JPWO2023182274A1 - - Google Patents
Info
- Publication number
- JPWO2023182274A1 JPWO2023182274A1 JP2024510168A JP2024510168A JPWO2023182274A1 JP WO2023182274 A1 JPWO2023182274 A1 JP WO2023182274A1 JP 2024510168 A JP2024510168 A JP 2024510168A JP 2024510168 A JP2024510168 A JP 2024510168A JP WO2023182274 A1 JPWO2023182274 A1 JP WO2023182274A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022047341 | 2022-03-23 | ||
| PCT/JP2023/010891 WO2023182274A1 (ja) | 2022-03-23 | 2023-03-20 | 核酸オリゴマーの製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023182274A1 true JPWO2023182274A1 (https=) | 2023-09-28 |
| JPWO2023182274A5 JPWO2023182274A5 (https=) | 2024-12-03 |
Family
ID=88100953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024510168A Pending JPWO2023182274A1 (https=) | 2022-03-23 | 2023-03-20 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12509485B2 (https=) |
| EP (1) | EP4488282A4 (https=) |
| JP (1) | JPWO2023182274A1 (https=) |
| KR (1) | KR20240162536A (https=) |
| CN (1) | CN118891269A (https=) |
| WO (1) | WO2023182274A1 (https=) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007099896A1 (ja) * | 2006-02-27 | 2007-09-07 | Nippon Shinyaku Co., Ltd. | 核酸保護基の脱離方法 |
| WO2013027843A1 (ja) * | 2011-08-25 | 2013-02-28 | 株式会社ボナック | 配糖体化合物、チオエーテルの製造方法、エーテル、エーテルの製造方法、配糖体化合物の製造方法、核酸の製造方法 |
| WO2021210409A1 (ja) * | 2020-04-14 | 2021-10-21 | 住友化学株式会社 | 核酸オリゴマーを含む組成物 |
| WO2022009959A1 (ja) * | 2020-07-09 | 2022-01-13 | 住友化学株式会社 | 核酸オリゴマーの製造方法 |
| WO2022064908A1 (ja) * | 2020-09-24 | 2022-03-31 | 住友化学株式会社 | 核酸オリゴマーの製造方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6077709A (en) | 1998-09-29 | 2000-06-20 | Isis Pharmaceuticals Inc. | Antisense modulation of Survivin expression |
| US6887990B1 (en) | 1999-02-05 | 2005-05-03 | Amersham Biosciences Corp | Method for deprotecting oligonucleotides |
| US6261840B1 (en) | 2000-01-18 | 2001-07-17 | Isis Pharmaceuticals, Inc. | Antisense modulation of PTP1B expression |
| AU2005275801B2 (en) | 2004-08-26 | 2012-05-10 | Nippon Shinyaku Co., Ltd. | Phosphoramidite compound and method for producing oligo-RNA |
| ES2526295T5 (es) | 2006-10-18 | 2021-05-04 | Ionis Pharmaceuticals Inc | Compuestos antisentido |
| EP2933333B1 (en) | 2010-07-08 | 2018-02-21 | Bonac Corporation | Single-strand nucleic acid molecule for controlling gene expression |
| EP2639307B1 (en) | 2010-08-03 | 2015-03-04 | Bonac Corporation | Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton |
| CN104039961A (zh) | 2012-01-07 | 2014-09-10 | 株式会社博纳克 | 具有氨基酸骨架的单链核酸分子 |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| CA2969619A1 (en) | 2014-12-03 | 2016-06-09 | Agilent Technologies, Inc. | Guide rna with chemical modifications |
| EP3450439B8 (en) | 2016-04-26 | 2021-06-30 | Sumitomo Chemical Company, Limited | Method for producing monomer for single-stranded nucleic acid molecule |
| JPWO2018182008A1 (ja) | 2017-03-31 | 2020-02-06 | 株式会社ボナック | 遺伝子発現制御機能を有する環状型核酸分子 |
| BR112020005230A2 (pt) | 2017-09-19 | 2020-09-24 | Alnylam Pharmaceuticals, Inc. | composições e métodos para o tratamento da amiloidose mediada por transtiretina (ttr) |
| US20210188895A1 (en) | 2017-10-13 | 2021-06-24 | Bonac Corporation | Single-stranded nucleic acid molecule, and production method therefor |
| TWI830718B (zh) * | 2018-02-09 | 2024-02-01 | 日商住友化學股份有限公司 | 核酸分子之製造方法 |
| JP7570858B2 (ja) | 2020-09-11 | 2024-10-22 | 日鉄ステンレス株式会社 | マルテンサイト系ステンレス鋼板およびマルテンサイト系ステンレス鋼板の製造方法 |
-
2023
- 2023-03-20 US US18/848,797 patent/US12509485B2/en active Active
- 2023-03-20 EP EP23774869.4A patent/EP4488282A4/en active Pending
- 2023-03-20 CN CN202380028404.9A patent/CN118891269A/zh active Pending
- 2023-03-20 WO PCT/JP2023/010891 patent/WO2023182274A1/ja not_active Ceased
- 2023-03-20 KR KR1020247034021A patent/KR20240162536A/ko active Pending
- 2023-03-20 JP JP2024510168A patent/JPWO2023182274A1/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007099896A1 (ja) * | 2006-02-27 | 2007-09-07 | Nippon Shinyaku Co., Ltd. | 核酸保護基の脱離方法 |
| WO2013027843A1 (ja) * | 2011-08-25 | 2013-02-28 | 株式会社ボナック | 配糖体化合物、チオエーテルの製造方法、エーテル、エーテルの製造方法、配糖体化合物の製造方法、核酸の製造方法 |
| WO2021210409A1 (ja) * | 2020-04-14 | 2021-10-21 | 住友化学株式会社 | 核酸オリゴマーを含む組成物 |
| WO2022009959A1 (ja) * | 2020-07-09 | 2022-01-13 | 住友化学株式会社 | 核酸オリゴマーの製造方法 |
| WO2022064908A1 (ja) * | 2020-09-24 | 2022-03-31 | 住友化学株式会社 | 核酸オリゴマーの製造方法 |
Non-Patent Citations (5)
| Title |
|---|
| BIOORG. MED. CHEM., vol. 16, JPN6025019057, 2008, pages 9154 - 9160, ISSN: 0005592988 * |
| J. ORG. CHEM., vol. 77, JPN6025019056, 2012, pages 7913 - 7922, ISSN: 0005592987 * |
| NUCLEIC ACIDS SYMPOSIUM SERIES, vol. 48, JPN6023023567, 2004, pages 9 - 10, ISSN: 0005592990 * |
| TETRAHEDRON LETT., vol. 45, JPN6023023568, 2004, pages 9529 - 9531, ISSN: 0005592989 * |
| TETRAHEDRON LETT., vol. 87, JPN6025019055, 2021, pages 1 - 6, ISSN: 0005592986 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20250145655A1 (en) | 2025-05-08 |
| WO2023182274A1 (ja) | 2023-09-28 |
| EP4488282A1 (en) | 2025-01-08 |
| CN118891269A (zh) | 2024-11-01 |
| US12509485B2 (en) | 2025-12-30 |
| EP4488282A4 (en) | 2025-11-19 |
| KR20240162536A (ko) | 2024-11-15 |
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