KR101109500B1 - 4″- 또는 4′-위치에 알콕시메틸 치환체를 갖는 아버멕틴ｂ1 및 아버멕틴 ｂ1 모노사카라이드 유도체 - Google Patents

4″- 또는 4′-위치에 알콕시메틸 치환체를 갖는 아버멕틴ｂ1 및 아버멕틴 ｂ1 모노사카라이드 유도체 Download PDF

Info

Publication number
KR101109500B1
KR101109500B1 KR1020057011622A KR20057011622A KR101109500B1 KR 101109500 B1 KR101109500 B1 KR 101109500B1 KR 1020057011622 A KR1020057011622 A KR 1020057011622A KR 20057011622 A KR20057011622 A KR 20057011622A KR 101109500 B1 KR101109500 B1 KR 101109500B1
Authority
KR
South Korea
Prior art keywords
spp
alkyl
compound
formula
heterocyclyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020057011622A
Other languages
English (en)
Korean (ko)
Other versions
KR20050088133A (ko
Inventor
페터 마인피슈
케사비 피오나 머피
제롬 까사이르
라우라 콰란타
토마스 피테르나
오트마르 프란츠 휘터
피에르 정
Original Assignee
신젠타 파티서페이션즈 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 신젠타 파티서페이션즈 아게 filed Critical 신젠타 파티서페이션즈 아게
Publication of KR20050088133A publication Critical patent/KR20050088133A/ko
Application granted granted Critical
Publication of KR101109500B1 publication Critical patent/KR101109500B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020057011622A 2002-12-20 2003-12-19 4″- 또는 4′-위치에 알콕시메틸 치환체를 갖는 아버멕틴ｂ1 및 아버멕틴 ｂ1 모노사카라이드 유도체 Expired - Fee Related KR101109500B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0229804.0 2002-12-20
GBGB0229804.0A GB0229804D0 (en) 2002-12-20 2002-12-20 Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position
PCT/EP2003/014613 WO2004056844A1 (en) 2002-12-20 2003-12-19 Avermectin b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4”- or 4’-position

Publications (2)

Publication Number Publication Date
KR20050088133A KR20050088133A (ko) 2005-09-01
KR101109500B1 true KR101109500B1 (ko) 2012-01-31

Family

ID=9950151

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057011622A Expired - Fee Related KR101109500B1 (ko) 2002-12-20 2003-12-19 4″- 또는 4′-위치에 알콕시메틸 치환체를 갖는 아버멕틴ｂ1 및 아버멕틴 ｂ1 모노사카라이드 유도체

Country Status (22)

Country Link
US (3) US7737261B2 (https=)
EP (1) EP1581546B1 (https=)
JP (2) JP4851094B2 (https=)
KR (1) KR101109500B1 (https=)
CN (1) CN1738828B (https=)
AR (1) AR042533A1 (https=)
AU (1) AU2003302284B2 (https=)
BR (1) BR0317601A (https=)
CA (1) CA2507774C (https=)
CO (1) CO5690647A1 (https=)
ES (1) ES2742899T3 (https=)
GB (1) GB0229804D0 (https=)
IL (1) IL169092A (https=)
MA (1) MA27646A1 (https=)
MX (1) MXPA05006036A (https=)
PE (1) PE20040713A1 (https=)
PL (1) PL211483B1 (https=)
RU (1) RU2330857C2 (https=)
TW (1) TW200512214A (https=)
UA (1) UA81281C2 (https=)
WO (1) WO2004056844A1 (https=)
ZA (1) ZA200504353B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0229804D0 (en) * 2002-12-20 2003-01-29 Syngenta Participations Ag Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position
JP2010006703A (ja) * 2006-11-07 2010-01-14 Hokko Chem Ind Co Ltd アベルメクチンモノ配糖体誘導体
RU2453553C1 (ru) * 2011-05-11 2012-06-20 Игорь Викторович Заварзин 5-о-сукциноилавермектин, способ его получения и антипаразитарное средство на его основе
RU2472801C1 (ru) * 2011-05-11 2013-01-20 Игорь Викторович Заварзин 5-о-производные авермектина, способ их получения и антипаразитарные средства на их основе
CN103613625B (zh) * 2013-12-02 2016-03-02 兰州大学 一种阿维菌素类化合物及其制备方法和在农药中的用途
CN104402953B (zh) * 2014-11-28 2017-07-28 大庆志飞生物化工有限公司 阿维菌素单糖化合物及其制备方法和用途
CN104402954A (zh) * 2014-11-28 2015-03-11 大庆志飞生物化工有限公司 甲胺基阿维菌素单糖化合物及其制备方法和用途
JP6577184B2 (ja) 2014-12-24 2019-09-18 Ntn株式会社 転がり軸受
CN107501368B (zh) * 2017-09-30 2020-02-21 中国科学院成都生物研究所 一种多拉菌素衍生物的合成及其杀虫应用
CN113150053B (zh) * 2020-01-22 2024-10-01 华东理工大学 偶氮苯类阿维菌素衍生物及其制备方法和应用
CN113817008B (zh) * 2021-07-15 2023-05-23 湖州师范学院 新型琥珀酰基十六元大环内酯的制备方法及用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050169839A1 (en) * 2002-03-05 2005-08-04 Fong Tung M. Biomarker for efficacy of appetite suppressant drugs

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US87519A (en) * 1869-03-02 Improvement in furnace-stoves and registers
US18993A (en) * 1857-12-29 Cider-mill
US148520A (en) * 1874-03-10 Improvement in faucets
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4874749A (en) * 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
GB8811037D0 (en) 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
EP0353959A2 (en) 1988-08-02 1990-02-07 Beecham Group Plc Antihelmintic macrolide antibiotics
SE465605B (sv) * 1990-02-26 1991-10-07 Harry Nilsson Skivfilter
JP2622197B2 (ja) 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
US5169839A (en) * 1990-05-11 1992-12-08 Merck & Co., Inc. Derivatives of 3'- and 3"-o-desmethyl avermectin compounds, compositions and methods of treating melmintic and parasitic infections
US5262400A (en) * 1991-06-20 1993-11-16 Merck & Co., Inc. 4α-substituted avermectin derivatives
US5411737A (en) 1991-10-15 1995-05-02 Merck & Co., Inc. Slow release syneresing polymeric drug delivery device
US5602107A (en) 1993-05-10 1997-02-11 Merck & Co., Inc. Pour-on formulations consisting of gylcols, glycerides and avermectin compounds
PL174488B1 (pl) 1993-05-10 1998-08-31 Merck & Co Inc Preparat do zwalczania pasożytów zwierząt oraz sposób wytwarzania preparatu do zwalczania pasożytów zwierząt
CA2168843C (en) * 1993-08-19 2004-10-19 Raymond Cvetovich Thermodynamically stable crystal form of 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b benzoic acid salt and processes for its preparation
US5436355A (en) 1994-02-03 1995-07-25 Merck & Co., Inc. Process for making avermectin/zein compositions
TW327125B (en) 1994-02-07 1998-02-21 Merck & Co Inc Composition and method for protecting against pine exhausted
WO2002012248A1 (en) 2000-08-09 2002-02-14 The Kitasato Institute Avermectin derivatives
JPWO2002012261A1 (ja) 2000-08-09 2004-01-15 社団法人北里研究所 エバーメクチン誘導体
GB0229804D0 (en) 2002-12-20 2003-01-29 Syngenta Participations Ag Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050169839A1 (en) * 2002-03-05 2005-08-04 Fong Tung M. Biomarker for efficacy of appetite suppressant drugs

Also Published As

Publication number Publication date
MA27646A1 (fr) 2005-12-01
US7737261B2 (en) 2010-06-15
IL169092A0 (en) 2007-07-04
IL169092A (en) 2010-12-30
AU2003302284B2 (en) 2009-07-23
US20100210574A1 (en) 2010-08-19
US8263566B2 (en) 2012-09-11
CA2507774C (en) 2011-06-14
RU2330857C2 (ru) 2008-08-10
WO2004056844A1 (en) 2004-07-08
PE20040713A1 (es) 2004-12-02
GB0229804D0 (en) 2003-01-29
PL377497A1 (pl) 2006-02-06
RU2005122943A (ru) 2006-01-20
JP2011102303A (ja) 2011-05-26
CN1738828A (zh) 2006-02-22
AU2003302284A1 (en) 2004-07-14
UA81281C2 (en) 2007-12-25
US20110230429A1 (en) 2011-09-22
US20060148729A1 (en) 2006-07-06
EP1581546A1 (en) 2005-10-05
CN1738828B (zh) 2012-09-05
JP4851094B2 (ja) 2012-01-11
JP5302297B2 (ja) 2013-10-02
CA2507774A1 (en) 2004-07-08
US8017589B2 (en) 2011-09-13
TW200512214A (en) 2005-04-01
AR042533A1 (es) 2005-06-22
EP1581546B1 (en) 2019-03-20
ZA200504353B (en) 2006-03-29
JP2006515849A (ja) 2006-06-08
KR20050088133A (ko) 2005-09-01
PL211483B1 (pl) 2012-05-31
CO5690647A1 (es) 2006-10-31
ES2742899T3 (es) 2020-02-17
MXPA05006036A (es) 2005-08-18
BR0317601A (pt) 2005-11-29

Similar Documents

Publication Publication Date Title
US8263566B2 (en) Avermectin B1 and avermectin B1 monosaccharide derivatives having an alkoxymethyl substituent in the 4″-or 4′-position
EP1594878B1 (en) Avermectin monosaccharide derivatives having pesticidal properties
EP1613639B1 (en) Avermectins substituted in the 4'' and 4´-positions having pesticidal properties
US7632820B2 (en) Avermectin and avemectin monosaccharide derivatives substituted in the 4″- or 4′-position having pesticidal properties
EP1660510B1 (en) Avermectins and avermectin monosaccharides substituted in the 4'- and 4'' position having pesticidal properties
EP1638984B1 (en) Avermectin b1 monosaccharide derivatives
US20060094600A1 (en) Avermectins and avermectin monosaccharides substituted in the 4'-and 4"-position having pesticidal properties

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

FPAY Annual fee payment

Payment date: 20150106

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

FPAY Annual fee payment

Payment date: 20160108

Year of fee payment: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000

FPAY Annual fee payment

Payment date: 20170111

Year of fee payment: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

FPAY Annual fee payment

Payment date: 20180105

Year of fee payment: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000

FPAY Annual fee payment

Payment date: 20190108

Year of fee payment: 8

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 9

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 10

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20220119

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20220119