KR100692720B1 - Mri용 망간 조성물 및 그의 이용방법 - Google Patents

Mri용 망간 조성물 및 그의 이용방법 Download PDF

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Publication number
KR100692720B1
KR100692720B1 KR1020017005278A KR20017005278A KR100692720B1 KR 100692720 B1 KR100692720 B1 KR 100692720B1 KR 1020017005278 A KR1020017005278 A KR 1020017005278A KR 20017005278 A KR20017005278 A KR 20017005278A KR 100692720 B1 KR100692720 B1 KR 100692720B1
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manganese
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calcium
gluconate
ions
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Korean (ko)
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KR20010103622A (ko
Inventor
세안피터알.
하니쉬필립피.
베세이아델알.
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이글 비젼 파마시티컬 코포레이션
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
KR1020017005278A 1998-11-02 1999-10-26 Mri용 망간 조성물 및 그의 이용방법 Expired - Fee Related KR100692720B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/184,835 1998-11-02
US09/184,835 US5980863A (en) 1998-11-02 1998-11-02 Manganese compositions and methods for MRI

Publications (2)

Publication Number Publication Date
KR20010103622A KR20010103622A (ko) 2001-11-23
KR100692720B1 true KR100692720B1 (ko) 2007-03-09

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Country Link
US (1) US5980863A (enExample)
EP (1) EP1126785B1 (enExample)
JP (1) JP4763132B2 (enExample)
KR (1) KR100692720B1 (enExample)
CN (1) CN1325286A (enExample)
AT (1) ATE434406T1 (enExample)
AU (1) AU754294B2 (enExample)
CA (1) CA2349342C (enExample)
DE (1) DE69941029D1 (enExample)
NO (1) NO327611B1 (enExample)
NZ (1) NZ511592A (enExample)
WO (1) WO2000025671A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
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DE60316410T2 (de) * 2002-02-05 2008-06-19 Bristol-Myers Squibb Co. N-substituierte 3-hydroxy-4-pyridinone und diese enthaltende pharmazeutika
US6869591B2 (en) * 2002-03-26 2005-03-22 Barnes-Jewish Hospital Paramagnetic particles that provide improved relaxivity
JP4614281B2 (ja) * 2002-12-16 2011-01-19 ジーイー・ヘルスケア・アクスイェ・セルスカプ 磁気共鳴撮像方法並びに該方法に用いられる化合物
US20050106100A1 (en) * 2003-09-03 2005-05-19 Harris Thomas D. Compounds containing matrix metalloproteinase substrates and methods of their use
US20050197614A1 (en) * 2004-03-04 2005-09-08 Wilson Pritchard Occlusive biomedical devices, punctum plugs, and methods of use thereof
JP2006282604A (ja) * 2005-04-01 2006-10-19 Fuji Photo Film Co Ltd 金属キレート構造を有するグリセリンエステル誘導体
JP2009500410A (ja) * 2005-06-30 2009-01-08 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー イメージング剤としてのヒドラジドコンジュゲート
US20080081021A1 (en) * 2006-09-29 2008-04-03 Mehmet Bilgen Manganese-enhanced magnetic resonance imaging of neurons using electrical stimulation
US8414866B2 (en) * 2007-12-17 2013-04-09 Ge Healthcare As Method of magnetic resonance imaging of the heart with paramagnetic MN2+
WO2011003818A2 (en) 2009-07-06 2011-01-13 Cmc Contrast Ab Diagnostic method
CN103656690B (zh) * 2012-09-11 2016-04-27 南京逐陆医药科技有限公司 一种氯化锰口服溶液的制备方法
KR101683635B1 (ko) 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
US10233205B2 (en) 2015-08-07 2019-03-19 Auburn University Magnetic resonance imaging contrast agent capable of detecting hydrogen peroxide and reducing reactive oxygen species
KR102868782B1 (ko) 2018-01-12 2025-10-13 (주)메티메디제약 만성 염증성 질환의 치료 방법
JP2020069470A (ja) * 2018-10-29 2020-05-07 株式会社げんてん本店 リポソームの製造方法、及び、リポソーム含有液の製造方法

Citations (1)

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US5344640A (en) * 1991-10-22 1994-09-06 Mallinckrodt Medical, Inc. Preparation of apatite particles for medical diagnostic imaging

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FR2126134A1 (en) * 1971-02-26 1972-10-06 Ates Ibrahim Cyclophosphamide/magnesium compsns - with enhanced cytostatic activity
US4647447A (en) * 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
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US5082649A (en) * 1987-06-30 1992-01-21 Mallinckrodt Medical, Inc. Method for enhancing the safety of metal-ligand chelates as magnetic resonance imaging agents by addition of calcium ions
US4915933A (en) * 1986-06-26 1990-04-10 The University Of New Mexico Mixed complexes as shift and contrast reagents in NMR imaging and spectroscopy
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US5078986A (en) * 1989-02-15 1992-01-07 Mallinckrodt Medical, Inc. Method for enhancing magnetic resonance imaging using an image altering agent containing an excess of chelating agent
US5143716A (en) * 1991-02-01 1992-09-01 Unger Evan C Phosphorylated sugar alcohols, Mono- and Di-Saccharides as contrast agents for use in magnetic resonance imaging of the gastrointestinal region
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US5250284A (en) * 1991-10-15 1993-10-05 Arnon Krongrad Method for increasing nuclear magnetic resonance signals in living biological tissue using zinc
JP2911674B2 (ja) * 1992-02-20 1999-06-23 明治乳業株式会社 消化管造影用組成物
US5401492A (en) * 1992-12-17 1995-03-28 Sterling Winthrop, Inc. Water insoluble non-magnetic manganese particles as magnetic resonance contract enhancement agents
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AU688565B2 (en) * 1994-08-18 1998-03-12 Nycomed Imaging As Compositions

Patent Citations (1)

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Also Published As

Publication number Publication date
NZ511592A (en) 2002-09-27
AU1808600A (en) 2000-05-22
WO2000025671A9 (en) 2000-10-26
NO327611B1 (no) 2009-08-31
JP4763132B2 (ja) 2011-08-31
CA2349342A1 (en) 2000-05-11
AU754294B2 (en) 2002-11-14
EP1126785A4 (en) 2006-05-17
JP2002528473A (ja) 2002-09-03
ATE434406T1 (de) 2009-07-15
EP1126785A1 (en) 2001-08-29
CN1325286A (zh) 2001-12-05
DE69941029D1 (de) 2009-08-06
NO20011946L (no) 2001-04-19
EP1126785B1 (en) 2009-06-24
CA2349342C (en) 2011-07-12
NO20011946D0 (no) 2001-04-19
US5980863A (en) 1999-11-09
WO2000025671A1 (en) 2000-05-11
KR20010103622A (ko) 2001-11-23

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