物组合物
SI2187875T1 (sl) * 2007-09-21 2012-12-31 Evonik Rohm Gmbh Od pH odvisen farmacevtski sestavek z nadzorovanim sproščanjem za ne-opioide z odpornostjo na vpliv etanola
SG185296A1 (en) * 2007-10-12 2012-11-29 Takeda Pharmaceuticals Usa Inc Methods of treating gastrointestinal disorders independent of the intake of food
TWI441658B (zh) * 2008-03-11 2014-06-21 Takeda Pharmaceutical 口腔崩解固體製劑
RU2011102777A (ru) * 2008-06-26 2012-08-10 МакНЕЙЛ-ППС, ИНК. (US) Частицы с покрытием, содержащие фармацевтически активные агенты
CN104984343B (zh) * 2008-09-24 2019-04-02 赢创罗姆有限公司 耐受乙醇影响的非阿片类药物的pH依赖性受控释放的药物组合物
JP5453434B2 (ja) * 2008-09-24 2014-03-26 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング エタノールの影響に対する耐性を有するオピオイドではないpH依存の制御放出の医薬組成物
MX2011003047A (es) * 2008-09-24 2011-04-14 Evonik Roehm Gmbh Composicion farmaceutica de opioide de liberacion controlada ph dependiente con resistencia contra la influencia de etanol.
WO2010077669A2 (en) * 2008-12-08 2010-07-08 Teva Pharmaceutical Industries Ltd. Palonosetron formulation
CN102365083A (zh) * 2009-03-18 2012-02-29 赢创罗姆有限公司 采用包含聚合物混合物和赋形剂的包衣的具有耐乙醇影响的控释药物组合物
CN105287434A (zh) * 2009-03-18 2016-02-03 赢创罗姆有限公司 采用含有中性乙烯基聚合物和赋形剂的包衣的具有耐乙醇影响的控释药物组合物
SI2408436T1 (sl) * 2009-03-18 2017-06-30 Evonik Roehm Gmbh Farmacevtski sestavek z nadzorovanim sproščanjem z odpornostjo na vpliv etanola, ki uporablja oplaščenje, ki vsebuje nevtralne vinil polimere in ekscipiente
US20100303920A1 (en) * 2009-05-27 2010-12-02 Johan Hjartstam Aqueous Film Coating Composition / 841
BR112013027484A8 (pt) * 2011-06-17 2022-07-05 Evonik Roehm Gmbh Composição farmacêutica ou nutracêutica com resistência gástrica, e uso de um polímero de (met)acrilato
CA2902911C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
JP6824197B2 (ja) 2015-06-05 2021-02-03 エボニック オペレーションズ ゲーエムベーハー エタノールの影響に対する耐性を有する医薬品組成物または栄養機能食品組成物
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
JP6739275B2 (ja) * 2016-08-02 2020-08-12 日本化薬株式会社 ゲフィチニブを有効成分とする医薬組成物
IT201700032367A1 (it) * 2017-03-23 2018-09-23 Lamberti Spa Dispersioni poliuretaniche acquose
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
CN114026188A (zh) * 2019-06-07 2022-02-08 日本曹达株式会社 微粒用的湿式涂布剂
US12569481B2 (en) 2020-06-12 2026-03-10 Vanderbilt University Methods of treatment for gastrointestinal motility disorders
CN111700871A (zh) * 2020-06-24 2020-09-25 杭州巴洛特生物科技有限公司 一种美沙拉嗪组合物及其制备方法
CN112237572A (zh) * 2020-10-28 2021-01-19 海南卫康制药(潜山)有限公司 一种富马酸沃诺拉赞片剂及其制备方法
CN114409998A (zh) * 2021-12-24 2022-04-29 浙江普利特新材料有限公司 一种蜂窝状咖啡炭复合隔音降噪聚丙烯材料及其制备方法
CN120204161A (zh) * 2025-04-08 2025-06-27 江西英特科胜动保科技有限公司 一种氟尼辛葡甲胺颗粒及其制备方法

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2124552A4 (en) * 2007-01-31 2013-01-09 Methylation Sciences Internat Srl PHARMACEUTICAL FORMULATIONS WITH PROLONGED RELEASE OF S-ADENOSYLMETHIONINE
US8580296B2 (en) 2009-07-28 2013-11-12 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
US8865203B2 (en) 2009-07-28 2014-10-21 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
US9931356B2 (en) 2009-07-28 2018-04-03 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
EP2490675B1 (en) * 2009-10-22 2019-01-23 Synthon B.V. Pharmaceutical compositions of sevelamer
US12303524B2 (en) 2012-10-17 2025-05-20 Msi-195 Holdings, Llc Compositions comprising S-adenosylmethionine and a gallic acid ester
WO2019170485A1 (en) 2018-03-09 2019-09-12 Evonik Röhm Gmbh Polymer mixture with resistance against the influence of ethanol
WO2020249505A1 (en) * 2019-06-13 2020-12-17 Evonik Operations Gmbh Powder composition comprising a copolymer mixture and a water-soluble cellulose
CN113950321A (zh) * 2019-06-13 2022-01-18 赢创运营有限公司 包含共聚物混合物和水溶性纤维素的粉末组合物
US12239623B2 (en) 2023-05-15 2025-03-04 Bonafide Health, Llc Sleep-improving compositions and methods of use

Also Published As

Publication number Publication date
CA2606587A1 (en) 2006-11-30
PL1890682T3 (pl) 2017-10-31
SI1890682T1 (sl) 2017-10-30
EP1890682A1 (de) 2008-02-27
US20080193522A1 (en) 2008-08-14
MX363064B (es) 2019-03-06
KR101387835B1 (ko) 2014-04-25
ES2628962T3 (es) 2017-08-04
WO2006125483A1 (de) 2006-11-30
BRPI0610206B1 (pt) 2020-10-06
JP5582701B2 (ja) 2014-09-03
CN101137354A (zh) 2008-03-05
KR20080009213A (ko) 2008-01-25
CN101137354B (zh) 2014-06-11
CA2606587C (en) 2015-05-26
HK1116341A1 (en) 2008-12-19
HUE032869T2 (en) 2017-11-28
MX2007014024A (es) 2008-04-09
BRPI0610206A2 (pt) 2010-06-01
JP2008542211A (ja) 2008-11-27
BRPI0610206B8 (pt) 2022-07-05
IL187535A0 (en) 2008-03-20
EP1890682B1 (de) 2017-05-03

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: EVONIK ROEHM GMBH, 64293 DARMSTADT, DE

8139 Disposal/non-payment of the annual fee