JP5013865B2 - 2−デヒドロ−3−デオキシ−d−グルコネートからの2’−デオキシヌクレオシド及び2’−デオキシヌクレオシド前駆体の製造 - Google Patents

2−デヒドロ−3−デオキシ−d−グルコネートからの2’−デオキシヌクレオシド及び2’−デオキシヌクレオシド前駆体の製造 Download PDF

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JP5013865B2
JP5013865B2 JP2006516047A JP2006516047A JP5013865B2 JP 5013865 B2 JP5013865 B2 JP 5013865B2 JP 2006516047 A JP2006516047 A JP 2006516047A JP 2006516047 A JP2006516047 A JP 2006516047A JP 5013865 B2 JP5013865 B2 JP 5013865B2
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Prior art keywords
deoxy
gluconate
dehydro
ribose
nucleotide sequence
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Japanese (ja)
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JP2007527855A5 (enExample
JP2007527855A (ja
Inventor
ドーリン ヴォルカー
ティボー ドニ
クライマイヤー アンネット
マルリエル フィリップ
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Rhodia Chimie SAS
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Rhone Poulenc Chimie SA
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Priority claimed from EP20030013457 external-priority patent/EP1491549A1/en
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Publication of JP2007527855A5 publication Critical patent/JP2007527855A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02Acyclic radicals
    • C07H7/027Keto-aldonic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58Aldonic, ketoaldonic or saccharic acids
    • C12P7/602-Ketogulonic acid

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2006516047A 2003-06-24 2004-06-24 2−デヒドロ−3−デオキシ−d−グルコネートからの2’−デオキシヌクレオシド及び2’−デオキシヌクレオシド前駆体の製造 Expired - Fee Related JP5013865B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP03013457.1 2003-06-24
EP20030013457 EP1491549A1 (en) 2003-06-24 2003-06-24 Production of 2'-deoxynucleosides and 2'-deoxynucleoside precursors from 2-dehydro-3-deoxy-D-gluconate
EP03027750 2003-12-02
EP03027750.3 2003-12-02
PCT/EP2004/006848 WO2004113358A1 (en) 2003-06-24 2004-06-24 Production of 2'-deoxynucleosides and 2'-deoxynucleoside precursors from 2-dehydro-3-deoxy-d-gluconate

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012005561A Division JP5766624B2 (ja) 2003-06-24 2012-01-13 2−デヒドロ−3−デオキシ−d−グルコネートからの2’−デオキシヌクレオシド及び2’−デオキシヌクレオシド前駆体の製造

Publications (3)

Publication Number Publication Date
JP2007527855A JP2007527855A (ja) 2007-10-04
JP2007527855A5 JP2007527855A5 (enExample) 2011-08-18
JP5013865B2 true JP5013865B2 (ja) 2012-08-29

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Family Applications (2)

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JP2006516047A Expired - Fee Related JP5013865B2 (ja) 2003-06-24 2004-06-24 2−デヒドロ−3−デオキシ−d−グルコネートからの2’−デオキシヌクレオシド及び2’−デオキシヌクレオシド前駆体の製造
JP2012005561A Expired - Fee Related JP5766624B2 (ja) 2003-06-24 2012-01-13 2−デヒドロ−3−デオキシ−d−グルコネートからの2’−デオキシヌクレオシド及び2’−デオキシヌクレオシド前駆体の製造

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012005561A Expired - Fee Related JP5766624B2 (ja) 2003-06-24 2012-01-13 2−デヒドロ−3−デオキシ−d−グルコネートからの2’−デオキシヌクレオシド及び2’−デオキシヌクレオシド前駆体の製造

Country Status (6)

Country Link
US (1) US7858775B2 (enExample)
EP (1) EP1636246B1 (enExample)
JP (2) JP5013865B2 (enExample)
KR (1) KR100817462B1 (enExample)
DK (1) DK1636246T3 (enExample)
WO (1) WO2004113358A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005068642A2 (en) 2003-10-01 2005-07-28 Board Of Trustees Operating Michigan State University Bacterial synthesis of 1,2,4-butanetriol enantiomers
US20090246841A1 (en) * 2008-03-26 2009-10-01 Jamieson Andrew C Methods and compositions for production of acetaldehyde
JP5848028B2 (ja) * 2010-05-21 2016-01-27 三井化学株式会社 2’−デオキシヌクレオシドの製造方法
EP3794116A2 (en) 2018-05-17 2021-03-24 BP Corporation North America Inc. Production of 2-keto-3-deoxy-d-gluconic acid in filamentous fungi
WO2020044379A1 (en) 2018-08-29 2020-03-05 Matis Ohf. Methods for enzymatic processing of polysaccharides from brown algae
EP3963067A1 (en) * 2019-07-11 2022-03-09 BP Corporation North America Inc. Gluconate dehydratase enzymes and recombinant cells

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3312683A (en) * 1964-06-09 1967-04-04 Hoffmann La Roche Process for producing derivatives of d-glucose
JPH02195870A (ja) * 1989-01-24 1990-08-02 Shinenerugii Sogo Kaihatsu Kiko ザイモモナス・モビリスの新菌株並びにその菌株を使用するレバンの製法
US5759825A (en) * 1991-09-20 1998-06-02 The Scripps Research Institute Method for synthesizing 2-ketoaldonic acids
FR2749307B1 (fr) 1996-05-29 1998-09-04 Roquette Freres Procede de preparation de d-arabitol
FR2749306B1 (fr) * 1996-06-03 1998-08-28 Roquette Freres Procede de decarboxylation des acides 2-cetoaldoniques
DE60042209D1 (de) * 1999-08-20 2009-06-25 Pasteur Institut Enzymatische synthese von deoxyribonucleotiden
AU2002353763B2 (en) * 2001-05-04 2007-01-04 University Of Florida Research Foundation, Inc Cloning and sequencing of pyruvate decarboxylase (PDC) genes from bacteria and uses therefor
WO2003070959A2 (en) * 2002-02-22 2003-08-28 Dsm Ip Assets B.V. Process for producing levodione
DK1546596T3 (da) * 2002-07-05 2006-03-20 Technip France Fleksibel rörledning med anti-turbulenskarkasse til transport af hydrocarboner
EP1589021A1 (en) * 2002-12-26 2005-10-26 Mitsui Chemicals, Inc. Process for producing 2-deoxyaldose compound
JP4391328B2 (ja) * 2003-07-10 2009-12-24 三井化学株式会社 新規グルコン酸脱水酵素

Also Published As

Publication number Publication date
WO2004113358A1 (en) 2004-12-29
EP1636246A1 (en) 2006-03-22
KR100817462B1 (ko) 2008-03-31
US7858775B2 (en) 2010-12-28
JP2012082221A (ja) 2012-04-26
KR20060091716A (ko) 2006-08-21
JP5766624B2 (ja) 2015-08-19
US20070212759A1 (en) 2007-09-13
DK1636246T3 (en) 2015-11-23
EP1636246B1 (en) 2015-08-19
JP2007527855A (ja) 2007-10-04

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