JPWO2022197789A5 - - Google Patents
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- Publication number
- JPWO2022197789A5 JPWO2022197789A5 JP2023557370A JP2023557370A JPWO2022197789A5 JP WO2022197789 A5 JPWO2022197789 A5 JP WO2022197789A5 JP 2023557370 A JP2023557370 A JP 2023557370A JP 2023557370 A JP2023557370 A JP 2023557370A JP WO2022197789 A5 JPWO2022197789 A5 JP WO2022197789A5
- Authority
- JP
- Japan
- Prior art keywords
- independently selected
- compound
- nitrogen
- sulfur
- oxygen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163162483P | 2021-03-17 | 2021-03-17 | |
| US63/162,483 | 2021-03-17 | ||
| PCT/US2022/020527 WO2022197789A1 (en) | 2021-03-17 | 2022-03-16 | Polycyclic inhibitors of plasma kallikrein |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024510504A JP2024510504A (ja) | 2024-03-07 |
| JPWO2022197789A5 true JPWO2022197789A5 (https=) | 2025-03-25 |
| JP2024510504A5 JP2024510504A5 (https=) | 2025-03-25 |
Family
ID=81328648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023557370A Pending JP2024510504A (ja) | 2021-03-17 | 2022-03-16 | 血漿カリクレインの多環式インヒビター |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240199613A1 (https=) |
| EP (1) | EP4308564A1 (https=) |
| JP (1) | JP2024510504A (https=) |
| CN (1) | CN117355523A (https=) |
| WO (1) | WO2022197789A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200143376A (ko) | 2018-03-13 | 2020-12-23 | 샤이어 휴먼 지네틱 테라피즈 인크. | 혈장 칼리크레인 억제제로서의 치환된 이미다조피리딘 및 이의 용도 |
| CN114667289B (zh) | 2019-09-18 | 2025-08-26 | 武田药品工业有限公司 | 杂芳基血浆激肽释放酶抑制剂 |
| EP4031547B1 (en) | 2019-09-18 | 2024-07-17 | Takeda Pharmaceutical Company Limited | Plasma kallikrein inhibitors and uses thereof |
| CN118239959A (zh) * | 2022-12-23 | 2024-06-25 | 上海深势唯思科技有限责任公司 | 环丙烷类tlr7和8抑制剂及其制备方法和用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| ATE141502T1 (de) | 1991-01-15 | 1996-09-15 | Alcon Lab Inc | Verwendung von karrageenan in topischen ophthalmologischen zusammensetzungen |
| US5212162A (en) | 1991-03-27 | 1993-05-18 | Alcon Laboratories, Inc. | Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions |
| US6309853B1 (en) | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| NZ526472A (en) * | 2000-12-21 | 2004-04-30 | Vertex Pharma | Pyrazole compounds useful as protein kinase inhibitors |
| CA2569406A1 (en) * | 2004-06-04 | 2005-12-22 | Icos Corporation | Methods for treating mast cell disorders |
| KR20080080584A (ko) * | 2005-11-30 | 2008-09-04 | 버텍스 파마슈티칼스 인코포레이티드 | ｃ-Ｍｅｔ의 억제제 및 이의 용도 |
| WO2013052526A1 (en) * | 2011-10-06 | 2013-04-11 | Merck Sharp & Dohme Corp. | Triazolyl pde10 inhibitors |
| JP6280546B2 (ja) * | 2012-06-26 | 2018-02-14 | デル マー ファーマシューティカルズ | ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はａｈｉ１の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法 |
| CN104059069B (zh) * | 2013-08-22 | 2016-08-10 | 北京康立生医药技术开发有限公司 | 一种替卡格雷的制备方法 |
| WO2015164308A1 (en) * | 2014-04-22 | 2015-10-29 | Merck Sharp & Dohme Corp. | FACTOR XIa INHIBITORS |
| KR20200143376A (ko) | 2018-03-13 | 2020-12-23 | 샤이어 휴먼 지네틱 테라피즈 인크. | 혈장 칼리크레인 억제제로서의 치환된 이미다조피리딘 및 이의 용도 |
-
2022
- 2022-03-16 EP EP22715248.5A patent/EP4308564A1/en active Pending
- 2022-03-16 WO PCT/US2022/020527 patent/WO2022197789A1/en not_active Ceased
- 2022-03-16 CN CN202280033914.0A patent/CN117355523A/zh active Pending
- 2022-03-16 JP JP2023557370A patent/JP2024510504A/ja active Pending
- 2022-03-16 US US18/550,486 patent/US20240199613A1/en active Pending
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