SI2187875T1 - Od pH odvisen farmacevtski sestavek z nadzorovanim sproščanjem za ne-opioide z odpornostjo na vpliv etanola - Google Patents

Od pH odvisen farmacevtski sestavek z nadzorovanim sproščanjem za ne-opioide z odpornostjo na vpliv etanola

Info

Publication number
SI2187875T1
SI2187875T1 SI200731078T SI200731078T SI2187875T1 SI 2187875 T1 SI2187875 T1 SI 2187875T1 SI 200731078 T SI200731078 T SI 200731078T SI 200731078 T SI200731078 T SI 200731078T SI 2187875 T1 SI2187875 T1 SI 2187875T1
Authority
SI
Slovenia
Prior art keywords
opioids
ethanol
influence
pharmaceutical composition
controlled release
Prior art date
Application number
SI200731078T
Other languages
English (en)
Inventor
Hans-Ulrich Petereit
Hema Ravishankar
Ashwini Samel
Original Assignee
Evonik Rohm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Rohm Gmbh filed Critical Evonik Rohm Gmbh
Publication of SI2187875T1 publication Critical patent/SI2187875T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200731078T 2007-09-21 2007-09-25 Od pH odvisen farmacevtski sestavek z nadzorovanim sproščanjem za ne-opioide z odpornostjo na vpliv etanola SI2187875T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN2136CH2007 2007-09-21
PCT/EP2007/060130 WO2009036811A1 (en) 2007-09-21 2007-09-25 Ph-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
EP07820536A EP2187875B1 (en) 2007-09-21 2007-09-25 Ph-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol

Publications (1)

Publication Number Publication Date
SI2187875T1 true SI2187875T1 (sl) 2012-12-31

Family

ID=39278276

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200731078T SI2187875T1 (sl) 2007-09-21 2007-09-25 Od pH odvisen farmacevtski sestavek z nadzorovanim sproščanjem za ne-opioide z odpornostjo na vpliv etanola

Country Status (13)

Country Link
US (1) US9555006B2 (sl)
EP (1) EP2187875B1 (sl)
JP (1) JP5204846B2 (sl)
KR (1) KR101454056B1 (sl)
CN (1) CN101801356B (sl)
BR (1) BRPI0722042B8 (sl)
CA (1) CA2699224C (sl)
ES (1) ES2393805T3 (sl)
IL (1) IL203870A (sl)
MX (1) MX2010003036A (sl)
PL (1) PL2187875T3 (sl)
SI (1) SI2187875T1 (sl)
WO (1) WO2009036811A1 (sl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0815387B8 (pt) 2007-08-13 2021-05-25 Abuse Deterrent Pharmaceutical Llc composição farmacêutica, método para fazer uma composição farmacêutica e uso da composição farmacêutica
ES2532877T3 (es) * 2008-09-24 2015-04-01 Evonik Röhm Gmbh Composición farmacéutica opioide de liberación controlada dependiente del pH con resistencia frente a la influencia del etanol
WO2010034344A1 (en) 2008-09-24 2010-04-01 Evonik Röhm Gmbh Ph-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
CA2741038C (en) * 2008-11-18 2015-01-13 Ucb Pharma S.A. Prolonged release formulations comprising an 2-oxo-1-pyrrolidine derivate
MX339852B (es) * 2008-11-18 2016-06-15 Ucb Pharma Sa Formulaciones de liberacion prolongada que comprenden un derivado de 2-oxo-1-pirrolidina.
PL2408436T3 (pl) 2009-03-18 2017-08-31 Evonik Röhm Gmbh Kompozycja farmaceutyczna o kontrolowanym uwalnianiu z odpornością na wpływ etanolu, wykorzystująca powłokę zawierającą neutralne polimery winylowe i zaróbki
MX365650B (es) 2009-12-02 2019-06-10 Adamas Pharmaceuticals Inc Composiciones de amantadina y metodos para su uso.
US9877925B2 (en) 2010-05-14 2018-01-30 Ethypharm Alcohol-resistant oral pharmaceutical form
FR2959935B1 (fr) * 2010-05-14 2013-02-08 Ethypharm Sa Forme pharmaceutique orale alcoolo-resistante
EP2720681B1 (en) * 2011-06-17 2016-11-23 Evonik Röhm GmbH Coating composition suitable for pharmaceutical or nutraceutical dosage forms
BR112013027484A8 (pt) 2011-06-17 2022-07-05 Evonik Roehm Gmbh Composição farmacêutica ou nutracêutica com resistência gástrica, e uso de um polímero de (met)acrilato
CA2839689C (en) * 2011-06-17 2018-05-01 Evonik Roehm Gmbh Coating composition suitable for pharmaceutical or nutraceutical dosage forms
EP2956124A1 (en) * 2013-02-13 2015-12-23 Evonik Röhm GmbH Multiparticulate pharmaceutical composition comprising a multitude of two kinds of pellets
US10420726B2 (en) 2013-03-15 2019-09-24 Inspirion Delivery Sciences, Llc Abuse deterrent compositions and methods of use
US10154971B2 (en) 2013-06-17 2018-12-18 Adamas Pharma, Llc Methods of administering amantadine
US20150352140A1 (en) * 2014-06-07 2015-12-10 Api Intellectual Property Holdings, Llc Biomass-based dietary supplement
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
CN105769823A (zh) * 2014-12-24 2016-07-20 上海星泰医药科技有限公司 一种左旋盐酸米那普仑缓释胶囊及其制备方法
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
WO2019052845A1 (en) 2017-09-14 2019-03-21 Evonik Röhm Gmbh POLYMER AND PHARMACEUTICAL FORM WITH PROLONGED RELEASE PROPERTIES AND RESISTANCE TO THE INFLUENCE OF ETHANOL
EP3485879A1 (en) * 2017-11-17 2019-05-22 Maat Pharma Pharmaceutical oral formulation comrpsing bacteria
WO2019170485A1 (en) 2018-03-09 2019-09-12 Evonik Röhm Gmbh Polymer mixture with resistance against the influence of ethanol
WO2023166179A1 (en) * 2022-03-03 2023-09-07 Cyprumed Gmbh Improved oral pharmaceutical formulations of therapeutic peptides and proteins

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08143476A (ja) * 1994-11-18 1996-06-04 Japan Tobacco Inc 薬物放出制御膜及び固形製剤
FR2759293B1 (fr) * 1997-02-11 1999-04-30 Ethypharm Lab Prod Ethiques Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
US7374779B2 (en) * 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
JP2005523876A (ja) * 2001-09-26 2005-08-11 ペンウェスト ファーマシューティカルズ カンパニー 乱用の可能性が低減したオピオイド製剤
DE10211289A1 (de) * 2002-03-14 2003-09-25 Basf Ag Kombination von Polyvinylacetat von wasserunlöslichen, säureunlöslichen oder alkaliunlöslichen Polymeren zur Hestellung von Filmüberzügen mit sehr kontrollierter Freisetzung und hoher Stabilität
CA2481091A1 (en) * 2002-04-05 2003-10-23 Penwest Pharmaceuticals Co. Sustained release metoprolol formulations
ATE549015T1 (de) * 2003-10-31 2012-03-15 Hexal Ag Pharmazeutische wirkstoffhaltige formulierung mit überzug
KR20090029856A (ko) * 2005-01-28 2009-03-23 유로-셀띠끄 소시에떼 아노님 알코올 저항성 제형
DE102005024614A1 (de) 2005-05-25 2006-11-30 Röhm Gmbh Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug

Also Published As

Publication number Publication date
MX2010003036A (es) 2010-04-09
CN101801356A (zh) 2010-08-11
CN101801356B (zh) 2016-10-19
PL2187875T3 (pl) 2013-01-31
CA2699224A1 (en) 2009-03-26
KR101454056B1 (ko) 2014-10-27
KR20100063067A (ko) 2010-06-10
US20100221324A1 (en) 2010-09-02
EP2187875A1 (en) 2010-05-26
IL203870A (en) 2015-02-26
JP5204846B2 (ja) 2013-06-05
WO2009036811A1 (en) 2009-03-26
EP2187875B1 (en) 2012-09-05
CA2699224C (en) 2014-12-16
BRPI0722042B1 (pt) 2019-12-10
BRPI0722042A2 (pt) 2014-03-25
BRPI0722042B8 (pt) 2022-07-05
US9555006B2 (en) 2017-01-31
ES2393805T3 (es) 2012-12-28
JP2010539196A (ja) 2010-12-16

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