KR101372752B1 - 유도된 다능성 줄기 세포의 효율적인 확립 방법 - Google Patents

유도된 다능성 줄기 세포의 효율적인 확립 방법 Download PDF

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KR101372752B1
KR101372752B1 KR1020117003453A KR20117003453A KR101372752B1 KR 101372752 B1 KR101372752 B1 KR 101372752B1 KR 1020117003453 A KR1020117003453 A KR 1020117003453A KR 20117003453 A KR20117003453 A KR 20117003453A KR 101372752 B1 KR101372752 B1 KR 101372752B1
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cells
ips
stem cells
cell
pulp stem
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KR20110041521A (ko
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겐이치 데즈카
도시유키 시바타
다카히로 구니사다
나리타카 다마오키
도모코 다케다
신야 야마나카
가즈토시 다카하시
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고꾸리츠 다이가꾸호오징 기후다이가꾸
고쿠리츠 다이가쿠 호진 교토 다이가쿠
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/602—Sox-2
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/603—Oct-3/4
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/604—Klf-4
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/606—Transcription factors c-Myc
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1361—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from dental pulp or dental follicle stem cells
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    • C12N2510/00—Genetically modified cells

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
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  • Transplantation (AREA)
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  • Materials For Medical Uses (AREA)
KR1020117003453A 2008-07-31 2008-10-02 유도된 다능성 줄기 세포의 효율적인 확립 방법 Active KR101372752B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8530808P 2008-07-31 2008-07-31
US61/085,308 2008-07-31
PCT/JP2008/068320 WO2010013359A1 (en) 2008-07-31 2008-10-02 Efficient method for establishing induced pluripotent stem cells

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KR20110041521A KR20110041521A (ko) 2011-04-21
KR101372752B1 true KR101372752B1 (ko) 2014-03-14

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US (1) US20110201110A1 (https=)
JP (1) JP5553178B2 (https=)
KR (1) KR101372752B1 (https=)
AU (1) AU2008360135A1 (https=)
CA (1) CA2732401C (https=)
WO (1) WO2010013359A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8048999B2 (en) 2005-12-13 2011-11-01 Kyoto University Nuclear reprogramming factor
US8129187B2 (en) 2005-12-13 2012-03-06 Kyoto University Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2
US8278104B2 (en) 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
US20090227032A1 (en) 2005-12-13 2009-09-10 Kyoto University Nuclear reprogramming factor and induced pluripotent stem cells
US9213999B2 (en) 2007-06-15 2015-12-15 Kyoto University Providing iPSCs to a customer
JP2008307007A (ja) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
US20110236977A1 (en) * 2008-04-02 2011-09-29 The Trustees Of Columbia University In The City Of New York Dental stem cell differentiation
US20100279404A1 (en) 2008-05-02 2010-11-04 Shinya Yamanaka Method of nuclear reprogramming
US8470308B2 (en) * 2009-01-03 2013-06-25 Ray C. Wasielewski Enhanced medical implant comprising disrupted tooth pulp and tooth particles
US10328103B2 (en) 2009-01-03 2019-06-25 Ray C. Wasielewski Medical treatment composition comprising mammalian dental pulp stem cells
US9487756B2 (en) * 2009-03-20 2016-11-08 Mesoblast, Inc. Production of reprogrammed pluripotent cells
CA2770412C (en) 2009-08-07 2018-09-11 Kyoto University Method of efficiently establishing induced pluripotent stem cells
US8748179B2 (en) 2009-08-31 2014-06-10 Osaka University Method for efficient production of induced pluripotent stem cells utilizing cells derived from oral mucosa
JP2011177140A (ja) * 2010-03-03 2011-09-15 Nippon Dental Univ 幹細胞培養用の無血清培地
KR101334404B1 (ko) * 2011-04-28 2013-12-12 포항공과대학교 산학협력단 배아줄기세포 유래의 인공 마이크로베시클을 이용한 역분화 유도만능줄기세포의 제조방법
JP6128511B2 (ja) * 2012-12-05 2017-05-17 学校法人日本大学 ｉＰＳ細胞の高効率な樹立方法
US9890360B2 (en) 2013-08-28 2018-02-13 Gifu University Method for producing induced pluripotent stem cells
US20150297638A1 (en) * 2014-04-17 2015-10-22 Muhammad Ashraf Chemically induced pluripotent stem cells for safe therapeutic applications
US10443044B2 (en) 2014-04-17 2019-10-15 Ips Heart Generating cardiac progenitor cells from pluripotent stem cells using isoxazole or isoxazole like compounds
KR101656396B1 (ko) * 2014-04-21 2016-09-09 한국생명공학연구원 Oct4 및 Sox2를 이용한 인간 치수강세포의 리프로그래밍 방법 및 이의 용도
HK1257561A1 (zh) * 2015-11-05 2019-10-25 株式会社Cysay 永生化干细胞及其制作方法
US11525119B2 (en) 2016-09-06 2022-12-13 The Children's Medical Center Corporation Immune cells derived from induced pluripotent stem cell
EP3621630A4 (en) 2017-06-14 2021-03-10 The Children's Medical Center HEMATOPOIETIC STEM AND PRECURSOR CELLS FROM HEMOGENIC ENDOTHELIAL CELLS BY EPISOMAL PLASMID GENERAL TRANSFER
US11089356B2 (en) 2019-03-26 2021-08-10 Rovi Guides, Inc. Systems and methods for media content hand-off based on type of buffered data
WO2021150919A1 (en) 2020-01-23 2021-07-29 The Children's Medical Center Corporation Stroma-free t cell differentiation from human pluripotent stem cells
WO2023167243A1 (ja) * 2022-03-01 2023-09-07 学校法人東京医科大学 不死化間葉系幹細胞の上清を含む脱髄疾患治療用医薬組成物、及びその組成物を有効成分とする医薬製剤
WO2023223303A1 (en) 2022-05-20 2023-11-23 Alt Atlas Ltd. Novel cell lines and systems and methods for a machine learning manufacturing software platform that optimize unique functional ingredients and solutions for the biotech and foodtech industries

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8048999B2 (en) * 2005-12-13 2011-11-01 Kyoto University Nuclear reprogramming factor
US8278104B2 (en) * 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
JP2008307007A (ja) * 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Kim, JB. et al., Nature, vol.454, pp.646-650 (온라인 공개 2008.6.29.) *

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Publication number Publication date
WO2010013359A1 (en) 2010-02-04
CA2732401A1 (en) 2010-02-04
AU2008360135A1 (en) 2010-02-04
KR20110041521A (ko) 2011-04-21
CA2732401C (en) 2014-08-05
JP2011529330A (ja) 2011-12-08
JP5553178B2 (ja) 2014-07-16
US20110201110A1 (en) 2011-08-18

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