KR100399541B1 - 3-알콕시카르보닐-티아디아지논유도체 - Google Patents

3-알콕시카르보닐-티아디아지논유도체 Download PDF

Info

Publication number
KR100399541B1
KR100399541B1 KR1019960000414A KR19960000414A KR100399541B1 KR 100399541 B1 KR100399541 B1 KR 100399541B1 KR 1019960000414 A KR1019960000414 A KR 1019960000414A KR 19960000414 A KR19960000414 A KR 19960000414A KR 100399541 B1 KR100399541 B1 KR 100399541B1
Authority
KR
South Korea
Prior art keywords
methyl
thiadiazin
dihydro
tetrahydro
quinolyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019960000414A
Other languages
English (en)
Korean (ko)
Other versions
KR960029331A (ko
Inventor
요나스 로슈스
루에스 잉게
바이에르 노르베르트
밍크 클라우스-오토
Original Assignee
메르크 파텐트 게엠베하
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 메르크 파텐트 게엠베하 filed Critical 메르크 파텐트 게엠베하
Publication of KR960029331A publication Critical patent/KR960029331A/ko
Application granted granted Critical
Publication of KR100399541B1 publication Critical patent/KR100399541B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1019960000414A 1995-01-11 1996-01-11 3-알콕시카르보닐-티아디아지논유도체 Expired - Fee Related KR100399541B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19500558A DE19500558A1 (de) 1995-01-11 1995-01-11 3-Alkoxycarbonyl-thiadiazinone
DEP19500558.9 1995-01-11

Publications (2)

Publication Number Publication Date
KR960029331A KR960029331A (ko) 1996-08-17
KR100399541B1 true KR100399541B1 (ko) 2003-12-31

Family

ID=7751240

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960000414A Expired - Fee Related KR100399541B1 (ko) 1995-01-11 1996-01-11 3-알콕시카르보닐-티아디아지논유도체

Country Status (23)

Country Link
US (1) US5705497A (enExample)
EP (1) EP0721950B1 (enExample)
JP (1) JP4025377B2 (enExample)
KR (1) KR100399541B1 (enExample)
CN (1) CN1055691C (enExample)
AT (1) ATE165828T1 (enExample)
AU (1) AU704493B2 (enExample)
CA (1) CA2166854A1 (enExample)
CZ (1) CZ292094B6 (enExample)
DE (2) DE19500558A1 (enExample)
DK (1) DK0721950T3 (enExample)
ES (1) ES2120251T3 (enExample)
GR (1) GR3027566T3 (enExample)
HU (1) HUP9600061A3 (enExample)
MX (1) MX9600165A (enExample)
NO (1) NO306300B1 (enExample)
PL (1) PL183011B1 (enExample)
RU (1) RU2162087C2 (enExample)
SI (1) SI0721950T1 (enExample)
SK (1) SK280532B6 (enExample)
TW (1) TW407157B (enExample)
UA (1) UA44249C2 (enExample)
ZA (1) ZA96177B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
DE19929785A1 (de) 1999-06-29 2001-01-04 Bayer Ag Tetrahydrochinolinyl-6-methyldihydrothiadiazinon-Derivate und ihre Verwendung
RU2395508C1 (ru) * 2006-05-24 2010-07-27 Лейбниц Инститьют Фор Нэчрал Продакт Рисерч Энд Инфекшн Байолоджи Е.В. Ганс-Кнёль-Институт (Хки) Новые производные бензотиазинона и их применение в качестве антибактериальных средств
WO2016023927A1 (en) * 2014-08-15 2016-02-18 F. Hoffmann-La Roche Ag 2,2,2-trifluoroethyl-thiadiazines
CN112500353B (zh) * 2020-12-08 2022-11-25 北京晨光同创医药研究院有限公司 一种左西孟旦的前药化合物、制备方法及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU614965B2 (en) * 1987-06-06 1991-09-19 Merck Patent Gesellschaft Mit Beschrankter Haftung Thiadiazinones
GB8901836D0 (en) * 1989-01-27 1989-03-15 Sobio Lab Compounds
SU1648949A1 (ru) * 1989-04-25 1991-05-15 Ленинградский Технологический Институт Им.Ленсовета Способ получени 2,4,5-замещенных 4Н-1,3,4-тиадиазинов
DE4041074A1 (de) * 1990-12-21 1992-06-25 Merck Patent Gmbh Thiadiazinonderivate
DE4129062A1 (de) * 1991-09-02 1993-03-04 Merck Patent Gmbh Verfahren zur enantiomerentrennung von 5-hetaryl-1,3,4-thiadiazinonen
DE4134893A1 (de) * 1991-10-23 1993-04-29 Merck Patent Gmbh Thiadiazinone
DE4223537A1 (de) * 1992-07-17 1994-01-20 Merck Patent Gmbh Thiadiazinone
DE4310699A1 (de) * 1993-04-01 1994-10-06 Merck Patent Gmbh Thiadiazinone

Also Published As

Publication number Publication date
RU2162087C2 (ru) 2001-01-20
AU704493B2 (en) 1999-04-22
DK0721950T3 (da) 1999-02-15
EP0721950B1 (de) 1998-05-06
NO960112D0 (no) 1996-01-10
NO306300B1 (no) 1999-10-18
MX9600165A (es) 1997-01-31
SK280532B6 (sk) 2000-03-13
JP4025377B2 (ja) 2007-12-19
CZ292094B6 (cs) 2003-07-16
HUP9600061A2 (en) 1997-10-28
CZ8096A3 (en) 1996-07-17
PL312240A1 (en) 1996-07-22
US5705497A (en) 1998-01-06
SK165295A3 (en) 1996-08-07
GR3027566T3 (en) 1998-11-30
EP0721950A2 (de) 1996-07-17
JPH08253478A (ja) 1996-10-01
CA2166854A1 (en) 1996-07-12
HUP9600061A3 (en) 1998-04-28
UA44249C2 (uk) 2002-02-15
ZA96177B (en) 1996-07-30
KR960029331A (ko) 1996-08-17
ATE165828T1 (de) 1998-05-15
DE19500558A1 (de) 1996-07-18
SI0721950T1 (en) 1998-10-31
ES2120251T3 (es) 1998-10-16
TW407157B (en) 2000-10-01
CN1055691C (zh) 2000-08-23
AU4082696A (en) 1996-07-18
DE59600173D1 (de) 1998-06-10
PL183011B1 (pl) 2002-05-31
EP0721950A3 (enExample) 1996-07-24
CN1135484A (zh) 1996-11-13
HK1010194A1 (en) 1999-06-17
NO960112L (no) 1996-07-12

Similar Documents

Publication Publication Date Title
US4916128A (en) Thiadiazinones
FI93356C (fi) Menetelmä terapeuttisesti käyttökelpoisten heterosyklisten yhdisteiden valmistamiseksi
WO2003080581A1 (en) Phenanthridinones as parp inhibitors
JPH0717633B2 (ja) ヘテロアリールピペラジン抗精神病薬
KR20000016151A (ko) 벤족사지논 도파민 d4 수용체 길항제
KR100399541B1 (ko) 3-알콕시카르보닐-티아디아지논유도체
CA2155758A1 (en) Heteroaromatic compounds with antipsychotic activity
US4584297A (en) Pyrrolo[1,2-c]-1,3-thiazines
AU709133B2 (en) Benzoxazepine derivatives, salts thereof, and drugs containing the same
CA2220140C (en) (2-morpholinylmethyl)benzamide derivatives
US5137885A (en) Thiadiazinones
US4567191A (en) Amino-phenyl-thiadiazoledioxides as gastric secretion inhibitors
EP0753514A1 (en) Alkylenediamine derivative
US3478022A (en) 4-substituted aminopropyl-4h-thieno (2,3-b)(1,4)benzothiazines
JPH01238529A (ja) 骨粗鬆症予防治療剤
HK1010194B (en) 3-alkoxycarbonyl-thiadiazinones cardioactives

Legal Events

Date Code Title Description
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

FPAY Annual fee payment

Payment date: 20060908

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20070917

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20070917

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000