KR101113003B1 - 추진제로 하이드로-플루오로-알칸을 사용하는 계량 흡입기용 제형 - Google Patents

추진제로 하이드로-플루오로-알칸을 사용하는 계량 흡입기용 제형 Download PDF

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Publication number
KR101113003B1
KR101113003B1 KR1020057017414A KR20057017414A KR101113003B1 KR 101113003 B1 KR101113003 B1 KR 101113003B1 KR 1020057017414 A KR1020057017414 A KR 1020057017414A KR 20057017414 A KR20057017414 A KR 20057017414A KR 101113003 B1 KR101113003 B1 KR 101113003B1
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KR
South Korea
Prior art keywords
formulation
water
propellant
ethanol
hfa
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Expired - Fee Related
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KR1020057017414A
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English (en)
Korean (ko)
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KR20050111382A (ko
Inventor
조지 데스테파노
린다 진 켈라쉬-칸나보
Original Assignee
베링거 인겔하임 파마슈티칼즈, 인코포레이티드
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Publication of KR20050111382A publication Critical patent/KR20050111382A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
KR1020057017414A 2003-03-20 2004-03-19 추진제로 하이드로-플루오로-알칸을 사용하는 계량 흡입기용 제형 Expired - Fee Related KR101113003B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45611303P 2003-03-20 2003-03-20
US60/456,113 2003-03-20
PCT/US2004/008375 WO2004084858A2 (en) 2003-03-20 2004-03-19 Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants

Publications (2)

Publication Number Publication Date
KR20050111382A KR20050111382A (ko) 2005-11-24
KR101113003B1 true KR101113003B1 (ko) 2012-02-24

Family

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KR1020057017414A Expired - Fee Related KR101113003B1 (ko) 2003-03-20 2004-03-19 추진제로 하이드로-플루오로-알칸을 사용하는 계량 흡입기용 제형

Country Status (28)

Country Link
US (1) US7914770B2 (enExample)
EP (1) EP1608336B1 (enExample)
JP (1) JP4708332B2 (enExample)
KR (1) KR101113003B1 (enExample)
CN (1) CN1761455A (enExample)
AT (1) ATE390125T1 (enExample)
AU (1) AU2004224367B2 (enExample)
BR (1) BRPI0408547A (enExample)
CA (1) CA2519523C (enExample)
CO (1) CO5640070A2 (enExample)
CY (1) CY1108137T1 (enExample)
DE (1) DE602004012718T2 (enExample)
DK (1) DK1608336T3 (enExample)
EA (1) EA009087B1 (enExample)
EC (1) ECSP056029A (enExample)
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HR (1) HRP20050822B1 (enExample)
ME (1) ME00420B (enExample)
MX (1) MXPA05009920A (enExample)
NO (1) NO336457B1 (enExample)
NZ (1) NZ542957A (enExample)
PL (1) PL1608336T3 (enExample)
PT (1) PT1608336E (enExample)
RS (1) RS51663B (enExample)
SI (1) SI1608336T1 (enExample)
UA (1) UA89751C2 (enExample)
WO (1) WO2004084858A2 (enExample)
ZA (1) ZA200506463B (enExample)

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EA013428B1 (ru) * 2004-07-02 2010-04-30 Бёрингер Ингельхайм Интернациональ Гмбх РАСПЫЛЯЕМЫЕ В ВИДЕ АЭРОЗОЛЯ СУСПЕНЗИОННЫЕ КОМПОЗИЦИИ С TG 227ea ИЛИ TG 134a В КАЧЕСТВЕ ПРОПЕЛЛЕНТА
US20060140873A1 (en) * 2004-12-27 2006-06-29 Chang Heng W Aerosol pharmaceutical compositions
GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
GB0518769D0 (en) * 2005-09-14 2005-10-19 Medpharm Ltd Topical formulations
DE102006053374A1 (de) * 2006-02-09 2007-08-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz
DE102006014433A1 (de) 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen
DE102006017320A1 (de) * 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
WO2008047239A2 (en) * 2006-09-21 2008-04-24 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
EP2187969A2 (en) * 2007-08-17 2010-05-26 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
WO2010019953A1 (en) 2008-08-15 2010-02-18 Arcion Therapeutics, Inc. High concentration local anesthetic formulations for treating non-neuropathic pain
EP2662472B1 (de) 2009-03-31 2019-02-27 Boehringer Ingelheim International Gmbh Verfahren zur Beschichtung einer Oberfläche eines Bauteils
JP5763053B2 (ja) 2009-05-18 2015-08-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アダプタ、吸入器具及びアトマイザ
CN102686260B (zh) 2009-11-25 2014-10-01 贝林格尔.英格海姆国际有限公司 喷雾器
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
US9943654B2 (en) 2010-06-24 2018-04-17 Boehringer Ingelheim International Gmbh Nebulizer
US20120204871A1 (en) * 2011-02-10 2012-08-16 Julio Cesar Vega Stable, non-corrosive formulations for pressurized metered dose inhalers
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
CN102798044B (zh) * 2012-08-02 2014-09-10 深圳市华星光电技术有限公司 侧入式背光模组
PL2835146T3 (pl) 2013-08-09 2021-04-06 Boehringer Ingelheim International Gmbh Nebulizator
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
AU2015257878B2 (en) 2014-05-07 2019-08-08 Boehringer Ingelheim International Gmbh Container, nebulizer and use
MX380824B (es) 2014-05-07 2025-03-12 Boehringer Ingelheim Int Nebulizador y recipiente.
PL3139984T3 (pl) 2014-05-07 2021-11-08 Boehringer Ingelheim International Gmbh Nebulizator
US20180071231A1 (en) * 2015-04-10 2018-03-15 3M Innovative Properties Company Formulation and aerosol canisters, inhalers, and the like containing the formulation
GB2573297A (en) * 2018-04-30 2019-11-06 Mexichem Fluor Sa De Cv Pharmaceutical composition
WO2021216779A1 (en) * 2020-04-21 2021-10-28 Amphastar Pharmaceuticals, Inc. Anti-viral pharmaceutical formulations administered via devices for lung targeted delivery

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000068171A (ko) * 1997-06-13 2000-11-25 파올로 키에시 에어로졸 약제성분
US6261539B1 (en) * 1998-12-10 2001-07-17 Akwete Adjei Medicinal aerosol formulation
KR100312357B1 (ko) * 1992-12-09 2002-04-24 데이비드 이. 프랭크하우저 안정화된약제의에어로졸용액제제

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US4405598A (en) * 1976-01-30 1983-09-20 Fisons, Limited Composition for treating asthma
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US5919435A (en) 1990-11-09 1999-07-06 Glaxo Group Limited Aerosol formulation containing a particulate medicament
GB9202519D0 (en) * 1992-02-06 1992-03-25 Glaxo Group Ltd Medicaments
DE69701051T2 (de) 1993-04-30 2000-08-31 Minnesota Mining And Mfg. Co., Saint Paul Abdichtung an Aerosolbehältern
ES2119219T5 (es) 1993-07-15 2011-05-11 Minnesota Mining And Manufacturing Company Cierres estancos para uso en un dispositivo para suministrar un aerosol.
GEP20002266B (en) * 1995-04-14 2000-10-25 Glaxo Wellcome Inc Metered Dose Inhaler, the Inhaler System Comprising the Same and Method for Treatment of Respiratory Disturbances
GB9513084D0 (en) 1995-06-27 1995-08-30 Bespak Plc Dispensing apparatus
SE9701750D0 (sv) 1997-05-12 1997-05-12 Astra Pharma Prod Inhalation device and method of manufacture thereof
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US6423298B2 (en) * 1998-06-18 2002-07-23 Boehringer Ingelheim Pharmaceuticals, Inc. Pharmaceutical formulations for aerosols with two or more active substances
DE59904648D1 (de) * 1998-08-04 2003-04-24 Jago Res Ag Muttenz Medizinische aerosolformulierungen
IT1303788B1 (it) 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US7074388B2 (en) * 1998-12-10 2006-07-11 Kos Life Science, Inc. Water stabilized medicinal aerosol formulation
US20030008369A1 (en) * 1999-03-03 2003-01-09 Board Of Regents, The University Of Texas System Genetic and epigenetic manipulation of ABC transporters and ecto-phosphatases
GB0002798D0 (en) 2000-02-09 2000-03-29 Glaxo Group Ltd Actuator nozzle for metered dose inhaler
EP1241113A1 (en) 2001-03-12 2002-09-18 CHIESI FARMACEUTICI S.p.A. Inhaler with means for improving chemical stability of medicinal aerosol solution contained therein
CA2452140C (en) 2001-06-26 2010-12-14 Norton Healthcare, Ltd. An improved aerosol actuator

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KR100312357B1 (ko) * 1992-12-09 2002-04-24 데이비드 이. 프랭크하우저 안정화된약제의에어로졸용액제제
KR20000068171A (ko) * 1997-06-13 2000-11-25 파올로 키에시 에어로졸 약제성분
US6261539B1 (en) * 1998-12-10 2001-07-17 Akwete Adjei Medicinal aerosol formulation

Also Published As

Publication number Publication date
JP4708332B2 (ja) 2011-06-22
PL1608336T3 (pl) 2008-09-30
PT1608336E (pt) 2008-04-21
ME00420B (me) 2011-12-20
DE602004012718T2 (de) 2009-05-07
JP2006520797A (ja) 2006-09-14
AU2004224367A1 (en) 2004-10-07
ATE390125T1 (de) 2008-04-15
BRPI0408547A (pt) 2006-03-07
ES2304616T3 (es) 2008-10-16
NZ542957A (en) 2008-09-26
CA2519523A1 (en) 2004-10-07
US20040184994A1 (en) 2004-09-23
DE602004012718D1 (de) 2008-05-08
EA200501363A1 (ru) 2006-04-28
HRP20050822A2 (en) 2006-10-31
EA009087B1 (ru) 2007-10-26
SI1608336T1 (sl) 2008-08-31
ECSP056029A (es) 2006-01-27
ZA200506463B (en) 2006-04-26
WO2004084858A2 (en) 2004-10-07
AU2004224367B2 (en) 2009-10-08
MXPA05009920A (es) 2005-11-04
RS51663B (sr) 2011-10-31
DK1608336T3 (da) 2008-06-02
WO2004084858A3 (en) 2004-11-04
US7914770B2 (en) 2011-03-29
CA2519523C (en) 2012-03-13
UA89751C2 (ru) 2010-03-10
EP1608336B1 (en) 2008-03-26
HRP20050822B1 (hr) 2013-09-30
CO5640070A2 (es) 2006-05-31
RS20050705A (sr) 2008-04-04
CN1761455A (zh) 2006-04-19
CY1108137T1 (el) 2014-02-12
KR20050111382A (ko) 2005-11-24
EP1608336A2 (en) 2005-12-28
NO336457B1 (no) 2015-08-31
NO20054839L (no) 2005-10-19

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