ATE287866T1 - Hydroxyeicosatetraensäureanaloge und verfahren deren verwendung zur behandlung des trockenen auges - Google Patents

Hydroxyeicosatetraensäureanaloge und verfahren deren verwendung zur behandlung des trockenen auges

Info

Publication number
ATE287866T1
ATE287866T1 AT04003004T AT04003004T ATE287866T1 AT E287866 T1 ATE287866 T1 AT E287866T1 AT 04003004 T AT04003004 T AT 04003004T AT 04003004 T AT04003004 T AT 04003004T AT E287866 T1 ATE287866 T1 AT E287866T1
Authority
AT
Austria
Prior art keywords
hydroxyeicosatetraenacid
analogues
treatment
dry eye
eye
Prior art date
Application number
AT04003004T
Other languages
English (en)
Inventor
John R Falck
Raymond E Conrow
Mark R Hellberg
Peter G Klimko
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Application granted granted Critical
Publication of ATE287866T1 publication Critical patent/ATE287866T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/655Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/46Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT04003004T 1999-11-09 2000-10-23 Hydroxyeicosatetraensäureanaloge und verfahren deren verwendung zur behandlung des trockenen auges ATE287866T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16437199P 1999-11-09 1999-11-09
US16436999P 1999-11-09 1999-11-09
US16438699P 1999-11-09 1999-11-09

Publications (1)

Publication Number Publication Date
ATE287866T1 true ATE287866T1 (de) 2005-02-15

Family

ID=27389011

Family Applications (2)

Application Number Title Priority Date Filing Date
AT04003004T ATE287866T1 (de) 1999-11-09 2000-10-23 Hydroxyeicosatetraensäureanaloge und verfahren deren verwendung zur behandlung des trockenen auges
AT00973791T ATE271534T1 (de) 1999-11-09 2000-10-23 Hydroxyeicosatetraensäureanaloge und verfahren deren verwendung zur behandlung des trockenen auges

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT00973791T ATE271534T1 (de) 1999-11-09 2000-10-23 Hydroxyeicosatetraensäureanaloge und verfahren deren verwendung zur behandlung des trockenen auges

Country Status (18)

Country Link
EP (1) EP1228029B1 (de)
JP (1) JP4663193B2 (de)
KR (1) KR100781354B1 (de)
CN (1) CN1390191A (de)
AR (1) AR029769A1 (de)
AT (2) ATE287866T1 (de)
AU (1) AU776254B2 (de)
BR (1) BR0015424A (de)
CA (1) CA2386627C (de)
DE (2) DE60012358T2 (de)
DK (1) DK1228029T3 (de)
ES (2) ES2220559T3 (de)
HK (2) HK1045983B (de)
MX (1) MXPA02004704A (de)
PL (1) PL202040B1 (de)
PT (2) PT1228029E (de)
TW (1) TWI281395B (de)
WO (1) WO2001034551A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030109508A1 (en) * 2001-10-11 2003-06-12 Alcon, Inc. Methods for treating dry eye
CA2643972C (en) * 2006-04-19 2012-01-03 Peter Demin Hepoxilin analog enantiomers

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906467A (en) 1988-03-24 1990-03-06 New York Medical College Novel, long-duration treatment for glaucoma
US5696166A (en) * 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders

Also Published As

Publication number Publication date
PL356105A1 (en) 2004-06-14
DE60012358D1 (de) 2004-08-26
EP1228029B1 (de) 2004-07-21
TWI281395B (en) 2007-05-21
PT1418167E (pt) 2005-05-31
CN1390191A (zh) 2003-01-08
KR100781354B1 (ko) 2007-11-30
DE60017810D1 (de) 2005-03-03
ES2233921T3 (es) 2005-06-16
EP1228029A1 (de) 2002-08-07
HK1045983B (zh) 2004-12-24
JP2003528042A (ja) 2003-09-24
DE60017810T2 (de) 2005-08-25
HK1045983A1 (en) 2002-12-20
ATE271534T1 (de) 2004-08-15
MXPA02004704A (es) 2004-09-10
WO2001034551A1 (en) 2001-05-17
AR029769A1 (es) 2003-07-16
HK1063623A1 (en) 2005-01-07
PT1228029E (pt) 2004-10-29
DK1228029T3 (da) 2004-10-25
AU776254B2 (en) 2004-09-02
AU1226201A (en) 2001-06-06
PL202040B1 (pl) 2009-05-29
JP4663193B2 (ja) 2011-03-30
CA2386627C (en) 2008-12-23
DE60012358T2 (de) 2005-02-17
BR0015424A (pt) 2002-07-16
KR20020040849A (ko) 2002-05-30
ES2220559T3 (es) 2004-12-16
CA2386627A1 (en) 2001-05-17

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