JPWO2023182274A1 - - Google Patents

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Publication number
JPWO2023182274A1
JPWO2023182274A1 JP2024510168A JP2024510168A JPWO2023182274A1 JP WO2023182274 A1 JPWO2023182274 A1 JP WO2023182274A1 JP 2024510168 A JP2024510168 A JP 2024510168A JP 2024510168 A JP2024510168 A JP 2024510168A JP WO2023182274 A1 JPWO2023182274 A1 JP WO2023182274A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024510168A
Other languages
Japanese (ja)
Other versions
JPWO2023182274A5 (https=
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2023182274A1 publication Critical patent/JPWO2023182274A1/ja
Publication of JPWO2023182274A5 publication Critical patent/JPWO2023182274A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2024510168A 2022-03-23 2023-03-20 Pending JPWO2023182274A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2022047341 2022-03-23
PCT/JP2023/010891 WO2023182274A1 (ja) 2022-03-23 2023-03-20 核酸オリゴマーの製造方法

Publications (2)

Publication Number Publication Date
JPWO2023182274A1 true JPWO2023182274A1 (https=) 2023-09-28
JPWO2023182274A5 JPWO2023182274A5 (https=) 2024-12-03

Family

ID=88100953

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024510168A Pending JPWO2023182274A1 (https=) 2022-03-23 2023-03-20

Country Status (6)

Country Link
US (1) US12509485B2 (https=)
EP (1) EP4488282A4 (https=)
JP (1) JPWO2023182274A1 (https=)
KR (1) KR20240162536A (https=)
CN (1) CN118891269A (https=)
WO (1) WO2023182274A1 (https=)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007099896A1 (ja) * 2006-02-27 2007-09-07 Nippon Shinyaku Co., Ltd. 核酸保護基の脱離方法
WO2013027843A1 (ja) * 2011-08-25 2013-02-28 株式会社ボナック 配糖体化合物、チオエーテルの製造方法、エーテル、エーテルの製造方法、配糖体化合物の製造方法、核酸の製造方法
WO2021210409A1 (ja) * 2020-04-14 2021-10-21 住友化学株式会社 核酸オリゴマーを含む組成物
WO2022009959A1 (ja) * 2020-07-09 2022-01-13 住友化学株式会社 核酸オリゴマーの製造方法
WO2022064908A1 (ja) * 2020-09-24 2022-03-31 住友化学株式会社 核酸オリゴマーの製造方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6077709A (en) 1998-09-29 2000-06-20 Isis Pharmaceuticals Inc. Antisense modulation of Survivin expression
DK1149109T3 (da) 1999-02-05 2010-01-11 Ge Healthcare Bio Sciences Fremgangsmåde til afbeskyttelse af oligonukleotider
US6261840B1 (en) 2000-01-18 2001-07-17 Isis Pharmaceuticals, Inc. Antisense modulation of PTP1B expression
ES2386709T3 (es) 2004-08-26 2012-08-27 Nippon Shinyaku Co., Ltd. Compuesto de fosforamidita y método para producir un oligo-ARN
WO2008049085A1 (en) 2006-10-18 2008-04-24 Isis Pharmaceuticals, Inc. Antisense compounds
HUE037500T2 (hu) 2010-07-08 2018-08-28 Bonac Corp Egyszálú nukleinsav molekula a génexpresszió szabályozására
ES2527660T3 (es) 2010-08-03 2015-01-28 Bonac Corporation Molécula de ARN monocatenario que tiene esqueleto alicíclico que contiene nitrógeno
US9528111B2 (en) 2012-01-07 2016-12-27 Bonac Corporation Single-stranded nucleic acid molecule having amino acid backbone
EP3241902B1 (en) 2012-05-25 2018-02-28 The Regents of The University of California Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
US10900034B2 (en) 2014-12-03 2021-01-26 Agilent Technologies, Inc. Guide RNA with chemical modifications
JP6787398B2 (ja) 2016-04-26 2020-11-18 住友化学株式会社 一本鎖核酸分子用モノマーの製造方法
EP3604528A4 (en) 2017-03-31 2021-01-13 Bonac Corporation CYCLIC NUCLEIC ACID MOLECULE WITH GENE EXPRESSION CONTROL FUNCTION
KR20250046363A (ko) 2017-09-19 2025-04-02 알닐람 파마슈티칼스 인코포레이티드 트랜스타이레틴(ttr) 매개 아밀로이드증을 치료하기 위한 조성물 및 방법
US20210188895A1 (en) 2017-10-13 2021-06-24 Bonac Corporation Single-stranded nucleic acid molecule, and production method therefor
TWI830718B (zh) * 2018-02-09 2024-02-01 日商住友化學股份有限公司 核酸分子之製造方法
JP7570858B2 (ja) 2020-09-11 2024-10-22 日鉄ステンレス株式会社 マルテンサイト系ステンレス鋼板およびマルテンサイト系ステンレス鋼板の製造方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007099896A1 (ja) * 2006-02-27 2007-09-07 Nippon Shinyaku Co., Ltd. 核酸保護基の脱離方法
WO2013027843A1 (ja) * 2011-08-25 2013-02-28 株式会社ボナック 配糖体化合物、チオエーテルの製造方法、エーテル、エーテルの製造方法、配糖体化合物の製造方法、核酸の製造方法
WO2021210409A1 (ja) * 2020-04-14 2021-10-21 住友化学株式会社 核酸オリゴマーを含む組成物
WO2022009959A1 (ja) * 2020-07-09 2022-01-13 住友化学株式会社 核酸オリゴマーの製造方法
WO2022064908A1 (ja) * 2020-09-24 2022-03-31 住友化学株式会社 核酸オリゴマーの製造方法

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BIOORG. MED. CHEM., vol. 16, JPN6025019057, 2008, pages 9154 - 9160, ISSN: 0005592988 *
J. ORG. CHEM., vol. 77, JPN6025019056, 2012, pages 7913 - 7922, ISSN: 0005592987 *
NUCLEIC ACIDS SYMPOSIUM SERIES, vol. 48, JPN6023023567, 2004, pages 9 - 10, ISSN: 0005592990 *
TETRAHEDRON LETT., vol. 45, JPN6023023568, 2004, pages 9529 - 9531, ISSN: 0005592989 *
TETRAHEDRON LETT., vol. 87, JPN6025019055, 2021, pages 1 - 6, ISSN: 0005592986 *

Also Published As

Publication number Publication date
WO2023182274A1 (ja) 2023-09-28
US20250145655A1 (en) 2025-05-08
KR20240162536A (ko) 2024-11-15
CN118891269A (zh) 2024-11-01
EP4488282A4 (en) 2025-11-19
US12509485B2 (en) 2025-12-30
EP4488282A1 (en) 2025-01-08

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