CN101384896A - 用于检测真菌毒素的设备和方法 - Google Patents

用于检测真菌毒素的设备和方法 Download PDF

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Publication number
CN101384896A
CN101384896A CNA2006800532011A CN200680053201A CN101384896A CN 101384896 A CN101384896 A CN 101384896A CN A2006800532011 A CNA2006800532011 A CN A2006800532011A CN 200680053201 A CN200680053201 A CN 200680053201A CN 101384896 A CN101384896 A CN 101384896A
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CN
China
Prior art keywords
mycotoxin
thin
film waveguide
mycotoxins
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006800532011A
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English (en)
Chinese (zh)
Inventor
J·伯梅斯特
I·多恩
U·拉比
I·豪瑟-哈恩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer CropScience AG
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Bayer AG
Bayer CropScience AG
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Publication of CN101384896A publication Critical patent/CN101384896A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Optics & Photonics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CNA2006800532011A 2005-12-23 2006-12-13 用于检测真菌毒素的设备和方法 Pending CN101384896A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005062377A DE102005062377A1 (de) 2005-12-23 2005-12-23 Vorrichtung und Verfahren zum Nachweis von Mykotoxinen
DE102005062377.8 2005-12-23

Publications (1)

Publication Number Publication Date
CN101384896A true CN101384896A (zh) 2009-03-11

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ID=37909504

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CNA2006800532011A Pending CN101384896A (zh) 2005-12-23 2006-12-13 用于检测真菌毒素的设备和方法

Country Status (19)

Country Link
US (1) US20090081808A1 (enExample)
EP (1) EP1966594B1 (enExample)
JP (1) JP2009520956A (enExample)
KR (1) KR101232499B1 (enExample)
CN (1) CN101384896A (enExample)
AR (1) AR058616A1 (enExample)
AU (1) AU2006334802B2 (enExample)
BR (1) BRPI0620376A2 (enExample)
CA (1) CA2634559A1 (enExample)
CR (1) CR10087A (enExample)
DE (1) DE102005062377A1 (enExample)
DK (1) DK1966594T3 (enExample)
EA (1) EA013337B1 (enExample)
ES (1) ES2400919T3 (enExample)
PL (1) PL1966594T3 (enExample)
PT (1) PT1966594E (enExample)
UA (1) UA97792C2 (enExample)
WO (1) WO2007079893A1 (enExample)
ZA (1) ZA200805457B (enExample)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102279268A (zh) * 2011-07-29 2011-12-14 上海交通大学 同时检测玉米赤霉烯酮与伏马毒素的方法
CN102443585A (zh) * 2011-11-25 2012-05-09 国家纳米技术与工程研究院 玉米赤霉烯酮核酸适体及其应用
CN102460127A (zh) * 2009-04-09 2012-05-16 拜尔农作物科学股份公司 用于识别和定量分析被分析物，特别是真菌毒素的装置和方法
CN102517290A (zh) * 2011-11-25 2012-06-27 国家纳米技术与工程研究院 伏马毒素b2核酸适体及其应用
CN104593374A (zh) * 2015-03-02 2015-05-06 江南大学 一种特异识别棒曲霉素的寡核苷酸适配体
WO2016011845A1 (zh) * 2014-07-24 2016-01-28 江南大学 特异识别t-2毒素的寡核苷酸适配体
CN107709348A (zh) * 2015-05-08 2018-02-16 沃特世科技公司 用于提取真菌毒素的组合物和方法
CN108490169A (zh) * 2018-03-27 2018-09-04 厦门市诚安毅科技有限公司 一种米粉中真菌毒素的双水相萃取联合酶联免疫检测的方法

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DE102009016712A1 (de) 2009-04-09 2010-10-14 Bayer Technology Services Gmbh Einweg-Mikrofluidik-Testkassette zur Bioassay von Analyten
WO2011023230A1 (en) * 2009-08-27 2011-03-03 Foss Analytical Ab Method of extracting mycotoxins from cereal grains
CN101666752B (zh) * 2009-09-29 2011-07-20 济南大学 一种糖基功能化细菌毒素分子印迹柱的制备方法及应用
JP5840845B2 (ja) * 2011-02-25 2016-01-06 国立研究開発法人農業・食品産業技術総合研究機構 危害要因定量方法、危害要因定量装置、および、プログラム
ITMO20110109A1 (it) * 2011-05-11 2012-11-12 Generon S R L Metodo per l'analisi di aflatossine nel latte e nei derivati del latte
EP2810070B1 (en) * 2012-02-03 2020-04-01 Charm Sciences Inc. Extraction of mycotoxins
JP5731016B2 (ja) * 2012-04-27 2015-06-10 キリン株式会社 リガンドを高感度に検出する核酸分子並びに該核酸分子のスクリーニング方法および該核酸分子の感度の最適化方法
CN103743913B (zh) * 2014-01-23 2015-07-08 福建农林大学 快速鉴定与黄曲霉毒素b1互作的宿主蛋白的方法
FR3028318B1 (fr) * 2014-11-12 2025-10-03 Phuong Lan Tran Procede et dispositif de tri selectif, specifique et simultane de cellules rares cibles dans un echantillon biologique
KR102042661B1 (ko) * 2015-08-06 2019-11-08 광주과학기술원 타겟 물질 검출용 복합체 및 이를 이용한 타겟 물질 검출방법
DE202016106024U1 (de) 2016-10-26 2016-11-08 Matthias Godejohann Vorrichtung zur Halterung zu einer Halbleiterplatte
CN108614054A (zh) * 2016-12-12 2018-10-02 北京农学院 基于聚苯乙烯-二乙烯苯树脂为载体的真菌毒素免疫亲和柱的制备方法
BR112021025933A2 (pt) 2019-07-03 2022-02-08 Intervet Int Bv Desoxinivalenol conjugado para proteger contra micotoxicose
JP7387524B2 (ja) * 2020-04-06 2023-11-28 Ｔｉａｎｍａ Ｊａｐａｎ株式会社 蛍光を用いた免疫分析法で測定するための試料溶液の調製方法、測定用セル、測定キットおよび試料溶液の調製装置

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US5814565A (en) * 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
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WO2002020873A2 (de) * 2000-09-05 2002-03-14 Zeptosens Ag Verfahren zur abscheidung von mono- und mehrfachschichten von organophosphor- und -phosphonsäuren und deren salzen sowie deren verwendung
US6812380B2 (en) * 2001-03-27 2004-11-02 Pioneer Hi-Bred International, Inc. Compositions and methods of zearalenone detoxification
JP4203826B2 (ja) * 2003-09-29 2009-01-07 独立行政法人産業技術総合研究所 自動分析方法及び装置
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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102460127A (zh) * 2009-04-09 2012-05-16 拜尔农作物科学股份公司 用于识别和定量分析被分析物，特别是真菌毒素的装置和方法
CN102279268A (zh) * 2011-07-29 2011-12-14 上海交通大学 同时检测玉米赤霉烯酮与伏马毒素的方法
CN102443585A (zh) * 2011-11-25 2012-05-09 国家纳米技术与工程研究院 玉米赤霉烯酮核酸适体及其应用
CN102517290A (zh) * 2011-11-25 2012-06-27 国家纳米技术与工程研究院 伏马毒素b2核酸适体及其应用
WO2016011845A1 (zh) * 2014-07-24 2016-01-28 江南大学 特异识别t-2毒素的寡核苷酸适配体
CN104293793B (zh) * 2014-07-24 2018-05-18 江南大学 一种特异识别t-2毒素的寡核苷酸适配体
CN104593374A (zh) * 2015-03-02 2015-05-06 江南大学 一种特异识别棒曲霉素的寡核苷酸适配体
CN104593374B (zh) * 2015-03-02 2017-05-17 江南大学 一种特异识别棒曲霉素的寡核苷酸适配体
CN107709348A (zh) * 2015-05-08 2018-02-16 沃特世科技公司 用于提取真菌毒素的组合物和方法
CN108490169A (zh) * 2018-03-27 2018-09-04 厦门市诚安毅科技有限公司 一种米粉中真菌毒素的双水相萃取联合酶联免疫检测的方法

Also Published As

Publication number Publication date
PT1966594E (pt) 2013-03-13
AR058616A1 (es) 2008-02-13
EP1966594B1 (de) 2013-01-23
UA97792C2 (ru) 2012-03-26
AU2006334802A1 (en) 2007-07-19
KR20080083682A (ko) 2008-09-18
ZA200805457B (en) 2010-02-24
AU2006334802B2 (en) 2013-03-14
DE102005062377A1 (de) 2007-06-28
CR10087A (es) 2009-01-27
KR101232499B1 (ko) 2013-02-12
JP2009520956A (ja) 2009-05-28
EA200801588A1 (ru) 2008-12-30
BRPI0620376A2 (pt) 2011-11-08
EP1966594A1 (de) 2008-09-10
DK1966594T3 (da) 2013-04-15
CA2634559A1 (en) 2007-07-19
ES2400919T3 (es) 2013-04-15
PL1966594T3 (pl) 2013-06-28
EA013337B1 (ru) 2010-04-30
WO2007079893A1 (de) 2007-07-19
US20090081808A1 (en) 2009-03-26

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