JPWO2022261490A5 - - Google Patents
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- Publication number
- JPWO2022261490A5 JPWO2022261490A5 JP2023576064A JP2023576064A JPWO2022261490A5 JP WO2022261490 A5 JPWO2022261490 A5 JP WO2022261490A5 JP 2023576064 A JP2023576064 A JP 2023576064A JP 2023576064 A JP2023576064 A JP 2023576064A JP WO2022261490 A5 JPWO2022261490 A5 JP WO2022261490A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- sequence
- item
- fragment
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163209271P | 2021-06-10 | 2021-06-10 | |
| US63/209,271 | 2021-06-10 | ||
| US202263311923P | 2022-02-18 | 2022-02-18 | |
| US63/311,923 | 2022-02-18 | ||
| PCT/US2022/033091 WO2022261490A2 (en) | 2021-06-10 | 2022-06-10 | Circular rna compositions and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024521444A JP2024521444A (ja) | 2024-05-31 |
| JPWO2022261490A5 true JPWO2022261490A5 (https=) | 2025-06-06 |
| JP2024521444A5 JP2024521444A5 (https=) | 2025-06-06 |
Family
ID=83081188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023576064A Pending JP2024521444A (ja) | 2021-06-10 | 2022-06-10 | 環状ｒｎａ組成物及び方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250283073A1 (https=) |
| EP (1) | EP4352234A2 (https=) |
| JP (1) | JP2024521444A (https=) |
| KR (1) | KR20240019791A (https=) |
| AU (1) | AU2022288705A1 (https=) |
| BR (1) | BR112023025515A2 (https=) |
| CA (1) | CA3219932A1 (https=) |
| IL (1) | IL308746A (https=) |
| MX (1) | MX2023014702A (https=) |
| TW (1) | TW202317767A (https=) |
| WO (1) | WO2022261490A2 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2994006T3 (en) | 2021-09-17 | 2025-01-16 | Flagship Pioneering Innovations Vi Llc | Compositions and methods for producing circular polyribonucleotides |
| CN114214237B (zh) * | 2021-12-23 | 2023-06-16 | 南京大学 | 一种洗脱细胞表面吸附纳米颗粒的方法 |
| CN119110847A (zh) * | 2022-01-11 | 2024-12-10 | 北京大学 | 针对sars-cov-2变体的环状rna疫苗及其使用方法 |
| WO2023141586A1 (en) * | 2022-01-21 | 2023-07-27 | Orna Therapeutics, Inc. | Systemic administration of circular rna polynucleotides encoding muscle proteins or protein complexes |
| CN118871134A (zh) * | 2022-03-21 | 2024-10-29 | 生物探险有限公司 | 用于增强蛋白质表达的内部核糖体进入位点（IRES）、质粒载体和环状mRNA |
| US12297285B2 (en) * | 2022-06-24 | 2025-05-13 | Orna Therapeutics, Inc. | Circular RNA encoding chimeric antigen receptors targeting BCMA |
| CN116064531B (zh) * | 2022-09-07 | 2024-04-02 | 昆明理工大学 | 一种抑制cvb5病毒复制的长链非编码rna及应用 |
| CN120390656A (zh) | 2022-11-08 | 2025-07-29 | 欧纳医疗公司 | 环状rna组合物 |
| AU2023398825A1 (en) | 2022-12-15 | 2025-06-26 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| WO2024192420A1 (en) | 2023-03-15 | 2024-09-19 | Flagship Pioneering Innovations Vi, Llc | Compositions comprising polyribonucleotides and uses thereof |
| EP4680276A1 (en) | 2023-03-15 | 2026-01-21 | Flagship Pioneering Innovations VI, LLC | Immunogenic compositions and uses thereof |
| KR20240159310A (ko) * | 2023-04-28 | 2024-11-05 | 주식회사 메디치바이오 | 신규한 이온화지질을 이용한 지질나노입자 조성물 |
| WO2024205657A2 (en) * | 2023-03-29 | 2024-10-03 | Orna Therapeutics, Inc. | Lipids and lipid nanoparticle compositions for delivering polynucleotides |
| CN121358499A (zh) | 2023-03-30 | 2026-01-16 | Ose免疫疗法 | 靶向活化的免疫细胞以表达免疫细胞增强分子的基于脂质的纳米粒及其用途 |
| AU2024254671A1 (en) | 2023-03-30 | 2025-10-02 | Ose Immunotherapeutics | Method of synthesis of targeted lipid nanoparticle and uses thereof |
| WO2024220752A2 (en) | 2023-04-19 | 2024-10-24 | Sail Biomedicines, Inc. | Rna therapeutic compositions |
| WO2024220712A2 (en) | 2023-04-19 | 2024-10-24 | Sail Biomedicines, Inc. | Vaccine compositions |
| EP4698150A1 (en) | 2023-04-19 | 2026-02-25 | Sail Biomedicines, Inc. | Delivery of polynucleotides from lipid nanoparticles comprising rna and ionizable lipids |
| WO2024233308A2 (en) | 2023-05-05 | 2024-11-14 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| US12311033B2 (en) | 2023-05-31 | 2025-05-27 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025006613A1 (en) * | 2023-06-27 | 2025-01-02 | Hopewell Therapeutics, Inc. | Lipid nanoparticles for cancer immunotherapy |
| WO2025007148A1 (en) | 2023-06-30 | 2025-01-02 | Orna Therapeutics, Inc. | Polymer lipid nanoparticle compositions for delivering circular polynucleotides |
| WO2025036467A1 (en) * | 2023-08-17 | 2025-02-20 | Wuhan University | Circular rna with increased stability and expression |
| WO2025049690A1 (en) | 2023-08-29 | 2025-03-06 | Orna Therapeutics, Inc. | Circular polyethylene glycol lipids |
| AU2024335327A1 (en) | 2023-09-01 | 2026-03-26 | Renagade Therapeutics Management Inc. | Gene editing systems, compositions, and methods for treatment of vexas syndrome |
| WO2025101501A1 (en) | 2023-11-07 | 2025-05-15 | Orna Therapeutics, Inc. | Circular rna compositions |
| WO2025106915A1 (en) | 2023-11-17 | 2025-05-22 | Sail Biomedicines, Inc. | Circular polyribonucleotides encoding glucagon-like peptide 1 (glp-1) and uses thereof |
| WO2025106930A1 (en) | 2023-11-17 | 2025-05-22 | Sail Biomedicines, Inc. | Circular polyribonucleotides encoding glucagon-like peptide 2 (glp-2) and uses thereof |
| WO2025117969A1 (en) | 2023-12-01 | 2025-06-05 | Orna Therapeutics, Inc. | Process for manufacturing lipid nanoparticles |
| WO2025128871A2 (en) | 2023-12-13 | 2025-06-19 | Renagade Therapeutics Management Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
| WO2025133115A1 (en) | 2023-12-21 | 2025-06-26 | Ose Immunotherapeutics | Lipid-based nanoparticles comprising il-35 |
| WO2025149040A1 (zh) * | 2024-01-11 | 2025-07-17 | 深圳近邻生物科技有限公司 | 一种通用的且无"scar"的RNA环化方法 |
| WO2025155753A2 (en) | 2024-01-17 | 2025-07-24 | Renagade Therapeutics Management Inc. | Improved gene editing system, guides, and methods |
| WO2025166238A1 (en) | 2024-01-31 | 2025-08-07 | Orna Therapeutics, Inc. | Fast-shedding polyethylene glycol lipids |
| WO2025179198A1 (en) | 2024-02-23 | 2025-08-28 | Sail Biomedicines, Inc. | Circular polyribonucleotides and unmodified linear rnas with reduced immunogenicity |
| WO2025218812A1 (en) * | 2024-04-19 | 2025-10-23 | Shanghai Circode Biomed Co., Ltd. | Novel internal ribosome entry sites and uses thereof |
| WO2025250751A1 (en) | 2024-05-31 | 2025-12-04 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| CN118703488A (zh) * | 2024-06-20 | 2024-09-27 | 毕昇(北京)生物科技有限公司 | 一种环状rna的纯化方法 |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
| WO2026006593A1 (en) | 2024-06-28 | 2026-01-02 | Orna Therapeutics, Inc. | Synthetic internal ribosome entry sites |
| WO2026072709A1 (en) | 2024-09-25 | 2026-04-02 | Orna Therapeutics, Inc. | Chimeric antigen receptors targeting bcma |
| WO2026068705A1 (en) | 2024-09-26 | 2026-04-02 | Ose Immunotherapeutics | Lipid-based nanoparticles comprising non-glycosylated fc domains and uses thereof |
| CN119876152A (zh) * | 2025-02-10 | 2025-04-25 | 毕昇(北京)生物科技有限公司 | 一种环状rna、嵌合抗原受体t细胞和构建方法及应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6319494B1 (en) | 1990-12-14 | 2001-11-20 | Cell Genesys, Inc. | Chimeric chains for receptor-associated signal transduction pathways |
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| IL135578A0 (en) | 1997-10-29 | 2001-05-20 | Genzyme Corp | Compositions and methods for treating lysosomal storage disease |
| US5948902A (en) | 1997-11-20 | 1999-09-07 | South Alabama Medical Science Foundation | Antisense oligonucleotides to human serine/threonine protein phosphatase genes |
| CA2400634A1 (en) | 2000-02-17 | 2001-08-23 | Chester Li | Genetic modification of the lung as a portal for gene delivery |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| US20040014194A1 (en) | 2002-03-27 | 2004-01-22 | Schering Corporation | Beta-secretase crystals and methods for preparing and using the same |
| US8361794B2 (en) | 2004-06-29 | 2013-01-29 | Immunocore Limited | Cells expressing a modified T cell receptor |
| ES2895651T3 (es) | 2013-12-19 | 2022-02-22 | Novartis Ag | Lípidos y composiciones lipídicas para la administración de agentes activos |
| EP4286012A3 (en) | 2015-09-17 | 2024-05-29 | ModernaTX, Inc. | Compounds and compositions for intracellular delivery of therapeutic agents |
| IL307179A (en) | 2015-10-28 | 2023-11-01 | Acuitas Therapeutics Inc | Novel lipids and lipid nanoparticle formulations for delivery of nucleic acids |
| EP3472193A4 (en) * | 2016-06-20 | 2020-01-08 | The Board of Trustees of the Leland Stanford Junior University | CIRCULAR RNA AND THEIR USE IN IMMUNOMODULATION |
| WO2019081383A1 (en) | 2017-10-25 | 2019-05-02 | Universität Zürich | EUCARYOTE 4 INITIATION FACTOR RECRUITMENT APTAMERS FOR ENHANCED TRANSLATION |
| JP2021512090A (ja) | 2018-01-30 | 2021-05-13 | モデルナティーエックス， インコーポレイテッド | 免疫細胞に薬剤を送達するための組成物及び方法 |
| CN111954542A (zh) | 2018-02-01 | 2020-11-17 | 塔夫茨大学信托人 | 脂质样纳米复合物及其用途 |
| US12083224B2 (en) | 2018-03-30 | 2024-09-10 | Arcturus Therapeutics, Inc. | Lipid particles for nucleic acid delivery |
| CA3100276A1 (en) * | 2018-06-06 | 2019-12-12 | Massachusetts Institute Of Technology | Circular rna for translation in eukaryotic cells |
| WO2020237227A1 (en) * | 2019-05-22 | 2020-11-26 | Massachusetts Institute Of Technology | Circular rna compositions and methods |
-
2022
- 2022-06-10 TW TW111121745A patent/TW202317767A/zh unknown
- 2022-06-10 CA CA3219932A patent/CA3219932A1/en active Pending
- 2022-06-10 AU AU2022288705A patent/AU2022288705A1/en active Pending
- 2022-06-10 IL IL308746A patent/IL308746A/en unknown
- 2022-06-10 US US18/567,469 patent/US20250283073A1/en active Pending
- 2022-06-10 EP EP22760801.5A patent/EP4352234A2/en active Pending
- 2022-06-10 WO PCT/US2022/033091 patent/WO2022261490A2/en not_active Ceased
- 2022-06-10 KR KR1020247000046A patent/KR20240019791A/ko active Pending
- 2022-06-10 BR BR112023025515A patent/BR112023025515A2/pt unknown
- 2022-06-10 MX MX2023014702A patent/MX2023014702A/es unknown
- 2022-06-10 JP JP2023576064A patent/JP2024521444A/ja active Pending
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