KR100817462B1 - 2-데하이드로-3-데옥시-d-글루코네이트로부터의2'-데옥시뉴클레오시드 및 2'-데옥시뉴클레오시드전구체들의 제조 - Google Patents

2-데하이드로-3-데옥시-d-글루코네이트로부터의2'-데옥시뉴클레오시드 및 2'-데옥시뉴클레오시드전구체들의 제조 Download PDF

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KR100817462B1
KR100817462B1 KR1020057024851A KR20057024851A KR100817462B1 KR 100817462 B1 KR100817462 B1 KR 100817462B1 KR 1020057024851 A KR1020057024851 A KR 1020057024851A KR 20057024851 A KR20057024851 A KR 20057024851A KR 100817462 B1 KR100817462 B1 KR 100817462B1
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KR
South Korea
Prior art keywords
formula
compound
deoxy
decarboxylase
gluconate
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Expired - Fee Related
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KR1020057024851A
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English (en)
Korean (ko)
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KR20060091716A (ko
Inventor
필리쁘 마를리에르
폴커 되링
드니 띠보
아네트 크라이메이어
Original Assignee
에볼로직 소시에떼 아노님
마를리에르 테크놀로지스 소시에떼 시빌
로디아 쉬미
필리쁘 마를리에르
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Priority claimed from EP20030013457 external-priority patent/EP1491549A1/en
Application filed by 에볼로직 소시에떼 아노님, 마를리에르 테크놀로지스 소시에떼 시빌, 로디아 쉬미, 필리쁘 마를리에르 filed Critical 에볼로직 소시에떼 아노님
Publication of KR20060091716A publication Critical patent/KR20060091716A/ko
Application granted granted Critical
Publication of KR100817462B1 publication Critical patent/KR100817462B1/ko
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02Acyclic radicals
    • C07H7/027Keto-aldonic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58Aldonic, ketoaldonic or saccharic acids
    • C12P7/602-Ketogulonic acid

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020057024851A 2003-06-24 2004-06-24 2-데하이드로-3-데옥시-d-글루코네이트로부터의2'-데옥시뉴클레오시드 및 2'-데옥시뉴클레오시드전구체들의 제조 Expired - Fee Related KR100817462B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP03013457.1 2003-06-24
EP20030013457 EP1491549A1 (en) 2003-06-24 2003-06-24 Production of 2'-deoxynucleosides and 2'-deoxynucleoside precursors from 2-dehydro-3-deoxy-D-gluconate
EP03027750 2003-12-02
EP03027750.3 2003-12-02

Publications (2)

Publication Number Publication Date
KR20060091716A KR20060091716A (ko) 2006-08-21
KR100817462B1 true KR100817462B1 (ko) 2008-03-31

Family

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KR1020057024851A Expired - Fee Related KR100817462B1 (ko) 2003-06-24 2004-06-24 2-데하이드로-3-데옥시-d-글루코네이트로부터의2'-데옥시뉴클레오시드 및 2'-데옥시뉴클레오시드전구체들의 제조

Country Status (6)

Country Link
US (1) US7858775B2 (enExample)
EP (1) EP1636246B1 (enExample)
JP (2) JP5013865B2 (enExample)
KR (1) KR100817462B1 (enExample)
DK (1) DK1636246T3 (enExample)
WO (1) WO2004113358A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005068642A2 (en) 2003-10-01 2005-07-28 Board Of Trustees Operating Michigan State University Bacterial synthesis of 1,2,4-butanetriol enantiomers
US20090246841A1 (en) * 2008-03-26 2009-10-01 Jamieson Andrew C Methods and compositions for production of acetaldehyde
JP5848028B2 (ja) * 2010-05-21 2016-01-27 三井化学株式会社 2’−デオキシヌクレオシドの製造方法
EP3794116A2 (en) 2018-05-17 2021-03-24 BP Corporation North America Inc. Production of 2-keto-3-deoxy-d-gluconic acid in filamentous fungi
WO2020044379A1 (en) 2018-08-29 2020-03-05 Matis Ohf. Methods for enzymatic processing of polysaccharides from brown algae
EP3963067A1 (en) * 2019-07-11 2022-03-09 BP Corporation North America Inc. Gluconate dehydratase enzymes and recombinant cells

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846794A (en) 1996-05-29 1998-12-08 Roquette Freres Process for the preparation of D-arabitol
US5872247A (en) 1996-06-03 1999-02-16 Fleche; Guy Decarboxylation process for 2-ketoaldonic acids
WO2001014566A2 (en) * 1999-08-20 2001-03-01 Roche Diagnostics Gmbh Enzymatic synthesis of deoxyribonucleosides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3312683A (en) * 1964-06-09 1967-04-04 Hoffmann La Roche Process for producing derivatives of d-glucose
JPH02195870A (ja) * 1989-01-24 1990-08-02 Shinenerugii Sogo Kaihatsu Kiko ザイモモナス・モビリスの新菌株並びにその菌株を使用するレバンの製法
US5759825A (en) * 1991-09-20 1998-06-02 The Scripps Research Institute Method for synthesizing 2-ketoaldonic acids
AU2002353763B2 (en) * 2001-05-04 2007-01-04 University Of Florida Research Foundation, Inc Cloning and sequencing of pyruvate decarboxylase (PDC) genes from bacteria and uses therefor
WO2003070959A2 (en) * 2002-02-22 2003-08-28 Dsm Ip Assets B.V. Process for producing levodione
DK1546596T3 (da) * 2002-07-05 2006-03-20 Technip France Fleksibel rörledning med anti-turbulenskarkasse til transport af hydrocarboner
EP1589021A1 (en) * 2002-12-26 2005-10-26 Mitsui Chemicals, Inc. Process for producing 2-deoxyaldose compound
JP4391328B2 (ja) * 2003-07-10 2009-12-24 三井化学株式会社 新規グルコン酸脱水酵素

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846794A (en) 1996-05-29 1998-12-08 Roquette Freres Process for the preparation of D-arabitol
US5872247A (en) 1996-06-03 1999-02-16 Fleche; Guy Decarboxylation process for 2-ketoaldonic acids
WO2001014566A2 (en) * 1999-08-20 2001-03-01 Roche Diagnostics Gmbh Enzymatic synthesis of deoxyribonucleosides

Also Published As

Publication number Publication date
WO2004113358A1 (en) 2004-12-29
EP1636246A1 (en) 2006-03-22
US7858775B2 (en) 2010-12-28
JP2012082221A (ja) 2012-04-26
KR20060091716A (ko) 2006-08-21
JP5013865B2 (ja) 2012-08-29
JP5766624B2 (ja) 2015-08-19
US20070212759A1 (en) 2007-09-13
DK1636246T3 (en) 2015-11-23
EP1636246B1 (en) 2015-08-19
JP2007527855A (ja) 2007-10-04

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