KR100731263B1 - 필름층 내에 존재하는 활성 성분을 물 또는 수성 시스템으로 방출하기 위한 필름 형태의 적층 제제의 제조 방법 - Google Patents
필름층 내에 존재하는 활성 성분을 물 또는 수성 시스템으로 방출하기 위한 필름 형태의 적층 제제의 제조 방법 Download PDFInfo
- Publication number
- KR100731263B1 KR100731263B1 KR1020027006077A KR20027006077A KR100731263B1 KR 100731263 B1 KR100731263 B1 KR 100731263B1 KR 1020027006077 A KR1020027006077 A KR 1020027006077A KR 20027006077 A KR20027006077 A KR 20027006077A KR 100731263 B1 KR100731263 B1 KR 100731263B1
- Authority
- KR
- South Korea
- Prior art keywords
- film
- delete delete
- polymer solution
- solvent
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31855—Of addition polymer from unsaturated monomers
- Y10T428/31909—Next to second addition polymer from unsaturated monomers
- Y10T428/31913—Monoolefin polymer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31855—Of addition polymer from unsaturated monomers
- Y10T428/31909—Next to second addition polymer from unsaturated monomers
- Y10T428/31928—Ester, halide or nitrile of addition polymer
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Laminated Bodies (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19954245A DE19954245A1 (de) | 1999-11-11 | 1999-11-11 | Mehrschichtige filmförmige Zubereitung aus hydrophilen Polymeren zur schnellen Freisetzung von Wirkstoffen |
| DE19954245.7 | 1999-11-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20020058006A KR20020058006A (ko) | 2002-07-12 |
| KR100731263B1 true KR100731263B1 (ko) | 2007-06-21 |
Family
ID=7928670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020027006077A Expired - Fee Related KR100731263B1 (ko) | 1999-11-11 | 2000-11-03 | 필름층 내에 존재하는 활성 성분을 물 또는 수성 시스템으로 방출하기 위한 필름 형태의 적층 제제의 제조 방법 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7332230B1 (https=) |
| EP (1) | EP1227801B1 (https=) |
| JP (1) | JP4213383B2 (https=) |
| KR (1) | KR100731263B1 (https=) |
| CN (1) | CN1407886A (https=) |
| AR (1) | AR026427A1 (https=) |
| AT (1) | ATE339193T1 (https=) |
| AU (1) | AU778619B2 (https=) |
| CA (1) | CA2391406C (https=) |
| DE (2) | DE19954245A1 (https=) |
| ES (1) | ES2272344T3 (https=) |
| IL (2) | IL149573A0 (https=) |
| WO (1) | WO2001034121A2 (https=) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10107659B4 (de) | 2001-02-19 | 2008-03-13 | Lts Lohmann Therapie-Systeme Ag | Mucoadhäsive zerfallsfähige Arzneizubereitung zur Wirkstoffverabreichung in der Veterinär- und Humanmedizin |
| JP5089840B2 (ja) * | 2001-09-25 | 2012-12-05 | 救急薬品工業株式会社 | ニコチン含有フィルム製剤 |
| US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
| US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
| US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
| US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
| US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
| KR20110004921A (ko) * | 2002-05-16 | 2011-01-14 | 규큐 야쿠힝 고교 가부시키가이샤 | 속용성 필름형상 제제 |
| US20040202698A1 (en) * | 2003-04-02 | 2004-10-14 | The Procter & Gamble Company | Drug delivery systems comprising an encapsulated active ingredient |
| DE20307771U1 (de) * | 2003-05-19 | 2004-09-23 | Cofresco Frischhalteprodukte Gmbh & Co. Kg | Beschichtung und Beutel |
| MXPA06001776A (es) * | 2003-08-15 | 2007-09-07 | Qlt Usa Inc | Sistema de suministro de farmaco transmucosal biocorrosivo, adhesivo. |
| US20050079253A1 (en) * | 2003-10-10 | 2005-04-14 | Hiroshi Nakamura | Bilayer edible sheet |
| CN104397869B (zh) | 2003-11-07 | 2016-06-08 | 美国无烟烟草有限责任公司 | 烟草组合物 |
| US8627828B2 (en) | 2003-11-07 | 2014-01-14 | U.S. Smokeless Tobacco Company Llc | Tobacco compositions |
| US7727576B2 (en) | 2004-04-16 | 2010-06-01 | Hewlett-Packard Development Company, L.P. | System and a method for producing layered oral dosage forms |
| EP1748762B1 (de) | 2004-05-28 | 2013-12-18 | AbbVie Deutschland GmbH & Co KG | Dosierungsform, erhältlich aus einer ein anorganisches pigment umfassenden pulvermischung |
| US20050281757A1 (en) * | 2004-06-17 | 2005-12-22 | Sayed Ibrahim | Oral care film |
| JP5215175B2 (ja) * | 2005-05-25 | 2013-06-19 | ユーエス スモークレス タバコ カンパニー リミテッド ライアビリティ カンパニー | タバコ組成物 |
| FR2912915B1 (fr) * | 2007-02-28 | 2012-11-16 | Pf Medicament | Film a desintegration rapide pour l'administration buccale de substances actives. |
| US20080260836A1 (en) * | 2007-04-18 | 2008-10-23 | Thomas James Boyd | Films Comprising a Plurality of Polymers |
| ES2699077T3 (es) | 2009-06-12 | 2019-02-07 | Sunovion Pharmaceuticals Inc | Apomorfina sublingual |
| US9549842B2 (en) | 2011-02-04 | 2017-01-24 | Joseph E. Kovarik | Buccal bioadhesive strip and method of treating snoring and sleep apnea |
| US8701671B2 (en) | 2011-02-04 | 2014-04-22 | Joseph E. Kovarik | Non-surgical method and system for reducing snoring |
| PL2415382T3 (pl) | 2010-08-06 | 2013-02-28 | Electrolux Home Products Corp Nv | Zmywarka nablatowa |
| EP2415383B1 (en) | 2010-08-06 | 2013-06-05 | Electrolux Home Products Corporation N.V. | Table top dishwasher |
| US9149959B2 (en) | 2010-10-22 | 2015-10-06 | Monosol Rx, Llc | Manufacturing of small film strips |
| PT2651357T (pt) | 2010-12-16 | 2020-06-17 | Sunovion Pharmaceuticals Inc | Películas sublinguais |
| US11844720B2 (en) | 2011-02-04 | 2023-12-19 | Seed Health, Inc. | Method and system to reduce the likelihood of dental caries and halitosis |
| US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
| US12279989B2 (en) | 2011-02-04 | 2025-04-22 | Seed Health, Inc. | Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity |
| US11951140B2 (en) | 2011-02-04 | 2024-04-09 | Seed Health, Inc. | Modulation of an individual's gut microbiome to address osteoporosis and bone disease |
| US12257272B2 (en) | 2015-12-24 | 2025-03-25 | Seed Health, Inc. | Method and system for reducing the likelihood of developing depression in an individual |
| US11951139B2 (en) | 2015-11-30 | 2024-04-09 | Seed Health, Inc. | Method and system for reducing the likelihood of osteoporosis |
| US12533312B2 (en) | 2011-02-04 | 2026-01-27 | Seed Health, Inc. | Method and system for preventing sore throat in humans |
| US20140271783A1 (en) * | 2011-10-14 | 2014-09-18 | Purdue Research Foundation | Prefabricated pharmaceutical dosage forms from functional polymer films |
| WO2014018075A1 (en) | 2012-07-23 | 2014-01-30 | Crayola, Llc | Dissolvable films and methods of using the same |
| US12005085B2 (en) | 2013-12-20 | 2024-06-11 | Seed Health, Inc. | Probiotic method and composition for maintaining a healthy vaginal microbiome |
| US11969445B2 (en) | 2013-12-20 | 2024-04-30 | Seed Health, Inc. | Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH |
| US12246043B2 (en) | 2013-12-20 | 2025-03-11 | Seed Health, Inc. | Topical application to treat acne vulgaris |
| US11998574B2 (en) | 2013-12-20 | 2024-06-04 | Seed Health, Inc. | Method and system for modulating an individual's skin microbiome |
| US11839632B2 (en) | 2013-12-20 | 2023-12-12 | Seed Health, Inc. | Topical application of CRISPR-modified bacteria to treat acne vulgaris |
| US11833177B2 (en) | 2013-12-20 | 2023-12-05 | Seed Health, Inc. | Probiotic to enhance an individual's skin microbiome |
| US12329783B2 (en) | 2013-12-20 | 2025-06-17 | Seed Health, Inc. | Method and system to improve the health of a person's skin microbiome |
| US11980643B2 (en) | 2013-12-20 | 2024-05-14 | Seed Health, Inc. | Method and system to modify an individual's gut-brain axis to provide neurocognitive protection |
| US11826388B2 (en) | 2013-12-20 | 2023-11-28 | Seed Health, Inc. | Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation |
| ES2909467T3 (es) | 2013-12-31 | 2022-05-06 | Johnson & Johnson Consumer Inc | Proceso para formar un producto de película con forma |
| MX374704B (es) | 2013-12-31 | 2025-03-06 | Johnson & Johnson Consumer Inc | Proceso de una sola pasada para formar un producto de película conformada en capas múltiples |
| EP3091968B1 (en) | 2013-12-31 | 2025-10-29 | Kenvue Brands LLC | Process for forming a multilayered shaped film |
| US20170360942A1 (en) * | 2014-12-09 | 2017-12-21 | Monosol Rx, Llc | Linear polysaccharide based film products |
| EP4578461A3 (en) | 2015-04-21 | 2025-09-03 | Sumitomo Pharma America, Inc. | Methods of treating parkinsons disease by administration of apomorphine to an oral mucosa |
| WO2017192921A1 (en) | 2016-05-05 | 2017-11-09 | Monosol Rx, Llc | Enhanced delivery epinephrine compositions |
| US12427121B2 (en) | 2016-05-05 | 2025-09-30 | Aquestive Therapeutics, Inc. | Enhanced delivery epinephrine compositions |
| US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
| US12433850B2 (en) | 2016-05-05 | 2025-10-07 | Aquestive Therapeutics, Inc. | Enhanced delivery epinephrine and prodrug compositions |
| CN106237338A (zh) * | 2016-09-05 | 2016-12-21 | 四川大学 | 一种制备层状生物降解高分子药物控释材料的方法 |
| EP3691610A1 (en) | 2017-10-07 | 2020-08-12 | Zim Laboratories Limited | Process for the preparation of bi/multi-layer film, multi-layered film produced thereof and apparatus for producing such multi-layer films |
| DE102017127452A1 (de) * | 2017-11-21 | 2019-05-23 | Lts Lohmann Therapie-Systeme Ag | Wasserlösliche Polymerklebschichten |
| DE102018101778A1 (de) * | 2018-01-26 | 2019-08-01 | Lts Lohmann Therapie-Systeme Ag | Mehrschichtiger Oraler Dünnfilm |
| DE102021100783A1 (de) | 2021-01-15 | 2022-07-21 | Lts Lohmann Therapie-Systeme Ag. | Mehrschichtiger oraler dünnfilm |
| US12465564B2 (en) | 2021-10-25 | 2025-11-11 | Aquestive Therapeutics, Inc. | Oral and nasal compositions and methods of treatment |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998017251A1 (en) * | 1996-10-18 | 1998-04-30 | Virotex Corporation | Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2700035A (en) * | 1950-08-26 | 1955-01-18 | Du Pont | Production of polyvinyl alcohol |
| US3511728A (en) * | 1964-03-16 | 1970-05-12 | Westinghouse Electric Corp | Methods for making flat electrical cables |
| JPS5770816A (en) * | 1980-10-17 | 1982-05-01 | Ono Pharmaceut Co Ltd | Multilayered film preparation of prostagladin of prolonged action |
| US4439581A (en) * | 1981-09-03 | 1984-03-27 | Kanzaki Paper Manufacturing Co., Ltd. | Method for the production of microcapsules |
| JPS58134019A (ja) * | 1982-02-05 | 1983-08-10 | Ono Pharmaceut Co Ltd | プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法 |
| JPS61280423A (ja) * | 1985-06-05 | 1986-12-11 | Kiyuukiyuu Yakuhin Kogyo Kk | 口腔内粘膜貼付剤 |
| JPS63171565A (ja) * | 1987-01-07 | 1988-07-15 | 積水化学工業株式会社 | 口腔粘膜貼付用構成体およびその製造方法 |
| WO1995005416A2 (en) * | 1993-08-19 | 1995-02-23 | Cygnus Therapeutic Systems | Water-soluble pressure-sensitive mucoadhesive and devices provided therewith for emplacement in a mucosa-lined body cavity |
| JPH07196992A (ja) * | 1993-12-28 | 1995-08-01 | Nippon Autom Kk | 制振シート |
| JP2791317B2 (ja) * | 1995-12-26 | 1998-08-27 | 株式会社三和化学研究所 | 多層フィルム製剤 |
| US5760484A (en) * | 1997-02-11 | 1998-06-02 | Mosel Vitelic Inc. | Alignment mark pattern for semiconductor process |
-
1999
- 1999-11-11 DE DE19954245A patent/DE19954245A1/de not_active Withdrawn
-
2000
- 2000-11-03 AU AU19981/01A patent/AU778619B2/en not_active Expired
- 2000-11-03 EP EP00983105A patent/EP1227801B1/de not_active Expired - Lifetime
- 2000-11-03 ES ES00983105T patent/ES2272344T3/es not_active Expired - Lifetime
- 2000-11-03 KR KR1020027006077A patent/KR100731263B1/ko not_active Expired - Fee Related
- 2000-11-03 DE DE50013472T patent/DE50013472D1/de not_active Expired - Lifetime
- 2000-11-03 US US10/129,835 patent/US7332230B1/en not_active Expired - Lifetime
- 2000-11-03 JP JP2001536121A patent/JP4213383B2/ja not_active Expired - Lifetime
- 2000-11-03 CA CA002391406A patent/CA2391406C/en not_active Expired - Lifetime
- 2000-11-03 IL IL14957300A patent/IL149573A0/xx active IP Right Grant
- 2000-11-03 WO PCT/EP2000/010856 patent/WO2001034121A2/de not_active Ceased
- 2000-11-03 AT AT00983105T patent/ATE339193T1/de not_active IP Right Cessation
- 2000-11-03 CN CN00816734A patent/CN1407886A/zh active Pending
- 2000-11-10 AR ARP000105935A patent/AR026427A1/es unknown
-
2002
- 2002-05-09 IL IL149573A patent/IL149573A/en unknown
-
2007
- 2007-10-31 US US11/932,345 patent/US7803430B2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998017251A1 (en) * | 1996-10-18 | 1998-04-30 | Virotex Corporation | Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE339193T1 (de) | 2006-10-15 |
| EP1227801A2 (de) | 2002-08-07 |
| ES2272344T3 (es) | 2007-05-01 |
| AU1998101A (en) | 2001-06-06 |
| JP2003513906A (ja) | 2003-04-15 |
| US20080057087A1 (en) | 2008-03-06 |
| DE50013472D1 (de) | 2006-10-26 |
| CN1407886A (zh) | 2003-04-02 |
| US7332230B1 (en) | 2008-02-19 |
| IL149573A (en) | 2007-09-20 |
| US7803430B2 (en) | 2010-09-28 |
| AR026427A1 (es) | 2003-02-12 |
| IL149573A0 (en) | 2002-11-10 |
| CA2391406A1 (en) | 2001-05-17 |
| WO2001034121A3 (de) | 2002-04-11 |
| KR20020058006A (ko) | 2002-07-12 |
| JP4213383B2 (ja) | 2009-01-21 |
| EP1227801B1 (de) | 2006-09-13 |
| AU778619B2 (en) | 2004-12-16 |
| WO2001034121A2 (de) | 2001-05-17 |
| DE19954245A1 (de) | 2001-07-19 |
| CA2391406C (en) | 2008-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
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