JPWO2022092141A5 - - Google Patents
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- Publication number
- JPWO2022092141A5 JPWO2022092141A5 JP2022559192A JP2022559192A JPWO2022092141A5 JP WO2022092141 A5 JPWO2022092141 A5 JP WO2022092141A5 JP 2022559192 A JP2022559192 A JP 2022559192A JP 2022559192 A JP2022559192 A JP 2022559192A JP WO2022092141 A5 JPWO2022092141 A5 JP WO2022092141A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- compound
- pharmaceutically acceptable
- aromatic heterocyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 31
- 150000003839 salts Chemical class 0.000 claims 20
- 125000006615 aromatic heterocyclic group Chemical group 0.000 claims 16
- 125000000217 alkyl group Chemical group 0.000 claims 11
- 125000003118 aryl group Chemical group 0.000 claims 10
- 125000002837 carbocyclic group Chemical group 0.000 claims 10
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 9
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 125000004432 carbon atom Chemical group C* 0.000 claims 4
- 229910052736 halogen Inorganic materials 0.000 claims 4
- 150000002367 halogens Chemical class 0.000 claims 4
- 125000003342 alkenyl group Chemical group 0.000 claims 3
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 3
- -1 amino, hydroxy Chemical group 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 125000004390 alkyl sulfonyl group Chemical group 0.000 claims 1
- 125000002947 alkylene group Chemical group 0.000 claims 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 claims 1
- 125000005740 oxycarbonyl group Chemical group [*:1]OC([*:2])=O 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020180856 | 2020-10-28 | ||
| JP2020180856 | 2020-10-28 | ||
| PCT/JP2021/039623 WO2022092141A1 (ja) | 2020-10-28 | 2021-10-27 | 抗ウイルス活性を有するアミド誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2022092141A1 JPWO2022092141A1 (https=) | 2022-05-05 |
| JPWO2022092141A5 true JPWO2022092141A5 (https=) | 2023-07-13 |
| JP7358657B2 JP7358657B2 (ja) | 2023-10-10 |
Family
ID=81382618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022559192A Active JP7358657B2 (ja) | 2020-10-28 | 2021-10-27 | 抗ウイルス活性を有するアミド誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US12528790B2 (https=) |
| EP (1) | EP4238960A4 (https=) |
| JP (1) | JP7358657B2 (https=) |
| KR (1) | KR102734880B1 (https=) |
| CN (3) | CN116528850B (https=) |
| AU (1) | AU2021368444B2 (https=) |
| CA (1) | CA3200111C (https=) |
| CO (1) | CO2023005496A2 (https=) |
| IL (1) | IL302458B2 (https=) |
| MX (1) | MX2023004779A (https=) |
| TW (1) | TWI839652B (https=) |
| WO (1) | WO2022092141A1 (https=) |
| ZA (1) | ZA202305385B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116528850B (zh) * | 2020-10-28 | 2025-08-22 | 盐野义制药株式会社 | 具有抗病毒活性的酰胺衍生物 |
| CN119060016B (zh) * | 2023-12-14 | 2025-07-29 | 杭州师范大学 | 具有rsv抑制活性的酰胺衍生物及其制备方法和应用 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7087597B1 (en) * | 1999-10-12 | 2006-08-08 | Takeda Pharmaceutical Company Limited | Pyrimidine 5-carboxamide compounds, process for producing the same and use thereof |
| SE0302232D0 (sv) * | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
| US20070238718A1 (en) * | 2006-04-06 | 2007-10-11 | Matthias Grauert | Thiazolyl-dihydro-indazole |
| TWI515187B (zh) | 2010-12-16 | 2016-01-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之吲哚類 |
| EP2691375B1 (en) * | 2011-03-31 | 2016-03-16 | Bayer Intellectual Property GmbH | Substituted benzimidazoles as mps-1 kinase inhibitors |
| CN106986869A (zh) * | 2012-04-17 | 2017-07-28 | 吉利德科学公司 | 用于抗病毒治疗的化合物和方法 |
| AU2013305759C1 (en) * | 2012-08-23 | 2018-01-18 | Janssen Biopharma, Inc. | Compounds for the treatment of paramoxyvirus viral infections |
| WO2014070976A1 (en) | 2012-11-03 | 2014-05-08 | Boehringer Ingelheim International Gmbh | Inhibitors of cytomegalovirus |
| EP2997028A1 (en) * | 2013-05-14 | 2016-03-23 | F.Hoffmann-La Roche Ag | Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection |
| NZ716822A (en) | 2013-08-21 | 2017-10-27 | Alios Biopharma Inc | Antiviral compounds |
| MA41614A (fr) | 2015-02-25 | 2018-01-02 | Alios Biopharma Inc | Composés antiviraux |
| JP2018076234A (ja) * | 2015-03-16 | 2018-05-17 | 大正製薬株式会社 | ピラゾロ［１，５−ａ］ピリミジン化合物 |
| JO3637B1 (ar) | 2015-04-28 | 2020-08-27 | Janssen Sciences Ireland Uc | مركبات بيرازولو- وترايازولو- بيريميدين مضادة للفيروسات rsv |
| US10906899B2 (en) | 2016-05-10 | 2021-02-02 | Georgia State University Research Foundation, Inc. | Bicyclic fused pyrazole derivatives for the treatment of RSV |
| TW201932470A (zh) | 2017-11-29 | 2019-08-16 | 愛爾蘭商健生科學愛爾蘭無限公司 | 具有抗ｒｓｖ活性之吡唑并嘧啶 |
| TW201936193A (zh) | 2017-12-05 | 2019-09-16 | 愛爾蘭商健生科學愛爾蘭無限公司 | 使用組合產品治療ｒｓｖ |
| CN111670189A (zh) | 2018-01-31 | 2020-09-15 | 爱尔兰詹森科学公司 | 对rsv具有活性的环烷基取代的吡唑并嘧啶 |
| MA52348A (fr) | 2018-04-23 | 2021-03-03 | Janssen Sciences Ireland Unlimited Co | Composés hétéroaromatiques ayant une activité contre vrs |
| EA202191482A1 (ru) | 2018-11-26 | 2021-12-14 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Другие гетероароматические соединения, обладающие активностью против rsv |
| EP3972964A1 (en) | 2019-05-23 | 2022-03-30 | Janssen Sciences Ireland Unlimited Company | Other heteroaromatic compounds having activity against rsv |
| AU2020357452B2 (en) | 2019-10-04 | 2026-01-29 | Enanta Pharmaceuticals, Inc | Antiviral heterocyclic compounds |
| UY39032A (es) | 2020-01-24 | 2021-07-30 | Enanta Pharm Inc | Compuestos heterocíclicos como agentes antivirales |
| WO2021198981A1 (en) | 2020-04-01 | 2021-10-07 | Janssen Biopharma, Inc. | Antiviral compounds and uses thereof |
| JP2023522091A (ja) | 2020-04-21 | 2023-05-26 | ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー | Ｒｓｖ阻害性の３置換キノリン及びシンノリン誘導体 |
| US11945824B2 (en) | 2020-10-19 | 2024-04-02 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as anti-viral agents |
| CN116528850B (zh) * | 2020-10-28 | 2025-08-22 | 盐野义制药株式会社 | 具有抗病毒活性的酰胺衍生物 |
| IL305189A (en) | 2021-02-26 | 2023-10-01 | Enanta Pharm Inc | Heterocyclic antiviral compounds |
| WO2022211812A1 (en) | 2021-04-01 | 2022-10-06 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
-
2021
- 2021-10-27 CN CN202180073587.7A patent/CN116528850B/zh active Active
- 2021-10-27 US US18/034,318 patent/US12528790B2/en active Active
- 2021-10-27 WO PCT/JP2021/039623 patent/WO2022092141A1/ja not_active Ceased
- 2021-10-27 TW TW110139880A patent/TWI839652B/zh active
- 2021-10-27 EP EP21886259.7A patent/EP4238960A4/en active Pending
- 2021-10-27 CN CN202511115140.8A patent/CN121021491A/zh active Pending
- 2021-10-27 JP JP2022559192A patent/JP7358657B2/ja active Active
- 2021-10-27 KR KR1020237016655A patent/KR102734880B1/ko active Active
- 2021-10-27 MX MX2023004779A patent/MX2023004779A/es unknown
- 2021-10-27 AU AU2021368444A patent/AU2021368444B2/en active Active
- 2021-10-27 CA CA3200111A patent/CA3200111C/en active Active
- 2021-10-27 IL IL302458A patent/IL302458B2/en unknown
- 2021-10-27 CN CN202311304219.6A patent/CN117362306B/zh active Active
-
2023
- 2023-04-28 CO CONC2023/0005496A patent/CO2023005496A2/es unknown
- 2023-05-17 ZA ZA2023/05385A patent/ZA202305385B/en unknown
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