AU2011200308B2 - Human antibody molecules for IL-13 - Google Patents

Human antibody molecules for IL-13 Download PDF

Info

Publication number
AU2011200308B2
AU2011200308B2 AU2011200308A AU2011200308A AU2011200308B2 AU 2011200308 B2 AU2011200308 B2 AU 2011200308B2 AU 2011200308 A AU2011200308 A AU 2011200308A AU 2011200308 A AU2011200308 A AU 2011200308A AU 2011200308 B2 AU2011200308 B2 AU 2011200308B2
Authority
AU
Australia
Prior art keywords
domain
seq
antibody
human
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2011200308A
Other languages
English (en)
Other versions
AU2011200308A1 (en
Inventor
Lutz Jermutuz
Ralph Raymond Minter
Phillip David Monk
Celia Patricia Shorrock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MedImmune Ltd
Original Assignee
MedImmune Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0407315.1A external-priority patent/GB0407315D0/en
Application filed by MedImmune Ltd filed Critical MedImmune Ltd
Priority to AU2011200308A priority Critical patent/AU2011200308B2/en
Publication of AU2011200308A1 publication Critical patent/AU2011200308A1/en
Application granted granted Critical
Publication of AU2011200308B2 publication Critical patent/AU2011200308B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2011200308A 2003-07-15 2011-01-25 Human antibody molecules for IL-13 Expired AU2011200308B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2011200308A AU2011200308B2 (en) 2003-07-15 2011-01-25 Human antibody molecules for IL-13

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US48751203P 2003-07-15 2003-07-15
US60/487,512 2003-07-15
US55821604P 2004-03-31 2004-03-31
US60/558,216 2004-03-31
GB0407315.1 2004-03-31
GBGB0407315.1A GB0407315D0 (en) 2003-07-15 2004-03-31 Human antibody molecules
US57379104P 2004-05-24 2004-05-24
US60/573,791 2004-05-24
PCT/GB2004/003059 WO2005007699A2 (en) 2003-07-15 2004-07-15 Human antibody molecules for il-13
AU2004256976A AU2004256976B2 (en) 2003-07-15 2004-07-15 Human antibody molecules for IL-13
AU2011200308A AU2011200308B2 (en) 2003-07-15 2011-01-25 Human antibody molecules for IL-13

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU2004256976A Division AU2004256976B2 (en) 2003-07-15 2004-07-15 Human antibody molecules for IL-13

Publications (2)

Publication Number Publication Date
AU2011200308A1 AU2011200308A1 (en) 2011-02-17
AU2011200308B2 true AU2011200308B2 (en) 2011-07-28

Family

ID=44535047

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2011200308A Expired AU2011200308B2 (en) 2003-07-15 2011-01-25 Human antibody molecules for IL-13

Country Status (8)

Country Link
JP (3) JP5519567B2 (enrdf_load_stackoverflow)
KR (1) KR101073590B1 (enrdf_load_stackoverflow)
AU (1) AU2011200308B2 (enrdf_load_stackoverflow)
CY (1) CY1111467T1 (enrdf_load_stackoverflow)
HK (1) HK1216427A1 (enrdf_load_stackoverflow)
MX (1) MXPA06000258A (enrdf_load_stackoverflow)
NO (2) NO338853B1 (enrdf_load_stackoverflow)
RU (1) RU2009148270A (enrdf_load_stackoverflow)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201811177SA (en) * 2014-06-18 2019-01-30 Medimmune Llc Cell culture methods and media comprising n-acetylcysteine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07508179A (ja) * 1992-08-21 1995-09-14 シェリング・コーポレーション ヒトインターロイキン−13
JP2005512522A (ja) * 2001-10-26 2005-05-12 セントカー・インコーポレーテツド Il−13ムテインタンパク質、抗体、組成物、方法および使用
ES2384100T3 (es) * 2001-12-03 2012-06-29 Alexion Pharmaceuticals, Inc. Método para producir anticuerpos híbridos
AU2003223497A1 (en) * 2002-04-05 2003-10-27 Centocor, Inc. Asthma-related anti-il-13 immunoglobulin derived proteins, compositions, methods and uses
EP1534323A2 (en) * 2002-08-30 2005-06-01 Glaxo Group Limited Il-14 vaccine for the treatment of asthma and atopic disorders
GB0407315D0 (en) * 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
TWI307630B (en) * 2004-07-01 2009-03-21 Glaxo Group Ltd Immunoglobulins

Also Published As

Publication number Publication date
JP5922686B2 (ja) 2016-05-24
KR101073590B1 (ko) 2011-10-14
NO338853B1 (no) 2016-10-24
JP2016047843A (ja) 2016-04-07
AU2011200308A1 (en) 2011-02-17
HK1216427A1 (zh) 2016-11-11
NO342727B1 (no) 2018-07-30
KR20060054312A (ko) 2006-05-22
CY1111467T1 (el) 2015-08-05
HK1097853A1 (en) 2007-07-06
RU2009148270A (ru) 2011-06-27
NO20160707A1 (no) 2016-04-27
JP2011147454A (ja) 2011-08-04
JP5519567B2 (ja) 2014-06-11
JP2014101372A (ja) 2014-06-05
NO20060730L (no) 2006-04-10
MXPA06000258A (es) 2006-07-03
HK1155185A1 (en) 2012-05-11

Similar Documents

Publication Publication Date Title
US9856317B2 (en) Human antibody molecules for IL-13
MXPA06000240A (es) Dispositivo para la medicion de procesos de caudal volumetricos distribuidos en el tiempo.
AU2011200308B2 (en) Human antibody molecules for IL-13
HK1228920A (en) Neutralizing human antibody molecules for il-13
HK1228920A1 (en) Neutralizing human antibody molecules for il-13
HK1155185B (en) Human antibody molecules for il-13
HK1097853B (en) Human antibody molecules for il-13

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired