JP2024523623A5 - - Google Patents

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Publication number
JP2024523623A5
JP2024523623A5 JP2023580488A JP2023580488A JP2024523623A5 JP 2024523623 A5 JP2024523623 A5 JP 2024523623A5 JP 2023580488 A JP2023580488 A JP 2023580488A JP 2023580488 A JP2023580488 A JP 2023580488A JP 2024523623 A5 JP2024523623 A5 JP 2024523623A5
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JP
Japan
Application number
JP2023580488A
Other languages
Japanese (ja)
Other versions
JP2024523623A (ja
JPWO2023275366A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/068292 external-priority patent/WO2023275366A1/en
Publication of JP2024523623A publication Critical patent/JP2024523623A/ja
Publication of JPWO2023275366A5 publication Critical patent/JPWO2023275366A5/ja
Publication of JP2024523623A5 publication Critical patent/JP2024523623A5/ja
Pending legal-status Critical Current

Links

JP2023580488A 2021-07-02 2022-07-01 Nlrp3インフラマソーム阻害剤 Pending JP2024523623A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163217970P 2021-07-02 2021-07-02
US63/217,970 2021-07-02
PCT/EP2022/068292 WO2023275366A1 (en) 2021-07-02 2022-07-01 Nlrp3 inflammasome inhibitors

Publications (3)

Publication Number Publication Date
JP2024523623A JP2024523623A (ja) 2024-06-28
JPWO2023275366A5 JPWO2023275366A5 (https=) 2025-06-30
JP2024523623A5 true JP2024523623A5 (https=) 2025-06-30

Family

ID=82611090

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023580488A Pending JP2024523623A (ja) 2021-07-02 2022-07-01 Nlrp3インフラマソーム阻害剤

Country Status (31)

Country Link
US (2) US11970463B2 (https=)
EP (2) EP4628490A3 (https=)
JP (1) JP2024523623A (https=)
KR (1) KR20240031343A (https=)
CN (1) CN117580826A (https=)
AR (1) AR126351A1 (https=)
AU (2) AU2022304254B2 (https=)
BR (1) BR112023026976A2 (https=)
CA (1) CA3224513A1 (https=)
CL (1) CL2023003939A1 (https=)
CO (1) CO2024000565A2 (https=)
CR (1) CR20240038A (https=)
DK (1) DK4363406T3 (https=)
DO (1) DOP2024000002A (https=)
EC (1) ECSP24008862A (https=)
ES (1) ES3054790T3 (https=)
FI (1) FI4363406T3 (https=)
HR (1) HRP20251513T1 (https=)
IL (1) IL309680A (https=)
LT (1) LT4363406T (https=)
MA (1) MA65277B1 (https=)
MX (1) MX2024000234A (https=)
PE (1) PE20250122A1 (https=)
PL (1) PL4363406T3 (https=)
PT (1) PT4363406T (https=)
RS (1) RS67463B1 (https=)
SI (1) SI4363406T1 (https=)
SM (1) SMT202500441T1 (https=)
TW (1) TW202321201A (https=)
UY (1) UY39839A (https=)
WO (1) WO2023275366A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11618751B1 (en) 2022-03-25 2023-04-04 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives
US11319319B1 (en) 2021-04-07 2022-05-03 Ventus Therapeutics U.S., Inc. Compounds for inhibiting NLRP3 and uses thereof
KR20240019083A (ko) 2021-06-04 2024-02-14 에프. 호프만-라 로슈 아게 트리아진 유도체 및 암 치료에서 이의 용도
MX2024000984A (es) * 2021-07-21 2024-06-19 Nico Therapeutics Inc Compuesto de piridazina anilado.
IL310992A (en) 2021-08-25 2024-04-01 Ptc Therapeutics Inc NLRP3 inhibitors
US20240391881A1 (en) * 2021-09-30 2024-11-28 Origiant Pharmaceutical Co., Ltd. Pharmaceutical use and preparation method for substituted heteroaryl phthalazine derivative
CN116102535A (zh) 2021-10-22 2023-05-12 索智生物科技(浙江)有限公司 一种含氮化合物、其制备方法及应用
US12331048B2 (en) 2022-10-31 2025-06-17 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors
KR20250162767A (ko) * 2022-12-28 2025-11-19 아스트라제네카 아베 Nlrp3 인플라마좀 억제제의 결정질 형태, 화학 공정 및 화학적 화합물
KR20250106322A (ko) 2022-12-28 2025-07-09 장춘 진사이언스 파마슈티컬 씨오., 엘티디. 피리다진계 nlrp3 억제제 화합물, 약학 조성물 및 이의 제조 방법과 용도
AU2024280075A1 (en) 2023-06-02 2025-12-11 Merck Sharp & Dohme Llc 5,6-Unsaturated Bicyclic Heterocycles Useful as Inhibitors of Nod-Like Receptor Protein 3
WO2025111267A1 (en) * 2023-11-20 2025-05-30 Ventus Therapeutics U.S., Inc. Solid freebase forms of 5-chloro-2-(4-((2-hydroxy-2- methylpropyl)amino)pyrido[3,4-d[pyridazin-1-yl)phenol for inhibiting nlrp3 and uses thereof
WO2025153532A1 (en) 2024-01-16 2025-07-24 NodThera Limited Nlrp3 inhibitors and glp-1 agonists combination therapies
WO2026006510A1 (en) * 2024-06-26 2026-01-02 Virginia Commonwealth University Compounds as nlrp3 inhibitors, and compositions and uses thereof
WO2026002229A1 (zh) * 2024-06-28 2026-01-02 长春金赛药业有限责任公司 一种nlrp3抑制剂化合物及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1745039A4 (en) 2004-05-08 2009-07-22 Neurogen Corp 3-ARYL-5,6-DISUBSTITUTED PYRIDAZINES
CN111315733A (zh) 2017-11-09 2020-06-19 英夫拉索姆有限公司 新颖磺酰胺甲酰胺化合物
UY38687A (es) * 2019-05-17 2023-05-15 Novartis Ag Inhibidores del inflamasoma nlrp3, composiciones, combinaciones de los mismos y métodos para su uso
AR121669A1 (es) 2020-03-27 2022-06-29 Astellas Pharma Inc Compuesto de piridazina sustituida
CN116390914A (zh) 2020-12-25 2023-07-04 上海拓界生物医药科技有限公司 一类含哒嗪的化合物及其医药用途
WO2022166890A1 (zh) 2021-02-08 2022-08-11 南京明德新药研发有限公司 取代的哒嗪苯酚类衍生物
US11319319B1 (en) 2021-04-07 2022-05-03 Ventus Therapeutics U.S., Inc. Compounds for inhibiting NLRP3 and uses thereof
US20240239758A1 (en) 2021-04-28 2024-07-18 Astellas Pharma Inc. Substituted triazine compound
US20240327413A1 (en) 2021-06-29 2024-10-03 Zomagen Biosciences Ltd Nlrp3 modulators

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