KR101232499B1 - 마이코톡신을 확인하는 장치 및 방법 - Google Patents

마이코톡신을 확인하는 장치 및 방법 Download PDF

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Publication number
KR101232499B1
KR101232499B1 KR1020087018026A KR20087018026A KR101232499B1 KR 101232499 B1 KR101232499 B1 KR 101232499B1 KR 1020087018026 A KR1020087018026 A KR 1020087018026A KR 20087018026 A KR20087018026 A KR 20087018026A KR 101232499 B1 KR101232499 B1 KR 101232499B1
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South Korea
Prior art keywords
mycotoxin
binding partner
waveguide
mycotoxins
thin film
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English (en)
Korean (ko)
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KR20080083682A (ko
Inventor
옌스 부르마이스테르
잉그마르 도른
우베 라베
이솔데 호이제르-한
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바이엘 크롭사이언스 아게
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/648Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769Measurement method of reaction-produced change in sensor
    • G01N2021/7786Fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37Assays involving biological materials from specific organisms or of a specific nature from fungi

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Optics & Photonics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1020087018026A 2005-12-23 2006-12-13 마이코톡신을 확인하는 장치 및 방법 Expired - Fee Related KR101232499B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005062377A DE102005062377A1 (de) 2005-12-23 2005-12-23 Vorrichtung und Verfahren zum Nachweis von Mykotoxinen
DE102005062377.8 2005-12-23
PCT/EP2006/012000 WO2007079893A1 (de) 2005-12-23 2006-12-13 Vorrichtung und verfahren zum nachweis von mykotoxinen

Publications (2)

Publication Number Publication Date
KR20080083682A KR20080083682A (ko) 2008-09-18
KR101232499B1 true KR101232499B1 (ko) 2013-02-12

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KR1020087018026A Expired - Fee Related KR101232499B1 (ko) 2005-12-23 2006-12-13 마이코톡신을 확인하는 장치 및 방법

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Country Link
US (1) US20090081808A1 (enExample)
EP (1) EP1966594B1 (enExample)
JP (1) JP2009520956A (enExample)
KR (1) KR101232499B1 (enExample)
CN (1) CN101384896A (enExample)
AR (1) AR058616A1 (enExample)
AU (1) AU2006334802B2 (enExample)
BR (1) BRPI0620376A2 (enExample)
CA (1) CA2634559A1 (enExample)
CR (1) CR10087A (enExample)
DE (1) DE102005062377A1 (enExample)
DK (1) DK1966594T3 (enExample)
EA (1) EA013337B1 (enExample)
ES (1) ES2400919T3 (enExample)
PL (1) PL1966594T3 (enExample)
PT (1) PT1966594E (enExample)
UA (1) UA97792C2 (enExample)
WO (1) WO2007079893A1 (enExample)
ZA (1) ZA200805457B (enExample)

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DE102009016712A1 (de) 2009-04-09 2010-10-14 Bayer Technology Services Gmbh Einweg-Mikrofluidik-Testkassette zur Bioassay von Analyten
AP2011005905A0 (en) 2009-04-09 2011-10-31 Bayer Cropscience Ag Device and method for the verification and quantitative analysis of analytes, particularly mycotoxins.
WO2011023230A1 (en) * 2009-08-27 2011-03-03 Foss Analytical Ab Method of extracting mycotoxins from cereal grains
CN101666752B (zh) * 2009-09-29 2011-07-20 济南大学 一种糖基功能化细菌毒素分子印迹柱的制备方法及应用
JP5840845B2 (ja) * 2011-02-25 2016-01-06 国立研究開発法人農業・食品産業技術総合研究機構 危害要因定量方法、危害要因定量装置、および、プログラム
ITMO20110109A1 (it) * 2011-05-11 2012-11-12 Generon S R L Metodo per l'analisi di aflatossine nel latte e nei derivati del latte
CN102279268A (zh) * 2011-07-29 2011-12-14 上海交通大学 同时检测玉米赤霉烯酮与伏马毒素的方法
CN102443585A (zh) * 2011-11-25 2012-05-09 国家纳米技术与工程研究院 玉米赤霉烯酮核酸适体及其应用
CN102517290A (zh) * 2011-11-25 2012-06-27 国家纳米技术与工程研究院 伏马毒素b2核酸适体及其应用
EP2810070B1 (en) * 2012-02-03 2020-04-01 Charm Sciences Inc. Extraction of mycotoxins
JP5731016B2 (ja) * 2012-04-27 2015-06-10 キリン株式会社 リガンドを高感度に検出する核酸分子並びに該核酸分子のスクリーニング方法および該核酸分子の感度の最適化方法
CN103743913B (zh) * 2014-01-23 2015-07-08 福建农林大学 快速鉴定与黄曲霉毒素b1互作的宿主蛋白的方法
CN104293793B (zh) * 2014-07-24 2018-05-18 江南大学 一种特异识别t-2毒素的寡核苷酸适配体
FR3028318B1 (fr) * 2014-11-12 2025-10-03 Phuong Lan Tran Procede et dispositif de tri selectif, specifique et simultane de cellules rares cibles dans un echantillon biologique
CN104593374B (zh) * 2015-03-02 2017-05-17 江南大学 一种特异识别棒曲霉素的寡核苷酸适配体
EP3294750B1 (en) 2015-05-08 2023-10-25 Waters Technologies Corporation Composition and methods for extracting mycotoxins
KR102042661B1 (ko) * 2015-08-06 2019-11-08 광주과학기술원 타겟 물질 검출용 복합체 및 이를 이용한 타겟 물질 검출방법
DE202016106024U1 (de) 2016-10-26 2016-11-08 Matthias Godejohann Vorrichtung zur Halterung zu einer Halbleiterplatte
CN108614054A (zh) * 2016-12-12 2018-10-02 北京农学院 基于聚苯乙烯-二乙烯苯树脂为载体的真菌毒素免疫亲和柱的制备方法
CN108490169B (zh) * 2018-03-27 2021-09-03 广东一家人食品有限公司 一种米粉中真菌毒素的双水相萃取联合酶联免疫检测的方法
BR112021025933A2 (pt) 2019-07-03 2022-02-08 Intervet Int Bv Desoxinivalenol conjugado para proteger contra micotoxicose
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Also Published As

Publication number Publication date
PT1966594E (pt) 2013-03-13
AR058616A1 (es) 2008-02-13
EP1966594B1 (de) 2013-01-23
UA97792C2 (ru) 2012-03-26
AU2006334802A1 (en) 2007-07-19
KR20080083682A (ko) 2008-09-18
ZA200805457B (en) 2010-02-24
AU2006334802B2 (en) 2013-03-14
DE102005062377A1 (de) 2007-06-28
CR10087A (es) 2009-01-27
JP2009520956A (ja) 2009-05-28
EA200801588A1 (ru) 2008-12-30
BRPI0620376A2 (pt) 2011-11-08
EP1966594A1 (de) 2008-09-10
DK1966594T3 (da) 2013-04-15
CN101384896A (zh) 2009-03-11
CA2634559A1 (en) 2007-07-19
ES2400919T3 (es) 2013-04-15
PL1966594T3 (pl) 2013-06-28
EA013337B1 (ru) 2010-04-30
WO2007079893A1 (de) 2007-07-19
US20090081808A1 (en) 2009-03-26

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