JP2024532596A5 - - Google Patents

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Publication number
JP2024532596A5
JP2024532596A5 JP2024536342A JP2024536342A JP2024532596A5 JP 2024532596 A5 JP2024532596 A5 JP 2024532596A5 JP 2024536342 A JP2024536342 A JP 2024536342A JP 2024536342 A JP2024536342 A JP 2024536342A JP 2024532596 A5 JP2024532596 A5 JP 2024532596A5
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Japan
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JP2024536342A
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JPWO2023025193A5 (https=
JP7687643B2 (ja
JP2024532596A (ja
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JP2024536342A 2021-08-25 2022-08-24 神経成長因子突然変異体の組換えタンパク質及びその使用 Active JP7687643B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110981721.5 2021-08-25
CN202110981721 2021-08-25
PCT/CN2022/114516 WO2023025193A1 (zh) 2021-08-25 2022-08-24 神经生长因子突变体重组蛋白及其应用

Publications (4)

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JP2024532596A JP2024532596A (ja) 2024-09-05
JPWO2023025193A5 JPWO2023025193A5 (https=) 2024-09-19
JP2024532596A5 true JP2024532596A5 (https=) 2024-09-19
JP7687643B2 JP7687643B2 (ja) 2025-06-03

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US (1) US20250009846A1 (https=)
EP (1) EP4375367B1 (https=)
JP (1) JP7687643B2 (https=)
CN (1) CN114933657B (https=)
WO (1) WO2023025193A1 (https=)

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Publication number Priority date Publication date Assignee Title
CN114933657B (zh) * 2021-08-25 2024-02-02 上海交通大学医学院 神经生长因子突变体重组蛋白及其应用
WO2024189146A1 (en) * 2023-03-15 2024-09-19 Versameb Ag Rna encoding a protein
WO2025130564A1 (zh) * 2023-12-20 2025-06-26 广州市恒诺康医药科技有限公司 编码神经生长因子(NGF)的mRNA及其组合物和应用
WO2025184345A1 (en) * 2024-02-27 2025-09-04 Ohio State Innovation Foundation Methods and compositions for treating neuropathy
EP4623927A1 (en) * 2024-03-27 2025-10-01 Dompe' Farmaceutici SpA Ngf for use in the prevention or treatment of motor impairment caused by neonatal hypoxic-ischemic encephalopathy

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DE602005010047D1 (de) * 2004-01-19 2008-11-13 Nsgene As Nervenwachstumsfaktor sezernierende menschliche therapeutische zellen
EP2048237A1 (en) 2007-10-05 2009-04-15 Avir Green Hills Biotechnology Research Development Trade Ag Replication deficient Influenza virus for the expression of heterologous sequences
WO2009114702A2 (en) * 2008-03-14 2009-09-17 Humanzyme Limited Recombinant production of authentic human proteins using human cell expression systems
JP5799397B2 (ja) * 2008-06-12 2015-10-28 イプセン・バイオイノベーション・リミテッドIpsen Bioinnovation Limited 癌の抑制
EP2367564A1 (en) * 2008-12-22 2011-09-28 Universität Regensburg Norrin in the treatment of diseases associated with an increased tgf-beta activity
AU2010206374B2 (en) * 2009-01-23 2013-01-17 Gloriana Therapeutics Sarl Improved cell lines and their use in encapsulated cell biodelivery
AU2012205583B2 (en) 2011-01-11 2016-01-21 Fate Therapeutics, Inc. Novel Wnt compositions and therapeutic uses of such compositions
WO2012170452A2 (en) * 2011-06-06 2012-12-13 The Regents Of The University Of California Compositions and methods for treating neurodegenerative diseases
CN106008722B (zh) * 2016-05-13 2019-10-15 未名生物医药有限公司 一种重组β-hNGF-Fc融合蛋白、制备方法及用途
CN108178798B (zh) * 2016-12-08 2021-03-30 苏州方德门达新药开发有限公司 pH工程化的NGF抗体及其医药用途
JP2020507350A (ja) * 2017-02-10 2020-03-12 ヴィヴィババ インコーポレイテッド 組換え神経成長因子のための組成物及び方法
GB201705484D0 (en) * 2017-04-05 2017-05-17 Quethera Ltd Genetic construct
CN108314723A (zh) * 2018-01-11 2018-07-24 温州医科大学 一种人源突变型神经生长因子及其制备方法和应用
CN108610398B (zh) * 2018-01-15 2020-08-11 武汉海特生物制药股份有限公司 一段功能序列及在分泌蛋白表达中的应用
BR112022016197A2 (pt) 2020-02-14 2022-10-25 Univ Washington Polipeptídeos e seus usos
CN112794893A (zh) 2021-01-29 2021-05-14 华中农业大学 一种捻转血矛线虫Hc-H11-2重组蛋白的构建方法及其应用
CN114933657B (zh) * 2021-08-25 2024-02-02 上海交通大学医学院 神经生长因子突变体重组蛋白及其应用

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