JPWO2023172879A5 - - Google Patents
Info
- Publication number
- JPWO2023172879A5 JPWO2023172879A5 JP2024553353A JP2024553353A JPWO2023172879A5 JP WO2023172879 A5 JPWO2023172879 A5 JP WO2023172879A5 JP 2024553353 A JP2024553353 A JP 2024553353A JP 2024553353 A JP2024553353 A JP 2024553353A JP WO2023172879 A5 JPWO2023172879 A5 JP WO2023172879A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- sequence
- acid sequence
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263268967P | 2022-03-07 | 2022-03-07 | |
| US63/268,967 | 2022-03-07 | ||
| PCT/US2023/063795 WO2023172879A2 (en) | 2022-03-07 | 2023-03-06 | Multiplex gene edited cells for cd70-directed cancer immunotherapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025508050A JP2025508050A (ja) | 2025-03-21 |
| JP2025508050A5 JP2025508050A5 (https=) | 2026-03-12 |
| JPWO2023172879A5 true JPWO2023172879A5 (https=) | 2026-03-12 |
Family
ID=87935884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024553353A Pending JP2025508050A (ja) | 2022-03-07 | 2023-03-06 | Ｃｄ７０指向性がん免疫療法のための多重遺伝子編集細胞 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230390392A1 (https=) |
| EP (1) | EP4482872A4 (https=) |
| JP (1) | JP2025508050A (https=) |
| AU (1) | AU2023232083A1 (https=) |
| CA (1) | CA3254363A1 (https=) |
| WO (1) | WO2023172879A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015259877B2 (en) | 2014-05-15 | 2021-02-25 | National University Of Singapore | Modified natural killer cells and uses thereof |
| KR102660336B1 (ko) | 2017-03-27 | 2024-04-26 | 내셔널 유니버시티 오브 싱가포르 | 절단된 nkg2d 키메라 수용체 및 자연 살해 세포 면역요법에서의 그의 용도 |
| AU2019219454A1 (en) | 2018-02-09 | 2020-08-27 | National University Of Singapore | Activating chimeric receptors and uses thereof in natural killer cell immunotherapy |
| CN112055717B (zh) | 2018-04-02 | 2024-04-26 | 新加坡国立大学 | 用在免疫细胞中表达的膜结合抗细胞因子非信号传导粘合剂中和人细胞因子 |
| EP3844186A4 (en) | 2018-08-29 | 2022-08-17 | National University of Singapore | METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS |
| AU2020232691B2 (en) | 2019-03-05 | 2023-06-29 | Nkarta, Inc. | CD19-directed chimeric antigen receptors and uses thereof in immunotherapy |
| WO2021252804A1 (en) | 2020-06-12 | 2021-12-16 | Nkarta, Inc. | Genetically modified natural killer cells for cd70-directed cancer immunotherapy |
| CN117844811A (zh) * | 2024-03-08 | 2024-04-09 | 上海恒润达生生物科技股份有限公司 | 靶向敲除CD70基因的sgRNA组合物及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030022311A1 (en) * | 1996-05-21 | 2003-01-30 | Dunnington Damien D. | Human CIS protein |
| US20050271660A1 (en) * | 2002-09-06 | 2005-12-08 | Alexion Pharmaceuticals, Inc. | Nebulization of monoclonal antibodies for treating pulmonary diseases |
| CN101203241B (zh) * | 2005-04-19 | 2012-02-22 | 西雅图基因公司 | 人源化抗-cd70结合物和其应用 |
| ES3063961T3 (en) * | 2014-02-14 | 2026-04-21 | Cellectis | Cells for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells |
| US11166985B2 (en) * | 2017-05-12 | 2021-11-09 | Crispr Therapeutics Ag | Materials and methods for engineering cells and uses thereof in immuno-oncology |
| JP2021502077A (ja) * | 2017-11-06 | 2021-01-28 | エディタス・メディシン，インコーポレイテッド | 免疫療法のためのｔ細胞におけるｃｂｌｂのｃｒｉｓｐｒ−ｃａｓ９編集のための方法、組成物および構成要素 |
| US20210396739A1 (en) * | 2018-05-01 | 2021-12-23 | Novartis Ag | Biomarkers for evaluating car-t cells to predict clinical outcome |
| US12227763B2 (en) * | 2018-05-11 | 2025-02-18 | Crispr Therapeutics Ag | Methods and compositions for treating cancer |
| BR112022009204A2 (pt) * | 2019-11-13 | 2022-07-26 | Crispr Therapeutics Ag | Terapia de carcinoma de células renais (rcc) usando células t geneticamente manipuladas visando cd70 |
| KR20220119038A (ko) * | 2019-11-25 | 2022-08-26 | 케이에스큐 세러퓨틱스 인코포레이티드 | 종양 침윤 림프구의 활성화 및 확장을 위한 방법 |
| CN115297890A (zh) * | 2020-02-03 | 2022-11-04 | 国立大学法人东海国立大学机构 | 用于对患癌的对象处置癌的抗meflin抗体和含有该抗体的药物组合物 |
| WO2021252804A1 (en) * | 2020-06-12 | 2021-12-16 | Nkarta, Inc. | Genetically modified natural killer cells for cd70-directed cancer immunotherapy |
| JP2023536818A (ja) * | 2020-07-29 | 2023-08-30 | ヤンセン バイオテツク，インコーポレーテツド | Ｈｌａ－ｇ抗原結合ドメインを含むタンパク質及びそれらの使用 |
-
2023
- 2023-03-06 CA CA3254363A patent/CA3254363A1/en active Pending
- 2023-03-06 AU AU2023232083A patent/AU2023232083A1/en active Pending
- 2023-03-06 JP JP2024553353A patent/JP2025508050A/ja active Pending
- 2023-03-06 EP EP23767591.3A patent/EP4482872A4/en active Pending
- 2023-03-06 WO PCT/US2023/063795 patent/WO2023172879A2/en not_active Ceased
- 2023-03-06 US US18/179,201 patent/US20230390392A1/en active Pending
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