KR100382219B1 - 간 종양 치료용 조성물 - Google Patents

간 종양 치료용 조성물 Download PDF

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Publication number
KR100382219B1
KR100382219B1 KR10-1999-7011663A KR19997011663A KR100382219B1 KR 100382219 B1 KR100382219 B1 KR 100382219B1 KR 19997011663 A KR19997011663 A KR 19997011663A KR 100382219 B1 KR100382219 B1 KR 100382219B1
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KR
South Korea
Prior art keywords
composition
liver
cancer
vitamin
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR10-1999-7011663A
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English (en)
Korean (ko)
Other versions
KR20010013651A (ko
Inventor
모리스데이비드로손
Original Assignee
엠알씨 홀딩즈 피티와이 리미티드
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Application filed by 엠알씨 홀딩즈 피티와이 리미티드 filed Critical 엠알씨 홀딩즈 피티와이 리미티드
Publication of KR20010013651A publication Critical patent/KR20010013651A/ko
Application granted granted Critical
Publication of KR100382219B1 publication Critical patent/KR100382219B1/ko
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR10-1999-7011663A 1997-06-10 1998-06-10 간 종양 치료용 조성물 Expired - Fee Related KR100382219B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPO7270A AUPO727097A0 (en) 1997-06-10 1997-06-10 Method of treatment of hepatoma and pharmaceutical compositions for use therein
AUPO7270 1997-06-10

Publications (2)

Publication Number Publication Date
KR20010013651A KR20010013651A (ko) 2001-02-26
KR100382219B1 true KR100382219B1 (ko) 2003-04-26

Family

ID=3801562

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-1999-7011663A Expired - Fee Related KR100382219B1 (ko) 1997-06-10 1998-06-10 간 종양 치료용 조성물

Country Status (8)

Country Link
US (1) US6486144B1 (enExample)
EP (1) EP1003523A4 (enExample)
JP (1) JP2002504100A (enExample)
KR (1) KR100382219B1 (enExample)
CN (1) CN1154497C (enExample)
AU (1) AUPO727097A0 (enExample)
WO (1) WO1998056387A1 (enExample)
ZA (1) ZA985028B (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6538037B2 (en) 1991-01-08 2003-03-25 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US6087350A (en) 1997-08-29 2000-07-11 University Of Pittsburgh Of The Commonwealth System Of Higher Education Use of pretreatment chemicals to enhance efficacy of cytotoxic agents
AU765846B2 (en) * 1998-05-04 2003-10-02 Mrc Holdings Pty Limited Pharmaceutical composition
AUPP332898A0 (en) * 1998-05-04 1998-05-28 Unisearch Limited Pharmaceutical composition
US20030031670A1 (en) * 1999-11-08 2003-02-13 Jack R. Wands Diagnosis and treatment of malignant neoplasms
WO2001034199A2 (en) * 1999-11-11 2001-05-17 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
DE10032587A1 (de) * 2000-07-05 2002-01-17 Bayer Ag 4-Alkoxy-cyclohexan-1-amino-carbonsäureester und Verfahren zu ihrer Herstellung
AU781168B2 (en) 2001-01-26 2005-05-12 Pfizer Products Inc. Method of treating certain cancers using an estrogen agonist/antagonist
US20050038022A1 (en) * 2001-03-26 2005-02-17 Unisearch Limited Method for treatment of cancer and compositions for use therein
JP2004026811A (ja) * 2002-04-30 2004-01-29 Kiyoshi Hashizume ビタミンｄ３誘導体を含有する抗癌作用を増強させるための薬剤
AU2002330482A1 (en) 2002-09-04 2004-03-29 Perseus Proteomics Inc. Method of diagnosing cancer by detecting gpc3
WO2004047673A2 (en) * 2002-11-21 2004-06-10 Novacea, Inc. Treatment of liver disease with active vitamin d compounds
WO2005027922A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. 2-alkylidene-19-nor-vitamin d derivatives for the treatment of hypogonadism or andropause
WO2005027916A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and aromatase inhibitors
CA2539361A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and an estrogen agonist/antagonist
WO2005027918A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a cyclooxgenase-2 inhibitor
WO2005027928A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. 2-alkylidene-19-nor-vit amin d derivatives for the treatment of hypocalcemic tetany or hyproparathyroidism
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
JP4248544B2 (ja) * 2005-12-19 2009-04-02 株式会社椿本チエイン 伝動装置用可動ガイド
AU2010282731C1 (en) * 2009-08-14 2016-04-21 Berg Llc Vitamin D3 and analogs thereof for treating alopecia
EP2988752A4 (en) 2013-04-24 2017-01-18 Salk Institute for Biological Studies Vitamin d receptor/smad genomic circuit gates fibrotic response
CN105451818A (zh) * 2013-06-05 2016-03-30 萨克生物研究学院 治疗涉及cxcl12活性的疾病的维生素d受体激动剂
JP2016124818A (ja) * 2014-12-26 2016-07-11 日本化薬株式会社 転移性肝癌治療薬及び転移性肝癌の治療方法
WO2016167977A1 (en) 2015-04-14 2016-10-20 Mayo Foundation For Medical Education And Research Methods and materials for delivering agents to liver tissue
WO2019023149A1 (en) 2017-07-24 2019-01-31 Salk Institute For Biological Studies USE OF BROMODOMAIN-CONTAINING PROTEIN-9 ANTAGONISTS IN ASSOCIATION WITH VITAMIN D RECEPTOR AGONISTS IN THE TREATMENT OF DIABETES
CN116059364B (zh) * 2021-11-04 2025-07-11 上海健康医学院 Dhcr7下调剂在减弱酒精诱导的肝脏肿瘤中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0296800B1 (en) * 1987-06-23 1991-10-16 Yamanouchi Pharmaceutical Co. Ltd. Vitamin d3 derivatives
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
US5798345A (en) 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
DK0707566T3 (da) * 1993-07-09 2000-09-04 Theramex Hidtil ukendte strukturelle analoger til vitamin D
US5856189A (en) * 1997-01-07 1999-01-05 The Regents Of The University Of Michigan Cell culture model for drug bioavailability

Also Published As

Publication number Publication date
ZA985028B (en) 1999-01-25
AUPO727097A0 (en) 1997-07-03
US6486144B1 (en) 2002-11-26
CN1261800A (zh) 2000-08-02
HK1030144A1 (en) 2001-04-27
JP2002504100A (ja) 2002-02-05
EP1003523A4 (en) 2001-08-22
EP1003523A1 (en) 2000-05-31
WO1998056387A1 (en) 1998-12-17
KR20010013651A (ko) 2001-02-26
CN1154497C (zh) 2004-06-23

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