KR100781354B1 - 안구건조증 치료에서 하이드록시에이코사테트라엔산유사체 및 그의 사용 방법 - Google Patents

안구건조증 치료에서 하이드록시에이코사테트라엔산유사체 및 그의 사용 방법 Download PDF

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Publication number
KR100781354B1
KR100781354B1 KR1020027004596A KR20027004596A KR100781354B1 KR 100781354 B1 KR100781354 B1 KR 100781354B1 KR 1020027004596 A KR1020027004596 A KR 1020027004596A KR 20027004596 A KR20027004596 A KR 20027004596A KR 100781354 B1 KR100781354 B1 KR 100781354B1
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South Korea
Prior art keywords
compound
trans
chch
treatment
give
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Expired - Fee Related
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KR1020027004596A
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English (en)
Korean (ko)
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KR20020040849A (ko
Inventor
클림코피터쥐.
헬베르그마크알.
팔크존알.
콘로우레이몬드이.
Original Assignee
알콘, 인코퍼레이티드
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Publication of KR100781354B1 publication Critical patent/KR100781354B1/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020027004596A 1999-11-09 2000-10-23 안구건조증 치료에서 하이드록시에이코사테트라엔산유사체 및 그의 사용 방법 Expired - Fee Related KR100781354B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US16437199P 1999-11-09 1999-11-09
US16438699P 1999-11-09 1999-11-09
US16436999P 1999-11-09 1999-11-09
US60/164,371 1999-11-09
US60/164,369 1999-11-09
US60/164,386 1999-11-09

Publications (2)

Publication Number Publication Date
KR20020040849A KR20020040849A (ko) 2002-05-30
KR100781354B1 true KR100781354B1 (ko) 2007-11-30

Family

ID=27389011

Family Applications (1)

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KR1020027004596A Expired - Fee Related KR100781354B1 (ko) 1999-11-09 2000-10-23 안구건조증 치료에서 하이드록시에이코사테트라엔산유사체 및 그의 사용 방법

Country Status (18)

Country Link
EP (1) EP1228029B1 (https=)
JP (1) JP4663193B2 (https=)
KR (1) KR100781354B1 (https=)
CN (1) CN1390191A (https=)
AR (1) AR029769A1 (https=)
AT (2) ATE271534T1 (https=)
AU (1) AU776254B2 (https=)
BR (1) BR0015424A (https=)
CA (1) CA2386627C (https=)
DE (2) DE60017810T2 (https=)
DK (1) DK1228029T3 (https=)
ES (2) ES2233921T3 (https=)
HK (1) HK1045983B (https=)
MX (1) MXPA02004704A (https=)
PL (1) PL202040B1 (https=)
PT (2) PT1418167E (https=)
TW (1) TWI281395B (https=)
WO (1) WO2001034551A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030109508A1 (en) * 2001-10-11 2003-06-12 Alcon, Inc. Methods for treating dry eye
US8710252B2 (en) * 2006-04-19 2014-04-29 Cecil Pace-Asciak Hepodxilin analog enantiomers

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906467A (en) 1988-03-24 1990-03-06 New York Medical College Novel, long-duration treatment for glaucoma

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696166A (en) * 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906467A (en) 1988-03-24 1990-03-06 New York Medical College Novel, long-duration treatment for glaucoma

Also Published As

Publication number Publication date
DE60017810D1 (de) 2005-03-03
CN1390191A (zh) 2003-01-08
ES2220559T3 (es) 2004-12-16
DE60012358D1 (de) 2004-08-26
PL356105A1 (en) 2004-06-14
BR0015424A (pt) 2002-07-16
PT1418167E (pt) 2005-05-31
AU1226201A (en) 2001-06-06
ATE287866T1 (de) 2005-02-15
ATE271534T1 (de) 2004-08-15
HK1045983A1 (en) 2002-12-20
PT1228029E (pt) 2004-10-29
TWI281395B (en) 2007-05-21
DE60017810T2 (de) 2005-08-25
MXPA02004704A (es) 2004-09-10
ES2233921T3 (es) 2005-06-16
KR20020040849A (ko) 2002-05-30
JP4663193B2 (ja) 2011-03-30
CA2386627A1 (en) 2001-05-17
CA2386627C (en) 2008-12-23
PL202040B1 (pl) 2009-05-29
DE60012358T2 (de) 2005-02-17
AR029769A1 (es) 2003-07-16
DK1228029T3 (da) 2004-10-25
JP2003528042A (ja) 2003-09-24
HK1045983B (en) 2004-12-24
WO2001034551A1 (en) 2001-05-17
HK1063623A1 (en) 2005-01-07
EP1228029B1 (en) 2004-07-21
EP1228029A1 (en) 2002-08-07
AU776254B2 (en) 2004-09-02

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