KE2988A - 4-substituted quinazoline cardiac stimulants - Google Patents

4-substituted quinazoline cardiac stimulants

Info

Publication number
KE2988A
KE2988A KE2988A KE298879A KE2988A KE 2988 A KE2988 A KE 2988A KE 2988 A KE2988 A KE 2988A KE 298879 A KE298879 A KE 298879A KE 2988 A KE2988 A KE 2988A
Authority
KE
Kenya
Prior art keywords
substituted quinazoline
cardiac stimulants
stimulants
cardiac
quinazoline
Prior art date
Application number
KE2988A
Other languages
English (en)
Inventor
C Thomson
A G Evans
J C Danilewicz
A L Ham
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of KE2988A publication Critical patent/KE2988A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KE2988A 1974-07-25 1979-09-05 4-substituted quinazoline cardiac stimulants KE2988A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3280574 1974-07-25
GB41675*[A GB1460389A (en) 1974-07-25 1975-01-06 4-substituted quinazoline cardiac stimulants

Publications (1)

Publication Number Publication Date
KE2988A true KE2988A (en) 1979-09-28

Family

ID=26235904

Family Applications (1)

Application Number Title Priority Date Filing Date
KE2988A KE2988A (en) 1974-07-25 1979-09-05 4-substituted quinazoline cardiac stimulants

Country Status (23)

Country Link
US (1) US4001422A (sk)
JP (1) JPS5527062B2 (sk)
AR (7) AR216046A1 (sk)
BG (2) BG27086A3 (sk)
CA (1) CA1060445A (sk)
CH (2) CH611616A5 (sk)
DD (1) DD119046A5 (sk)
DE (1) DE2530894C2 (sk)
DK (1) DK138800B (sk)
FI (1) FI66182C (sk)
FR (1) FR2279406A1 (sk)
GB (1) GB1460389A (sk)
HK (1) HK61879A (sk)
IE (1) IE41838B1 (sk)
IL (1) IL47625A (sk)
KE (1) KE2988A (sk)
LU (1) LU73072A1 (sk)
MY (1) MY8000108A (sk)
NL (1) NL159982C (sk)
PH (1) PH14190A (sk)
RO (3) RO69296A (sk)
SE (1) SE420921B (sk)
YU (3) YU37155B (sk)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN148482B (sk) 1977-06-03 1981-03-07 Pfizer
CA1086735A (en) * 1977-11-03 1980-09-30 John C. Danilewicz Piperidino-quinazolines
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
US4489075A (en) * 1982-05-15 1984-12-18 Pfizer Inc. Cyclic sulfonamidoalkyl substituted 4-piperidinoquinazoline cardiac stimulants
JPS61215389A (ja) * 1985-03-20 1986-09-25 Kyowa Hakko Kogyo Co Ltd キナゾリン誘導体およびそれを含有する強心剤
US6645969B1 (en) * 1991-05-10 2003-11-11 Aventis Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
FR2802206B1 (fr) * 1999-12-14 2005-04-22 Sod Conseils Rech Applic Derives de 4-aminopiperidine et leur utilisation en tant que medicament
TWI283665B (en) * 2001-09-13 2007-07-11 Smithkline Beecham Plc Novel urea compound, pharmaceutical composition containing the same and its use
HUP0200849A2 (hu) * 2002-03-06 2004-08-30 Sanofi-Synthelabo N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
US7064211B2 (en) * 2002-03-22 2006-06-20 Eisai Co., Ltd. Hemiasterlin derivatives and uses thereof
WO2004024710A1 (en) * 2002-09-13 2004-03-25 Glaxo Group Limited Urea compounds active as vanilloid receptor antagonists for the treatment of pain
TWI350168B (en) 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
NZ551603A (en) * 2004-06-24 2010-11-26 Incyte Corp N-substituted piperidines and their use as pharmaceuticals
US20060009471A1 (en) * 2004-06-24 2006-01-12 Wenqing Yao Amido compounds and their use as pharmaceuticals
JP2008504279A (ja) * 2004-06-24 2008-02-14 インサイト・コーポレイション アミド化合物およびその医薬としての使用
JP2008504280A (ja) * 2004-06-24 2008-02-14 インサイト・コーポレイション 2−メチルプロパンアミドおよびその医薬としての使用
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
MX2007001540A (es) * 2004-08-10 2007-04-23 Incyte Corp Compuestos amido y sus usos como farmaceuticos.
US8071768B2 (en) * 2005-06-10 2011-12-06 Janssen Pharmaceutica, N.V. Alkylquinoline and alkylquinazoline kinase modulators
US7825244B2 (en) * 2005-06-10 2010-11-02 Janssen Pharmaceutica Nv Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
TW200808807A (en) * 2006-03-02 2008-02-16 Incyte Corp Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
WO2007103719A2 (en) * 2006-03-03 2007-09-13 Incyte Corporation MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
CA2649677A1 (en) * 2006-05-01 2007-11-15 Incyte Corporation Tetrasubstituted ureas as modulators of 11-.beta. hydroxyl steroid dehydrogenase type 1
CA2652375A1 (en) * 2006-05-17 2007-11-29 Incyte Corporation Heterocyclic inhibitors of 11-.beta. hydroxyl steroid dehydrogenase type i and methods of using the same
EP1903038A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft N-(1-Hetaryl-piperidin-4-yl)-(het)arylamide als EP2-Rezeptor Modulatoren
EP1903037A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioharnstoffe als Modulatoren des EP2-Rezeptors
SG11202108288YA (en) * 2019-02-01 2021-08-30 Univ Leland Stanford Junior Enpp1 inhibitors and methods of modulating immune response
WO2020190912A1 (en) 2019-03-19 2020-09-24 Stingray Therapeutics, Inc. Quinoline and quinazoline compounds and methods of use thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1156973A (en) * 1965-07-06 1969-07-02 Quinazoline Derivatives
US3517005A (en) * 1967-10-26 1970-06-23 Pfizer & Co C Certain 2- and 4-substituted quinazolines
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3637701A (en) * 1969-03-03 1972-01-25 Sandoz Ag Certain nitrate derivatives of 4-aminoquinazolines
DE2121031A1 (en) * 1971-04-29 1972-11-02 Dr. Karl Thomae Gmbh, 7950 Biberach Base-substd quinazolines - thrombocyte aggregation inhibitors
BE793371A (fr) * 1971-12-27 1973-06-27 Sandoz Sa Nouveaux derives de la 4-amino-quinazoline, leur preparation etmedicaments contenant ces
US3819628A (en) * 1972-07-31 1974-06-25 Sandoz Ag 2-phenyl-4-substituted amino-quinazolines and nitrates thereof
US3838127A (en) * 1972-10-19 1974-09-24 Sandoz Ag 4-(4-(hydroxyalkyl)-1-piperazino)-quinazoline benzoates
GB1417029A (en) * 1973-03-07 1975-12-10 Pfizer Ltd Quinazoline-derived amines

Also Published As

Publication number Publication date
CH611616A5 (sk) 1979-06-15
RO69296A (ro) 1981-08-30
LU73072A1 (sk) 1977-03-24
YU124281A (en) 1983-04-30
NL159982C (nl) 1979-09-17
AR215882A1 (es) 1979-11-15
AR207895A1 (es) 1976-11-08
YU184275A (en) 1983-04-27
MY8000108A (en) 1980-12-31
DK337175A (sk) 1976-01-26
IE41838B1 (en) 1980-04-09
DD119046A5 (sk) 1976-04-05
GB1460389A (en) 1977-01-06
DE2530894A1 (de) 1976-02-05
PH14190A (en) 1981-03-26
NL159982B (nl) 1979-04-17
RO71840A (ro) 1982-09-09
CH608803A5 (sk) 1979-01-31
YU124181A (en) 1983-04-30
AR216046A1 (es) 1979-11-30
SE420921B (sv) 1981-11-09
BG27744A3 (en) 1979-12-12
CA1060445A (en) 1979-08-14
FR2279406B1 (sk) 1980-04-30
FI752104A (sk) 1976-01-26
JPS5527062B2 (sk) 1980-07-17
AU8317475A (en) 1977-01-20
FR2279406A1 (fr) 1976-02-20
YU37155B (en) 1984-08-31
NL7508824A (nl) 1976-01-27
JPS5136469A (sk) 1976-03-27
IL47625A0 (en) 1975-10-15
BG27086A3 (bg) 1979-08-15
DE2530894C2 (de) 1983-12-22
DK138800C (sk) 1979-04-09
IE41838L (en) 1976-01-25
SE7508101L (sv) 1976-01-26
HK61879A (en) 1979-09-07
AR213407A1 (es) 1979-01-31
AR214050A1 (es) 1979-04-30
RO71841A (ro) 1980-08-15
AR212447A1 (es) 1978-07-14
FI66182C (fi) 1984-09-10
FI66182B (fi) 1984-05-31
DK138800B (da) 1978-10-30
IL47625A (en) 1981-01-30
US4001422A (en) 1977-01-04
AR214049A1 (es) 1979-04-30

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