KR100698849B1 - Cosmetic composition with the effect of protecting skins by ultraviolet rays - Google Patents

Abstract

A cosmetic composition comprising an oriental tea extract is provided to be able to protect skin from various stresses by containing a mixture of oriental tea extract, thereby taking care of the skin to be soft and gloss. The cosmetic composition having skin protection effect against UV contains an oriental tea extract obtained by extracting a mixture tea consisting of arrowroot tea, mulberry fruit tea, persimmon leaf tea, cinnamon tea, mugwort tea, chrysanthemum tea, and green tea through low temperature ultrasonication extraction method. The mixture tea contains 10-20 wt.% of the arrowroot tea, 10-20 wt.% of the mulberry fruit tea, 10-20 wt.% of the persimmon leaf tea, 10-20 wt.% of the cinnamon tea, 10-30 wt.% of the mugwort tea, chrysanthemum tea, and 10-30 wt.% of the green tea based on each of the dried weight. The cosmetic composition further comprises a medium wavelength UV absorbent.

Description

Cosmetic composition with the effect of protecting skins by ultraviolet rays

1 is a graph showing the sunscreen effect according to the concentration of the herbal tea extract of the present invention,

2 is a graph showing the antioxidant effect of DPPH scavenging ability of the herbal tea extract of the present invention,

Figure 3 is a graph showing the scavenging activity of the hydroxy radicals (hydroxy radical) of the herbal tea extract of the present invention,

Figure 4 is a graph showing the scavenging activity of the superoxide anion (superoxide anion) of the herbal tea extract of the present invention,

5 is a graph showing the inhibitory ability of collagenase (collagenase) of the herbal tea extract of the present invention,

6 is a graph showing the inhibitory ability of lipoxygenase of the herbal tea extract of the present invention,

The present invention relates to a cosmetic composition having a skin protection effect against ultraviolet rays, and more particularly to ultraviolet rays by containing extracts of the main herbal tea components consisting of brown root tea, mulberry tea, persimmon leaf tea, cinnamon tea, mugwort tea, chrysanthemum tea, green tea It relates to a cosmetic composition that provides a skin protective effect for.

Generally, ultraviolet rays included in the sun's rays are divided into long, medium, and short wavelengths according to their wavelength ranges. These ultraviolet rays are known to cause various side effects on the skin.

Short wavelength ultraviolet rays in ultraviolet light are very harmful to the human body, but until now they are absorbed by the ozone layer in the atmosphere and hardly reach the earth's surface. Medium-wavelength ultraviolet rays, which cause photoallergy and more energy, cause erythema, blistering, burns, skin cancer, pigmentation, and degeneration of skin proteins. Importantly, various sunscreens have been developed to block ultraviolet rays.

Conventional ultraviolet absorbers include compounds such as benzophenone derivatives, paraamino derivatives, cinnamic acid derivatives and triazine derivatives, and inorganic pigments such as titanium dioxide and zinc oxide have been used as ultraviolet scatterers. It absorbs only the ultraviolet rays of the intestinal ultraviolet region and is a chemical synthetic substance, which is likely to cause other side effects on the skin, such as irritation and allergy. In addition, UV scattering agent is opaque when used as a cosmetic in addition to ultraviolet light as well as visible light has been pointed out that the feeling is poor when applied to the skin.

On the other hand, a substance having an ultraviolet absorbing action extracted from a natural product generally has a low irritation, and has other pharmacological actions such as anti-inflammatory, astringent, and antimicrobial effects, and thus has been promising as a ultraviolet absorber conventionally incorporated into cosmetics. Efforts have been made to search for and isolate ultraviolet absorbers contained in natural products.

The present invention is to solve the above problems, as a part of the research to overcome the disadvantages of the known sunscreen and to develop a better sunscreen considering the characteristics of the herbal extract extracted with water or organic solvent from various natural products As a result, while researching to develop a cosmetic composition having a skin protection effect, it contains extracts of the major herbal tea components consisting of brown root tea, odyssey tea, persimmon leaf tea, cinnamon tea, mugwort tea, chrysanthemum tea, and green tea, which protects the skin against UV rays. It is to provide an excellent cosmetic composition.

Hereinafter, the present invention will be described in more detail.

The present invention relates to a cosmetic composition having a skin protection effect against ultraviolet rays, and more specifically, to absorb ultraviolet rays by containing extracts of the main herbal tea components consisting of brown root tea, mulberry tea, persimmon leaf tea, cinnamon tea, mugwort tea, chrysanthemum tea, green tea It has an effect, has a high non-absorption property, and has good solubility, affinity, and stability for various bases, additives, and organic solvents for cosmetics, and provides a synergistic effect of remarkably increasing the UV protection index, especially when used in combination with a conventional sunscreen agent. It is.

Cosmetic composition according to the present invention is a cosmetic composition containing a herbal tea extract having a skin protection effect against ultraviolet rays, consisting of brown root tea, mulberry tea, persimmon leaf tea, cinnamon tea, mugwort tea, chrysanthemum tea, green tea based on 100% by weight of the cleaning composition It relates to a cosmetic composition having a skin protection effect against ultraviolet light, characterized in that it contains herbal tea extract extracted by a low temperature ultrasonic extraction method.

In the herbal tea composition according to the present invention, the composition of the main herbal tea raw materials consisting of brown root tea, mulberry tea, persimmon leaf tea, cinnamon tea, mugwort tea, chrysanthemum tea, and green tea is based on the respective dry weights of brown root tea 10-20% by weight, mulberry tea 10 to 20% by weight, persimmon leaf tea 10 to 20% by weight, cinnamon tea 10 to 20% by weight, mugwort tea 10 to 20% by weight, chrysanthemum tea 10 to 30% by weight, green tea 10 to 30% by weight is used in combination.

At this time, brown tea, mulberry tea, persimmon leaf tea, cinnamon tea, mugwort tea, chrysanthemum tea, green tea as a raw material of the herbal tea extract of the present invention uses a low-temperature ultrasonic extraction method to improve the extraction efficiency.

The low temperature here means less than 60 degrees Celsius.

At this time, as the herbal tea is generally concerned, each raw material is composed of the proper amount blending ratio as described above to avoid the extraction temperature at the high temperature or cryogenic level, and the purpose of the selective removal of unnecessary components and selective reinforcement of active ingredients, The disadvantages of inadequate selectivity were overcome by ultrasonic extraction.

In other words, efforts have been made to minimize the effects of changes in the composition of plant extracts that may occur during extraction. The ultrasonic extraction method stabilizes the unstable structure of various useful components and has an advantage of effectively extracting the active ingredient of natural products by penetrating deeply into plant raw materials by various ranges of ultrasonic waves.

In the ultrasonic extraction method, the ultrasonic wave refers to a sound of high frequency that cannot be heard by the human ear.

The ultrasonic extraction method used in the preparation of the herbal tea extract of the present invention has the advantage that the intensity of the ultrasonic energy change can be adjusted according to the raw material to be extracted. Therefore, the extraction efficiency is very high depending on the raw materials, and the possibility of denaturation and destruction of the active ingredient exhibiting pharmacological activity is minimized, and the production speed is faster than that of the conventional hydrothermal extraction method, which shortens the extraction time and thus has the characteristics of low cost and low energy use. It was confirmed.

Extraction method of brown root tea, mulberry tea, persimmon leaf tea, cinnamon tea, mugwort tea, chrysanthemum tea, green tea used in the preparation of the herbal tea extract of the present invention, after washing the raw material with water first, finely pulverized and ground 1 to 10% by weight Natural herbal tea extract by dividing into methanol, ethanol, or 1 to 50% of their mixed solvent for 1 to 5 days, preferably 3 days, and using a low temperature ultrasonic extraction method for 1 to 5 hours. Maximize the extraction of active ingredients. In this case, each of methanol, ethanol, or one of their mixed solvents may be selected to mix 10 to 70% by weight, and 10 to 40% by weight of water to be mixed solvents, which may be classified according to the properties of the raw material, and extracted by an ultrasonic method.

To the herbal tea mixtures mixed in the above blending ratio, an organic solvent or purified water containing 1 to 5 times ethanol or butylene glycol is added and added during cosmetic preparation.

When the herbal tea extract according to the present invention is used in a cosmetic composition, the herbal tea extract prepared above is characterized in that it contains 0.1 to 5% by weight, preferably 2% by weight.

At this time, when the addition of 0.1% by weight or less, the effect of protecting the skin against ultraviolet rays of the present invention is insufficient, and when it is used at 5% by weight or more, the unique odors and colors according to the intrinsic flavor of the final product are strong, which makes it difficult to apply the final product. This was limited to 5% by weight, more preferably 2% by weight.

Cosmetic compositions having a soothing effect on the ultraviolet light according to the present invention may have a conventional formulation, for example, formulated in softening longevity, astringent longevity, nourishing longevity, nutrition cream, body lotion, body oil, body essence, etc. Can be. The composition of each of these formulations may contain a variety of bases and additives necessary for the formulation of the formulation and are suitable, and the types and amounts of these components can be readily selected by those skilled in the art. Below, the typical skin and lotion composition of the cosmetic composition which has a skin protection effect to an ultraviolet-ray is demonstrated to an example.

In addition, the cosmetic composition having a skin protection effect against ultraviolet rays according to the present invention may be used according to a conventional method of use, and the number of times of use may vary depending on the user's skin condition or taste.

Hereinafter, the cosmetic composition having the skin protection effect against ultraviolet rays of the present invention will be described in more detail with reference to the present invention, but the present invention is not limited to these examples.

Example 1 Preparation of Herbal Tea Extract (Oriental Tea Newplex-Cosmecca)

Herbal tea extract was used as a dried herbal tea raw material dried state.

Extraction method of brown root tea, mulberry tea, persimmon leaf tea, cinnamon tea, mugwort tea, chrysanthemum tea, green tea used in the preparation of the herbal tea extract of the present invention, after washing the raw material with water first, finely pulverized and ground 1 to 10% by weight To maximize the extraction of the natural herbal tea extract by dividing into three stages of immersion in ethanol and using a low-temperature ultrasonic extraction method for 3 hours. At this time, the raw material may be extracted by a low temperature ultrasonic extraction method by mixing 70: 30% by weight of ethanol and water as a mixed solvent.

As shown in Table 1, the mixed herbal tea raw materials were extracted by low temperature ultrasonic extraction, filtered, and concentrated under reduced pressure to obtain 2 g of herbal tea extracts.

turn Kinds Weight before extraction (g) Weight after extraction (g) One Brown car 1.0 2 Audi 1.0 3 Persimmon Leaf Tea 1.0 4 Cinnamon Tea 1.0 5 Mugwort tea 1.0 6 Chrysanthemum tea 2.0 7 green tea 2.5 Sum 10.0 0.2

 Example 2 Preparation of Skin Lotion with Skin Protection Effect According to the Present Invention

A skin lotion was prepared at the composition ratio as shown in Table 2 below. The alcohol part was prepared by dissolving in the order of MP, tween 20, NP-12 in alcohol which was produced in a grain and distilled at 78 ° C. The purified water part was glycerin, 1,3-BG, DC-193, hyaluronic acid in sterilized purified water. Prepared by dissolving in the order of, allantoin, citric acid, citric acid, and then mixed with the herbal tea extract prepared in Example 1 to prepare a skin lotion.

Classification Raw material name Weight (% by weight) Alcohol part ethanol 7 Methylparahydroxybenzoic acid 0.1 tween-20 0.2 Nonylphenylether-12 0.2 Purified water Purified water 89.01 glycerin 0.1 1,3-butylene glycol 0.2 Alanine 193 0.1 Hyaluronic acid 0.5 Allantoin 0.05 Citric acid 0.01 Citric acid 0.03 Herbal tea parts Herbal Tea Addition 2.5 Sum 100

Example 3 Preparation of Milk Lotion with Skin Protection Effect According to the Present Invention

Milk lotion was prepared in the same manner as in Example 2.

Classification Raw material name Weight (% by weight) Alcohol part Stearic acid 2.1 Cetanol 1.3 Liquid paraffin 7.0 Squalene 0.5 Isopropyl myristate 1.0 Glyceryl Monostearate 0.5 Arasel-60 0.85 tween-20 0.1 Isostearyl-isostearate 0.5 Propylparaben 0.1 Alanine 200F / 100CS 0.1 Purified water Purified water 69.65 Triethanolamine 0.7 Propylene glycol 7.0 glycerin 3.0 Methylparahydroxybenzoic acid 0.1 Herbal tea Herbal Tea Extract 5.5 Sum 100

Experimental Example 1 Check the skin irritation and protective effect of the skin lotion according to the present invention

Apply the skin lotion prepared in Example 2 (10 m / 5 cm ² ) to the forearm of 30 healthy males and females (15 males and 15 females) and shield the rest with aluminum foil for 30 minutes. Subsequently, a long wavelength ultraviolet ray was irradiated at a dose of 10.2 J / cm ² using an ultraviolet irradiator, and skin conditions (erythema, edema, papules, etc.) were observed 24 hours later. As a result, skin side effects such as erythema do not occur on the skin, and thus the skin lotion has no phototoxicity and has a skin protection effect.

Experimental Example 2: Confirmation of skin irritation and protective effect of milk lotion according to the present invention

Apply the milk lotion prepared in Example 3 (10m / 5cm ² ) to the forearm of 30 healthy males and females (15 males, 15 females) and shield the rest with aluminum foil for 30 minutes. Subsequently, a long wavelength ultraviolet ray was irradiated at a dose of 10.2 J / cm ² using an ultraviolet irradiator, and skin conditions (erythema, edema, papules, etc.) were observed 24 hours later. As a result, the side effects such as erythema do not occur on the skin, and thus the milk lotion has no phototoxicity and has a skin protection effect.

Experimental Example 3: Skin stability confirmation test of skin lotion and milk lotion according to the present invention

The skin patch and milk lotion prepared in Examples 2 and 3 were subjected to a human patch test on the forearm of 30 healthy adult men and women (15 males and 15 females). Wipe the forearm of the subject well with 70% ethanol, and then place a pin chamber containing 20 μl of the skin lotion and milk lotion prepared in Examples 2 and 3 on a conventional cosmetic base using adhesive tape for 24 hours. Closed attachment. After 24 hours, the adhesive tape and the pin chamber were removed, and the sample remaining on the skin with a gauze was lightly removed, and then the skin condition was observed, and again after 24 hours. Experimental results As shown in Table 4, in the human patch test to confirm the skin irritation of the skin lotion and milk lotion according to the present invention did not show a positive response was confirmed that there is no irritation to the human skin.

sample After 24 hours (n = 30) After 48 hours (n = 30) Remarks Skin lotion 0/30 0/30 Number of reaction quantums / total number of targets Milk lotion 0/30 0/30

Experimental Example 4: UV blocking effect according to the concentration of the herbal tea extract of the present invention

As a control, 1, 3-butylene glycol 40% and Phenonip 0.2% using the herbal tea extract of the present invention according to the concentration according to the concentration of ultraviolet light according to the ultraviolet ray blocking effect as shown in Figure 1 Absorption capacity was observed in the concentration-dependent form of the herbal tea extract was confirmed that the sunscreen effect by Oriental Tea Newplex-Cosmecca.

Experimental Example 5 Antioxidant Effect by DPPH Scavenging Activity

Skin aging processes with free radicals include lipid peroxidation, DNA oxidation, melanogenesis, cleavage of connective tissue and abnormal crosslinks. Most of these reactions are radical reactions that involve an automatic oxidation process. Antioxidants are responsible for blocking the automatic oxidation in vivo. The greater the reducing power as an electron-giving ability, the stronger the antioxidant. A reagent that measures the reducing power of antioxidants is 1,1-diphenyl-2 picrylhydrazyl radical (DPPH). DPPH exists as a radical of a stabilized structure of the nitrogen center in the compound. Maximum absorption at 517 nm is shown and when reduced, absorption is lost at 517 nm. The magnitude of the reducing power of the herbal tea extract of the present invention is expressed by the radical scavenging activity (SCcavenging activity, SC50) and SC50 represents the concentration required to reduce the concentration of DPPH by 50%. The herbal tea extract of the present invention is shown in Figure 2 the results shown by measuring the SC50 by concentration. According to the concentration of the herbal tea extract seen in Figure 2 it was confirmed that there is an antioxidant effect according to the DPPH scavenging ability.

Experimental Example 6: Determination of the scavenging activity of the hydroxyl radical

Hydroxyl radicals are the most powerful free radicals that damage cells and are known to be active oxygen species, which are the main sources of peroxidation of lipids in the skin membranes and in particular in DNA and connective tissue matrix damage. In particular, photosensitization reactions that begin with ultraviolet absorption produce superoxides and hydrogen peroxide and they participate in the production of more dangerous hydroxyl radicals in vivo. That is, superoxides can reduce iron ions and copper ions, and reduced iron and copper reduce hydrogen peroxide, resulting in hydroxyl radicals.

Herbal tea extract of the present invention is shown in Figure 3 by measuring the ability to eliminate the hydroxyl radicals produced by the Fenton reaction in vitro. That is, as shown in Figure 3, the herbal tea extract shows the scavenging of the hydroxyl radical according to the concentration, the hydroxyl radical scavenging activity (SC 50) was excellent and showed 5.2µl / ml.

Experimental Example 7: Determination of superoxide anion scavenging activity

Superoxide anion among the active oxygen is produced by the photosensitization reaction that begins with ultraviolet absorption, and is converted to hydrogen peroxide by the SOD (Superoxide dismutase) enzyme present in the living body. Superoxides and hydrogen peroxides are less reactive and therefore rarely directly involved in tissue cell damage, but participate in the production of more dangerous hydroxy radicals. That is, the superoxide can reduce iron and copper ions, and the reduced iron and copper ions reduce hydrogen peroxide, resulting in hydroxyl radicals. In vivo, superoxides can also release iron ions (II) from ferritin. This phenomenon appears after ultraviolet irradiation and is considered to be the action of superoxides produced by ultraviolet radiation.

Herbal tea extract of the present invention was excellent in scavenging activity (SC 50) of the superoxide radical according to the concentration was 1.6 ㎍ / ㎖.

Experimental Example 8: Measurement of collagenase inhibitory ability

Collagen deficiency is one of the causes of skin wrinkles. Collagen is a major protein that makes up the skin dermis and plays a role in maintaining skin structure and elasticity. Collagen is known to decrease the production and increase the decomposition with age to induce depression of the dermal dermal layer to form wrinkles of the skin. In addition, the decomposition of collagen is increased by UV, the cause of photoaging, wrinkles appear. Therefore, the effect of inhibiting collagenase activity of the extract can confirm the effect of skin wrinkle improvement.

According to the concentration of herbal tea extract of the present invention, the activity inhibitory activity (IC50) of collagenase was 1.0 μl / ml.

 Experimental Example 9: Measurement of lipoxygenase inhibition

Lipoxygenase is an oxidation that produces 1,3-cis, trans-diene 5-hydroperoxide by adding molecular oxygen to unsaturated fatty acids with 1,4-cis and cis-pentadiene structures in the molecule, such as linoleic acid, linoleic acid, and arachidonic acid. It is an enzyme involved in the first reaction of leukotrienes biosynthesis from arachidonic acid to various inflammatory and allergic diseases. Therefore, anti-inflammatory effect can be measured by measuring lipoxygenase inhibitory activity using soy lipoxygenase, which is structurally and mechanism-like soy lipoxygenase.

Herbal tea extract of the present invention showed an inhibitory activity of lipoxygenase activity (IC 50) according to the concentration of the extract 18.0 μl / ml.

The cosmetic composition according to the present invention may further contain a medium wavelength ultraviolet absorber, and the medium wavelength ultraviolet absorber may be at least one selected from benzophenone derivatives, paraaminobenzoic acid derivatives, cinnamic acid derivatives, salicylic acid derivatives, and triazine derivatives.

Although the present invention has been described in connection with the above-mentioned preferred embodiment, the scope of the present invention is not limited to the embodiment, various modifications and variations will be possible.

Cosmetics including the herbal tea extract of the present invention through the above examples and experimental examples contain extracts of the main herbal tea components consisting of natural herbal teas such as brown tea, mulberry tea, persimmon leaf tea, cinnamon tea, mugwort tea, chrysanthemum tea, green tea It is to provide a cosmetic composition having excellent skin protection against ultraviolet rays.

Although the present invention has been described in connection with the above-mentioned preferred embodiments, the scope of the present invention is not limited to these embodiments, and the scope of the present invention is defined by the following claims, and equivalent scope of the present invention. It will include various modifications and variations belonging to.

Claims (4)

A cosmetic composition containing a herbal tea extract having a skin protection effect against ultraviolet rays, Skin protection effect against ultraviolet rays, characterized by containing herbal tea extract extracted by low-temperature ultrasonic extraction method consisting of brown root tea, mulberry tea, persimmon leaf tea, cinnamon tea, mugwort tea, chrysanthemum tea, green tea based on 100% by weight of cleaning composition Eggplant cosmetic composition. The method of claim 1, The composition of the herbal tea extract is based on each dry weight 10 ~ 20% by weight, mulberry tea 10 ~ 20% by weight, persimmon leaf tea 10 ~ 20% by weight, cinnamon tea 10 ~ 20% by weight, mugwort tea 10 ~ 20 weight %, Chrysanthemum tea 10 to 30% by weight, green tea 10 to 30% by weight of the cosmetic composition characterized in that mixed. The method of claim 1, Cosmetic composition characterized by further containing a medium wavelength ultraviolet absorber. The method of claim 3, The medium-wavelength ultraviolet absorber is a cosmetic composition, characterized in that at least one selected from benzophenone derivatives, paraamino benzoic acid derivatives, cinnamic acid derivatives, salicylic acid derivatives, triazine derivatives.

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