KR100376306B1 - Healthy food for promoting the circuration of the blood - Google Patents

Abstract

The present invention relates to a health food composition for promoting blood circulation, 9% by weight of wolfberry, 9% by weight of deer antler, 9% by weight of walnut, 9% by weight of cornus oil, 8% by weight of corn, 8% by weight of white horse, 8% by weight of lioness 8 Consisting of 8% by weight, 8% by weight of acupuncture, 8% by weight of neck, 8% by weight of deficiency, 8% by weight of bokbunja has an excellent effect on the treatment of headache due to blood circulation, arteriosclerosis, and blood circulation disorder.

Description

Healthy food for promoting the circuration of the blood}

The present invention relates to a health food composition for promoting blood circulation. More specifically, it relates to a health food composition having excellent palatability and effective in promoting blood circulation by preparing a mixture of goji berry, antler, kwak, kaleun, cornus, white horse, sine, hawthorn, acupuncture, cedar, blame, bokbunja .

With the diversification of means for exchanging information and filing documents, office automation equipment (OA) has become widespread in offices and homes. OA devices generally require a posture that lifts the upper arm away from the user's body during work, so muscle stiffness occurs as the user operates the office equipment for a relatively long time, resulting in stiffness in certain areas such as arms, legs, back and waist. Cause stiffness. In general, muscle stiffness can be easily eased by massaging the stiffness. However, when operating the OA every day, once the stiffness occurs, it does not easily disappear. In addition to the operation of the OA, stiffness can be caused by factors such as physical exercise, physical labor, improper posture, and mental stress, cervical spondylosis, chest exit syndrome, hypertension, stable fatigue, and autonomy. It may also be caused by various diseases such as dystonia and menopausal disorders. Depending on the symptoms of stiffness, unusual mild pain and discomfort persist for a relatively long period of time, in some cases accompanied by headaches and / or vomiting.

The circulation of blood circulates our bodies along the blood vessels around the heart, supplying oxygen to the tissues of the body, releasing carbon dioxide, nutrients, and metabolites. The endocrine gland carries hormones to regulate the function of specific organs, and to carry out other functions such as controlling pathogens, controlling body temperature, controlling osmotic pressure, and controlling water.

Blood vessels consist of camellia, capillaries and veins. Arteries are the outer membrane consisting of external elastic sun board and connective tissue, the mesothelial membrane with a lot of smooth muscles, containing a number of elastic fibers, the innermost endothelial cells, and the connective tissue and elastic fibers surrounding them. Consists of Capillary vessels are small arteries and small veins that are connected in a net shape and are thinly shaped with a diameter of 0.008 to 0.02 mm, and red blood cells pass through 1 to 2 lines and are not visible to the naked eye. And nutrients are sent into the tissue and the CO ₂ and waste products produced by the tissue enter the blood vessels. The vein's outer membrane is relatively thick, the inner and middle membranes are thin, there is no pressure, and the blood flow is weak compared to other blood vessels.

Blood circulation disorder refers to blood vessels that lose their elasticity, cholesterol is deposited on the inner wall, and the lumen of the blood vessels is narrowed, resulting in poor blood circulation.

Stroke (Middle Wind, Wind), the most common circulatory disease, is the bursting of cerebrovascular vessels or clogging with blood clots or fat. Stroke is one of the three leading causes of death among Koreans, along with cancer and heart disease. Stroke is a hemorrhagic stroke caused by the rupture of the cerebral artery wall due to pressure and the formation of hematoma inside the brain tissue to compress the surrounding brain tissue, and part of the cerebral artery is narrowed or blocked, and oxygen and nutrients are supplied through the artery, leading to necrosis of the brain tissue. There are two types of ischemic stroke. Hemorrhagic stroke is further classified into two categories: cerebral hemorrhage and subarachnoid hemorrhage. Ischemic stroke is further classified as cerebral infarction and transient cerebral ischemic attack.

The more common causes of cerebral hemorrhage are hypertension and arteriosclerosis. Hypertension refers to a disease in which systolic blood pressure is more than 140 or diastolic blood pressure is more than 90. Mild hypertension when diastolic blood pressure is 90 to 104, severe hypertension when 105 to 110 is classified as severe hypertension. Ninety percent of all patients with hypertension are primary (primary, primary) hypertension with no known cause, and those with clear cause are secondary (secondary) hypertension. Blood pressure increases with age and is associated with genetic predispositions, hastening personality, obesity, high salt intake, mental stress, smoking, drinking, kidney disease, pheochromocytoma, the use of oral contraceptives, and primary hyperaldosterolemia. Hypertension develops.

Atherosclerosis is called arteriosclerosis, which hardens the arterial wall, reduces elasticity, pinches fat on the inner surface, and causes abnormal tissue to proliferate and narrow the inner diameter. Some of the arteriosclerosis is an aging phenomenon, the older the frequency of arteriosclerosis disease, the more the various organs are invaded at the same time, and this phenomenon occurs in the cerebrovascular stroke. In addition, heart disease and diabetes are also circulatory diseases that are closely related to hypertension and arteriosclerosis.

The mechanism of occurrence of stiffness is not clear yet, but excessive stimulation of the nerves, muscle fatigue and autonomic dystonia causes excessive vascular contraction, blood circulation disorders in the muscles, and hyperemia, which causes unusual stiffness. Therefore, it is effective to improve blood circulation to eliminate muscle stiffness. Treatment methods such as massage, warmth therapy, poultice use, electrical stimulation and drug administration are difficult to obtain the effects of the disturbance, or some of them are complicated because they have to go to the hospital for professional treatment.

The present inventors focused on food research that can promote blood circulation, and promote blood circulation by ingesting natural herbal medicines such as goji berry, deer antler, kwak hyang, brown root, cornus, white horse, sine, hawthorn, acupuncture, wood fragrance, glitches, bokbunja It has been found that the effect can be obtained and the present invention has been completed.

Accordingly, an object of the present invention is to provide a health food composition excellent in blood circulation promoting effect.

The above object of the present invention is natural herbs 9% by weight, antler 9% by weight, balsam 9% by weight, brown root 9%, cornus 8% by weight, white horse 8% by weight, 8% by weight sasa, 8% by weight of lioness, aroma 8 To prepare a health food composition for promoting blood circulation by mixing in weight%, neck weight 8% by weight, 8% by weight deflector, 8% by weight bokbunja, animal experiments using the composition to promote blood circulation, inhibit arteriosclerosis and pain relief Achieved by measuring effect.

Hereinafter, the specific configuration and effects of the present invention will be described with reference to examples, but the selection of food types and the change in composition ratio may deteriorate the effects of health foods and intentionally and intentionally change the scope of rights among those skilled in the art. Of course, such a change in numerical range is within the scope of the present invention.

According to a preferred embodiment of the present invention, 9% by weight of wolfberry, 9% by weight of deer antler, 9% by weight of balsam, 9% by weight of brown root, 8% by weight of cornus oil, 8% by weight of white horse, 8% by weight of hawthorn, 8% by weight of hawthorn, aroma 8 The powder is processed by pulverizing finely divided by weight, 8% by weight of wood, 8% by weight of deficiency, and 8% by weight of bokbunja.

Gojija (Lycinm chinense Miller) is the fruit of the Goji berry, vitamin 0.1%, carotenoids zeaxanthin, biologically active scopoletin, and the pisalien from the fruit peel. Goji is a blood pressure lowering action, anti-interstitial action, liver function protection action to prevent and treat atherosclerosis, as a medicine, inflammatory drugs, heat lowering drugs used in pulmonary tuberculosis, diabetes. In motion therapy, the fruit is used as a supplement to lower back pain, helplessness, dizziness, head pain, and small meals. .

Cornus (Macrocarpium officinale Sieb. Et Zucc.) Is a fruit bark of the hawthorn tree, which includes crystalline organic acids, glutinous assets, malic acid, and grape acids, and the fruit shells include iridonide glycosides such as moronisides and loganins. In motion therapy, nourishment tonic and astringents are used to see the kidneys, and when sweating frequently and urine comes out little by little, it is used when the back pain and the moon are uneven.

Deer antler is an unhorned shell of a deer belonging to the family Cornu cervi, which is one of the most widely used herbal medicines with ginseng. Deer Antler contains components such as free amino acid, hexosamin, uronic acid, sialic acid, hypoxanthine, estrone, estradiol receptor, and the like. Deer Antler is tonic, growth. It has various effects such as development promotion, hematopoiesis, nervous breakdown treatment, heart failure treatment, hypertrophy of five intestines, etc. , Fatigue recovery, physical resistance enhancement, psoriasis anesthesia effect.

Called Agastache rugosa (Fisher et Meyer) O. Kuntze, the perennial herb is 1-1.5m high, essential oil is about 0.3% for outpost, 0.2-2.3% for leaves, 5% for flowers, 0.1% on the stem. The main components of essential oils are methylcarbigol, anisealdehyde, anetol, d-limonene, sesquiterpene, α-pinene, β-pinene, α-limonene, oxanone, P-chimol, linalol, and acachettin as flavonoid , Tilianin, linarin, and agathacoside were isolated. In motion therapy, it is used for cold, head pain and vomiting diarrhea when eating or eating heat with dry stomach medicine, old wind medicine, digestive medicine, heat lowering medicine. It is also rarely used for the treatment of cortical diseases and tumors.

White horse is a natural horse chestnut and nourish each other. It is a medicinal medicine for the treatment of epilepsy, stroke, game, headache, tonic and neurological diseases in Chinese medicine. P-hydroxybenzyl alcohol, its glycosides, gastrin, P-hydroxybenzylaldehyde, etc. are separated from the roots, and dizziness, nausea, cramps, nerve pain, cramps, and nerve disorders in tonic, sedative, and antifungal drugs in motion therapy. When you can not speak, it is used for cramps and paralysis of the limbs and peripheral neuropathy. Words have been said to strengthen the nerves, look at the blood and blacken the head. It is also used for urinary tract drugs, other diabetes, high blood pressure, sexual dysfunction, and physical fatigue. Especially used for cramps in children.

Sine, a fruit of the perennial Amomum xanthioides Wallich., Which has a height of 1.3 to 2 m, uses 2 to 3 g at one time when diarrhea vomits while the stomach is sore, swollen, and eaten without falling down. .

The hawthorn is diuretic because it contains quercetin and oleanoic acid like quince, and it contains vitamin B, C, carotene and chlorogenic acid, which is effective for postpartum abdominal pain, hangover, dryness, indigestion and chronic diarrhea. It is also effective in controlling gastrointestinal activity and treating indigestion.

Aquillaria Agallocha Roxburgh is a 30 m high evergreen tree with no resin in the wood of the plant, but when wounded or rotted, it forms a resin that protects the wound. This type of incense, submerged incense (Lignum Aloes) is to remove the resin-free parts by cutting the resin-like wood in the soil or to naturally rot. Saponification of the fragrance with alkali followed by steam distillation yields an essential oil of 13%. In motion therapy, you can use 1.5 to 3 grams at one time when you are nauseous and vomiting, when your stomach hurts and asthma. The bark is used as a directional dry wind.

Mokhyang (Inula Helenium L.) is a perennial herb that grows from 50 to 150 centimeters in height and contains 1 to 5 percent of essential oils in the stem and roots. When this essential oil is cooled, crystals are called helenin. In addition to helenin, essential oils include triterpene alcohol, dimiradienylacetate C ₃₂ H ₅₂ O ₂ , small amounts of allantol C ₁₅ H ₂₃ O ₂ and proazulene. Roots include inulin, pseudoinulin, inulinen, saponin, bitter substances, pigments, and fuco alkaloids. Anantol is in the fresh root. In motion therapy, sputum, dry stomach, urinary medicine, and sweating medicine are used for various respiratory diseases such as upper catarrhal, bronchitis, and pulmonary tuberculosis. .

Puerariae Radix is a root of kudzu (Pueraria lobata Ohwi) This isoflavone compound daidzein C ₁₅ H ₁₀ O _4, daidzin C ₂₁ H ₂₀ O _9, Puerto rarin C ₂₁ H ₂₀ O _9, rarin Puerto Xyloxide, luteolin, biocanin A, C ₁₆ H ₁₂ O ₅ and the like, and horses, coumarin. In addition, choline, acetylcholine-positive substances, cacaine, and puerarol cracked. It is used for fever as antipyretic medicine and sensitizing medicine in the treatment of motion. It is also used for hunger, fever, swelling, pain in the head and stuffy stomach, when the neck and shoulders are stretched out, and used to loosen the blood and heal the wound. It is also used for high blood pressure and explosive tinnitus.

The defector is the seed of Cassia obtusifolia L., Emodine, Obtufofolin, Obtucin C ₁₈ H ₁₆ O ₇ , Chrysoobtucin C ₁₉ H ₁₈ O ₇ , Aurantioobtucin C ₁₇ H ₁₄ O ₇ And its glycosides were separated. The water or alcohol extracts of the deficiency have a blood pressure-lowering effect in animal experiments. In motion therapy, it protects the kidneys, lowers the liver fever, and has the effect of wind and pain.

Bokbun is a fruit of Rubus sachalinensis Lev., Organic acid including 2.2% lemon acid, salinic acid, capronic acid, formic acid and salts thereof, large amount of pectin, carotene (0.3mg%), vitamin B group, glucose 4.3%, 8% fructose, 6.5% sucrose, 0.3% tannin, thianidine chloride C27H31O6, acetoin C4H8O2, β-nonone, benzaldehyde. Bokbunja decoction is a fever lowering effect and cardiac diuresis in animal experiments. In motion therapy, Bokbunja antipyretic fever is used as cold, febrile disease, pneumonia, cough, and gangjeong tonic.

The present invention is a food is not harmful to the human body at all, we are always edible food raw materials that are grown in the field of the edible food (edible), antler, kwak hyang, kaleun, cornus, white horse, sign, hawthorn, incense, throat It is useful because it is finely pulverized, dried, powdered, dried, powdered, powdered, powdered, and powdered, which is not harmful to the human body, and is involved in metabolic actions such as promoting blood circulation. In view of the effects that occur, the present invention is the effect of promoting blood circulation by mixing 12 different herbal medicines. However, this effect is not an effect generated from each of the components of the present invention, but is an effect caused by the organic components combined with each other.

That is, in the present invention, as a drug that cooks energy as a cooperative component of the blood circulation function and communicates energy to remove clogged areas to help blood circulation, neck and aroma are used, and the odor causes moisture to cause gas. Kwakhyang, construction workers and mountain lions are used to help the blood circulation by removing and protecting the digestive organs. If you take a lot or take it for a long time, it easily damages the essence (good substance) and consumes it regularly. Add goji berry, add antler and bokbunja to replenish regular consumption, add cornus oil to replenish regular consumption and damage of essence, and prevent damage to fluid and prevent loss of essence White horses and missing people are supplemented. The ingredients contained in the health food composition of the present invention are all herbal medicines, foods To be used as fuel and food intake when taking or excellent safety for the human body.

The formulation of the preferred food composition according to the present invention is powdered according to a conventional method, but is extracted with hot water or an organic solvent, dried with a carrier, then encapsulated, or formulated in the form of other tablets, granules, powders, beverages, porridge, and the like. Can be.

Examples of the health food composition for promoting blood circulation of the present invention are as follows.

Example 1 Composition for Promoting Blood Circulation (Unit: Weight% of Total 100)

Wolfberry 9% by weight

Deer Antler 9% by weight

Outline 9% by weight

Root weight 9

Cornus 8% by weight

8% by weight of white horse

Sine 8% by weight

Sun Lion 8% by weight

Aroma 8 wt%

8% by weight

8% by weight of defector

Bokbunja 8 wt%

Hereinafter, an animal experiment for measuring blood circulation promoting effect according to an embodiment of the present invention and clinical experiments applied to the human body and the results are presented.

Experimental Example 1: Blood circulation promoting effect experiment (animal experiment)

In order to measure the vasodilation effect of the blood food promoting health food composition of the present invention, the expansion effect on KCl-induced vasoconstriction was measured by using the lower limb arteries of rats.

As experimental animals, Sprague-Dawley rats with a body weight of about 20 to 25 g were allowed to acclimate for at least one week in an animal breeding room maintained at constant temperature and humidity. Selected and divided into two groups (10 씩 each), the normal control group was fed ginkgo biloba extract, the experimental group was dissolved in saline solution of the health food composition for promoting blood circulation of the present invention and fed once per day at 0.14mg per 250g body weight It was.

As shown in Table 1, it was confirmed that the present invention blood circulation promoting health food composition for KCl 72.7mM induced vasoconstriction has a superior vasodilation effect than ginkgo leaf extract.

Vasodilation effect on KCl of the health food composition for promoting blood circulation of the present invention Treatment concentration (M) % Shrinkage for 72.7 mM KCl Mean ± Standard Deviation 1 time Episode 2 3rd time 4 times Composition for promoting blood circulation 93.7 75.1 86.4 81.8 84.25 ± 6.78 Ginkgo leaf extract 47.3 60.2 52.8 66.1 56.60 ± 7.14

Experimental Example 2 Measurement of Inhibition of Arteriosclerosis

Ten male rats selected in Experimental Example 1 were used as the first group, and only olive oil was used in the normal group, and 40 m / kg cholesterol and 3200 IU / kg cholesterol were simultaneously dissolved in olive oil once a day for 28 days. Oral administration caused atherosclerosis. Here, the blood circulation promoting composition of the present invention was post-treated for 7 days at a concentration of 0.250 g / kg, respectively. The treatment method was orally administered once a day, and the same amount of normal saline was administered orally to the normal group and the control group.

On the last day of the experiment, the normal and control groups were fasted for 12 hours, and blood was collected from the abdominal aorta under urethane anesthesia. The obtained blood was centrifuged at 3000 rpm for 15 minutes to collect serum that was not hemolyzed, and then the total cholesterol content and HDL-cholesterol content in total cholesterol were measured by enzyme method, and triglyceride content and calcium content in serum were measured. Were each measured using a kit for measurement. The experimental results are shown in Table 2.

Arteriosclerosis inhibitory effect of the present invention for promoting blood circulation (mg / 100 mL) Total cholesterol HDL-Cholesterol / Total Cholesterol Triglycerides calcium Normal 72.1 ± 5.4 0.63 46.8 ± 8.01 15.9 ± 0.5 Arteriosclerosis group 73.8 ± 4.2 0.45 53.9 ± 4.2 20.7 ± 0.8 Blood circulation promoting composition administration group 73.1 ± 9.1 0.69 45.1 ± 3.5 18.6 ± 1.4

Experimental Example 3 Measurement of Analgesic Effect

The most commonly used method for screening analgesic substances is acetic acid induced writhing (Niemegeers, et al. Drug-Res. 1505 (1975). After 30 minutes of subcutaneous administration, 1.0% acetic acid was injected intraperitoneally with 0.1 mL / 10g per body weight to show writhing, which extends the hind foot, which is a method of measuring the number of writhings for 10 minutes from 10 minutes after drug administration.

In this experimental example, 10 rats selected from Experiments 1 and 2 were used in the control group and the administration group of the present invention for promoting blood circulation. Saline was administered to the control group, the composition for administration of the blood circulation promoting composition of the present invention, the composition was suspended in 0.9% saline and administered for 2 weeks at 20 mg / kg / day, and writhing was measured at the same time every 7 days. Experimental results As shown in Table 3, it was confirmed that the present invention blood circulation promoting health food composition exhibits analgesic action against the headache caused by blood circulation disorder.

Lighting Experiment Results Lighting count Blockage rate (%) One week meal Two weeks meal One week meal Two weeks meal Control 15.53 ± 8.71 18.24 ± 7.56 - - Blood circulation promoting composition administration group 11.25 ± 7.12 6.41 ± 4.76 36.2 67.5

According to the present invention as described in the above examples and experimental examples, the present invention provides a healthy food for promoting blood circulation, and when used, has an excellent effect of satisfying the user without side effects, and promotes blood circulation, arteriosclerosis, and blood circulation disorder. Because of the excellent effect in the treatment of headaches is a very useful invention in the health food industry.

Claims (1)

9% by weight of wolfberry, 9% by weight of deer antler, 9% by weight of kwak, 9% by weight of corn, 8% by weight of corn, 8% by weight of white horse, 8% by weight of hawthorn, 8% by weight of hawthorn, 8% by weight of wood, Health food composition for promoting blood circulation, characterized in that consisting of 8% by weight, bokbunja 8% by weight.