KR101183893B1 - Cosmetic composition having improving ability for atopy dermatitis and method for using the same - Google Patents

Abstract

The present invention relates to a cosmetic composition having atopic dermatitis improving ability and a method of using the same. In the present invention, a combination of herbal medicines and treatment methods used for soothing skin and atopic dermatitis in oriental medicine, raw materials and treatment methods used for atopic dermatitis in Western medicine, and raw materials and treatment methods used for atopic dermatitis in folk medicine are irritated to the skin. It provides a topical composition for treating atopic dermatitis, which is a fundamental treatment of atopic dermatitis, and has no cumulative side effects.

Atopic dermatitis, cosmetics, herbal medicine, wood vinegar, ceramide

Description

Cosmetic composition having atopic dermatitis improving ability and method of using the same {Cosmetic composition having improving ability for atopy dermatitis and method for using the same}

The present invention relates to a cosmetic composition having atopic dermatitis improving ability and a method of using the same.

Atopic dermatitis is a syndrome that plagues many people because of itchy, dry, sensitive skin. Symptoms include red rashes, dark and dry skin, thickening and drooling. The area that occurs is the inside of the joint, which is good for the inside of the elbow, the back of the knee, and the neck. This atopic dermatitis mainly occurs in children under 5 years of age with a frequency of 3 to 5%, up to 10%.

The number of infants with atopic dermatitis in Korea is estimated to be 385,419.The causes include recent environmental pollution due to industrialization (industrialization), dietary changes such as eating meat and greasy high-calorie foods, stress, and lack of sleep. Since 20 years ago, the number of patients has increased every year due to changes in life patterns, and juniors and adults have found symptoms of atopic dermatitis.

Atopic dermatitis in Western medicine is a chronic inflammatory skin lesion that has a chronic recurrent course, characterized by pruritus, characteristic lesion distribution, and family history of allergies. The diagnosis of atopic dermatitis is mainly based on the diagnostic criteria published by Hanifin in 1980. have.

To date, there is no doubt that atopic dermatitis is one of the etiologies of immunological allergic reactions, but immunological aspects alone are not enough to explain the various clinical features and symptoms of atopic dermatitis.

Recently, abnormality of the barrier function, which is a skin-specific function, has been described as one of the important factors as a cause of atopic dermatitis.

The characteristics of this atopic dermatitis include Transepidermal Water Loss (TEWL), decreased water content in the stratum corneum, water binding capacity, water holding capacity, skin pH, and dry skin in patients with atopic dermatitis. , Epidermal lipid reduction, skin barrier damage, relative volume of lamellar body, and increased frequency of irritant contact dermatitis.As a result, atopic dermatitis is characterized by a decrease in the amount of ceramide in the stratum corneum. Decreased skin barrier function, dry skin, pruritus are also caused by stimulation response to various stimulants.

On the other hand, in oriental medicine, atopic dermatitis is referred to as internal, typhoon (胎 風), Taegeok (胎 赤), Taeseon (胎 癬), etc. In China, it is also called infant eczema and bilateral infection.

The cause of atopic dermatitis is, in short, the cause of heat buildup in the body, which is explained in more detail, sensitive constitution (congenital factor) that reacts excessively to the release of heat, high calorie foods that promote the development of heat, stress, It is reported that atopic dermatitis is common in children because of the three causes described, such as changed life patterns such as sleep deprivation and the period of physiological heat generation in infants and toddlers.

Western medicine uses antihistamines and steroids to treat atopic dermatitis. These substances are naturally produced in our body, and they function to cure inflammation. When a large amount is administered in the long term, the external supply relationship causes many side effects in our body. Examples include metabolic disorders, gastric mucosal weakness, gastric wall inflammation, gastric ulcers, diabetes, growth disorders, osteoporosis, and immune function suppression. In addition, therapeutic agents for treating atopic dermatitis include ceramide, machi, and rooibos.

As such, conventional herbal extracts and / or medicinal ingredients have been used to control atopic dermatitis, and related patents include Patent Documents 1 to 5 and the like. For example, Patent Literatures 1 and 2 disclose cosmetic compositions containing at least one complex herbal extract selected from Ogapi, Ohaengcho, Cho Kyu-geun, Sewao, and Astronomical Dong, and nano ceramides or detergents. The present invention discloses a cosmetic using a natural extract obtained by mixing stalk, ringworm, saengsaeng, and eosungcho.

As described above, many studies on atopic dermatitis have been conducted in oriental medicine, western medicine, and folk medicine. However, due to problems such as effects and human hazards, complete treatment was not possible.

Patent Document 1: Korean Patent No. 10-0824958

Patent Document 2: Korea Patent Registration No. 10-0831594

Patent Document 3: Korea Patent No. 10-0633041

Patent Document 4: Korea Patent No. 10-0878353

Patent Document 5: Korea Patent Registration No. 10-0733869

Therefore, in the present invention, the herbal medicine and treatment method used for soothing skin and atopic dermatitis in oriental medicine, the raw material and treatment method used for atopic dermatitis in Western medicine, and the combination and the treatment method used for atopic dermatitis in folk medicine are irritated to the skin. It is possible to develop a topical composition for treating atopic dermatitis, which is essentially free of atopic dermatitis, and has no cumulative side effects, and the present invention has been completed based thereon.

Accordingly, it is an object of the present invention to provide a cosmetic composition having an effect of improving skin sedation and atopic dermatitis using therapies and ingredients, such as oriental, herbal, folk remedies.

Another object of the present invention to provide a method for most efficiently using the cosmetic composition having the ability to improve atopic dermatitis.

Cosmetic composition having an atopic dermatitis improving ability of the present invention for achieving the above object 35 weight of the first external preparation comprising 1 to 20% by weight of the first herbal extract consisting of changja, ringworm and sunscreen and 1 to 15% by weight of wood vinegar solution %; 35% by weight of the second external preparation comprising 1-20% by weight of the second herb extract composed of Angelica, Korean herb and sundae, 1-15% by weight of ceramide and 1-15% by weight of vinegar solution; And 30% by weight of Chinese medicine powder consisting of white, former and white paper.

In the cosmetic composition, the first herbal extract is characterized in that extracted by heating the herbal medicine consisting of 10 to 50% by weight, 20 to 60% by weight and whitening skin 10% to 50% by weight in the presence of a solvent.

In the cosmetic composition of the present invention, the second herbal extract is characterized in that extracted by heating the herbal medicine consisting of 20 to 60% by weight, 10 to 50% by weight and 10 to 50% by weight in the presence of a solvent.

In the cosmetic composition of the present invention, the herbal powder is characterized by consisting of 10 to 40% by weight, 10 to 40% by weight and 10 to 40% by weight of white paper.

In the cosmetic composition of the present invention, the first herbal extract is characterized in that it further comprises a ginseng, casualties or a mixture thereof.

In the cosmetic composition of the present invention, the herbal powder is characterized in that it further comprises ringworm skin, white sewage or a mixture thereof.

In the cosmetic composition of the present invention, the composition is characterized in that the cream, lotion, essence, skin, powder, foundation, sunscreen, body lotion or body cleanser.

In order to achieve the another object of the present invention, the method of using the cosmetic composition having an atopic dermatitis improving ability is 1 to 20% by weight and 1 to 15% by weight of a herbaceous acid extract, the first herb extract consisting of ringworm and sediment Applying a first external preparation comprising; Applying to the affected part a second external preparation comprising 1 to 20% by weight of a second herb extract composed of Angelica, soybean and sundae, 1 to 15% by weight of ceramide, and 1 to 15% by weight of wood vinegar; And applying a herbal powder consisting of platinum, anterior and white paper to the affected part.

As mentioned above, many studies on atopic dermatitis have been conducted in herbal medicine, Western medicine, and folk medicine. However, due to problems such as effects and human hazards, complete treatment was not possible. Accordingly, the present invention can relieve the pain of infants (3,854,184) currently suffering from atopic dermatitis in Korea, as well as treat atopic dermatitis patients reaching 10% of the world's population.

Looking at the present invention in more detail as follows.

Human skin is composed of epidermal layer, dermis layer and subcutaneous fat layer. The epidermal layer is divided into basal layer, play layer, granule layer, transparent layer and stratum corneum. The stratum corneum consists of a large number of cell layers tightly packaged as dead cells located at the outermost surface of the skin and is present in a mixed phase with strong bonds between fibers and substrates. The cells are filled with an amorphous matrix and have a fairly flat structure that is tightly compacted to provide a water proof function that does not pass moisture.

Keratinocytes are surrounded by a modified cell membrane called the envelope, which is made up of unique cell membranes. Constituents of the stratum corneum are keratin 50%, fat 20%, aqueous solution 23%, and water 7%. The thickness of the stratum corneum varies depending on the moisture content. When the amount of water decreases, each mass becomes thicker, which makes the skin rough, and promotes atopic dermatitis and skin aging.

The function of the stratum corneum is that most of the fatty components are polar lipids, which are insoluble in protein solvents to prevent infiltration of substances, and also to prevent separation and leakage of components, and the fiber part is involved in binding, flexibility and elastic recovery. In this case, the substrate part is responsible for preventing the positional change by collecting the fibers. In particular, it prevents the penetration of moisture into the skin and prevents the loss of body fluids to the outside.

The most important of these is the lipids present in the epidermis, the sebaceous lipids secreted from the sebaceous glands, and the intercelluar lipids secreted between the epidermal cells.The skin has elasticity, flexibility, moisturization, and skin barrier function. It is more important to maintain. The epidermal lipids are composed of 50% ceramide, 25% cholesterol, 12% free fatty acid, 5% cholesterol ester and 3% phospholipid.

Ceramide is a type of sphingo lipid with a structure in which fatty acids are linked to sphingosine or phytosphingosine.

This ceramide acts as a lipid barrier to inhibit the evaporation of water and maintains the structure of the stratum corneum. The ceramide suppresses the evaporation of water and also contains water, so the skin performs optimal metabolic functions. Provide an optimal environment. Ceramide is decomposed into phytosphingosine on the surface of the skin to protect the skin from external harmful environment such as antibacterial and anti-inflammatory of the skin.

When the content of ceramide with this function decreases, the evaporation of water increases, causing severe dryness, various skin diseases, senile dry skin and itching, and the skin loses its elasticity and wrinkles, leading to loss of health. This is the main cause of atopic dermatitis. Therefore, in the present invention, the ceramide is included as an essential ingredient.

On the other hand, wood vinegar is generally made by collecting and cooling the crude wood vinegar produced by collecting and cooling the smoke generated when carbonizing the wood of oak trees. The constituents of the wood vinegar are 85% water and 15% trace components (organic minerals), and the main components excluding moisture contain 200 or more kinds of compounds including acetic acid and the like.

Trace ingredients include acids, phenols, neutrals, carbonyls, and basic ingredients, especially fats, saturated fatty acids, cholesterol, carbohydrates, fiber, sugars, moisture, vitamin A, vitamin C, calcium, sodium, iron, and ash. E. coli and general bacteria were not detected at all, but stored at room temperature for more than one month, indicating that the purified wood vinegar itself has a function of inhibiting bacterial growth.

In addition, the cells age because the generation of oxygen, which is a kind of active oxygen, is excessive in the cells. The function of regulating free radicals in the body is responsible for an enzyme called SOD, which is degraded when excessive free radicals accumulate.

Free radicals finally become oxides, causing cells to die. However, wood vinegar is excellent in the ability to remove free radicals in the cell (SOD function) to remove foreign substances in the cell, normalize the respiratory circuit of the cell, and to healthy cells and protect the skin from various harmful environments.

And because the wood vinegar emits a lot of far infrared rays, dilution with water makes the molecular group of water very dense. Generally, the molecular group of water is about 146㎐, and it diminishes to about 54㎐ even after diluting 1,000 times of wood vinegar.

Molecular groups of water are termed clusters. When this value decreases, it dissolves much oxygen. When the oxygen is dissolved and bathed in water with a small molecular group of water, the skin becomes smooth, and it is also effective in skin diseases such as beauty and atopic dermatitis, and coldness. Therefore, in the present invention, the wood vinegar is included as an essential ingredient.

In the present invention, in addition to the above components, atopic dermatitis, the herbal ingredients for lowering the heat, the herbal ingredients for treating the damaged area and the herbal ingredients for stopping the pain and to relieve pain.

According to the present invention, the herb ingredients for lowering heat to the affected area where atopy is generated include changja, ringworm and sesame as essential ingredients, and herbal medicines such as ginseng and / or casualties may be selectively used.

Changthiza (Xthium strumarium L.) is one of the most commonly used folk medicinal herbs for the use of the seed of the lizard. The seeds are called Changyi, Shiisil, Hosil, Jigyu, Seal, Firm, etc., and have long been known as drugs for leprosy, sinusitis, rhinitis, arthritis. Imports from China have little effect, and they are only effective when they are from our country.

Because of the high content of iodine in docomari, it is also used for hypothyroidism, arthritis, leprosy and malignant tumors. Insects parasitic on stems also have effects on boils and spears. The most common and rare medicine is dokmari. Changza's main components include 1.2% xanthostrumarin, 3.3% resin, and fatty oils, alkaloids, and vitamin C.

Changjaza's main effect is bacteriostatic action against Staphylococcus aureus and is used for typhoons, flatulence, itching, scabies and head winds. When sinusitis is clogged nose and head hurts, it also works to relieve inflammation such as runny nose and itching of the skin.

Dictamnus dsycarpus Turez is a perennial herb that grows about 50-100 cm. It grows in the low hills of various parts of the country, with white or pink flowers in summer. Sheep smelling from this plant is known as ringworm and baekyangseon.

In the autumn, digging roots, washing with water, peeled and dried. Ingredients include 0.13% alkaloids in the roots, 0.02% to 0.03% in the root bark, dichtamins, tricholinin, choline, dictamnolactone, proxinelone, dictamnolide, and obaku. Paddy, saponin, camphorsterol, cytosterol, essential oils and the like.

It is known as an important medicine used for quadriplegic anxiety in oriental medicine, and it is used as a parasitic medicine, and it is a fever lowering medicine, analgesic medicine, acupuncture medicine, analgesic medicine, sedative medicine, etc. Used as a diuretic.

They also apply rooting medicine to eczema, filamentous skin disease, thyroid, swelling, pus, whaling, scabies, hives, baldness and various flower buds. In the private sector, the seeds are taken to cough and throat Qatar, and the outpost is used as a sputum medicine. The outpost decoction has a therapeutic effect on athlete's foot, but fresh outpost causes dermatitis.

Seontae is naked when cicada is transformed, and it is used for urticaria and gust wind due to its high temper.

According to the present invention, the lanceolate, ringworm skin and sunscreen are extracted from the active ingredient in the presence of an oil-soluble solvent such as oil, alcohol or glycol (hereinafter also referred to as "first herbal extract"). Since the active ingredients are fat-soluble, water is not preferable as a solvent. The amount of the solvent is preferably about 1 to 20 times by weight, but is not particularly limited thereto.

The mixing ratio of the first herbal extract is Changjiza 10-50% by weight, 20-60% by weight of ringworm skin and 10-50% by weight of the selection can reduce atopic dermatitis, ie wounds and heat of the body is preferable, Outside the range tends to reduce the effect of lowering the wound and body heat.

According to the present invention, 1 to 15% by weight of wood vinegar is mixed with 1 to 20% by weight of the first herbal extract to obtain an external preparation (hereinafter referred to as "first external preparation"). In the first external preparation, the remaining ingredients are other excipients constituting the cosmetic component. These are well known to those skilled in the art and to the art.

In the present invention, when the amount of the first herbal extract is less than 1% by weight, there is almost no effect of addition, and when it exceeds 20% by weight, there is a tendency to be accompanied by stimulation, and when the amount of wood vinegar is less than 1% by weight, the effect of addition Is almost absent, and if it exceeds 15% by weight, the phases tend to separate.

In addition, the first herbal extract may further include ginseng and / or casualties when the affected area is very severe.

Ginseng (Sophora angustifolia SIEB. Et Zucc) is a perennial herb, a perennial herb that grows to 1m in height when grown. Its leaf shape is similar to painting trees (lumps), so it has nicknames of lumps, lumps and wild lumps. The roots are washed and dried in autumn, and the taste is bitter, but it is called ginseng because it has the same effect as ginseng.

In oriental medicine, ginseng is used as a placebo, diuretic, antipyretic, analgesic, insecticide, jaundice, difficulty urination, scabies, eczema, dry ringworm. In addition, astringent hemostatic action is a long ton is a good tonic medicine. It is used as a palliative and phlegm for bronchitis and pulmonary tuberculosis, and as a respiratory stimulant. When treating malignant tumors, it is used as a decoction, jaundice, fever, and stroke. It is also used for headaches, rheumatism and sinusitis.

Casualties (Torilis japonica (HOUTT) DC.) Is an annual herb belonging to the Buttercup family, which is a fruit of the bee venom and the same plant. Efficacy is written in medicine such as abdominal pain, tetanus, sweating, bone pain, vegetable poisoning, yin and yang, toothache, quality, stool, leukoplakia, fever, low back pain, seawater, uterus, arthritis, prolapse. There are also antifungal, hookworm and sex hormone-like effects.

On the other hand, according to the present invention, as an herbal medicine for the purpose of healing the damaged site can be used Angelica, sage and selection.

Dongguk is a word that comes from the root of Shingamchae, which is excellent in blood and is used for gynecological diseases. Licorice is the root of wearyness, and its temper is cold, mild to urine, and used for swelling, swelling, or general swelling.

According to the present invention, the Angelica sinensis, soybean and sunscreen are extracted from the active ingredient in the presence of a fat-soluble solvent such as oil, alcohol or glycol (hereinafter also referred to as "second herbal extract"). Since the active ingredients are fat-soluble, water is not preferable as a solvent. The amount of the solvent is preferably about 1 to 20 times by weight as in the first herbal extract, but is not particularly limited thereto.

The mixing ratio of the second herb extract is preferably 20 to 60% by weight, 10 to 50% by weight and 10% to 50% by weight of the selection can heal the damaged area of the atopic dermatitis. Healing tends to be less effective.

According to the present invention, 1 to 20% by weight of the second herbal extract, 1 to 15% by weight of ceramide and 1 to 15% by weight of wood vinegar are mixed to obtain an external preparation (hereinafter referred to as "second external preparation"). In the second external preparation, the remaining ingredients are other excipients constituting the cosmetic component. These are well known to those skilled in the art and to the art.

In the present invention, when the amount of the second herbal extract is less than 1% by weight, there is almost no effect of addition, and 20% by weight tends to accompany skin irritation, and when the amount of ceramide added is less than 1% by weight, the effect of addition is There is almost no, and when it exceeds 15% by weight, it tends to fly like a powder. In addition, when the amount of the wood vinegar added is less than 1% by weight, there is almost no effect of addition, and when it exceeds 15% by weight, the phases tend to separate.

Finally, the herb ingredient that protects the damaged area and prevents damage can be used platinum, jeonjeonji and white paper.

The weight is the root of the overgrown (紫 蘭) in one shot, so that the blood swelling is mainly applied to the trauma or stomach ulcers. The former is used to facilitate blood circulation. White paper is the root of the billet, used for colds such as headaches, back pain, and discontinuity.

According to the present invention, the white, former and white paper is pulverized and used in powder form. The mixing ratio of the herbal powder is preferred in terms of the effect of protecting the damaged area 10-100% by weight, 10-40% by weight and 10-40% by weight of white paper, in particular, since it is in the form of powder It can prevent damage. The herbal powder may further comprise other excipients well known to those skilled in the art and the art.

In addition, the herbal powder may further include ringworm skin and / or white sewage when the affected part is severe. The ringworm is a horse that reaches the ring of the ringworm roots in one shot, the nature is cold and bitter and writes on jaundice and skin diseases. Baek Ha Shou is the root of Park Ju-Kari, used as a tonic medicine.

The cosmetic composition of the present invention thus configured may be in the form of a cream, lotion, essence, skin, powder, foundation, sun cream, body lotion or body cleanser.

On the other hand, according to the present invention, the first external agent is first applied to the atopic lesion to lower the heat of the wound site and the body, and then applying the second external agent can easily heal the damaged area. In addition, by applying the Chinese medicine powder consisting of platinum, jeonjeonji and white paper on the affected area can protect the affected area when the first and second external preparations come into contact with foreign substances (eg clothes, people, etc.), and also increase the therapeutic effect have.

Hereinafter, the present invention will be described in more detail with reference to the following examples. However, the following examples are not intended to limit the scope of the present invention.

Example 1-1

Preparation of the first external preparation

After preparing 480 g of red ginseng, 120 g of Changjaza, 160 g of ringworm skin and 120 g of casualty, 3 l of olive oil is heated to 140 ° C. After heating, mix red ginseng, changja and ringworm, and continue to get wet for 2 hours. At this time, the temperature of the olive oil continues to maintain 140 ℃. After the above process, stop heating, add 120 g of casualties and wet for 5 minutes. At the last step, 200 g of selection is added and wet well for 1 hour (first herbal extract). The first herbal extract is filtered through a filter paper, and then paraffin wax for cosmetics and wood vinegar 20g are put in a container and gelled.

Example 1-2

In Example 1-1, the solvent was extracted with ethanol, and then the extract was diluted in a ratio of 50: 50 using 1,3-butylene glycol, and then 10 wt% was used in the following cosmetic composition formulation (Table 1). do.

ingredient Content (% by weight) First Herbal Medicine Extract 10.0 Sodium Ethylenediaminetetraacetate 0.02 Allantoin 0.1 glycerin 5.0 Methyl paraoxybenzoate 0.2 Sodium Hyaluronic Acid 6.0 Carbomer 0.1-1.0 Cetostearyl alcohol 1.7-3.0 Polydecene 2.0 to 4.0 Squalane 2.0 Paraoxybenzoic acid propyl 0.1 Butylene Glycol Dicaprylate / Dicaprylate 3.0 Cetyloctanoate 5.0 Microcrystalline Lead 0.1 to 2.0 Trimethylpentanediol / adipic acid copolymer 0.1 Shea Butter 0.2-2.0 Sorbitan oleate 0.3 Cyclomethicone 0.3 Stearyl Dimethicone 0.5 Polyacrylamide / C13-14 Isoparaffin / Laureth-7 0.55 Triethanolamine 0.2 Imidazolidinylurea 0.3 Spices Suitable amount Wood vinegar 5.0 Purified water Applied at 100%

Example 2-1

Preparation of Second External Solvent

After preparing the Angelica 300g, 200g of licorice, 1.6l of olive oil (Olive Oil) is heated to about 140 ℃. After heating, stir in small portions over two hours. At this time, the temperature of the olive oil continues to maintain 140 ℃. After finishing the above process, stop heating, add 200 g of Korean vinegar and wet for 5 minutes. At the end of the process add 200g of choice and wet well for 1 hour. After filtering the solution, 5 wt% of the ceramide raw material is added and wet well (second herbal extract). Paraffin wax for cosmetics and wood vinegar solution 10g is added to the second herbal extract, and put in a container to gel.

Example 2-2

After extracting the solvent in Example 2-1 with ethanol, the extract was diluted in a ratio of 50:50 using 1,3-BG, and then 10% by weight is used in the following cosmetic composition formulation (Table 2).

ingredient Content (% by weight) Second Herbal Medicine Extract 10.0 Sodium Ethylenediaminetetraacetate 0.02 Allantoin 0.1 glycerin 5.0 Methyl paraoxybenzoate 0.2 Sodium Hyaluronic Acid 6.0 Carbomer 0.1-1.0 Cetostearyl alcohol 1.7-3.0 Polydecene 2.0 to 4.0 Squalane 2.0 Paraoxybenzoic acid propyl 0.1 Butylene Glycol Dicaprylate / Dicaprylate 3.0 Cetyloctanoate 5.0 Microcrystalline Lead 0.1 to 2.0 Trimethylpentanediol / adipic acid copolymer 0.1 Shea Butter 0.2-2.0 Sorbitan oleate 0.3 Cyclomethicone 0.3 Stearyl Dimethicone 0.5 Polyacrylamide / C13-14 Isoparaffin / Laureth-7 0.55 Triethanolamine 0.2 Imidazolidinylurea 0.3 Spices Suitable amount Wood vinegar 5.0 Ceramide 5.0 Purified water Applied at 100%

Example 3

Preparation of Chinese Medicine Powder

Grind the powder of 100g, Jeon, white paper, ringworm, white sewage, gypsum and activity into fine powder 200g, and then add 1.0g of tocopherol, 5.0g of ceramide, and 10g of zinc carbonate, and mix and grind for 1 minute with an atomizer.

The first external preparation, the second external preparation, and the herbal powder according to Examples 1 to 3 were used in 156 patients with atopic dermatitis. In the method of use, the first external preparation was applied to the affected area three times a day (morning, lunch and dinner), then the second external preparation was applied, and the herbal powder was sequentially applied to the affected area. The result is as follows.

Skin soothing and itching stops: 61.1%

2. Stop itching: 20.9%

3. Stop itching slightly: 10.2%

4. No change at all: 7.8%

As can be seen from the above results, it was confirmed that 92.2% of patients actually have an effect on skin soothing and atopic dermatitis. In addition, the same clinical results showed that the improvement rate of the dull skin was 89.9% and the effect on sensitive skin was 90.1%.

Atopic dermatitis patients in clinical trials were not itchy, no complaints and irritations, no side effects or recurrences, like steroids, but continued dietary care, but without eating as much as before, tingling and itching stress completely disappeared .

Claims (8)

Changsha, 35% by weight of the first external preparation comprising 1-20% by weight of the first herbal extract consisting of ringworm skin and sundae and 1-15% by weight of vinegar solution; 35% by weight of the second external preparation comprising 1-20% by weight of the second herb extract composed of Angelica, Korean herb and sundae, 1-15% by weight of ceramide and 1-15% by weight of vinegar solution; And 30% by weight of the Chinese medicine powder consisting of white, antipasti and white paper; Cosmetic composition having atopic dermatitis improvement, characterized in that consisting of. The method according to claim 1, The first herbal extract is a cosmetic composition having the ability to improve atopic dermatitis, characterized in that extracted by heating a herbal medicine consisting of 10 to 50% by weight, 20 to 60% by weight and whitening skin 10 to 50% by weight in the presence of a solvent . The method according to claim 1, The second herbal extract is a cosmetic composition having the ability to improve atopic dermatitis, characterized in that extracted by heating a herbal medicine consisting of 20 to 60% by weight, 10 to 50% by weight and 10 to 50% by weight in the presence of a solvent. The method according to claim 1, The herbal powder is a cosmetic composition having atopic dermatitis improvement, characterized in that consisting of 10 to 40% by weight, 10 to 40% by weight and 10 to 40% by weight of white paper. The method according to claim 1, The first herbal extract is a cosmetic composition having the ability to improve atopic dermatitis, characterized in that it further comprises a ginseng, casualties or a mixture thereof. The method according to claim 1, The herbal powder is a cosmetic composition having atopic dermatitis improvement, characterized in that it further comprises ringworm, white sewage or a mixture thereof. The cosmetic composition according to any one of claims 1 to 6, wherein the composition is a cream, lotion, essence, skin, powder, foundation, sunscreen, body lotion or body cleanser. delete