KR100898308B1 - Cosmetic composition with the effect of calming skins - Google Patents
Cosmetic composition with the effect of calming skins Download PDFInfo
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- KR100898308B1 KR100898308B1 KR1020070064104A KR20070064104A KR100898308B1 KR 100898308 B1 KR100898308 B1 KR 100898308B1 KR 1020070064104 A KR1020070064104 A KR 1020070064104A KR 20070064104 A KR20070064104 A KR 20070064104A KR 100898308 B1 KR100898308 B1 KR 100898308B1
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
본 발명은 피부 진정 효과를 가지는 화장료 조성물에 관한 것으로, 더욱 상세하게는 주요 생약 성분으로 목련, 산다화, 연꽃, 봉선화, 진달래로 구성된 복합 추출물(Phyto Soothing)을 함유하여 피부 진정 효과가 우수한 화장료 조성물을 제공하는 것이다. The present invention relates to a cosmetic composition having a skin soothing effect, and more particularly, to a cosmetic composition having excellent skin soothing effect by containing a complex extract consisting of magnolia, sandflower, lotus, balsam, and azalea as main herbal ingredients. To provide.
피부진정, 화장료, 목련, 산다화 Skin soothing, cosmetics, magnolia, sandalization
Description
본 발명은 피부 진정 효과를 갖는 화장료 조성물에 관한 것으로, 더욱 상세하게는 주요 생약 성분으로 목련, 산다화, 연꽃, 봉선화, 진달래 추출물을 함유함으로써 피부 진정 효과를 제공할 수 있는 화장료 조성물에 관한 것이다. The present invention relates to a cosmetic composition having a skin soothing effect, and more particularly, to a cosmetic composition which can provide a skin soothing effect by containing magnolia, sanda, lotus, balsam, azalea extract as main herbal ingredients.
일반적으로 태양 광선에 포함된 자외선은 그 파장 영역에 따라 장파장, 중파장, 단파장으로 나누어지며, 이들 자외선은 피부에 여러 부작용을 유발하는 것으로 알려져 있다.Generally, ultraviolet rays included in the sun's rays are divided into long, medium, and short wavelengths according to their wavelength ranges. These ultraviolet rays are known to cause various side effects on the skin.
자외선 중의 단파장 자외선은 인체에 매우 유해하나 현재까지는 대기중의 오존층에 흡수되어 지표상에는 거의 도달하지 않으며, 주로 장파장 자외선과 중파장 자외선이 피부에 부작용을 유발하는 것으로, 장파장 자외선은 색소 침착, 광독성, 광알레르기 등을 유발하고, 에너지가 더 큰 중파장 자외선은 홍반, 수포 유발을 비롯한 화상, 피부암, 색소 침착 및 피부 단백질 변성 등을 일으키므로 이들 피부에 조사되는 자외선을 막아주는 것이 피부의 건강에 매우 중요하며, 종래로부터 자외선을 막아주기 위한 여러 가지 자외선 차단제가 개발되어 왔다.Short wavelength ultraviolet rays in ultraviolet light are very harmful to the human body, but until now they are absorbed by the ozone layer in the atmosphere and hardly reach the earth's surface. Medium-wavelength ultraviolet rays, which cause photoallergy and more energy, cause erythema, blistering, burns, skin cancer, pigmentation, and degeneration of skin proteins. Importantly, various sunscreens have been developed to block ultraviolet rays.
종래의 자외선 흡수제로는 벤조페논 유도체, 파라아미노 유도체, 계피산 유도체, 트리아진 유도체 등의 화합물질이 있고, 자외선 산란제로는 이산화티탄, 산화아연 등의 무기 안료가 사용되어 왔는데, 자외선 흡수제는 주로 중파장 자외선 영역의 자외선만을 흡수하며 자체가 화학합성물질이라 피부에 다른 부작용, 즉 자극, 알레르기 등을 유발할 가능성이 많다. 또한 자외선 산란제는 자외선 뿐만 아니라 가시광선까지도 화장료로 사용하였을 때 불투명하며, 피부에 도포시 사용감이 나쁘다고 지적되어 왔다. Conventional ultraviolet absorbers include compounds such as benzophenone derivatives, paraamino derivatives, cinnamic acid derivatives and triazine derivatives, and inorganic pigments such as titanium dioxide and zinc oxide have been used as ultraviolet scatterers. It absorbs only the ultraviolet rays of the intestinal ultraviolet region and is a chemical synthetic substance, which is likely to cause other side effects on the skin, such as irritation and allergy. In addition, UV scattering agent is opaque when used as a cosmetic in addition to ultraviolet light as well as visible light has been pointed out that the feeling is poor when applied to the skin.
한편, 천연물에서 추출 분리한 자외선 흡수 작용을 가지는 물질은 일반적으로 자극이 적고, 항염증, 수렴 작용, 항균 작용과 같은 기타의 약리작용을 가지고 있기 때문에 종래로부터 화장료에 배합하는 자외선 흡수제로서 유망시되어 왔으며, 천연물 중에 함유되어 있는 자외선 흡수물질을 검색, 분리하려는 노력이 시도되어 왔다.On the other hand, a substance having an ultraviolet absorbing action extracted from a natural product generally has a low irritation, and has other pharmacological actions such as anti-inflammatory, astringent, and antimicrobial effects, and thus has been promising as a ultraviolet absorber conventionally incorporated into cosmetics. Efforts have been made to search for and isolate ultraviolet absorbers contained in natural products.
본 발명은 상기와 같은 문제점을 해결하기 위한 것으로서, 이미 알려져 있는 자외선 차단제의 단점을 극복하고 보다 우수한 자외선 차단제를 개발하기 위한 연구의 일환으로 각종 천연물로부터 물 또는 유기용매로 추출한 생약 추출물의 특성을 고려한 결과, 피부 진정 효과를 갖는 화장료 조성물을 개발하기 위해 연구하던중 주요 생약 식물 즉, 목련, 산다화, 연꽃, 봉선화, 진달래 추출물을 함유하여 피부 진정 효과가 우수한 화장료 조성물을 제공하는 것이다. The present invention is to solve the above problems, as a part of the research to overcome the disadvantages of the known sunscreen and to develop a better sunscreen considering the characteristics of the herbal extract extracted with water or organic solvent from various natural products As a result, while researching to develop a cosmetic composition having a skin soothing effect, it contains a main herbal plant, that is, magnolia, sandflower, lotus, balsam, azalea extract to provide a cosmetic composition with excellent skin soothing effect.
이하 본 발명을 보다 상세히 설명한다.Hereinafter, the present invention will be described in more detail.
본 발명은 피부 진정 효과를 갖는 화장료 조성물에 관한 것으로, 더욱 상세하게는 주요 생약 성분으로 목련, 산다화, 연꽃, 봉선화, 진달래 추출물을 함유하여 자외선 흡수 효과를 가지며, 비흡광도가 크며, 화장료용의 각종 기제 및 첨가제, 유기용제 등에 대한 용해성, 친화성 및 안정성이 좋고, 특히 기존의 자외선 차단제와 병용하였을 때 자외선 차단 지수를 현저히 높이는 상승 작용을 제공하는 것이다. The present invention relates to a cosmetic composition having a skin soothing effect, and more particularly, contains a magnolia, an acidification, a lotus, a balsam, an azalea extract as a main herbal ingredient, has an ultraviolet absorption effect, has a large non-absorbance, and various cosmetics. Solubility, affinity, and stability of the base, additives, organic solvents, and the like are good, and in particular, when used in combination with existing sunscreens, it provides a synergistic effect of significantly increasing the sunscreen index.
본 발명에 따르는 조성물에서 각 생약 성분의 조성은 각각의 건조중량을 기준으로 하여 목련 10 ~ 30 중량%, 산다화 10 ~ 30 중량%, 연꽃 10 ~ 30 중량%, 봉선화 10 ~ 30 중량%, 진달래 10 ~ 30 중량%의 비율로 배합하여 사용된다. The composition of each herbal ingredient in the composition according to the present invention is 10-30% by weight, 10-30% by weight, 10-30% by weight, lotus flower 10-30%, balsam 10-30% by weight, azalea 10, based on the respective dry weight. It is used in combination at a ratio of ˜30% by weight.
상기의 배합비로 혼합한 생약 추출물에 1 내지 10배의 증류수를 가하여 100±10℃에서 6시간 3회 반복 추출한 후 여과하고, 감압 농축하여 화장료 제조시 첨가한다.Distilled water of 1 to 10 times was added to the herbal extracts mixed in the above compounding ratio, and extracted three times for 6 hours at 100 ± 10 ° C., filtered, concentrated under reduced pressure, and added to prepare cosmetics.
본 발명에 따른 화장료 조성물은 상기 제조된 생약 추출물을 0.1 ~ 5 중량%로 바람직하게는 1 중량%가 되게 함유하는 것을 특징으로 한다.The cosmetic composition according to the present invention is characterized in that it contains 0.1 to 5% by weight of the prepared herbal extract to preferably 1% by weight.
본 발명에 따른 피부 진정 효과를 가지는 화장료 조성물은 통상의 제형을 가질 수 있으며, 예를 들어 유연화장수, 수렴화장수, 영양화장수, 영양크림, 바디로션, 바디오일, 바디에센스 등으로 제형화될 수 있다. 이들 각 제형의 조성물은 그 제형의 제제화에 필요하고 적절한 각종의 기제와 첨가물을 함유할 수 있으며, 이들 성분의 종류와 양은 당업자에 의해 용이하게 선정될 수 있다. 이하에 피부 진정 효과를 갖는 화장료 조성물의 대표적인 스킨과 로션 조성물을 예를 들어 설명한다.Cosmetic compositions having a skin soothing effect according to the present invention may have a conventional formulation, for example, may be formulated with softening water, astringent makeup, nutrient cosmetics, nutrition cream, body lotion, body oil, body essence and the like. . The composition of each of these formulations may contain a variety of bases and additives necessary for the formulation of the formulation and are suitable, and the types and amounts of these components can be readily selected by those skilled in the art. Below, the typical skin and lotion composition of the cosmetic composition which has a skin calming effect is demonstrated to an example.
또한 본 발명에 따른 피부 진정 효과를 가지는 화장료 조성물은 통상적인 사용방법에 따라 사용될 수 있으며, 사용자의 피부 상태 또는 취향에 따라 그 사용횟수를 달리할 수 있다.In addition, the cosmetic composition having a skin soothing effect according to the present invention may be used according to a conventional method of use, and the number of times of use may vary depending on the skin condition or taste of the user.
이하 본 발명의 실시예를 통하여 본 발명의 피부 진정 효과를 가지는 화장료 조성물을 보다 상세히 설명하지만 본 발명이 이들 실시예에만 국한되는 것은 아니다.Hereinafter, the cosmetic composition having a skin calming effect of the present invention will be described in more detail with reference to examples of the present invention, but the present invention is not limited to these examples.
실시예 1 : 생약 추출물의 제조Example 1 Preparation of Herbal Extracts
생약제 추출물은 건조된 생약제를 분말화하여 사용하였다.The herbal extract was used to powder the dried herbal medicine.
하기 표 1에 나타난 바와 같이 혼합한 생약제에 10배의 증류수를 가하여 100±10℃에서 6시간 3회 반복 추출한 후 여과하고, 감압 농축하여 1g의 생약제 추출물을 획득하였다.10 times distilled water was added to the mixed herbal medicines as shown in Table 1, followed by repeated extraction three times at 100 ± 10 ° C. for 6 hours, followed by filtration and concentration under reduced pressure to obtain 1 g of herbal medicine extract.
실시예 2 : 본 발명에 따른 피부 진정 효과가 있는 스킨 로션의 제조Example 2 Preparation of Skin Lotion with Skin Soothing Effect According to the Present Invention
하기 표 2에 나타난 바와 같은 조성비율로 스킨 로션을 제조하였다. 알콜 부분은 곡정에서 생산하여 78℃ 증류한 알콜에 M-P, tween 20, NP-12의 순서대로 용해시켜 제조하였고, 정제수 부분은 멸균 처리된 정제수에 글리세린, 1,3-BG, DC-193, 히아루론산, 알란토인, 구연산, 구여산소다의 순서대로 용해시켜 제조한 다음 상기 실시예 1에서 제조한 생약제 추출물과 혼합하여 스킨 로션을 제조하였다. A skin lotion was prepared at the composition ratio as shown in Table 2 below. The alcohol part was produced by dissolving in the order of MP, tween 20, NP-12 in alcohol distilled at 78 ° C in the order of grain, and the purified water part was glycerin, 1,3-BG, DC-193, hyaluronic acid in sterilized purified water. Prepared by dissolving in the order of, allantoin, citric acid, sodium citric acid and then mixed with the herbal extracts prepared in Example 1 to prepare a skin lotion.
실시예 3 : 본 발명에 따른 피부 진정 효과가 있는 밀크 로션의 제조Example 3: Preparation of milk lotion having a skin soothing effect according to the present invention
실시예 2와 동일한 방법으로 밀크 로션을 제조하였다.Milk lotion was prepared in the same manner as in Example 2.
실험예 1 : 본 발명에 따른 스킨 로션의 피부 자극성 및 진정 효과 확인Experimental Example 1: Check the skin irritation and calming effect of the skin lotion according to the present invention
건강한 성인 남녀 30명(남자 15명, 여자 15명)의 전박부에 상기 실시예 2에서 제조한 스킨 로션을 일정량(50m/5㎠)씩 도포하고, 그외의 부위를 알루미늄 호일로 차폐하여 30분 후에, 자외선 조사기를 이용하여 장파장 자외선을 10.2J/㎠ 의 용량으로 조사하고 24시간 후에 피부 상태(홍반, 부종, 구진 등)를 관찰하였다. 관찰 결과 피부에 홍반 등의 부작용이 발생되지 않아 상기 스킨 로션은 광독성이 없으며 피부 진정 효과가 있음을 확인할 수 있었다. Apply the skin lotion prepared in Example 2 (50m / 5cm2) to the forearm of 30 healthy males and females (15 males, 15 females) and shield the rest with aluminum foil for 30 minutes. Subsequently, long wavelength ultraviolet rays were irradiated at a dose of 10.2 J / cm 2 using an ultraviolet irradiator, and skin conditions (erythema, edema, papules, etc.) were observed after 24 hours. As a result, skin side effects such as erythema do not occur on the skin, and thus the skin lotion has no phototoxicity and has a skin calming effect.
실험예 2 : 본 발명에 따른 밀크 로션의 피부 자극성 및 진정 효과 확인Experimental Example 2: Confirmation of skin irritation and calming effect of milk lotion according to the present invention
건강한 성인 남녀 30명(남자 15명, 여자 15명)의 전박부에 상기 실시예 3에서 제조한 밀크 로션을 일정량(10m/5㎠)씩 도포하고, 그외의 부위를 알루미늄 호일로 차폐하여 30분 후에, 자외선 조사기를 이용하여 장파장 자외선을 10.2J/㎠ 의 용량으로 조사하고 24시간 후에 피부 상태(홍반, 부종, 구진 등)를 관찰하였다. 관찰 결과 피부에 홍반 등의 부작용이 발생되지 않아 상기 밀크 로션은 광독성이 없으며 피부 진정 효과가 있음을 확인할 수 있었다. Apply the milk lotion prepared in Example 3 (10m / 5cm2) to the forearm of 30 healthy males and females (15 males, 15 females), and cover the rest with aluminum foil for 30 minutes. Subsequently, long wavelength ultraviolet rays were irradiated at a dose of 10.2 J / cm 2 using an ultraviolet irradiator, and skin conditions (erythema, edema, papules, etc.) were observed after 24 hours. As a result, the side effects such as erythema do not occur on the skin, and thus the milk lotion has no phototoxicity and has a skin calming effect.
실험예 3 : 본 발명에 따른 스킨 로션 및 밀크 로션의 피부 안정성 확인 시험Experimental Example 3: Skin stability confirmation test of skin lotion and milk lotion according to the present invention
건강한 성인 남녀 30명(남자 15명, 여자 15명)의 전박부에 상기 실시예 2와 3에서 제조한 스킨 로션 및 밀크 로션을 인체 첩포 시험을 실시하였다. 시험대상자의 전박부를 70% 에탄올로 잘 닦은 다음 그 부위에, 통상의 화장료 기제에 상기 실시예 2와 3에서 제조한 스킨 로션 및 밀크 로션을 20㎕씩 담은 핀 챔버를 점착 테이프를 이용하여 24시간 폐쇄 부착시켰다. 24시간 후에 점착 테이프와 핀 챔버를 제거하고, 가제로 피부에 잔존된 시료를 가볍게 닦아 제거한 뒤에 피부 상태를 관찰하고 다시 24시간 후에 한번 더 관찰하였다. 실험 결과 표 4에 나타난 바와 같이 본 발명에 따른 스킨 로션 및 밀크 로션의 피부 자극성을 확인하기 위한 인체 첩포 시험에서 양성 반응을 보이지 않아 인체 피부에 자극성이 전혀 없는 것으로 확인되었다. The skin patch and milk lotion prepared in Examples 2 and 3 were subjected to a human patch test on the forearm of 30 healthy adult men and women (15 males and 15 females). Wipe the forearm of the subject well with 70% ethanol, and then place a pin chamber containing 20 μl of the skin lotion and milk lotion prepared in Examples 2 and 3 on a conventional cosmetic base using adhesive tape for 24 hours. Closed attachment. After 24 hours, the adhesive tape and the pin chamber were removed, and the sample remaining on the skin with a gauze was lightly removed, and then the skin condition was observed, and again after 24 hours. Experimental results As shown in Table 4, in the human patch test to confirm the skin irritation of the skin lotion and milk lotion according to the present invention did not show a positive response was confirmed that there is no irritation to the human skin.
이상 상기 실시예와 실험예를 통하여 본 발명의 화장료는 천연 생약재인 목련, 산다화, 연꽃, 봉선화, 진달래 추출물에서 유래한 천연 유효 성분을 함유함으로써 피부 진정 효과가 우수한 화장료 조성물을 제공하는 것이다. The cosmetics of the present invention through the above examples and experimental examples are to provide a cosmetic composition with excellent skin soothing effect by containing a natural active ingredient derived from natural herbal medicines such as magnolia, acidification, lotus, balsam, azalea extract.
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