KR101333577B1 - 개선된 크로마토그래피 매질의 제조방법 및 사용방법 - Google Patents

개선된 크로마토그래피 매질의 제조방법 및 사용방법 Download PDF

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Publication number
KR101333577B1
KR101333577B1 KR1020110074632A KR20110074632A KR101333577B1 KR 101333577 B1 KR101333577 B1 KR 101333577B1 KR 1020110074632 A KR1020110074632 A KR 1020110074632A KR 20110074632 A KR20110074632 A KR 20110074632A KR 101333577 B1 KR101333577 B1 KR 101333577B1
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KR
South Korea
Prior art keywords
polymer
ligand
support
group
polymer support
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KR1020110074632A
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English (en)
Korean (ko)
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KR20120011326A (ko
Inventor
마틴 제이. 디츠
존 제이. 마이크너
Original Assignee
롬 앤드 하아스 컴패니
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Publication of KR20120011326A publication Critical patent/KR20120011326A/ko
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3278—Polymers being grafted on the carrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/20—Anion exchangers for chromatographic processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)
KR1020110074632A 2010-07-28 2011-07-27 개선된 크로마토그래피 매질의 제조방법 및 사용방법 Expired - Fee Related KR101333577B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36837910P 2010-07-28 2010-07-28
US61/368,379 2010-07-28

Publications (2)

Publication Number Publication Date
KR20120011326A KR20120011326A (ko) 2012-02-07
KR101333577B1 true KR101333577B1 (ko) 2013-11-28

Family

ID=44674145

Family Applications (1)

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KR1020110074632A Expired - Fee Related KR101333577B1 (ko) 2010-07-28 2011-07-27 개선된 크로마토그래피 매질의 제조방법 및 사용방법

Country Status (5)

Country Link
US (1) US9067195B2 (enExample)
EP (1) EP2412434A3 (enExample)
JP (1) JP5631271B2 (enExample)
KR (1) KR101333577B1 (enExample)
CN (1) CN102343256B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015005937A2 (pt) 2012-09-17 2017-07-04 Grace W R & Co meios e dispositivos cromatográficos
EP4615169A3 (en) * 2014-05-15 2025-12-10 Mayo Foundation for Medical Education and Research Solution target for cyclotron production of radiometals
WO2018011600A1 (en) * 2016-07-14 2018-01-18 Puridify Ltd. Functionalised chromatography medium comprising polymer nanofibres and process of preparation thereof
DE102017000631A1 (de) 2017-01-24 2018-07-26 Sartorius Stedim Biotech Gmbh Chromatographiemedium mit gebundenen Mikroglobuli und Verfahren zu dessen Herstellung
CN111001188B (zh) * 2019-12-27 2021-11-16 纳谱分析技术（苏州）有限公司 一种反相分离介质及其制备方法和应用
WO2022087805A1 (en) * 2020-10-27 2022-05-05 Guangzhou Bioseal Biotech Co., Ltd. Chromatographic matrix and uses thereof for purification of fibronectin

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030125204A1 (en) 2000-06-27 2003-07-03 Alois Jungbauer Chromatography material and a process of manufacturing that material
US20040059040A1 (en) * 2002-06-27 2004-03-25 Per Moller Adsorbent material and method of preparing an adsorbent material
US20070193954A1 (en) * 2004-04-05 2007-08-23 Philippe Busson Method of preparing a separation matrix

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE417431B (sv) * 1975-12-12 1981-03-16 Pharmacia Fine Chemicals Ab Dextranderivatgel for elektroforetisk separation
JPS55123610A (en) * 1979-03-17 1980-09-24 Nichiden Kagaku Kk Modified starch and its preparation
JPS57155212A (en) * 1981-03-20 1982-09-25 Kanegafuchi Chem Ind Co Ltd Modified polyvinyl chloride resin composition
DE3811042A1 (de) 1988-03-31 1989-10-19 Merck Patent Gmbh Ionenaustauscher
JPH05170845A (ja) 1991-12-20 1993-07-09 Nippon Paint Co Ltd 有機ポリマー微粒子およびその製法
DE4333821A1 (de) * 1993-10-04 1995-04-06 Merck Patent Gmbh Ionenaustauscher
JP3446274B2 (ja) * 1993-12-21 2003-09-16 三菱化学株式会社 分離剤の製造方法
TW307775B (en) * 1994-02-15 1997-06-11 Novartis Erfind Verwalt Gmbh Unsaturated carbohydrate derivatives, polymers thereof and their use
JP3520381B2 (ja) 1994-11-07 2004-04-19 セイコーエプソン株式会社 インクジェット記録用インク組成物
SE9700383D0 (sv) * 1997-02-04 1997-02-04 Pharmacia Biotech Ab An adsorption/separation method and a medium for adsorption/separation
SE9700769D0 (sv) * 1997-03-04 1997-03-04 Pharmacia Biotech Ab Matriser för separation och separation som utnyttjar matriserna
EP1591462A3 (en) * 1999-01-29 2006-05-03 Amersham Biosciences KK Temperature-responsive polymer compound and process for producing the same
JP4433617B2 (ja) 2001-01-24 2010-03-17 東ソー株式会社 アニオン交換体、その製造方法及びそれを用いた用途
CA2464086C (en) * 2001-11-26 2011-01-18 Amersham Biosciences Ab Post-modification of a porous support
US6763243B2 (en) 2002-07-02 2004-07-13 Motorola, Inc. Method and apparatus for providing prioritized multi-party communication sessions in a wireless communication system
EP2295472B1 (en) * 2005-09-16 2017-06-28 Rohm and Haas Company Swellable particles

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030125204A1 (en) 2000-06-27 2003-07-03 Alois Jungbauer Chromatography material and a process of manufacturing that material
US20040059040A1 (en) * 2002-06-27 2004-03-25 Per Moller Adsorbent material and method of preparing an adsorbent material
US20070193954A1 (en) * 2004-04-05 2007-08-23 Philippe Busson Method of preparing a separation matrix

Also Published As

Publication number Publication date
EP2412434A2 (en) 2012-02-01
JP2012032391A (ja) 2012-02-16
CN102343256B (zh) 2013-11-06
US9067195B2 (en) 2015-06-30
CN102343256A (zh) 2012-02-08
US20120024792A1 (en) 2012-02-02
EP2412434A3 (en) 2013-03-06
JP5631271B2 (ja) 2014-11-26
KR20120011326A (ko) 2012-02-07

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