KR101314880B1 - 관절류머티즘 치료제 - Google Patents
관절류머티즘 치료제 Download PDFInfo
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- KR101314880B1 KR101314880B1 KR1020117024354A KR20117024354A KR101314880B1 KR 101314880 B1 KR101314880 B1 KR 101314880B1 KR 1020117024354 A KR1020117024354 A KR 1020117024354A KR 20117024354 A KR20117024354 A KR 20117024354A KR 101314880 B1 KR101314880 B1 KR 101314880B1
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| PCT/JP2010/054763 WO2010107108A1 (ja) | 2009-03-19 | 2010-03-19 | 関節リウマチ治療剤 |
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| EP3056568B1 (en) | 2006-03-31 | 2021-09-15 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
| ES2564392T3 (es) | 2007-01-23 | 2016-03-22 | Shinshu University | Inhibidores de IL-6 para el tratamiento de rechazo crónico |
| US10717781B2 (en) | 2008-06-05 | 2020-07-21 | National Cancer Center | Neuroinvasion inhibitor |
| TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
| ES2932398T3 (es) | 2010-05-28 | 2023-01-18 | Chugai Pharmaceutical Co Ltd | Potenciador de la respuesta de las células T antitumorales |
| US10782290B2 (en) | 2013-06-11 | 2020-09-22 | National Center Of Neurology And Psychiatry | Method for predicting post-therapy prognosis of relapsing-remitting multiple sclerosis (RRMS) patient, and method for determining applicability of novel therapy |
| BR112017014067B1 (pt) | 2015-02-27 | 2021-01-12 | Chugai Seiyaku Kabushiki Kaisha | usos de um anticorpo receptor de il-6 para no tratamento de doenças relacionadas a il-6 |
| US10697883B2 (en) | 2015-05-19 | 2020-06-30 | National Center Of Neurology And Psychiatry | Method for determining application of therapy to multiple sclerosis (MS) patient |
| JP7185884B2 (ja) | 2017-05-02 | 2022-12-08 | 国立研究開発法人国立精神・神経医療研究センター | Ｉｌ－６及び好中球の関連する疾患の治療効果の予測及び判定方法 |
| WO2019078344A1 (ja) | 2017-10-20 | 2019-04-25 | 学校法人兵庫医科大学 | 抗ｉｌ－６受容体抗体を含有する術後の癒着を抑制するための医薬組成物 |
| US20210363238A1 (en) | 2018-01-31 | 2021-11-25 | Motokazu Kato | Therapeutic agent for asthma containing il-6 inhibitor |
| CN113660951A (zh) | 2019-03-29 | 2021-11-16 | 中外制药株式会社 | 含有抗il-6受体抗体的抑制bbb功能低下的抑制剂 |
| CN114072173A (zh) | 2019-04-17 | 2022-02-18 | 国立大学法人广岛大学 | 以联合施用il-6抑制剂和ccr2抑制剂为特征的泌尿系统癌症治疗剂 |
| US20240158518A1 (en) | 2021-03-12 | 2024-05-16 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition for treatment or prevention of myasthenia gravis |
| WO2025198912A1 (en) | 2024-03-21 | 2025-09-25 | Hoffmann-La Roche Inc. | Methods of treating myasthenia gravis |
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| CA2203182C (en) * | 1994-10-21 | 2009-11-24 | Asao Katsume | Remedy for diseases caused by il-6 production |
| MX2007007935A (es) * | 2004-12-28 | 2007-12-06 | Innate Pharma Sa | Anticuerpos monoclonales contra nkg2a. |
| WO2009010539A2 (en) * | 2007-07-19 | 2009-01-22 | Ablynx. N.V. | Receptor for interleukin-6 (il-6) from macaca fascicularis |
| AU2008304756B8 (en) * | 2007-09-26 | 2015-02-12 | Chugai Seiyaku Kabushiki Kaisha | Anti-IL-6 receptor antibody |
| RU2526512C2 (ru) * | 2007-09-26 | 2014-08-20 | Чугаи Сейяку Кабусики Кайся | Модифицированная константная область антитела |
| CA2721052C (en) * | 2008-04-11 | 2023-02-21 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
| TWI440469B (zh) * | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
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| WO2008020079A1 (en) | 2006-08-18 | 2008-02-21 | Ablynx N.V. | Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling |
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| JP4809930B2 (ja) | 2011-11-09 |
| TWI457134B (zh) | 2014-10-21 |
| JP2011219478A (ja) | 2011-11-04 |
| KR20110139734A (ko) | 2011-12-29 |
| WO2010107108A1 (ja) | 2010-09-23 |
| JPWO2010107108A1 (ja) | 2012-09-20 |
| RU2011142183A (ru) | 2013-04-27 |
| RU2524152C2 (ru) | 2014-07-27 |
| TW201034685A (en) | 2010-10-01 |
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