JPWO2023068226A5 - - Google Patents

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Publication number
JPWO2023068226A5
JPWO2023068226A5 JP2023554675A JP2023554675A JPWO2023068226A5 JP WO2023068226 A5 JPWO2023068226 A5 JP WO2023068226A5 JP 2023554675 A JP2023554675 A JP 2023554675A JP 2023554675 A JP2023554675 A JP 2023554675A JP WO2023068226 A5 JPWO2023068226 A5 JP WO2023068226A5
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JP
Japan
Prior art keywords
antibody
amino acid
acid sequence
heavy chain
light chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023554675A
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English (en)
Japanese (ja)
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JPWO2023068226A1 (https=
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Publication date
Application filed filed Critical
Priority claimed from PCT/JP2022/038604 external-priority patent/WO2023068226A1/ja
Publication of JPWO2023068226A1 publication Critical patent/JPWO2023068226A1/ja
Publication of JPWO2023068226A5 publication Critical patent/JPWO2023068226A5/ja
Pending legal-status Critical Current

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JP2023554675A 2021-10-18 2022-10-17 Pending JPWO2023068226A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021170114 2021-10-18
PCT/JP2022/038604 WO2023068226A1 (ja) 2021-10-18 2022-10-17 抗cd37抗体-薬物コンジュゲート

Publications (2)

Publication Number Publication Date
JPWO2023068226A1 JPWO2023068226A1 (https=) 2023-04-27
JPWO2023068226A5 true JPWO2023068226A5 (https=) 2024-06-28

Family

ID=86059233

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023554675A Pending JPWO2023068226A1 (https=) 2021-10-18 2022-10-17

Country Status (12)

Country Link
US (2) US12138315B2 (https=)
EP (1) EP4420683A1 (https=)
JP (1) JPWO2023068226A1 (https=)
KR (1) KR20240099178A9 (https=)
CN (1) CN118119408A (https=)
AU (1) AU2022368385A1 (https=)
CA (1) CA3235358A1 (https=)
CO (1) CO2024003299A2 (https=)
IL (1) IL312237A (https=)
MX (1) MX2024004048A (https=)
TW (1) TW202330041A (https=)
WO (1) WO2023068226A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4699622A1 (en) * 2023-04-19 2026-02-25 Daiichi Sankyo Company, Limited Combination of antibody-drug conjugate and other medicine
EP4737483A1 (en) 2023-06-30 2026-05-06 Daiichi Sankyo Company, Limited Antibody-drug conjugate production method including purification step using activated carbon material
AU2024362226A1 (en) 2023-10-18 2026-03-05 Debiopharm International S.A. Drug combination comprising anti-cd37 antibody maytansine conjugate and bcl2 inhibitor or pi3k inhibitor
CN117264072B (zh) * 2023-11-22 2024-03-22 江苏迈威康新药研发有限公司 一种抗sn38单抗及其应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
DK0585287T3 (da) 1990-07-10 2000-04-17 Cambridge Antibody Tech Fremgangsmåde til fremstilling af specifikke bindingsparelementer
EP0605522B1 (en) 1991-09-23 1999-06-23 Medical Research Council Methods for the production of humanized antibodies
PT1024191E (pt) 1991-12-02 2008-12-22 Medical Res Council Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
CA2131151A1 (en) 1992-03-24 1994-09-30 Kevin S. Johnson Methods for producing members of specific binding pairs
GB9313509D0 (en) 1993-06-30 1993-08-11 Medical Res Council Chemisynthetic libraries
WO1995015388A1 (en) 1993-12-03 1995-06-08 Medical Research Council Recombinant binding proteins and peptides
DK1071700T3 (da) 1998-04-20 2010-06-07 Glycart Biotechnology Ag Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet
CA2704600C (en) 1999-04-09 2016-10-25 Kyowa Kirin Co., Ltd. A method for producing antibodies with increased adcc activity
CA2953239A1 (en) 2000-10-06 2002-04-18 Kyowa Hakko Kirin Co., Ltd. Antibody composition-producing cell
RU2423381C2 (ru) * 2005-07-25 2011-07-10 Трабьон Фармасьютикалз, Инк. Снижение количества в-клеток с использованием cd37-специфических и cd20-специфических связывающих молекул
WO2007133855A2 (en) 2006-03-27 2007-11-22 University Of Maryland Biotechnology Institute Glycoprotein synthesis and remodeling by enzymatic transglycosylation
PE20140196A1 (es) 2007-08-09 2014-03-19 Boehringer Ingelheim Int Anticuerpos anti-cd37
SG10201501803YA (en) 2010-03-12 2015-05-28 Immunogen Inc Cd37-binding molecules and immunoconjugates thereof
AU2012236210B2 (en) 2011-04-01 2016-02-04 Immunogen, Inc. CD37-binding molecules and immunoconjugates thereof
CA2858964A1 (en) 2011-12-13 2013-06-20 Nordic Nanovector As Chimeric therapeutic anti-cd37 antibodie hh1
IN2014DN06806A (https=) 2012-02-10 2015-05-22 Univ Maryland
ES2773710T3 (es) 2012-10-11 2020-07-14 Daiichi Sankyo Co Ltd Enlazadores para conjugados de anticuerpo - fármaco
WO2015017552A1 (en) * 2013-08-01 2015-02-05 Agensys, Inc. Antibody drug conjugates (adc) that bind to cd37 proteins
AU2014371934B2 (en) 2013-12-25 2020-01-23 Daiichi Sankyo Company, Limited Anti-TROP2 antibody-drug conjugate
CN116059395A (zh) * 2015-06-29 2023-05-05 第一三共株式会社 用于选择性制造抗体-药物缀合物的方法
SG11202100653YA (en) * 2018-07-25 2021-02-25 Daiichi Sankyo Co Ltd Effective method for manufacturing antibody-drug conjugate

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