KR101090529B1 - 면역약화된 집단에 사용하기 위한 당결합체 백신 - Google Patents

면역약화된 집단에 사용하기 위한 당결합체 백신 Download PDF

Info

Publication number
KR101090529B1
KR101090529B1 KR1020087022908A KR20087022908A KR101090529B1 KR 101090529 B1 KR101090529 B1 KR 101090529B1 KR 1020087022908 A KR1020087022908 A KR 1020087022908A KR 20087022908 A KR20087022908 A KR 20087022908A KR 101090529 B1 KR101090529 B1 KR 101090529B1
Authority
KR
South Korea
Prior art keywords
vaccine
patients
staphylococcus aureus
type
staphylococcus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1020087022908A
Other languages
English (en)
Korean (ko)
Other versions
KR20080089527A (ko
Inventor
알리 아이. 파톰
로버트 비. 나소
Original Assignee
글락소스미스클라인 바이오로지칼즈 에스.에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 글락소스미스클라인 바이오로지칼즈 에스.에이. filed Critical 글락소스미스클라인 바이오로지칼즈 에스.에이.
Publication of KR20080089527A publication Critical patent/KR20080089527A/ko
Application granted granted Critical
Publication of KR101090529B1 publication Critical patent/KR101090529B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/116Polyvalent bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
KR1020087022908A 2001-09-19 2002-09-19 면역약화된 집단에 사용하기 위한 당결합체 백신 Expired - Lifetime KR101090529B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/955,585 US20030113350A1 (en) 2001-09-19 2001-09-19 Glycoconjugate vaccines for use in immune-compromised populations
US09/955,585 2001-09-19

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR10-2004-7003967A Division KR20040070331A (ko) 2001-09-19 2002-09-19 면역약화된 집단에 사용하기 위한 당결합체 백신

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020107005839A Division KR101214766B1 (ko) 2001-09-19 2002-09-19 면역약화된 집단에 사용하기 위한 당결합체 백신

Publications (2)

Publication Number Publication Date
KR20080089527A KR20080089527A (ko) 2008-10-06
KR101090529B1 true KR101090529B1 (ko) 2011-12-08

Family

ID=25497036

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1020087022908A Expired - Lifetime KR101090529B1 (ko) 2001-09-19 2002-09-19 면역약화된 집단에 사용하기 위한 당결합체 백신
KR10-2004-7003967A Ceased KR20040070331A (ko) 2001-09-19 2002-09-19 면역약화된 집단에 사용하기 위한 당결합체 백신
KR1020107005839A Expired - Lifetime KR101214766B1 (ko) 2001-09-19 2002-09-19 면역약화된 집단에 사용하기 위한 당결합체 백신

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR10-2004-7003967A Ceased KR20040070331A (ko) 2001-09-19 2002-09-19 면역약화된 집단에 사용하기 위한 당결합체 백신
KR1020107005839A Expired - Lifetime KR101214766B1 (ko) 2001-09-19 2002-09-19 면역약화된 집단에 사용하기 위한 당결합체 백신

Country Status (11)

Country Link
US (2) US20030113350A1 (enExample)
EP (1) EP1427442A4 (enExample)
JP (2) JP2005515237A (enExample)
KR (3) KR101090529B1 (enExample)
CN (1) CN1306958C (enExample)
CA (1) CA2460749C (enExample)
EA (1) EA006602B1 (enExample)
MX (1) MXPA04002624A (enExample)
NZ (1) NZ548453A (enExample)
WO (1) WO2003061558A2 (enExample)
ZA (1) ZA200402185B (enExample)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100217772B1 (ko) * 1996-09-03 1999-09-01 최진호 조명기기의 램프 과열방지 장치 및 방법
US20020092987A1 (en) * 1998-09-05 2002-07-18 Taehee Cho Photo detect device using quantum dots and materialization method thereof
US6936258B1 (en) * 1999-03-19 2005-08-30 Nabi Biopharmaceuticals Staphylococcus antigen and vaccine
PT1565478T (pt) 2002-11-12 2017-11-14 The Brigham And Women`S Hospital Inc Vacina de polissacáridos para infeções estafilocócicas
WO2004050846A2 (en) * 2002-12-02 2004-06-17 Biosynexus Incorporated Wall teichoic acid as a target for anti-staphylococcal therapies and vaccines
JP5102487B2 (ja) * 2003-03-07 2012-12-19 ワイス・ホールディングズ・コーポレイション 院内感染に対する免疫化のための多糖ブドウ球菌表面付着因子キャリアタンパク質接合体
AU2011265368B9 (en) * 2004-09-22 2012-11-29 Biosynexus Incorporated Immunogenic composition
RU2402347C2 (ru) * 2004-09-22 2010-10-27 ГлаксоСмитКлайн Байолоджикалз с.а. Иммуногенная композиция
US20060134141A1 (en) * 2004-12-14 2006-06-22 Nabi Biopharmaceuticals Glycoconjugate vaccines containing peptidoglycan
AU2005324448A1 (en) * 2005-01-10 2006-07-20 Glaxosmithkline Biologicals Sa Method of treating Staphylococcus aureus infection
US20060228368A1 (en) * 2005-04-07 2006-10-12 Nabi Biopharmaceuticals Method of protecting against staphylococcal infection
FR2884830A1 (fr) 2005-04-25 2006-10-27 Sanofi Pasteur Sa Procede de production de souches de staphylococcus aureus surproductrices
PL3006458T3 (pl) * 2005-07-29 2018-05-30 The Government Of The United States Of America, As Represented By The Secretary Of Health And Human Services Zmutowane egzotoksyny Pseudomonas o zmniejszonej antygenowości
WO2007113222A2 (en) * 2006-03-30 2007-10-11 Glaxosmithkline Biologicals S.A. Immunogenic composition
FR2899110A1 (fr) * 2006-03-31 2007-10-05 Sanofi Pasteur Sa Polysaccharides capsulaires de type 5 et de type 8 des souches surproductrices de staphylococcus aureus
GB0700136D0 (en) * 2007-01-04 2007-02-14 Glaxosmithkline Biolog Sa Process for manufacturing vaccines
US9181329B2 (en) 2007-08-31 2015-11-10 The University Of Chicago Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions
JP5658564B2 (ja) * 2007-08-31 2015-01-28 ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago ブドウ球菌肺疾患および状態に対する免疫に関連した方法および組成物
KR101573648B1 (ko) 2008-07-21 2015-12-01 더 브리검 앤드 우먼즈 하스피털, 인크. 합성 베타-1,6 글루코사민 올리고당에 관한 방법 및 조성물
WO2010014304A1 (en) * 2008-07-29 2010-02-04 University Of Chicago Compositions and methods related to staphylococcal bacterium proteins
HUE026855T2 (en) 2009-04-03 2016-07-28 Univ Chicago Compositions and methods related to protein a (spa) variants
WO2011041003A2 (en) 2009-06-22 2011-04-07 Wyeth Llc Compositions and methods for preparing staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions
SI2445522T1 (sl) 2009-06-22 2017-10-30 Wyeth Llc Imunogeni sestavki antigenov Staphylococcusa aureusa
GB0913681D0 (en) 2009-08-05 2009-09-16 Glaxosmithkline Biolog Sa Immunogenic composition
GB0913680D0 (en) 2009-08-05 2009-09-16 Glaxosmithkline Biolog Sa Immunogenic composition
MX373250B (es) 2009-09-30 2020-05-04 Glaxosmithkline Biologicals S A Star Conjugación de polisacáridos capsulares de tipo 5 y de tipo 8 de staphylococcus aureus.
BR112012010223A2 (pt) 2009-10-30 2016-12-06 Novartis Ag purificação de staphylococcus aureus tipo 5 e tipo 8 sacarídeos capsulares
AU2010342872B2 (en) * 2010-01-19 2014-09-25 Universitatsklinikum Freiburg Enterococcal cell wall components and antibacterial use thereof
SG186290A1 (en) 2010-07-02 2013-01-30 Univ Chicago Compositions and methods related to protein a (spa) variants
CN102565354A (zh) * 2010-12-13 2012-07-11 苏州艾杰生物科技有限公司 氨(氨离子)的测定方法与氨(氨离子)诊断/测定试剂盒
CN102539726A (zh) * 2010-12-13 2012-07-04 苏州艾杰生物科技有限公司 氨(氨离子)的测定方法与氨(氨离子)诊断/测定试剂盒
CN102539708A (zh) * 2010-12-13 2012-07-04 苏州艾杰生物科技有限公司 氨(氨离子)的测定方法与氨(氨离子)诊断/测定试剂盒
CN102539702A (zh) * 2010-12-13 2012-07-04 苏州艾杰生物科技有限公司 氨(氨离子)的测定方法与氨(氨离子)诊断/测定试剂盒
CN102565332A (zh) * 2010-12-13 2012-07-11 苏州艾杰生物科技有限公司 氨(氨离子)的测定方法与氨(氨离子)诊断/测定试剂盒
CN102565336A (zh) * 2010-12-13 2012-07-11 苏州艾杰生物科技有限公司 氨(氨离子)的测定方法与氨(氨离子)诊断/测定试剂盒
CN102539704A (zh) * 2010-12-13 2012-07-04 苏州艾杰生物科技有限公司 氨(氨离子)的测定方法与氨(氨离子)诊断/测定试剂盒
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
WO2014013375A1 (en) 2012-07-16 2014-01-23 Pfizer Inc. Saccharides and uses thereof
GB201310008D0 (en) 2013-06-05 2013-07-17 Glaxosmithkline Biolog Sa Immunogenic composition for use in therapy
WO2016091904A1 (en) 2014-12-10 2016-06-16 Glaxosmithkline Biologicals Sa Method of treatment
GB201721576D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa Hla antigens and glycoconjugates thereof
GB201721582D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa S aureus antigens and immunogenic compositions
US12397014B2 (en) 2019-02-05 2025-08-26 The Brigham And Women's Hospital, Inc. Polysaccharide compositions for use in treating filariasis
EP3777884A1 (en) 2019-08-15 2021-02-17 GlaxoSmithKline Biologicals S.A. Immunogenic composition
KR20220079534A (ko) * 2019-08-27 2022-06-13 알로펙스, 인크. 항미생물 백신 조성물
WO2023133143A1 (en) * 2022-01-05 2023-07-13 Bluewillow Biologics, Inc. Intranasal polysaccharide conjugate nanoemulsion vaccines and methods of using the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747024A (en) * 1993-03-08 1998-05-05 Immunex Corporation Vaccine adjuvant comprising interleukin-15
US5770208A (en) * 1996-09-11 1998-06-23 Nabi Staphylococcus aureus B-linked hexosamine antigen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Advances in Renal Replacement Therapy, Vol. 3, No. 4, pp. 302-308*

Also Published As

Publication number Publication date
WO2003061558A2 (en) 2003-07-31
CN1638794A (zh) 2005-07-13
ZA200402185B (en) 2005-06-29
KR101214766B1 (ko) 2012-12-24
CA2460749C (en) 2012-10-23
WO2003061558A3 (en) 2003-09-12
EA200400448A1 (ru) 2004-12-30
EP1427442A4 (en) 2006-06-21
WO2003061558A9 (en) 2004-06-10
US20030113350A1 (en) 2003-06-19
CA2460749A1 (en) 2003-07-31
KR20080089527A (ko) 2008-10-06
KR20040070331A (ko) 2004-08-07
US20060188518A1 (en) 2006-08-24
NZ548453A (en) 2007-07-27
CN1306958C (zh) 2007-03-28
EP1427442A2 (en) 2004-06-16
MXPA04002624A (es) 2005-02-17
JP2010265293A (ja) 2010-11-25
JP2005515237A (ja) 2005-05-26
US7449189B2 (en) 2008-11-11
KR20100044265A (ko) 2010-04-29
EA006602B1 (ru) 2006-02-24

Similar Documents

Publication Publication Date Title
KR101090529B1 (ko) 면역약화된 집단에 사용하기 위한 당결합체 백신
Brett et al. Structural and immunological characterization of Burkholderia pseudomallei O-polysaccharide-flagellin protein conjugates
AU2019215212B2 (en) Multivalent pneumococcal polysaccharide-protein conjugate composition
Wessels et al. Stimulation of protective antibodies against type Ia and Ib group B streptococci by a type Ia polysaccharide-tetanus toxoid conjugate vaccine
Austrian Pneumococcal polysaccharide vaccines
KR20180054629A (ko) 장외 병원성 e. 콜리에 대한 면역 보호를 위한 방법 및 조성물
KR20190055063A (ko) 다가 폐렴구균 다당류-단백질 접합체 조성물
CA2101648C (en) Polysaccharide-protein conjugates
Dintzis Rational design of conjugate vaccines
KR20190051945A (ko) 다가 폐렴구균 다당류-단백질 접합체 조성물
US20250352631A1 (en) Polyvalent pneumococcal polysaccharide conjugate vaccine component and application thereof
JPH08501563A (ja) グループbストレプトコッカス・タイプ▲ii▼およびタイプ▲v▼多糖−蛋白質接合ワクチン
Paoletti et al. Immunogenicity of group B Streptococcus type III polysaccharide-tetanus toxoid vaccine in baboons
AU2002365253B2 (en) Glycoconjugate vaccines for use in immune-compromised populations
Henriksen et al. Vaccination with Protein‐Conjugated and Native Type 3 Capsular Polysaccharide in an Ethanol‐Fed Rat Model of Pneumococcal Pneumonia
NZ531647A (en) Glycoconjugate vaccines for use in immune-compromised populations against Staphylococcal and Enterococcal infections
AU2002365253A1 (en) Glycoconjugate vaccines for use in immune-compromised populations
Naso et al. Polysaccharide conjugate vaccines for the prevention of gram-positive bacterial infections
Lee Capsule and vaccine development
HK40101369A (en) Methods and compositions for immune protection against extra-intestinal pathogenic e. coli
Byrd Development of conjugate vaccines to protect pigs against swine pleuropneumonia induced by Actinobacillus pleuropneumoniae
Gotschlich Immune response to the meningococcal group-specific polysaccharides
Fattom et al. Vaccines for Staphylococcus aureus infections

Legal Events

Date Code Title Description
A107 Divisional application of patent
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20080919

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20081020

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20081217

Patent event code: PE09021S01D

A107 Divisional application of patent
AMND Amendment
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20100316

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20100625

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20081217

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

N231 Notification of change of applicant
PN2301 Change of applicant

Patent event date: 20100830

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

Patent event date: 20100928

Comment text: Request for Trial against Decision on Refusal

Patent event code: PJ02012R01D

Patent event date: 20100625

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20110908

Appeal identifier: 2010101007457

Request date: 20100928

AMND Amendment
PB0901 Examination by re-examination before a trial

Comment text: Amendment to Specification, etc.

Patent event date: 20101028

Patent event code: PB09011R02I

Comment text: Request for Trial against Decision on Refusal

Patent event date: 20100928

Patent event code: PB09011R01I

Comment text: Amendment to Specification, etc.

Patent event date: 20100316

Patent event code: PB09011R02I

E90F Notification of reason for final refusal
PE0902 Notice of grounds for rejection

Comment text: Final Notice of Reason for Refusal

Patent event date: 20101129

Patent event code: PE09021S02D

B701 Decision to grant
PB0701 Decision of registration after re-examination before a trial

Patent event date: 20110908

Comment text: Decision to Grant Registration

Patent event code: PB07012S01D

Patent event date: 20101108

Comment text: Transfer of Trial File for Re-examination before a Trial

Patent event code: PB07011S01I

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20111130

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20111130

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
FPAY Annual fee payment

Payment date: 20141030

Year of fee payment: 4

PR1001 Payment of annual fee

Payment date: 20141030

Start annual number: 4

End annual number: 4

FPAY Annual fee payment

Payment date: 20150930

Year of fee payment: 5

PR1001 Payment of annual fee

Payment date: 20150930

Start annual number: 5

End annual number: 5

FPAY Annual fee payment

Payment date: 20161028

Year of fee payment: 6

PR1001 Payment of annual fee

Payment date: 20161028

Start annual number: 6

End annual number: 6

FPAY Annual fee payment

Payment date: 20170929

Year of fee payment: 7

PR1001 Payment of annual fee

Payment date: 20170929

Start annual number: 7

End annual number: 7

FPAY Annual fee payment

Payment date: 20180928

Year of fee payment: 8

PR1001 Payment of annual fee

Payment date: 20180928

Start annual number: 8

End annual number: 8

FPAY Annual fee payment

Payment date: 20190924

Year of fee payment: 9

PR1001 Payment of annual fee

Payment date: 20190924

Start annual number: 9

End annual number: 9

PR1001 Payment of annual fee

Payment date: 20211026

Start annual number: 11

End annual number: 11

PC1801 Expiration of term

Termination date: 20230319

Termination category: Expiration of duration