KR100576931B1 - 각막을커팅시키기위한개선된자동수술장치 - Google Patents
각막을커팅시키기위한개선된자동수술장치 Download PDFInfo
- Publication number
- KR100576931B1 KR100576931B1 KR1019980706092A KR19980706092A KR100576931B1 KR 100576931 B1 KR100576931 B1 KR 100576931B1 KR 1019980706092 A KR1019980706092 A KR 1019980706092A KR 19980706092 A KR19980706092 A KR 19980706092A KR 100576931 B1 KR100576931 B1 KR 100576931B1
- Authority
- KR
- South Korea
- Prior art keywords
- head assembly
- cutting head
- cutting
- positioning ring
- housing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000005520 cutting process Methods 0.000 title claims abstract description 227
- 210000004087 cornea Anatomy 0.000 title claims abstract description 104
- 230000008878 coupling Effects 0.000 claims abstract description 28
- 238000010168 coupling process Methods 0.000 claims abstract description 28
- 238000005859 coupling reaction Methods 0.000 claims abstract description 28
- 210000001508 eye Anatomy 0.000 claims description 83
- 238000000034 method Methods 0.000 claims description 60
- 210000003128 head Anatomy 0.000 claims description 10
- 230000002093 peripheral effect Effects 0.000 claims description 10
- 230000014759 maintenance of location Effects 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 2
- 230000000670 limiting effect Effects 0.000 claims description 2
- 239000011800 void material Substances 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 description 22
- 210000001519 tissue Anatomy 0.000 description 14
- 210000001525 retina Anatomy 0.000 description 10
- 208000014733 refractive error Diseases 0.000 description 8
- 230000004397 blinking Effects 0.000 description 6
- 208000001491 myopia Diseases 0.000 description 5
- 230000004379 myopia Effects 0.000 description 5
- 230000010355 oscillation Effects 0.000 description 4
- 230000002441 reversible effect Effects 0.000 description 4
- 201000009310 astigmatism Diseases 0.000 description 3
- 210000005252 bulbus oculi Anatomy 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- 206010020675 Hypermetropia Diseases 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 201000006318 hyperopia Diseases 0.000 description 2
- 230000004305 hyperopia Effects 0.000 description 2
- 238000002430 laser surgery Methods 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 210000001747 pupil Anatomy 0.000 description 2
- 238000007634 remodeling Methods 0.000 description 2
- 230000009469 supplementation Effects 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- 125000002066 L-histidyl group Chemical group [H]N1C([H])=NC(C([H])([H])[C@](C(=O)[*])([H])N([H])[H])=C1[H] 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000013532 laser treatment Methods 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000001328 optic nerve Anatomy 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/013—Instruments for compensation of ocular refraction ; Instruments for use in cornea removal, for reshaping or performing incisions in the cornea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F2009/0035—Devices for immobilising a patient's head with respect to the instrument
- A61F2009/0043—Devices for immobilising a patient's head with respect to the instrument by supporting the instrument on the patient's head, e.g. head bands
- A61F2009/0052—Devices for immobilising a patient's head with respect to the instrument by supporting the instrument on the patient's head, e.g. head bands the instrument being supported on the patient's eye
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Robotics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/598,180 US5624456A (en) | 1996-02-07 | 1996-02-07 | Automatic surgical device for cutting a cornea |
| US08/598,180 | 1996-02-07 | ||
| US8/598,180 | 1996-02-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR19990082362A KR19990082362A (ko) | 1999-11-25 |
| KR100576931B1 true KR100576931B1 (ko) | 2006-06-21 |
Family
ID=24394558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019980706092A Expired - Lifetime KR100576931B1 (ko) | 1996-02-07 | 1997-02-06 | 각막을커팅시키기위한개선된자동수술장치 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US5624456A (enExample) |
| EP (2) | EP1438941A3 (enExample) |
| JP (2) | JP4102860B2 (enExample) |
| KR (1) | KR100576931B1 (enExample) |
| CN (2) | CN1951347A (enExample) |
| AT (1) | ATE263533T1 (enExample) |
| AU (1) | AU706115B2 (enExample) |
| BR (1) | BR9707374A (enExample) |
| CA (1) | CA2245495C (enExample) |
| DE (1) | DE69728534T2 (enExample) |
| ES (1) | ES2217390T3 (enExample) |
| WO (1) | WO1997028768A1 (enExample) |
Families Citing this family (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5817115A (en) * | 1995-12-04 | 1998-10-06 | Chiron Vision Corporation | Apparatus for resecting corneal tissue |
| US6258110B1 (en) * | 1996-02-07 | 2001-07-10 | Johann F. Hellenkamp | Positioning assembly for retaining and positioning a cornea |
| US20070244496A1 (en) * | 1996-02-07 | 2007-10-18 | Hellenkamp Johann F | Automatic surgical device and control assembly for cutting a cornea |
| US7166117B2 (en) * | 1996-02-07 | 2007-01-23 | Hellenkamp Johann F | Automatic surgical device and control assembly for cutting a cornea |
| US6051009A (en) * | 1996-02-07 | 2000-04-18 | Hellenkamp; Johann F. | Automatic surgical device for cutting a cornea and a cutting blade assembly and control assembly |
| ES2210596T3 (es) * | 1996-12-23 | 2004-07-01 | Instituto Barraquer De America | Microqueratoma. |
| JP3762056B2 (ja) * | 1997-07-03 | 2006-03-29 | 株式会社ニデック | 角膜手術装置 |
| JPH1199167A (ja) | 1997-07-31 | 1999-04-13 | Nidek Co Ltd | 角膜手術装置 |
| FR2767054B1 (fr) * | 1997-08-05 | 1999-09-10 | Khalil Hanna | Appareil chirurgical pour realiser une decoupe lamellaire de cornee |
| ES2190516T3 (es) * | 1997-08-06 | 2003-08-01 | Sis Ltd Surgical Instr Systems | Microqueratomo para realizar cirugia de la cornea con laser. |
| FR2767677B1 (fr) * | 1997-09-04 | 1999-11-05 | Moria Sa | Microkeratome pour chirurgie optalmologique |
| US6610075B1 (en) * | 1997-10-24 | 2003-08-26 | Becton, Dickenson And Company | Keratome with suspended stabilized blade, improved suction ring with applanator and guided engagement with keratome cutter head, automated translation of the cutter head, and blade insertion tool |
| US6197038B1 (en) * | 1997-11-17 | 2001-03-06 | O'donnell, Jr. Francis E. | Apparatus for lamellar keratoplasty |
| US6228099B1 (en) * | 1997-11-21 | 2001-05-08 | Alexander Dybbs | Ophthalmic surgical system and method |
| US6582445B1 (en) | 1998-03-11 | 2003-06-24 | Visx, Incorporated | Trephine for lamellar keratectomy |
| DE69937515T2 (de) | 1998-03-31 | 2008-09-04 | Nidek Co., Ltd., Gamagori | Chirurgische Vorrichtung für die Hornhaut |
| FR2778569B1 (fr) * | 1998-05-14 | 2000-11-10 | Moria Sa | Tubulure d'aspiration pour anneau support de microkeratome de chirurgie ophtalmologique |
| ES2150863B1 (es) * | 1998-08-03 | 2001-06-16 | Novosalud Sl | Microqueratomo para la diseccion de lamelas de tejido corneal. |
| US6599305B1 (en) | 1998-08-12 | 2003-07-29 | Vladimir Feingold | Intracorneal lens placement method and apparatus |
| US20040059361A1 (en) * | 1998-08-12 | 2004-03-25 | Vladimir Feingold | Keratome |
| US20050049621A1 (en) * | 1998-08-12 | 2005-03-03 | Vladimir Feingold | Intracorneal lens placement method and apparatus |
| US6083236A (en) | 1998-08-12 | 2000-07-04 | Feingold; Vladimir | Keratome method and apparatus |
| US5989272A (en) * | 1998-10-05 | 1999-11-23 | Barron Precision Instruments L.L.C. | Keratome for performing eye surgery and method for using same |
| WO2000052516A2 (en) | 1999-03-01 | 2000-09-08 | Boston Innovative Optics, Inc. | System and method for increasing the depth of focus of the human eye |
| EP1033120B1 (en) | 1999-03-03 | 2005-09-07 | Nidek Co., Ltd. | Corneal Surgical apparatus |
| US6447526B1 (en) | 1999-03-24 | 2002-09-10 | Cesar C. Carriazo | Disposable microkeratome blade housing |
| US6656196B1 (en) | 1999-04-12 | 2003-12-02 | Cesar C. Carriazo | Microkeratome cutting blade and method for performing corneal resections |
| US6296650B1 (en) | 1999-04-12 | 2001-10-02 | Cesar C. Carriazo | Microkeratome |
| US6312403B1 (en) | 1999-08-23 | 2001-11-06 | Luis Antonio Ruiz | Eye dryer, eye dryer system and method of using the same |
| JP2001095833A (ja) | 1999-09-30 | 2001-04-10 | Nidek Co Ltd | 角膜手術装置 |
| US6254619B1 (en) | 1999-12-28 | 2001-07-03 | Antoine Garabet | Microkeratome |
| JP3869607B2 (ja) | 2000-01-06 | 2007-01-17 | 株式会社ニデック | 角膜手術装置 |
| US7090669B2 (en) * | 2000-02-14 | 2006-08-15 | Paul Phillip Van Saarloos | Apparatus and procedure for ultraviolet laser ablation |
| JP2003526418A (ja) * | 2000-03-04 | 2003-09-09 | カタナ テクノロジーズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 固体レーザーを用いた角膜のカスタムレーザー切除 |
| US6540760B2 (en) | 2000-06-23 | 2003-04-01 | Oasis Medical, Inc. | Cutting blade and cutting blade assembly |
| DE60131466T2 (de) * | 2000-09-01 | 2008-09-18 | Alexander Cleveland Dybbs | System für die ophthalmologische chirurgie |
| FR2815247B1 (fr) | 2000-10-12 | 2002-12-20 | Moria Sa | Dispositif de chirurgie corneenne |
| US6554847B2 (en) | 2000-12-15 | 2003-04-29 | Bausch & Lomb Incorporated | Zero compression microkeratome cutting head assembly |
| US20020077640A1 (en) * | 2000-12-18 | 2002-06-20 | Metzger Daniel J. | Tapered microkeratome head |
| AR032840A1 (es) * | 2001-02-23 | 2003-11-26 | Ras Holding Corp | Hoja quirurgica que se usa con un instrumento quirurgico para realizar incisiones en implantes en la esclerotica ocular |
| AU2001259137B2 (en) * | 2001-04-25 | 2005-12-15 | Johann F. Hellenkamp | A positioning assembly for retaining and positioning a cornea |
| US6656197B1 (en) * | 2001-06-28 | 2003-12-02 | Lahaye Leon C. | Multi-function surgical instrument for facilitating ophthalmic laser surgery |
| US6818004B2 (en) * | 2001-10-24 | 2004-11-16 | Cesar C. Carriazo | Aspherical positioning ring |
| DE20122067U1 (de) * | 2001-10-25 | 2004-02-12 | Carl Zeiss Meditec Ag | Schneidvorrichtung |
| US7135028B2 (en) * | 2001-12-12 | 2006-11-14 | Nidek Co., Ltd. | Blade for corneal surgery and corneal surgical apparatus comprising the same |
| US6805698B2 (en) * | 2002-04-03 | 2004-10-19 | Alcon, Inc. | Microkeratome blade |
| EP1581093B1 (en) | 2002-05-20 | 2011-08-03 | Refocus Group, Inc. | System and method for determining a position for a scleral pocket for a scleral prosthesis |
| RU2223078C1 (ru) * | 2002-11-14 | 2004-02-10 | Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" им. акад. С.Н. Федорова | Офтальмологический источник лазерного излучения |
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| US7780689B2 (en) * | 2003-04-07 | 2010-08-24 | Technolas Perfect Vision Gmbh | Bar-link drive system for a microkeratome |
| EP1620049B1 (de) * | 2003-05-02 | 2007-01-10 | Albert Daxer | Vorrichtung zum schneiden der hornhaut eines auges |
| US20110098790A1 (en) * | 2009-10-26 | 2011-04-28 | Albert Daxer | Methods for treating corneal disease |
| US7223275B2 (en) * | 2003-05-27 | 2007-05-29 | Yichieh Shiuey | System for cutting the cornea of an eye |
| US7628810B2 (en) | 2003-05-28 | 2009-12-08 | Acufocus, Inc. | Mask configured to maintain nutrient transport without producing visible diffraction patterns |
| US20050046794A1 (en) | 2003-06-17 | 2005-03-03 | Silvestrini Thomas A. | Method and apparatus for aligning a mask with the visual axis of an eye |
| US7611473B2 (en) * | 2003-09-11 | 2009-11-03 | Ethicon, Inc. | Tissue extraction and maceration device |
| US8034003B2 (en) | 2003-09-11 | 2011-10-11 | Depuy Mitek, Inc. | Tissue extraction and collection device |
| AU2005262335A1 (en) * | 2004-07-01 | 2006-01-19 | Biovision Ag | Intracorneal lens placement method and apparatus |
| DE102005001249A1 (de) * | 2005-01-11 | 2006-07-20 | Carl Zeiss Meditec Ag | Sicherheitsmechanismus für ein Laserbehandlungsgerät |
| US20060206126A1 (en) * | 2005-02-01 | 2006-09-14 | Masahiro Sugimura | Blade for use in corneal surgery and corneal surgical apparatus having the same |
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| AU2007347736A1 (en) * | 2006-10-16 | 2008-09-04 | Alcon Research, Ltd. | Universal rechargeable limited reuse assembly for ophthalmic hand piece |
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| US20080281341A1 (en) * | 2007-05-11 | 2008-11-13 | Ension, Inc. | Apparatus and method for endothelial keratoplasty donor tissue transport and delivery |
| US8992516B2 (en) * | 2007-07-19 | 2015-03-31 | Avedro, Inc. | Eye therapy system |
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| US20090187173A1 (en) * | 2008-01-23 | 2009-07-23 | David Muller | System and method for reshaping an eye feature |
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| CN103405285B (zh) * | 2013-09-03 | 2015-03-25 | 天津开发区合普工贸有限公司 | 一种电动快捷动物眼角膜切割装置 |
| US9943403B2 (en) | 2014-11-19 | 2018-04-17 | Acufocus, Inc. | Fracturable mask for treating presbyopia |
| CN104605975B (zh) * | 2015-02-06 | 2016-08-24 | 邓欣然 | 一种截囊针 |
| ES2972581T3 (es) | 2015-10-05 | 2024-06-13 | Acufocus Inc | Métodos de moldeo de lentes intraoculares |
| CN108431676B (zh) | 2015-11-24 | 2022-01-04 | 阿库福库斯公司 | 具有延伸的焦深的复曲面小孔口人工晶状体 |
| US10639197B2 (en) * | 2017-06-19 | 2020-05-05 | Alcon Inc. | Vitrectomy probe |
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| US10219939B1 (en) * | 2017-10-14 | 2019-03-05 | Samer Jaber Bashir | Surgical ophthalmic intra ocular access tool |
| EP3658006B1 (en) * | 2017-10-27 | 2023-03-22 | Alcon Inc. | Foot pedal controlled oct-display for vitreoretinal surgery |
| EP3790508A4 (en) | 2018-05-09 | 2022-02-09 | AcuFocus, Inc. | INTRAOCULAR IMPLANT WITH REMOVABLE OPTICS |
| DE102018218147B3 (de) | 2018-10-23 | 2020-01-02 | Physik Instrumente (Pi) Gmbh & Co. Kg | Positionierungseinrichtung und Lichtbearbeitungsvorrichtung mit einer solchen Positionierungseinrichtung |
| CN112998942B (zh) * | 2021-02-08 | 2022-03-15 | 青岛大学附属医院 | 一种组合式翼状胬肉的手术切除装置 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3583403A (en) * | 1967-06-27 | 1971-06-08 | Austenal Europa Inc | Dermatome |
| CH620111A5 (enExample) * | 1976-09-17 | 1980-11-14 | Univ Melbourne | |
| US4173980A (en) * | 1977-02-25 | 1979-11-13 | Curtin Brian J | Corneal resurfacing apparatus and method |
| FR2489141A1 (fr) * | 1980-09-03 | 1982-03-05 | Sevifra | Appareil chirurgical pour la decoupe precise de la cornee |
| US4674503A (en) * | 1981-03-05 | 1987-06-23 | Peyman Gholam A | Controlled depth penetrant apparatus and method |
| US4688570A (en) * | 1981-03-09 | 1987-08-25 | The Regents Of The University Of California | Ophthalmologic surgical instrument |
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-
1996
- 1996-02-07 US US08/598,180 patent/US5624456A/en not_active Expired - Lifetime
-
1997
- 1997-02-06 WO PCT/US1997/001666 patent/WO1997028768A1/en not_active Ceased
- 1997-02-06 CN CNA200610092659XA patent/CN1951347A/zh active Pending
- 1997-02-06 EP EP04008267A patent/EP1438941A3/en not_active Withdrawn
- 1997-02-06 AT AT97904186T patent/ATE263533T1/de not_active IP Right Cessation
- 1997-02-06 EP EP97904186A patent/EP0906072B1/en not_active Expired - Lifetime
- 1997-02-06 KR KR1019980706092A patent/KR100576931B1/ko not_active Expired - Lifetime
- 1997-02-06 CA CA2245495A patent/CA2245495C/en not_active Expired - Lifetime
- 1997-02-06 ES ES97904186T patent/ES2217390T3/es not_active Expired - Lifetime
- 1997-02-06 AU AU18543/97A patent/AU706115B2/en not_active Expired
- 1997-02-06 CN CNB971926654A patent/CN1269461C/zh not_active Expired - Lifetime
- 1997-02-06 DE DE69728534T patent/DE69728534T2/de not_active Expired - Lifetime
- 1997-02-06 JP JP51842697A patent/JP4102860B2/ja not_active Expired - Lifetime
- 1997-02-06 BR BR9707374A patent/BR9707374A/pt not_active IP Right Cessation
- 1997-04-29 US US08/840,430 patent/US6296649B1/en not_active Expired - Lifetime
-
2001
- 2001-04-24 US US09/841,165 patent/US20020091401A1/en not_active Abandoned
-
2007
- 2007-03-30 JP JP2007092302A patent/JP4299351B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| BR9707374A (pt) | 1999-04-13 |
| DE69728534D1 (de) | 2004-05-13 |
| EP1438941A3 (en) | 2011-06-01 |
| CN1212612A (zh) | 1999-03-31 |
| JP2007175545A (ja) | 2007-07-12 |
| EP0906072B1 (en) | 2004-04-07 |
| CA2245495C (en) | 2011-03-22 |
| AU1854397A (en) | 1997-08-28 |
| JP4102860B2 (ja) | 2008-06-18 |
| US20020091401A1 (en) | 2002-07-11 |
| ATE263533T1 (de) | 2004-04-15 |
| CA2245495A1 (en) | 1997-08-14 |
| JP4299351B2 (ja) | 2009-07-22 |
| KR19990082362A (ko) | 1999-11-25 |
| AU706115B2 (en) | 1999-06-10 |
| EP0906072A4 (enExample) | 1999-04-07 |
| US6296649B1 (en) | 2001-10-02 |
| EP1438941A2 (en) | 2004-07-21 |
| ES2217390T3 (es) | 2004-11-01 |
| US5624456A (en) | 1997-04-29 |
| JP2000503557A (ja) | 2000-03-28 |
| CN1269461C (zh) | 2006-08-16 |
| DE69728534T2 (de) | 2005-02-24 |
| EP0906072A1 (en) | 1999-04-07 |
| WO1997028768A1 (en) | 1997-08-14 |
| HK1020491A1 (en) | 2000-05-05 |
| CN1951347A (zh) | 2007-04-25 |
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