JP2002504100A - 肝腫瘍の治療方法およびそれに使用するための医薬組成物 - Google Patents

肝腫瘍の治療方法およびそれに使用するための医薬組成物

Info

Publication number
JP2002504100A
JP2002504100A JP50114299A JP50114299A JP2002504100A JP 2002504100 A JP2002504100 A JP 2002504100A JP 50114299 A JP50114299 A JP 50114299A JP 50114299 A JP50114299 A JP 50114299A JP 2002504100 A JP2002504100 A JP 2002504100A
Authority
JP
Japan
Prior art keywords
vitamin
cancer
compound
liver
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP50114299A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002504100A5 (enExample
Inventor
モーリス，デイヴィッド，ローソン
Original Assignee
エムアールシー ホールディングス ピーティーワイ リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エムアールシー ホールディングス ピーティーワイ リミテッド filed Critical エムアールシー ホールディングス ピーティーワイ リミテッド
Publication of JP2002504100A publication Critical patent/JP2002504100A/ja
Publication of JP2002504100A5 publication Critical patent/JP2002504100A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP50114299A 1997-06-10 1998-06-10 肝腫瘍の治療方法およびそれに使用するための医薬組成物 Withdrawn JP2002504100A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPO7270A AUPO727097A0 (en) 1997-06-10 1997-06-10 Method of treatment of hepatoma and pharmaceutical compositions for use therein
AU7270 1997-06-10
PCT/AU1998/000440 WO1998056387A1 (en) 1997-06-10 1998-06-10 Method of treatment of liver tumours and pharmaceutical compositions for use therein

Publications (2)

Publication Number Publication Date
JP2002504100A true JP2002504100A (ja) 2002-02-05
JP2002504100A5 JP2002504100A5 (enExample) 2005-12-22

Family

ID=3801562

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50114299A Withdrawn JP2002504100A (ja) 1997-06-10 1998-06-10 肝腫瘍の治療方法およびそれに使用するための医薬組成物

Country Status (8)

Country Link
US (1) US6486144B1 (enExample)
EP (1) EP1003523A4 (enExample)
JP (1) JP2002504100A (enExample)
KR (1) KR100382219B1 (enExample)
CN (1) CN1154497C (enExample)
AU (1) AUPO727097A0 (enExample)
WO (1) WO1998056387A1 (enExample)
ZA (1) ZA985028B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007505881A (ja) * 2003-09-19 2007-03-15 ファイザー・プロダクツ・インク ２−アルキリデン−１９−ノル−ビタミンｄ誘導体およびエストロゲンアゴニスト／アンタゴニストの組合せを含む医薬組成物および方法
JP2016124818A (ja) * 2014-12-26 2016-07-11 日本化薬株式会社 転移性肝癌治療薬及び転移性肝癌の治療方法

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6538037B2 (en) 1991-01-08 2003-03-25 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US6087350A (en) 1997-08-29 2000-07-11 University Of Pittsburgh Of The Commonwealth System Of Higher Education Use of pretreatment chemicals to enhance efficacy of cytotoxic agents
AUPP332898A0 (en) * 1998-05-04 1998-05-28 Unisearch Limited Pharmaceutical composition
AU765846B2 (en) * 1998-05-04 2003-10-02 Mrc Holdings Pty Limited Pharmaceutical composition
US20030031670A1 (en) * 1999-11-08 2003-02-13 Jack R. Wands Diagnosis and treatment of malignant neoplasms
AU1917101A (en) * 1999-11-11 2001-06-06 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
DE10032587A1 (de) * 2000-07-05 2002-01-17 Bayer Ag 4-Alkoxy-cyclohexan-1-amino-carbonsäureester und Verfahren zu ihrer Herstellung
AU781168B2 (en) * 2001-01-26 2005-05-12 Pfizer Products Inc. Method of treating certain cancers using an estrogen agonist/antagonist
EP1379242B1 (en) * 2001-03-26 2012-08-15 Newsouth Innovations Pty Limited Method for treatment of cancer and compositions for use therein
JP2004026811A (ja) * 2002-04-30 2004-01-29 Kiyoshi Hashizume ビタミンｄ３誘導体を含有する抗癌作用を増強させるための薬剤
AU2002330482A1 (en) 2002-09-04 2004-03-29 Perseus Proteomics Inc. Method of diagnosing cancer by detecting gpc3
WO2004047673A2 (en) * 2002-11-21 2004-06-10 Novacea, Inc. Treatment of liver disease with active vitamin d compounds
WO2005027922A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. 2-alkylidene-19-nor-vitamin d derivatives for the treatment of hypogonadism or andropause
WO2005027916A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and aromatase inhibitors
WO2005027918A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a cyclooxgenase-2 inhibitor
WO2005027928A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. 2-alkylidene-19-nor-vit amin d derivatives for the treatment of hypocalcemic tetany or hyproparathyroidism
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
JP4248544B2 (ja) * 2005-12-19 2009-04-02 株式会社椿本チエイン 伝動装置用可動ガイド
MX366076B (es) * 2009-08-14 2019-06-27 Berg Llc Vitamina d3 y analogos de la misma para tratar alopecia.
AU2014257051A1 (en) 2013-04-24 2015-11-19 Salk Institute For Biological Studies Vitamin D receptor/SMAD genomic circuit gates fibrotic response
BR112015030518A2 (pt) * 2013-06-05 2017-08-29 Salk Inst For Biological Studi Composição farmacêutica, uso de um ou mais agonistas do receptor da vitamina d (vdr), e, método para a redução da atividade biológica do ligante 12 do motivo c-x-c (cxcl12)
WO2016167977A1 (en) 2015-04-14 2016-10-20 Mayo Foundation For Medical Education And Research Methods and materials for delivering agents to liver tissue
WO2019023149A1 (en) 2017-07-24 2019-01-31 Salk Institute For Biological Studies USE OF BROMODOMAIN-CONTAINING PROTEIN-9 ANTAGONISTS IN ASSOCIATION WITH VITAMIN D RECEPTOR AGONISTS IN THE TREATMENT OF DIABETES
CN116059364B (zh) * 2021-11-04 2025-07-11 上海健康医学院 Dhcr7下调剂在减弱酒精诱导的肝脏肿瘤中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0296800B1 (en) 1987-06-23 1991-10-16 Yamanouchi Pharmaceutical Co. Ltd. Vitamin d3 derivatives
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
US5798345A (en) * 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
AU699200B2 (en) * 1993-07-09 1998-11-26 Roger Bouillon Novel structural analogues of vitamin D
US5856189A (en) * 1997-01-07 1999-01-05 The Regents Of The University Of Michigan Cell culture model for drug bioavailability

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007505881A (ja) * 2003-09-19 2007-03-15 ファイザー・プロダクツ・インク ２−アルキリデン−１９−ノル−ビタミンｄ誘導体およびエストロゲンアゴニスト／アンタゴニストの組合せを含む医薬組成物および方法
JP2016124818A (ja) * 2014-12-26 2016-07-11 日本化薬株式会社 転移性肝癌治療薬及び転移性肝癌の治療方法

Also Published As

Publication number Publication date
HK1030144A1 (en) 2001-04-27
ZA985028B (en) 1999-01-25
CN1261800A (zh) 2000-08-02
EP1003523A4 (en) 2001-08-22
CN1154497C (zh) 2004-06-23
AUPO727097A0 (en) 1997-07-03
KR100382219B1 (ko) 2003-04-26
US6486144B1 (en) 2002-11-26
EP1003523A1 (en) 2000-05-31
KR20010013651A (ko) 2001-02-26
WO1998056387A1 (en) 1998-12-17

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