JPWO2023039440A5 - - Google Patents
Info
- Publication number
- JPWO2023039440A5 JPWO2023039440A5 JP2024515069A JP2024515069A JPWO2023039440A5 JP WO2023039440 A5 JPWO2023039440 A5 JP WO2023039440A5 JP 2024515069 A JP2024515069 A JP 2024515069A JP 2024515069 A JP2024515069 A JP 2024515069A JP WO2023039440 A5 JPWO2023039440 A5 JP WO2023039440A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- mutation
- grna
- domain
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163241994P | 2021-09-08 | 2021-09-08 | |
| US63/241,994 | 2021-09-08 | ||
| US202163250143P | 2021-09-29 | 2021-09-29 | |
| US63/250,143 | 2021-09-29 | ||
| US202263303900P | 2022-01-27 | 2022-01-27 | |
| US63/303,900 | 2022-01-27 | ||
| PCT/US2022/076063 WO2023039440A2 (en) | 2021-09-08 | 2022-09-07 | Hbb-modulating compositions and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024533313A JP2024533313A (ja) | 2024-09-12 |
| JP2024533313A5 JP2024533313A5 (https=) | 2025-09-17 |
| JPWO2023039440A5 true JPWO2023039440A5 (https=) | 2025-09-17 |
Family
ID=85506910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024515069A Pending JP2024533313A (ja) | 2021-09-08 | 2022-09-07 | Ｈｂｂを調節する組成物及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240252682A1 (https=) |
| EP (1) | EP4399307A4 (https=) |
| JP (1) | JP2024533313A (https=) |
| AU (1) | AU2022342169A1 (https=) |
| CA (1) | CA3231679A1 (https=) |
| TW (1) | TW202323524A (https=) |
| WO (1) | WO2023039440A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150165054A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting caspase-9 point mutations |
| CN113286880A (zh) | 2018-08-28 | 2021-08-20 | 旗舰先锋创新Vi有限责任公司 | 调控基因组的方法和组合物 |
| CA3174483A1 (en) | 2020-03-04 | 2021-09-10 | Flagship Pioneering Innovations Vi, Llc | Improved methods and compositions for modulating a genome |
| IL296024A (en) | 2020-03-04 | 2022-10-01 | Flagship Pioneering Innovations Vi Llc | Methods and compositions for modulating a genome |
| DE112021002672T5 (de) | 2020-05-08 | 2023-04-13 | President And Fellows Of Harvard College | Vefahren und zusammensetzungen zum gleichzeitigen editieren beider stränge einer doppelsträngigen nukleotid-zielsequenz |
| KR20240099164A (ko) | 2021-09-08 | 2024-06-28 | 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 | Pah-조절 조성물 및 방법 |
| EP4684023A2 (en) * | 2023-03-21 | 2026-01-28 | Tessera Therapeutics, Inc. | Modified template guide rna molecules |
| WO2024206125A1 (en) * | 2023-03-24 | 2024-10-03 | The Broad Institute, Inc. | Use of prime editing for treating sickle cell disease |
| WO2025059607A1 (en) * | 2023-09-13 | 2025-03-20 | Tessera Therapeutics, Inc. | Lipid nanoparticles for delivery of therapeutic payloads to cells |
| WO2025128871A2 (en) | 2023-12-13 | 2025-06-19 | Renagade Therapeutics Management Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
| WO2025174765A1 (en) | 2024-02-12 | 2025-08-21 | Renagade Therapeutics Management Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3445388T3 (da) * | 2016-04-18 | 2024-06-03 | Vertex Pharma | Materialer og fremgangsmåder til behandling af hæmoglobinopatier |
| BR112019000057A2 (pt) * | 2016-07-05 | 2019-04-02 | The Johns Hopkins University | composições e métodos com base em crispr/cas9 para o tratamento de degeneração de retina |
| JP7657726B2 (ja) * | 2019-03-19 | 2025-04-07 | ザ ブロード インスティテュート，インコーポレーテッド | 編集ヌクレオチド配列を編集するための方法および組成物 |
| CN114667149A (zh) * | 2019-09-09 | 2022-06-24 | 比姆医疗股份有限公司 | 新型核碱基编辑器及其使用方法 |
| US12435330B2 (en) * | 2019-10-10 | 2025-10-07 | The Broad Institute, Inc. | Methods and compositions for prime editing RNA |
-
2022
- 2022-09-07 AU AU2022342169A patent/AU2022342169A1/en active Pending
- 2022-09-07 CA CA3231679A patent/CA3231679A1/en active Pending
- 2022-09-07 JP JP2024515069A patent/JP2024533313A/ja active Pending
- 2022-09-07 WO PCT/US2022/076063 patent/WO2023039440A2/en not_active Ceased
- 2022-09-07 EP EP22868285.2A patent/EP4399307A4/en active Pending
- 2022-09-08 TW TW111134206A patent/TW202323524A/zh unknown
-
2024
- 2024-02-28 US US18/590,275 patent/US20240252682A1/en active Pending
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