KR100762156B1 - 핵전사인자 ＮＦ-κＢ의 활성화의 억제제로서의2-히드록시-4-트리플루오로메틸벤조산 유도체의 용도 - Google Patents

핵전사인자 ＮＦ-κＢ의 활성화의 억제제로서의2-히드록시-4-트리플루오로메틸벤조산 유도체의 용도 Download PDF

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KR100762156B1
KR100762156B1 KR1020067026281A KR20067026281A KR100762156B1 KR 100762156 B1 KR100762156 B1 KR 100762156B1 KR 1020067026281 A KR1020067026281 A KR 1020067026281A KR 20067026281 A KR20067026281 A KR 20067026281A KR 100762156 B1 KR100762156 B1 KR 100762156B1
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formula
disease
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acceptable salt
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KR20070006943A (ko
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로까 마뉴엘 멜로스
데 아리바 알베르또 페르난데즈
데 마리아 페르난도 까발깐띠
아꼬스따 아구스띠 미랄레스
끄레스뽀 마리아노 산체즈
라파넬 줄리안 가르시아
달마우 자비에르 포른
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제이. 유라이어크 이 콤파니아 소시에떼아노님
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    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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KR1020067026281A 1998-05-27 1999-05-26 핵전사인자 ＮＦ-κＢ의 활성화의 억제제로서의2-히드록시-4-트리플루오로메틸벤조산 유도체의 용도 Expired - Fee Related KR100762156B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009801154A ES2136581B1 (es) 1998-05-27 1998-05-27 Uso de derivados del acido-2-hidroxi-4-trifluorometilbenzoico para la preparacion de medicamentos utiles para inhibir el factor de transcripcion nuclear nf-kb.
ESP9801154 1998-05-27

Related Parent Applications (1)

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KR1020007013316A Division KR100713601B1 (ko) 1998-05-27 1999-05-26 핵전사인자 ＮＦ-κＢ의 활성화의 억제제로서의2-히드록시-4-트리플루오로메틸벤조산 유도체의 용도

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KR20070006943A KR20070006943A (ko) 2007-01-11
KR100762156B1 true KR100762156B1 (ko) 2007-10-04

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KR1020067026281A Expired - Fee Related KR100762156B1 (ko) 1998-05-27 1999-05-26 핵전사인자 ＮＦ-κＢ의 활성화의 억제제로서의2-히드록시-4-트리플루오로메틸벤조산 유도체의 용도
KR1020007013316A Expired - Fee Related KR100713601B1 (ko) 1998-05-27 1999-05-26 핵전사인자 ＮＦ-κＢ의 활성화의 억제제로서의2-히드록시-4-트리플루오로메틸벤조산 유도체의 용도

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KR1020007013316A Expired - Fee Related KR100713601B1 (ko) 1998-05-27 1999-05-26 핵전사인자 ＮＦ-κＢ의 활성화의 억제제로서의2-히드록시-4-트리플루오로메틸벤조산 유도체의 용도

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US (2) US6414025B1 (https=)
EP (2) EP1082962B1 (https=)
JP (1) JP2002516283A (https=)
KR (2) KR100762156B1 (https=)
AT (1) ATE245987T1 (https=)
AU (1) AU3828699A (https=)
BR (1) BR9911598A (https=)
CA (1) CA2332863A1 (https=)
DE (1) DE69910019T2 (https=)
DK (1) DK1082962T3 (https=)
ES (2) ES2136581B1 (https=)
NO (1) NO20005981L (https=)
PT (1) PT1082962E (https=)
WO (1) WO1999061030A1 (https=)

Families Citing this family (13)

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ES2154242B1 (es) * 1999-09-03 2001-10-16 Uriach & Cia Sa J Nuevos sistemas polimericos biocompatibles portadores de triflusal o htb.
US20040101488A1 (en) * 2000-03-24 2004-05-27 Balaram Ghosh Method for the prevention of septic shock lethality using curcumin
ES2190373B1 (es) * 2001-12-07 2004-10-16 J. URIACH & CIA, S.A. Uso del acido 2-hidroxi- o 2-acetiloxi-4-trifluorometilbenzoico como agente para el tratamiento y prevencion del deterioro cognitivo ligero.
CA2497977A1 (en) 2002-09-20 2004-04-01 Alcon, Inc. Use of cytokine synthesis inhibitors for the treatment of dry eye disorders
JP5780521B2 (ja) 2008-05-28 2015-09-16 リベラジェン・バイオファーマ・インコーポレイテッドＲｅｖｅｒａＧｅｎ ＢｉｏＰｈａｒｍａ，Ｉｎｃ． 疾患を治療するための、ＮＦ−κＢの非ホルモン性ステロイド調節因子
NZ755378A (en) 2009-03-18 2022-07-29 Resverlogix Corp Novel quinazolinones and related compounds for use as anti-inflammatory agents
WO2011127048A2 (en) 2010-04-05 2011-10-13 Validus Biopharma NON-HORMONAL STEROID MODULATORS OF NF-ĸB FOR TREATMENT OF DISEASE
CN103665012B (zh) * 2013-12-06 2016-06-22 辽宁师范大学 新型三氟柳无机药物化合物及合成方法
WO2017004205A1 (en) 2015-06-29 2017-01-05 Reveragen Biopharma, Inc. NON-HORMONAL STEROID MODULATORS OF NF-κB FOR TREATMENT OF DISEASE
US20180016314A1 (en) * 2016-07-12 2018-01-18 Children's Hospital Medical Center Treatment of disease via transcription factor modulation
JP6923659B2 (ja) * 2016-10-14 2021-08-25 アンスティテュ パスツール デ モンテビデオＩｎｓｔｉｔｕｔ Ｐａｓｔｅｕｒ Ｄｅ Ｍｏｎｔｅｖｉｄｅｏ 多能性抗炎症及び代謝調節剤を用いた炎症関連症状の治療方法
KR101975603B1 (ko) 2018-09-14 2019-08-28 이영문 조력 발전장치
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4096252A (en) * 1976-06-10 1978-06-20 J. Uriach & Cia S.A. 4-Trifluoromethylbenzoic acid derivatives as thromboembolic agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1276071B1 (it) * 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4096252A (en) * 1976-06-10 1978-06-20 J. Uriach & Cia S.A. 4-Trifluoromethylbenzoic acid derivatives as thromboembolic agents

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DE69910019D1 (de) 2003-09-04
NO20005981D0 (no) 2000-11-27
JP2002516283A (ja) 2002-06-04
EP1362592A1 (en) 2003-11-19
ATE245987T1 (de) 2003-08-15
CA2332863A1 (en) 1999-12-02
WO1999061030A1 (es) 1999-12-02
EP1082962B1 (en) 2003-07-30
US20030032630A1 (en) 2003-02-13
US6610745B2 (en) 2003-08-26
DK1082962T3 (da) 2003-11-24
NO20005981L (no) 2000-12-12
PT1082962E (pt) 2003-11-28
KR20010052404A (ko) 2001-06-25
ES2204129T3 (es) 2004-04-16
BR9911598A (pt) 2001-02-13
KR20070006943A (ko) 2007-01-11
EP1082962A1 (en) 2001-03-14
ES2136581A1 (es) 1999-11-16
DE69910019T2 (de) 2004-05-06
ES2136581B1 (es) 2000-09-16
AU3828699A (en) 1999-12-13
KR100713601B1 (ko) 2007-05-02
US6414025B1 (en) 2002-07-02

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