JPWO2022191313A1 - - Google Patents

Info

Publication number
JPWO2022191313A1
JPWO2022191313A1 JP2023505652A JP2023505652A JPWO2022191313A1 JP WO2022191313 A1 JPWO2022191313 A1 JP WO2022191313A1 JP 2023505652 A JP2023505652 A JP 2023505652A JP 2023505652 A JP2023505652 A JP 2023505652A JP WO2022191313 A1 JPWO2022191313 A1 JP WO2022191313A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023505652A
Other versions
JPWO2022191313A5 (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2022191313A1 publication Critical patent/JPWO2022191313A1/ja
Publication of JPWO2022191313A5 publication Critical patent/JPWO2022191313A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
JP2023505652A 2021-03-12 2022-03-11 Pending JPWO2022191313A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021040164 2021-03-12
PCT/JP2022/010851 WO2022191313A1 (ja) 2021-03-12 2022-03-11 糖鎖及び糖鎖を含む医薬品の製造方法

Publications (2)

Publication Number Publication Date
JPWO2022191313A1 true JPWO2022191313A1 (ja) 2022-09-15
JPWO2022191313A5 JPWO2022191313A5 (ja) 2023-12-07

Family

ID=83228168

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023505652A Pending JPWO2022191313A1 (ja) 2021-03-12 2022-03-11

Country Status (8)

Country Link
EP (1) EP4306546A1 (ja)
JP (1) JPWO2022191313A1 (ja)
KR (1) KR20230157983A (ja)
CN (1) CN116917341A (ja)
BR (1) BR112023017365A2 (ja)
CA (1) CA3212691A1 (ja)
IL (1) IL305816A (ja)
WO (1) WO2022191313A1 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024053574A1 (ja) * 2022-09-09 2024-03-14 第一三共株式会社 新規なオリゴ糖、該オリゴ糖の製造中間体、及びそれらの製造方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
ES2206447T3 (es) 1991-06-14 2004-05-16 Genentech, Inc. Anticuerpo humanizado para heregulina.
EP0727216B1 (en) 1994-07-15 2003-05-28 TAIYO KAGAKU Co., LTD. Medicinal composition containing sialic acid derivative
US6235883B1 (en) 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
ES2552281T3 (es) 2001-05-11 2015-11-26 Ludwig Institute For Cancer Research Ltd. Proteínas de unión específica y usos de las mismas
PT1585966E (pt) 2002-07-15 2012-02-20 Hoffmann La Roche Tratamento de cancro com o anticorpo anti-erbb2 rhumab 2c4
JP5356648B2 (ja) 2003-02-20 2013-12-04 シアトル ジェネティックス， インコーポレイテッド 抗ｃｄ７０抗体−医薬結合体、ならびに癌および免疫障害の処置のためのそれらの使用
EP1934261B1 (en) 2005-09-26 2014-10-29 Medarex, L.L.C. Human monoclonal antibodies to cd70
JP2009155353A (ja) * 2006-03-30 2009-07-16 Yokohama City Univ 糖鎖化合物の製造方法
PL2199390T3 (pl) 2007-08-30 2017-06-30 Daiichi Sankyo Company, Limited Przeciwciało anty-epha2
WO2011027868A1 (ja) 2009-09-03 2011-03-10 公益財団法人野口研究所 １１糖シアリルオリゴ糖ペプチドの製造方法
US10851174B2 (en) * 2011-03-03 2020-12-01 University Of Maryland, Baltimore Core fucosylated glycopeptides and glycoproteins: chemoenzymatic synthesis and uses thereof
WO2012135049A1 (en) * 2011-03-25 2012-10-04 University Of Georgia Research Foundation, Inc. Compounds and methods for chemical and chemo-enzymatic synthesis of complex glycans
NZ746440A (en) 2012-10-11 2019-11-29 Daiichi Sankyo Co Ltd Glycinamide derivatives and production methods thereof
TW201442721A (zh) * 2013-01-23 2014-11-16 Daiichi Sankyo Co Ltd 糖鏈修飾心房利尿鈉肽
TW201534613A (zh) 2013-06-28 2015-09-16 Daiichi Sankyo Co Ltd 寡糖胜肽之純化方法
WO2015080603A1 (en) * 2013-11-28 2015-06-04 Antony John Fairbanks Glycoproteins
AU2014371934B2 (en) 2013-12-25 2020-01-23 Daiichi Sankyo Company, Limited Anti-TROP2 antibody-drug conjugate
US11559581B2 (en) 2015-01-09 2023-01-24 Oxford University Innovation Limited Antibody conjugates and methods of making the antibody conjugates
WO2017110984A1 (ja) 2015-12-25 2017-06-29 第一三共株式会社 限外ろ過膜を用いたオリゴ糖ペプチドの精製法
EP3480211A4 (en) 2016-07-01 2019-12-25 Daiichi Sankyo Company, Limited HANP FC CONTAINING MOLECULAR CONJUGATE
JP6342968B2 (ja) * 2016-07-25 2018-06-13 株式会社伏見製薬所 糖誘導体の製造方法及び新規糖誘導体
TWI794230B (zh) 2017-05-15 2023-03-01 日商第一三共股份有限公司 抗ｃｄｈ６抗體及抗ｃｄｈ６抗體-藥物結合物、以及其製造方法
CN111164208B (zh) 2017-09-29 2023-08-04 第一三共株式会社 抗体－吡咯并苯并二氮杂卓衍生物偶联物
BR112021003472A2 (pt) 2018-09-06 2021-05-18 Daiichi Sankyo Company, Limited derivado de dinucleotídeo cíclico e conjugado de anticorpo-fármaco do mesmo

Also Published As

Publication number Publication date
CN116917341A (zh) 2023-10-20
CA3212691A1 (en) 2022-09-15
WO2022191313A1 (ja) 2022-09-15
EP4306546A1 (en) 2024-01-17
KR20230157983A (ko) 2023-11-17
IL305816A (en) 2023-11-01
BR112023017365A2 (pt) 2023-10-03

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