JPWO2023275366A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2023275366A5 JPWO2023275366A5 JP2023580488A JP2023580488A JPWO2023275366A5 JP WO2023275366 A5 JPWO2023275366 A5 JP WO2023275366A5 JP 2023580488 A JP2023580488 A JP 2023580488A JP 2023580488 A JP2023580488 A JP 2023580488A JP WO2023275366 A5 JPWO2023275366 A5 JP WO2023275366A5
- Authority
- JP
- Japan
- Prior art keywords
- diol
- hydroxy
- phenyl
- amino
- propane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163217970P | 2021-07-02 | 2021-07-02 | |
| US63/217,970 | 2021-07-02 | ||
| PCT/EP2022/068292 WO2023275366A1 (en) | 2021-07-02 | 2022-07-01 | Nlrp3 inflammasome inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024523623A JP2024523623A (ja) | 2024-06-28 |
| JPWO2023275366A5 true JPWO2023275366A5 (https=) | 2025-06-30 |
| JP2024523623A5 JP2024523623A5 (https=) | 2025-06-30 |
Family
ID=82611090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023580488A Pending JP2024523623A (ja) | 2021-07-02 | 2022-07-01 | Ｎｌｒｐ３インフラマソーム阻害剤 |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US11970463B2 (https=) |
| EP (2) | EP4628490A3 (https=) |
| JP (1) | JP2024523623A (https=) |
| KR (1) | KR20240031343A (https=) |
| CN (1) | CN117580826A (https=) |
| AR (1) | AR126351A1 (https=) |
| AU (2) | AU2022304254B2 (https=) |
| BR (1) | BR112023026976A2 (https=) |
| CA (1) | CA3224513A1 (https=) |
| CL (1) | CL2023003939A1 (https=) |
| CO (1) | CO2024000565A2 (https=) |
| CR (1) | CR20240038A (https=) |
| DK (1) | DK4363406T3 (https=) |
| DO (1) | DOP2024000002A (https=) |
| EC (1) | ECSP24008862A (https=) |
| ES (1) | ES3054790T3 (https=) |
| FI (1) | FI4363406T3 (https=) |
| HR (1) | HRP20251513T1 (https=) |
| IL (1) | IL309680A (https=) |
| LT (1) | LT4363406T (https=) |
| MA (1) | MA65277B1 (https=) |
| MX (1) | MX2024000234A (https=) |
| PE (1) | PE20250122A1 (https=) |
| PL (1) | PL4363406T3 (https=) |
| PT (1) | PT4363406T (https=) |
| RS (1) | RS67463B1 (https=) |
| SI (1) | SI4363406T1 (https=) |
| SM (1) | SMT202500441T1 (https=) |
| TW (1) | TW202321201A (https=) |
| UY (1) | UY39839A (https=) |
| WO (1) | WO2023275366A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11618751B1 (en) | 2022-03-25 | 2023-04-04 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
| US11319319B1 (en) | 2021-04-07 | 2022-05-03 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| KR20240019083A (ko) | 2021-06-04 | 2024-02-14 | 에프. 호프만-라 로슈 아게 | 트리아진 유도체 및 암 치료에서 이의 용도 |
| MX2024000984A (es) * | 2021-07-21 | 2024-06-19 | Nico Therapeutics Inc | Compuesto de piridazina anilado. |
| IL310992A (en) | 2021-08-25 | 2024-04-01 | Ptc Therapeutics Inc | NLRP3 inhibitors |
| US20240391881A1 (en) * | 2021-09-30 | 2024-11-28 | Origiant Pharmaceutical Co., Ltd. | Pharmaceutical use and preparation method for substituted heteroaryl phthalazine derivative |
| CN116102535A (zh) | 2021-10-22 | 2023-05-12 | 索智生物科技（浙江）有限公司 | 一种含氮化合物、其制备方法及应用 |
| US12331048B2 (en) | 2022-10-31 | 2025-06-17 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors |
| KR20250162767A (ko) * | 2022-12-28 | 2025-11-19 | 아스트라제네카 아베 | Nlrp3 인플라마좀 억제제의 결정질 형태, 화학 공정 및 화학적 화합물 |
| KR20250106322A (ko) | 2022-12-28 | 2025-07-09 | 장춘 진사이언스 파마슈티컬 씨오., 엘티디. | 피리다진계 nlrp3 억제제 화합물, 약학 조성물 및 이의 제조 방법과 용도 |
| AU2024280075A1 (en) | 2023-06-02 | 2025-12-11 | Merck Sharp & Dohme Llc | 5,6-Unsaturated Bicyclic Heterocycles Useful as Inhibitors of Nod-Like Receptor Protein 3 |
| WO2025111267A1 (en) * | 2023-11-20 | 2025-05-30 | Ventus Therapeutics U.S., Inc. | Solid freebase forms of 5-chloro-2-(4-((2-hydroxy-2- methylpropyl)amino)pyrido[3,4-d[pyridazin-1-yl)phenol for inhibiting nlrp3 and uses thereof |
| WO2025153532A1 (en) | 2024-01-16 | 2025-07-24 | NodThera Limited | Nlrp3 inhibitors and glp-1 agonists combination therapies |
| WO2026006510A1 (en) * | 2024-06-26 | 2026-01-02 | Virginia Commonwealth University | Compounds as nlrp3 inhibitors, and compositions and uses thereof |
| WO2026002229A1 (zh) * | 2024-06-28 | 2026-01-02 | 长春金赛药业有限责任公司 | 一种nlrp3抑制剂化合物及其制备方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1745039A4 (en) | 2004-05-08 | 2009-07-22 | Neurogen Corp | 3-ARYL-5,6-DISUBSTITUTED PYRIDAZINES |
| CN111315733A (zh) | 2017-11-09 | 2020-06-19 | 英夫拉索姆有限公司 | 新颖磺酰胺甲酰胺化合物 |
| UY38687A (es) * | 2019-05-17 | 2023-05-15 | Novartis Ag | Inhibidores del inflamasoma nlrp3, composiciones, combinaciones de los mismos y métodos para su uso |
| AR121669A1 (es) | 2020-03-27 | 2022-06-29 | Astellas Pharma Inc | Compuesto de piridazina sustituida |
| CN116390914A (zh) | 2020-12-25 | 2023-07-04 | 上海拓界生物医药科技有限公司 | 一类含哒嗪的化合物及其医药用途 |
| WO2022166890A1 (zh) | 2021-02-08 | 2022-08-11 | 南京明德新药研发有限公司 | 取代的哒嗪苯酚类衍生物 |
| US11319319B1 (en) | 2021-04-07 | 2022-05-03 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| US20240239758A1 (en) | 2021-04-28 | 2024-07-18 | Astellas Pharma Inc. | Substituted triazine compound |
| US20240327413A1 (en) | 2021-06-29 | 2024-10-03 | Zomagen Biosciences Ltd | Nlrp3 modulators |
-
2022
- 2022-07-01 HR HRP20251513TT patent/HRP20251513T1/hr unknown
- 2022-07-01 EP EP25190541.0A patent/EP4628490A3/en active Pending
- 2022-07-01 FI FIEP22744149.0T patent/FI4363406T3/fi active
- 2022-07-01 CR CR20240038A patent/CR20240038A/es unknown
- 2022-07-01 CA CA3224513A patent/CA3224513A1/en active Pending
- 2022-07-01 PE PE2023003486A patent/PE20250122A1/es unknown
- 2022-07-01 DK DK22744149.0T patent/DK4363406T3/da active
- 2022-07-01 MX MX2024000234A patent/MX2024000234A/es unknown
- 2022-07-01 LT LTEPPCT/EP2022/068292T patent/LT4363406T/lt unknown
- 2022-07-01 SI SI202230216T patent/SI4363406T1/sl unknown
- 2022-07-01 AR ARP220101723A patent/AR126351A1/es unknown
- 2022-07-01 ES ES22744149T patent/ES3054790T3/es active Active
- 2022-07-01 BR BR112023026976A patent/BR112023026976A2/pt unknown
- 2022-07-01 IL IL309680A patent/IL309680A/en unknown
- 2022-07-01 RS RS20251208A patent/RS67463B1/sr unknown
- 2022-07-01 AU AU2022304254A patent/AU2022304254B2/en active Active
- 2022-07-01 EP EP22744149.0A patent/EP4363406B1/en active Active
- 2022-07-01 US US17/810,367 patent/US11970463B2/en active Active
- 2022-07-01 WO PCT/EP2022/068292 patent/WO2023275366A1/en not_active Ceased
- 2022-07-01 JP JP2023580488A patent/JP2024523623A/ja active Pending
- 2022-07-01 PT PT227441490T patent/PT4363406T/pt unknown
- 2022-07-01 KR KR1020247003701A patent/KR20240031343A/ko active Pending
- 2022-07-01 CN CN202280045960.2A patent/CN117580826A/zh active Pending
- 2022-07-01 SM SM20250441T patent/SMT202500441T1/it unknown
- 2022-07-01 TW TW111124687A patent/TW202321201A/zh unknown
- 2022-07-01 PL PL22744149.0T patent/PL4363406T3/pl unknown
- 2022-07-01 MA MA65277A patent/MA65277B1/fr unknown
- 2022-07-04 UY UY0001039839A patent/UY39839A/es unknown
-
2023
- 2023-12-28 CL CL2023003939A patent/CL2023003939A1/es unknown
-
2024
- 2024-01-02 DO DO2024000002A patent/DOP2024000002A/es unknown
- 2024-01-24 CO CONC2024/0000565A patent/CO2024000565A2/es unknown
- 2024-02-02 EC ECSENADI20248862A patent/ECSP24008862A/es unknown
- 2024-03-21 US US18/612,849 patent/US12503445B2/en active Active
-
2025
- 2025-09-02 AU AU2025223957A patent/AU2025223957A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI4363406T3 (fi) | Nlrp3-inflammasomin estäjiä | |
| JPWO2023275366A5 (https=) | ||
| JP2014037426A5 (https=) | ||
| JP2011513367A5 (https=) | ||
| JP2017522348A5 (https=) | ||
| JP2010516702A5 (https=) | ||
| JP2013543896A5 (https=) | ||
| JP2017504640A5 (https=) | ||
| JP2007508360A5 (https=) | ||
| JP2021515773A5 (https=) | ||
| JP2009531292A5 (https=) | ||
| JP2005539054A5 (https=) | ||
| JP2012522759A5 (https=) | ||
| JP2013509431A5 (https=) | ||
| JP2020502047A5 (https=) | ||
| JP2021500403A5 (https=) | ||
| JP2019511527A (ja) | Ｐｐａｒアゴニスト、化合物、医薬組成物、及びその使用方法 | |
| JP2017522350A5 (https=) | ||
| JP2018507223A5 (https=) | ||
| JP2008537547A5 (https=) | ||
| RU2005106356A (ru) | Новое соединение | |
| RU2005106355A (ru) | Новое соединение | |
| JP2007518798A5 (https=) | ||
| JP2013544794A5 (https=) | ||
| JPWO2019226213A5 (https=) |