JPWO2023004409A5 - - Google Patents
Info
- Publication number
- JPWO2023004409A5 JPWO2023004409A5 JP2024504461A JP2024504461A JPWO2023004409A5 JP WO2023004409 A5 JPWO2023004409 A5 JP WO2023004409A5 JP 2024504461 A JP2024504461 A JP 2024504461A JP 2024504461 A JP2024504461 A JP 2024504461A JP WO2023004409 A5 JPWO2023004409 A5 JP WO2023004409A5
- Authority
- JP
- Japan
- Prior art keywords
- grna
- amino acid
- acid position
- composition
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163225322P | 2021-07-23 | 2021-07-23 | |
| US63/225,322 | 2021-07-23 | ||
| US202163255927P | 2021-10-14 | 2021-10-14 | |
| US63/255,927 | 2021-10-14 | ||
| PCT/US2022/074041 WO2023004409A1 (en) | 2021-07-23 | 2022-07-22 | Guide rnas for crispr/cas editing systems |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024529425A JP2024529425A (ja) | 2024-08-06 |
| JPWO2023004409A5 true JPWO2023004409A5 (https=) | 2025-07-18 |
| JP2024529425A5 JP2024529425A5 (https=) | 2025-07-18 |
Family
ID=83149172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024504461A Pending JP2024529425A (ja) | 2021-07-23 | 2022-07-22 | ＣＲＩＳＰＲ／Ｃａｓ編集系のためのガイドＲＮＡ |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240301405A1 (https=) |
| EP (1) | EP4373931A1 (https=) |
| JP (1) | JP2024529425A (https=) |
| KR (1) | KR20240037299A (https=) |
| AU (1) | AU2022313315A1 (https=) |
| CA (1) | CA3226664A1 (https=) |
| WO (1) | WO2023004409A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230383277A1 (en) * | 2020-10-14 | 2023-11-30 | Beam Therapeutics Inc. | Compositions and methods for treating glycogen storage disease type 1a |
| WO2024220980A2 (en) * | 2023-04-20 | 2024-10-24 | The Schepens Eye Research Institute, Inc. | Dscam inhibitory nucleic acids and methods of use thereof |
| IL324634A (en) | 2023-05-15 | 2026-01-01 | Nchroma Bio Inc | Compositions and methods for epigenetic regulation of hbv gene expression |
| WO2025087411A1 (zh) * | 2023-10-25 | 2025-05-01 | 尧唐(上海)生物科技有限公司 | 一种脱氨酶、包含其的碱基编辑器及其应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4880635B1 (en) | 1984-08-08 | 1996-07-02 | Liposome Company | Dehydrated liposomes |
| US4921757A (en) | 1985-04-26 | 1990-05-01 | Massachusetts Institute Of Technology | System for delayed and pulsed release of biologically active substances |
| US4920016A (en) | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
| JPH0825869B2 (ja) | 1987-02-09 | 1996-03-13 | 株式会社ビタミン研究所 | 抗腫瘍剤包埋リポソ−ム製剤 |
| US4911928A (en) | 1987-03-13 | 1990-03-27 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
| US4917951A (en) | 1987-07-28 | 1990-04-17 | Micro-Pak, Inc. | Lipid vesicles formed of surfactants and steroids |
| US5846946A (en) | 1996-06-14 | 1998-12-08 | Pasteur Merieux Serums Et Vaccins | Compositions and methods for administering Borrelia DNA |
| JP4772045B2 (ja) | 2004-07-16 | 2011-09-14 | アメリカ合衆国 | Ｃｍｖ／ｒ核酸コンストラクトを含むａｉｄｓに対するワクチン |
| WO2009088786A1 (en) | 2007-12-31 | 2009-07-16 | Nanocor Therapeutics, Inc. | Rna interference for the treatment of heart failure |
| EP3241902B1 (en) | 2012-05-25 | 2018-02-28 | The Regents of The University of California | Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription |
| CN105139759B (zh) | 2015-09-18 | 2017-10-10 | 京东方科技集团股份有限公司 | 一种拼接屏 |
| WO2017058751A1 (en) * | 2015-09-28 | 2017-04-06 | North Carolina State University | Methods and compositions for sequence specific antimicrobials |
| JP7109784B2 (ja) | 2015-10-23 | 2022-08-01 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 遺伝子編集のための進化したＣａｓ９蛋白質 |
| KR102547316B1 (ko) | 2016-08-03 | 2023-06-23 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 아데노신 핵염기 편집제 및 그의 용도 |
| EP3829597A4 (en) * | 2018-07-30 | 2022-05-18 | Sarepta Therapeutics, Inc. | TRIMER PEPTIDES FOR ANTISENSE ADMINISTRATION |
| JP2020038883A (ja) | 2018-09-03 | 2020-03-12 | 株式会社オートネットワーク技術研究所 | 回路構造体及び回路構造体の製造方法 |
| AU2020352931A1 (en) * | 2019-09-23 | 2022-03-31 | Flagship Pioneering Innovations V, Inc. | Modulating genomic complexes |
| US20230020092A1 (en) * | 2019-12-19 | 2023-01-19 | Entrada Therapeutics, Inc. | Compositions for delivery of antisense compounds |
-
2022
- 2022-07-22 AU AU2022313315A patent/AU2022313315A1/en active Pending
- 2022-07-22 CA CA3226664A patent/CA3226664A1/en active Pending
- 2022-07-22 JP JP2024504461A patent/JP2024529425A/ja active Pending
- 2022-07-22 WO PCT/US2022/074041 patent/WO2023004409A1/en not_active Ceased
- 2022-07-22 KR KR1020247005580A patent/KR20240037299A/ko active Pending
- 2022-07-22 EP EP22761858.4A patent/EP4373931A1/en active Pending
-
2024
- 2024-01-22 US US18/418,751 patent/US20240301405A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20240309373A1 (en) | SPECIFIC SYNTHETIC CHIMERIC XENONUCLEIC ACID GUIDE RNA; s(XNA-gRNA) FOR ENHANCING CRISPR MEDIATED GENOME EDITING EFFICIENCY | |
| CN110291198B (zh) | 经修饰的指导rna | |
| Kos et al. | Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer | |
| JP2025081309A5 (https=) | ||
| Guy et al. | Delivery of DNA into mammalian cells by receptor-mediated endocytosis and gene therapy | |
| Chen et al. | Galactosylated histone-mediated gene transfer and expression | |
| WO2006085664A1 (ja) | ポリカチオン荷電性ポリマー及び核酸のキャリヤーとしての使用 | |
| JPWO2023015309A5 (https=) | ||
| CN111757889A (zh) | 新型CRISPR/Cas12f酶和系统 | |
| KR20250051155A (ko) | 범용 공여자 세포 | |
| JPWO2021050571A5 (https=) | ||
| JP2021500072A (ja) | 血友病ａに対する遺伝子編集用組成物及び方法 | |
| RS62523B1 (sr) | Kompozicije i postupci za inhibiciju genske ekspresije lpa | |
| JPWO2019237069A5 (https=) | ||
| CN113811611A (zh) | 无毒cas9酶及其应用 | |
| KR20180015731A (ko) | 캄필로박터 제주니 crispr/cas 시스템 유래 rgen을 이용한 유전체 교정 | |
| KR20160089530A (ko) | Ｈｂｖ 및 바이러스 질병 및 질환을 위한 ｃｒｉｓｐｒｃａｓ 시스템 및 조성물의 전달，용도 및 치료적 적용 | |
| JPWO2021030344A5 (https=) | ||
| EP1272222A2 (en) | Compositions for drug delivery | |
| Severi et al. | CRISPR‐Cas9 delivery strategies and applications: Review and update | |
| CA2435712A1 (en) | Universal carrier for targeting molecules to gb3 receptor expressing cells | |
| JPWO2023004409A5 (https=) | ||
| JPWO2020223514A5 (https=) | ||
| WO2000043043B1 (en) | Ligand-peg post-coating stabilized lipoplex and polyplex for targeted gene delivery | |
| JPWO2022256440A5 (https=) |