JP2024533313A5 - - Google Patents
Info
- Publication number
- JP2024533313A5 JP2024533313A5 JP2024515069A JP2024515069A JP2024533313A5 JP 2024533313 A5 JP2024533313 A5 JP 2024533313A5 JP 2024515069 A JP2024515069 A JP 2024515069A JP 2024515069 A JP2024515069 A JP 2024515069A JP 2024533313 A5 JP2024533313 A5 JP 2024533313A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- grna
- mutation
- gene
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163241994P | 2021-09-08 | 2021-09-08 | |
| US63/241,994 | 2021-09-08 | ||
| US202163250143P | 2021-09-29 | 2021-09-29 | |
| US63/250,143 | 2021-09-29 | ||
| US202263303900P | 2022-01-27 | 2022-01-27 | |
| US63/303,900 | 2022-01-27 | ||
| PCT/US2022/076063 WO2023039440A2 (en) | 2021-09-08 | 2022-09-07 | Hbb-modulating compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024533313A JP2024533313A (ja) | 2024-09-12 |
| JP2024533313A5 true JP2024533313A5 (https=) | 2025-09-17 |
Family
ID=85506910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024515069A Pending JP2024533313A (ja) | 2021-09-08 | 2022-09-07 | Ｈｂｂを調節する組成物及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240252682A1 (https=) |
| EP (1) | EP4399307A4 (https=) |
| JP (1) | JP2024533313A (https=) |
| AU (1) | AU2022342169A1 (https=) |
| CA (1) | CA3231679A1 (https=) |
| TW (1) | TW202323524A (https=) |
| WO (1) | WO2023039440A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150165054A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting caspase-9 point mutations |
| EP3844272A1 (en) | 2018-08-28 | 2021-07-07 | Flagship Pioneering Innovations VI, LLC | Methods and compositions for modulating a genome |
| CN116209756A (zh) | 2020-03-04 | 2023-06-02 | 旗舰先锋创新Vi有限责任公司 | 调控基因组的方法和组合物 |
| KR20230053735A (ko) | 2020-03-04 | 2023-04-21 | 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 | 게놈의 조정을 위한 개선된 방법 및 조성물 |
| IL297761A (en) | 2020-05-08 | 2022-12-01 | Broad Inst Inc | Methods and compositions for simultaneously editing two helices of a designated double-helix nucleotide sequence |
| CA3231712A1 (en) | 2021-09-08 | 2023-03-16 | Flagship Pioneering Innovations Vi, Llc | Pah-modulating compositions and methods |
| WO2024197103A2 (en) * | 2023-03-21 | 2024-09-26 | Tessera Therapeutics, Inc. | Modified template guide rna molecules |
| WO2024206125A1 (en) * | 2023-03-24 | 2024-10-03 | The Broad Institute, Inc. | Use of prime editing for treating sickle cell disease |
| WO2025059607A1 (en) * | 2023-09-13 | 2025-03-20 | Tessera Therapeutics, Inc. | Lipid nanoparticles for delivery of therapeutic payloads to cells |
| WO2025128871A2 (en) | 2023-12-13 | 2025-06-19 | Renagade Therapeutics Management Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
| WO2025174765A1 (en) | 2024-02-12 | 2025-08-21 | Renagade Therapeutics Management Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017252023B2 (en) * | 2016-04-18 | 2024-05-02 | Vertex Pharmaceuticals Incorporated | Materials and methods for treatment of hemoglobinopathies |
| KR20190039703A (ko) * | 2016-07-05 | 2019-04-15 | 더 존스 홉킨스 유니버시티 | Crispr/cas9-기반 조성물 및 망막 변성을 치료하기 위한 방법 |
| WO2020191233A1 (en) * | 2019-03-19 | 2020-09-24 | The Broad Institute, Inc. | Methods and compositions for editing nucleotide sequences |
| AU2020344547A1 (en) * | 2019-09-09 | 2022-03-24 | Beam Therapeutics Inc. | Novel nucleobase editors and methods of using same |
| US12435330B2 (en) * | 2019-10-10 | 2025-10-07 | The Broad Institute, Inc. | Methods and compositions for prime editing RNA |
-
2022
- 2022-09-07 CA CA3231679A patent/CA3231679A1/en active Pending
- 2022-09-07 WO PCT/US2022/076063 patent/WO2023039440A2/en not_active Ceased
- 2022-09-07 EP EP22868285.2A patent/EP4399307A4/en active Pending
- 2022-09-07 AU AU2022342169A patent/AU2022342169A1/en active Pending
- 2022-09-07 JP JP2024515069A patent/JP2024533313A/ja active Pending
- 2022-09-08 TW TW111134206A patent/TW202323524A/zh unknown
-
2024
- 2024-02-28 US US18/590,275 patent/US20240252682A1/en active Pending
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