JPWO2022194138A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2022194138A5
JPWO2022194138A5 JP2023557098A JP2023557098A JPWO2022194138A5 JP WO2022194138 A5 JPWO2022194138 A5 JP WO2022194138A5 JP 2023557098 A JP2023557098 A JP 2023557098A JP 2023557098 A JP2023557098 A JP 2023557098A JP WO2022194138 A5 JPWO2022194138 A5 JP WO2022194138A5
Authority
JP
Japan
Prior art keywords
methyl
cinnolin
imidazo
pyridin
ethoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023557098A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024510762A (ja
JP2024510762A5 (https=
JP7833477B2 (ja
Publication date
Priority claimed from PCT/CN2021/081254 external-priority patent/WO2022193166A1/en
Application filed filed Critical
Publication of JP2024510762A publication Critical patent/JP2024510762A/ja
Publication of JP2024510762A5 publication Critical patent/JP2024510762A5/ja
Publication of JPWO2022194138A5 publication Critical patent/JPWO2022194138A5/ja
Application granted granted Critical
Publication of JP7833477B2 publication Critical patent/JP7833477B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023557098A 2021-03-17 2022-03-15 血管拡張性失調症変異(atm)キナーゼの選択的モジュレーターおよびその使用 Active JP7833477B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2021/081254 2021-03-17
PCT/CN2021/081254 WO2022193166A1 (en) 2021-03-17 2021-03-17 Selective modulators of ataxia telangiectasia mutated (atm) kinase and uses thereof
PCT/CN2022/080905 WO2022194138A1 (en) 2021-03-17 2022-03-15 Selective modulators of ataxia telangiectasia mutated (atm) kinase and uses thereof

Publications (4)

Publication Number Publication Date
JP2024510762A JP2024510762A (ja) 2024-03-11
JP2024510762A5 JP2024510762A5 (https=) 2025-03-12
JPWO2022194138A5 true JPWO2022194138A5 (https=) 2025-03-12
JP7833477B2 JP7833477B2 (ja) 2026-03-19

Family

ID=83321678

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023557098A Active JP7833477B2 (ja) 2021-03-17 2022-03-15 血管拡張性失調症変異(atm)キナーゼの選択的モジュレーターおよびその使用

Country Status (8)

Country Link
US (1) US20240207263A1 (https=)
EP (1) EP4308569A4 (https=)
JP (1) JP7833477B2 (https=)
KR (1) KR20230157467A (https=)
CN (1) CN117412972A (https=)
AU (1) AU2021433713A1 (https=)
CA (1) CA3213823A1 (https=)
WO (2) WO2022193166A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021433713A1 (en) * 2021-03-17 2023-09-28 Suzhou Zanrong Pharma Limited Selective modulators of ataxia telangiectasia mutated (atm) kinase and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
BR9707495A (pt) 1996-02-13 1999-07-27 Zeneca Ltd Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente
US6291455B1 (en) 1996-03-05 2001-09-18 Zeneca Limited 4-anilinoquinazoline derivatives
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
BRPI0919932A8 (pt) 2008-10-24 2018-02-06 Novartis Ag Pirrolina-carbóxi-lisina gerada biossinteticamente, bem como processo para preparar método para derivatizar uma proteína
NO2714752T3 (https=) 2014-05-08 2018-04-21
GB201516504D0 (en) * 2015-09-17 2015-11-04 Astrazeneca Ab Imadazo(4,5-c)quinolin-2-one Compounds and their use in treating cancer
GB201519406D0 (en) 2015-11-03 2015-12-16 Astrazeneca Ab Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
WO2019057757A1 (en) * 2017-09-20 2019-03-28 Astrazeneca Ab 1,3-DIHYDROIMIDAZO [4,5-C] CINNOLIN-2-ONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER
JP7436465B2 (ja) * 2018-09-14 2024-02-21 スゾウ、ザンロン、ファーマ、リミテッド 毛細血管拡張性運動失調症変異(ATM)キナーゼの選択的調節物質としての1-イソプロピル-3-メチル-8-(ピリジン-3-イル)-1,3-ジヒドロ-2H-イミダゾ[4,5-c]シンノリン-2-オンおよびその使用
AU2021433713A1 (en) * 2021-03-17 2023-09-28 Suzhou Zanrong Pharma Limited Selective modulators of ataxia telangiectasia mutated (atm) kinase and uses thereof

Similar Documents

Publication Publication Date Title
CN110325533B (zh) Menin-mll相互作用的抑制剂
CN109743875B (zh) Menin-mll相互作用的抑制剂
US20220241261A1 (en) Combinations of inhibitors of irak4 with inhibitors of btk
US10287266B2 (en) Compounds and compositions for inhibiting the activity of SHP2
US11046699B2 (en) Pyrazolo-pyrimidin-amino-cycloalkyl compounds and their therapeutic uses
US10975080B2 (en) Compounds and compositions for inhibiting the activity of SHP2
CN1298328C (zh) 包括应用zd6474和紫杉烷的联合疗法
UA111010C2 (uk) Сполука піразинкарбоксаміду
JPWO2020012334A5 (https=)
RS64234B1 (sr) Pirazolo[1,5-a]pirimidini korisni kao inhibitori atr kinaze za lečenje kancera
JP2017510554A5 (https=)
JP2010512338A5 (https=)
JP2022500428A5 (https=)
JPWO2020057511A5 (https=)
KR102945415B1 (ko) 질소 함유 다환 축합 고리계 화합물, 이의 약학 조성물, 제조 방법 및 용도
JP2018522929A5 (https=)
TW202341982A (zh) Cdk2抑制劑及其用途
JP2024539132A (ja) がんの治療における使用のためのヘテロ環式化合物
JPWO2022194138A5 (https=)
US20250345339A1 (en) Doses and regimens of her2 inhibitors
KR20240155872A (ko) 헤테로사이클릭 화합물 및 사용 방법
EP4301371A1 (en) Substituted 3,6-dihydro-2h-1,3,4-oxadiazin-2-ones for the treatment of sarcoma
CN110997671A (zh) 作为组蛋白甲基转移酶抑制剂的氮杂吲哚化合物
JPWO2020052688A5 (https=)
US20240182468A1 (en) Compounds for the activation of ampk