JPWO2023277168A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2023277168A5 JPWO2023277168A5 JP2023532082A JP2023532082A JPWO2023277168A5 JP WO2023277168 A5 JPWO2023277168 A5 JP WO2023277168A5 JP 2023532082 A JP2023532082 A JP 2023532082A JP 2023532082 A JP2023532082 A JP 2023532082A JP WO2023277168 A5 JPWO2023277168 A5 JP WO2023277168A5
- Authority
- JP
- Japan
- Prior art keywords
- polynucleotide
- nucleotides
- modified
- sugar
- nucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021109239 | 2021-06-30 | ||
| JP2021169846 | 2021-10-15 | ||
| PCT/JP2022/026411 WO2023277168A1 (ja) | 2021-06-30 | 2022-06-30 | ポリヌクレオチド及び医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023277168A1 JPWO2023277168A1 (https=) | 2023-01-05 |
| JPWO2023277168A5 true JPWO2023277168A5 (https=) | 2025-07-02 |
Family
ID=84692765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023532082A Pending JPWO2023277168A1 (https=) | 2021-06-30 | 2022-06-30 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240325426A1 (https=) |
| EP (1) | EP4365288A4 (https=) |
| JP (1) | JPWO2023277168A1 (https=) |
| KR (1) | KR20240026181A (https=) |
| AU (1) | AU2022302611A1 (https=) |
| CA (1) | CA3225964A1 (https=) |
| WO (1) | WO2023277168A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024185697A1 (ja) * | 2023-03-03 | 2024-09-12 | 国立大学法人東海国立大学機構 | ポリヌクレオチド連結産物の製造方法 |
| WO2025111430A1 (en) * | 2023-11-21 | 2025-05-30 | Prime Medicine, Inc. | CHEMICAL MODIFICATIONS IN mRNA POLY(A) TAIL |
| WO2026010855A1 (en) * | 2024-07-02 | 2026-01-08 | Trilink Biotechnologies, Llc | Modified rna for increasing protein expression |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01114346A (ja) | 1987-10-26 | 1989-05-08 | Seiko Electronic Components Ltd | 冷却ファン付モータ |
| US20030083272A1 (en) * | 1997-09-19 | 2003-05-01 | Lahive & Cockfield, Llp | Sense mrna therapy |
| CA2723265C (en) * | 2008-05-02 | 2015-11-24 | Epicentre Technologies Corporation | Selective 5' ligation tagging of rna |
| EP3460064B8 (en) * | 2011-04-03 | 2024-03-20 | The General Hospital Corporation d/b/a Massachusetts General Hospital | Efficient protein expression in vivo using modified rna (mod-rna) |
| JP5678022B2 (ja) | 2012-10-31 | 2015-02-25 | 京セラドキュメントソリューションズ株式会社 | 画像形成装置及び画像形成プログラム |
| AU2013374345A1 (en) * | 2013-01-17 | 2015-08-06 | Moderna Therapeutics, Inc. | Signal-sensor polynucleotides for the alteration of cellular phenotypes |
| CA2955375A1 (en) | 2014-07-17 | 2016-01-21 | Modernatx, Inc. | Terminal modifications of polynucleotides |
| JP6275576B2 (ja) | 2014-07-24 | 2018-02-07 | ヤンマー株式会社 | 作業車輌 |
| US20180085391A1 (en) | 2014-08-08 | 2018-03-29 | Modernatx, Inc. | Compositions and methods for the treatment of ophthalmic diseases and conditions |
| EP3233132A4 (en) * | 2014-12-19 | 2018-06-27 | Modernatx, Inc. | Terminal modifications of polynucleotides |
| KR102789862B1 (ko) | 2016-01-11 | 2025-04-03 | 인네이트 튜머 이뮤니티, 인코포레이티드 | Sting 활성과 연관된 상태 예컨대 암의 치료를 위한 시클릭 디뉴클레오티드 |
| EP4082579A4 (en) * | 2019-12-26 | 2024-06-26 | National University Corporation Tokai National Higher Education and Research System | POLYNUCLEOTIDE AND MEDICINAL COMPOSITION |
-
2022
- 2022-06-30 AU AU2022302611A patent/AU2022302611A1/en active Pending
- 2022-06-30 US US18/575,623 patent/US20240325426A1/en active Pending
- 2022-06-30 EP EP22833314.2A patent/EP4365288A4/en active Pending
- 2022-06-30 WO PCT/JP2022/026411 patent/WO2023277168A1/ja not_active Ceased
- 2022-06-30 KR KR1020247001879A patent/KR20240026181A/ko active Pending
- 2022-06-30 CA CA3225964A patent/CA3225964A1/en active Pending
- 2022-06-30 JP JP2023532082A patent/JPWO2023277168A1/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2023277168A5 (https=) | ||
| RU2017114156A (ru) | N-ацетилгалактозаминовые (galnac) фосфорамитиды, их конъюгаты с нуклеиновыми кислотами и их применение | |
| JP6284977B2 (ja) | 2’−o−修飾rna | |
| KR20240028502A (ko) | 핵산 리간드 및 이의 접합체, 및 이를 위한 제조 방법 및 이의 용도 | |
| JP2023113843A5 (https=) | ||
| JP2022519019A5 (https=) | ||
| JP2019522972A5 (https=) | ||
| JP2016523087A5 (https=) | ||
| JP2015518714A5 (https=) | ||
| JP2010538677A5 (https=) | ||
| WO2020238766A1 (zh) | 核酸、药物组合物与缀合物及制备方法和用途 | |
| JP2026016798A (ja) | オリゴヌクレオチド組成物及びその作製方法 | |
| JPWO2023106310A5 (https=) | ||
| JP2021505129A5 (https=) | ||
| WO2018177825A1 (en) | Orthogonal protecting groups for the preparation of stereodefined phosphorothioate oligonucleotides | |
| JP2019213567A (ja) | ヘアピン型一本鎖rna分子の製造方法 | |
| WO2020233680A1 (zh) | 核酸、药物组合物与缀合物及制备方法和用途 | |
| JPWO2021070494A5 (https=) | ||
| US20230220386A1 (en) | Sirna conjugate, double-stranded sirna conjugate, salt thereof and application thereof | |
| AU2023231320A1 (en) | Application of tetracyclic compound in treatment of tumors | |
| JPH09510206A (ja) | オリゴヌクレオチドの合成に用いる組成物および方法 | |
| JP2000512630A (ja) | 2’―置換ヌクレオシドおよびオリゴヌクレオチド誘導体 | |
| CA2179987C (en) | Monohydrate of (e)-2'-deoxy-2'-(fluoromethylene)cytidine | |
| US8680262B2 (en) | Purification of oligonucleotides | |
| ES3062040T3 (en) | Glycoside compound, amidite compound, and production method for polynucleotide using said compounds |