JPWO2023046698A5 - - Google Patents
Info
- Publication number
- JPWO2023046698A5 JPWO2023046698A5 JP2024517459A JP2024517459A JPWO2023046698A5 JP WO2023046698 A5 JPWO2023046698 A5 JP WO2023046698A5 JP 2024517459 A JP2024517459 A JP 2024517459A JP 2024517459 A JP2024517459 A JP 2024517459A JP WO2023046698 A5 JPWO2023046698 A5 JP WO2023046698A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- fluorophenyl
- chloro
- pyridazin
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21198025.5 | 2021-09-21 | ||
| EP21198025 | 2021-09-21 | ||
| EP21216519 | 2021-12-21 | ||
| EP21216519.5 | 2021-12-21 | ||
| PK598/2022 | 2022-09-13 | ||
| PK5982022 | 2022-09-13 | ||
| PCT/EP2022/076130 WO2023046698A1 (en) | 2021-09-21 | 2022-09-20 | Pyridazinyl amino derivatives as alk5 inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024534510A JP2024534510A (ja) | 2024-09-20 |
| JP2024534510A5 JP2024534510A5 (https=) | 2025-09-30 |
| JPWO2023046698A5 true JPWO2023046698A5 (https=) | 2025-09-30 |
Family
ID=83978901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024517459A Withdrawn JP2024534510A (ja) | 2021-09-21 | 2022-09-20 | Ａｌｋ５阻害剤としてのピリダジニルアミノ誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250011299A1 (https=) |
| EP (1) | EP4405343A1 (https=) |
| JP (1) | JP2024534510A (https=) |
| KR (1) | KR20240069773A (https=) |
| CN (1) | CN118201915A (https=) |
| AR (1) | AR127108A1 (https=) |
| AU (1) | AU2022351219A1 (https=) |
| CA (1) | CA3232178A1 (https=) |
| MX (1) | MX2024003399A (https=) |
| TW (1) | TW202328102A (https=) |
| WO (1) | WO2023046698A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024180206A1 (en) * | 2023-03-02 | 2024-09-06 | Chiesi Farmaceutici S.P.A. | Pyridazinyl amino derivatives as alk5 inhibitors |
| WO2024180207A1 (en) | 2023-03-02 | 2024-09-06 | Chiesi Farmaceutici S.P.A. | Pyridazinyl amino derivatives as alk5 inhibitors |
| WO2025132458A1 (en) | 2023-12-18 | 2025-06-26 | Chiesi Farmaceutici S.P.A. | Pyridazinyl amino derivatives as alk5 inhibitors |
| WO2025132460A1 (en) | 2023-12-18 | 2025-06-26 | Chiesi Farmaceutici S.P.A. | Pyridazinyl amino derivatives as alk5 inhibitors |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR029803A1 (es) | 2000-02-21 | 2003-07-16 | Smithkline Beecham Plc | Imidazoles sustituidos con piridilo y composiciones farmaceuticas que las comprenden |
| GB0007405D0 (en) | 2000-03-27 | 2000-05-17 | Smithkline Beecham Corp | Compounds |
| EP1317450B1 (en) | 2000-09-15 | 2006-11-22 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| CA2423050A1 (en) | 2000-09-20 | 2002-03-28 | Ortho-Mcneil Pharmaceutical, Inc. | Pyrazine derivatives as modulators of tyrosine kinases |
| AR039241A1 (es) | 2002-04-04 | 2005-02-16 | Biogen Inc | Heteroarilos trisustituidos y metodos para su produccion y uso de los mismos |
| AU2004278382B2 (en) | 2003-09-30 | 2008-09-18 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| WO2005080377A1 (ja) * | 2004-02-20 | 2005-09-01 | Kirin Beer Kabushiki Kaisha | TGFβ阻害活性を有する化合物およびそれを含んでなる医薬組成物 |
| BRPI0714409A2 (pt) | 2006-07-14 | 2013-03-12 | Novartis Ag | derivados de pirimidina como inibidores de alk-5 |
| ES2375425T3 (es) | 2007-07-26 | 2012-02-29 | Novartis Ag | Compuestos org�?nicos. |
| BRPI0817434A2 (pt) | 2007-10-17 | 2015-06-16 | Novartis Ag | Composto orgânicos |
| AR070127A1 (es) | 2008-01-11 | 2010-03-17 | Novartis Ag | Pirrolo - pirimidinas y pirrolo -piridinas |
| MX2010007604A (es) | 2008-01-11 | 2010-08-02 | Novartis Ag | Pirimidinas como inhibidores de cinasa. |
| US8343966B2 (en) | 2008-01-11 | 2013-01-01 | Novartis Ag | Organic compounds |
| EA201001687A1 (ru) | 2008-04-29 | 2011-06-30 | Новартис Аг | Производные имидазопиридина в качестве ингибиторов активиноподобной рецепторной киназы ( alk-4 или alk-5 ) |
| US9073918B2 (en) * | 2010-05-20 | 2015-07-07 | Takeda Pharmaceutical Company Limited | Pyrazolo[4,3-b]pyridine-7-amine inhibitors of ALK5 |
| US20200247812A1 (en) * | 2018-07-10 | 2020-08-06 | Integral Biosciences Private Limited | Heterocyclic compounds and methods of use |
-
2022
- 2022-09-20 AU AU2022351219A patent/AU2022351219A1/en active Pending
- 2022-09-20 MX MX2024003399A patent/MX2024003399A/es unknown
- 2022-09-20 AR ARP220102539A patent/AR127108A1/es unknown
- 2022-09-20 JP JP2024517459A patent/JP2024534510A/ja not_active Withdrawn
- 2022-09-20 WO PCT/EP2022/076130 patent/WO2023046698A1/en not_active Ceased
- 2022-09-20 US US18/693,564 patent/US20250011299A1/en active Pending
- 2022-09-20 KR KR1020247013019A patent/KR20240069773A/ko not_active Withdrawn
- 2022-09-20 CN CN202280074135.5A patent/CN118201915A/zh active Pending
- 2022-09-20 EP EP22793401.5A patent/EP4405343A1/en active Pending
- 2022-09-20 CA CA3232178A patent/CA3232178A1/en active Pending
- 2022-09-20 TW TW111135435A patent/TW202328102A/zh unknown
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