JPWO2023025193A5 - - Google Patents
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- JPWO2023025193A5 JPWO2023025193A5 JP2024536342A JP2024536342A JPWO2023025193A5 JP WO2023025193 A5 JPWO2023025193 A5 JP WO2023025193A5 JP 2024536342 A JP2024536342 A JP 2024536342A JP 2024536342 A JP2024536342 A JP 2024536342A JP WO2023025193 A5 JPWO2023025193 A5 JP WO2023025193A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- vector
- recombinant protein
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110981721.5 | 2021-08-25 | ||
| CN202110981721 | 2021-08-25 | ||
| PCT/CN2022/114516 WO2023025193A1 (zh) | 2021-08-25 | 2022-08-24 | 神经生长因子突变体重组蛋白及其应用 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2024532596A JP2024532596A (ja) | 2024-09-05 |
| JPWO2023025193A5 true JPWO2023025193A5 (https=) | 2024-09-19 |
| JP2024532596A5 JP2024532596A5 (https=) | 2024-09-19 |
| JP7687643B2 JP7687643B2 (ja) | 2025-06-03 |
Family
ID=82862610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024536342A Active JP7687643B2 (ja) | 2021-08-25 | 2022-08-24 | 神経成長因子突然変異体の組換えタンパク質及びその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250009846A1 (https=) |
| EP (1) | EP4375367B1 (https=) |
| JP (1) | JP7687643B2 (https=) |
| CN (1) | CN114933657B (https=) |
| WO (1) | WO2023025193A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114933657B (zh) * | 2021-08-25 | 2024-02-02 | 上海交通大学医学院 | 神经生长因子突变体重组蛋白及其应用 |
| WO2024189146A1 (en) * | 2023-03-15 | 2024-09-19 | Versameb Ag | Rna encoding a protein |
| WO2025130564A1 (zh) * | 2023-12-20 | 2025-06-26 | 广州市恒诺康医药科技有限公司 | 编码神经生长因子(NGF)的mRNA及其组合物和应用 |
| WO2025184345A1 (en) * | 2024-02-27 | 2025-09-04 | Ohio State Innovation Foundation | Methods and compositions for treating neuropathy |
| EP4623927A1 (en) * | 2024-03-27 | 2025-10-01 | Dompe' Farmaceutici SpA | Ngf for use in the prevention or treatment of motor impairment caused by neonatal hypoxic-ischemic encephalopathy |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602005010047D1 (de) * | 2004-01-19 | 2008-11-13 | Nsgene As | Nervenwachstumsfaktor sezernierende menschliche therapeutische zellen |
| EP2048237A1 (en) | 2007-10-05 | 2009-04-15 | Avir Green Hills Biotechnology Research Development Trade Ag | Replication deficient Influenza virus for the expression of heterologous sequences |
| WO2009114702A2 (en) * | 2008-03-14 | 2009-09-17 | Humanzyme Limited | Recombinant production of authentic human proteins using human cell expression systems |
| JP5799397B2 (ja) * | 2008-06-12 | 2015-10-28 | イプセン・バイオイノベーション・リミテッドＩｐｓｅｎ Ｂｉｏｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ | 癌の抑制 |
| EP2367564A1 (en) * | 2008-12-22 | 2011-09-28 | Universität Regensburg | Norrin in the treatment of diseases associated with an increased tgf-beta activity |
| AU2010206374B2 (en) * | 2009-01-23 | 2013-01-17 | Gloriana Therapeutics Sarl | Improved cell lines and their use in encapsulated cell biodelivery |
| AU2012205583B2 (en) | 2011-01-11 | 2016-01-21 | Fate Therapeutics, Inc. | Novel Wnt compositions and therapeutic uses of such compositions |
| WO2012170452A2 (en) * | 2011-06-06 | 2012-12-13 | The Regents Of The University Of California | Compositions and methods for treating neurodegenerative diseases |
| CN106008722B (zh) * | 2016-05-13 | 2019-10-15 | 未名生物医药有限公司 | 一种重组β-hNGF-Fc融合蛋白、制备方法及用途 |
| CN108178798B (zh) * | 2016-12-08 | 2021-03-30 | 苏州方德门达新药开发有限公司 | pH工程化的NGF抗体及其医药用途 |
| JP2020507350A (ja) * | 2017-02-10 | 2020-03-12 | ヴィヴィババ インコーポレイテッド | 組換え神経成長因子のための組成物及び方法 |
| GB201705484D0 (en) * | 2017-04-05 | 2017-05-17 | Quethera Ltd | Genetic construct |
| CN108314723A (zh) * | 2018-01-11 | 2018-07-24 | 温州医科大学 | 一种人源突变型神经生长因子及其制备方法和应用 |
| CN108610398B (zh) * | 2018-01-15 | 2020-08-11 | 武汉海特生物制药股份有限公司 | 一段功能序列及在分泌蛋白表达中的应用 |
| BR112022016197A2 (pt) | 2020-02-14 | 2022-10-25 | Univ Washington | Polipeptídeos e seus usos |
| CN112794893A (zh) | 2021-01-29 | 2021-05-14 | 华中农业大学 | 一种捻转血矛线虫Hc-H11-2重组蛋白的构建方法及其应用 |
| CN114933657B (zh) * | 2021-08-25 | 2024-02-02 | 上海交通大学医学院 | 神经生长因子突变体重组蛋白及其应用 |
-
2022
- 2022-02-17 CN CN202210147754.4A patent/CN114933657B/zh active Active
- 2022-08-24 EP EP22860539.0A patent/EP4375367B1/en active Active
- 2022-08-24 US US18/686,041 patent/US20250009846A1/en not_active Abandoned
- 2022-08-24 WO PCT/CN2022/114516 patent/WO2023025193A1/zh not_active Ceased
- 2022-08-24 JP JP2024536342A patent/JP7687643B2/ja active Active
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