KR101073590B1 - Ｉｌ-13에 대한 인간 항체 분자 - Google Patents

Ｉｌ-13에 대한 인간 항체 분자 Download PDF

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Publication number
KR101073590B1
KR101073590B1 KR1020067000933A KR20067000933A KR101073590B1 KR 101073590 B1 KR101073590 B1 KR 101073590B1 KR 1020067000933 A KR1020067000933 A KR 1020067000933A KR 20067000933 A KR20067000933 A KR 20067000933A KR 101073590 B1 KR101073590 B1 KR 101073590B1
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South Korea
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ser
gly
seq
domain
antibody
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KR1020067000933A
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English (en)
Korean (ko)
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KR20060054312A (ko
Inventor
필립 데이빗 몽크
루츠 제르무투스
랄프 레이몬드 민터
셀리아 패트리시아 셜록
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메디뮨 리미티드
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Priority claimed from GBGB0407315.1A external-priority patent/GB0407315D0/en
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Publication of KR101073590B1 publication Critical patent/KR101073590B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020067000933A 2003-07-15 2004-07-15 Ｉｌ-13에 대한 인간 항체 분자 Expired - Lifetime KR101073590B1 (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US48751203P 2003-07-15 2003-07-15
US60/487,512 2003-07-15
US55821604P 2004-03-31 2004-03-31
US60/558,216 2004-03-31
GB0407315.1 2004-03-31
GBGB0407315.1A GB0407315D0 (en) 2003-07-15 2004-03-31 Human antibody molecules
US57379104P 2004-05-24 2004-05-24
US60/573,791 2004-05-24

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020117003966A Division KR101168815B1 (ko) 2003-07-15 2004-07-15 Ｉｌ-13에 대한 인간 항체 분자

Publications (2)

Publication Number Publication Date
KR20060054312A KR20060054312A (ko) 2006-05-22
KR101073590B1 true KR101073590B1 (ko) 2011-10-14

Family

ID=44535047

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067000933A Expired - Lifetime KR101073590B1 (ko) 2003-07-15 2004-07-15 Ｉｌ-13에 대한 인간 항체 분자

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Country Link
JP (3) JP5519567B2 (enrdf_load_stackoverflow)
KR (1) KR101073590B1 (enrdf_load_stackoverflow)
AU (1) AU2011200308B2 (enrdf_load_stackoverflow)
CY (1) CY1111467T1 (enrdf_load_stackoverflow)
HK (1) HK1216427A1 (enrdf_load_stackoverflow)
MX (1) MXPA06000258A (enrdf_load_stackoverflow)
NO (2) NO338853B1 (enrdf_load_stackoverflow)
RU (1) RU2009148270A (enrdf_load_stackoverflow)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201811177SA (en) * 2014-06-18 2019-01-30 Medimmune Llc Cell culture methods and media comprising n-acetylcysteine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003035847A2 (en) * 2001-10-26 2003-05-01 Centocor, Inc. Il-13 mutein proteins, antibodies, compositions, methods and uses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07508179A (ja) * 1992-08-21 1995-09-14 シェリング・コーポレーション ヒトインターロイキン−１３
ES2384100T3 (es) * 2001-12-03 2012-06-29 Alexion Pharmaceuticals, Inc. Método para producir anticuerpos híbridos
AU2003223497A1 (en) * 2002-04-05 2003-10-27 Centocor, Inc. Asthma-related anti-il-13 immunoglobulin derived proteins, compositions, methods and uses
EP1534323A2 (en) * 2002-08-30 2005-06-01 Glaxo Group Limited Il-14 vaccine for the treatment of asthma and atopic disorders
GB0407315D0 (en) * 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
TWI307630B (en) * 2004-07-01 2009-03-21 Glaxo Group Ltd Immunoglobulins

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003035847A2 (en) * 2001-10-26 2003-05-01 Centocor, Inc. Il-13 mutein proteins, antibodies, compositions, methods and uses

Also Published As

Publication number Publication date
JP5922686B2 (ja) 2016-05-24
NO338853B1 (no) 2016-10-24
JP2016047843A (ja) 2016-04-07
AU2011200308A1 (en) 2011-02-17
HK1216427A1 (zh) 2016-11-11
NO342727B1 (no) 2018-07-30
KR20060054312A (ko) 2006-05-22
AU2011200308B2 (en) 2011-07-28
CY1111467T1 (el) 2015-08-05
HK1097853A1 (en) 2007-07-06
RU2009148270A (ru) 2011-06-27
NO20160707A1 (no) 2016-04-27
JP2011147454A (ja) 2011-08-04
JP5519567B2 (ja) 2014-06-11
JP2014101372A (ja) 2014-06-05
NO20060730L (no) 2006-04-10
MXPA06000258A (es) 2006-07-03
HK1155185A1 (en) 2012-05-11

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