JPWO2021207526A5 - - Google Patents
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- Publication number
- JPWO2021207526A5 JPWO2021207526A5 JP2022561637A JP2022561637A JPWO2021207526A5 JP WO2021207526 A5 JPWO2021207526 A5 JP WO2021207526A5 JP 2022561637 A JP2022561637 A JP 2022561637A JP 2022561637 A JP2022561637 A JP 2022561637A JP WO2021207526 A5 JPWO2021207526 A5 JP WO2021207526A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- chimeric polypeptide
- domain
- protein
- ligand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063007807P | 2020-04-09 | 2020-04-09 | |
| US63/007,807 | 2020-04-09 | ||
| US202163165588P | 2021-03-24 | 2021-03-24 | |
| US63/165,588 | 2021-03-24 | ||
| PCT/US2021/026430 WO2021207526A1 (en) | 2020-04-09 | 2021-04-08 | Humanized notch receptors with hinge domain |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023521147A JP2023521147A (ja) | 2023-05-23 |
| JPWO2021207526A5 true JPWO2021207526A5 (https=) | 2024-04-17 |
| JP2023521147A5 JP2023521147A5 (https=) | 2024-04-17 |
Family
ID=78023652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022561637A Pending JP2023521147A (ja) | 2020-04-09 | 2021-04-08 | ヒンジドメインを有するヒト化ｎｏｔｃｈ受容体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230183709A1 (https=) |
| EP (1) | EP4132659A4 (https=) |
| JP (1) | JP2023521147A (https=) |
| KR (1) | KR20220166833A (https=) |
| CN (1) | CN115666726A (https=) |
| AU (1) | AU2021251212A1 (https=) |
| BR (1) | BR112022020415A2 (https=) |
| CA (1) | CA3179954A1 (https=) |
| IL (1) | IL297092A (https=) |
| WO (1) | WO2021207526A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2022366987A1 (en) | 2021-10-14 | 2024-05-16 | Arsenal Biosciences, Inc. | Immune cells having co-expressed shrnas and logic gate systems |
| KR20250158048A (ko) | 2023-03-03 | 2025-11-05 | 아스널 바이오사이언시스, 인크. | Psma 및 ca9을 표적으로 하는 시스템 |
| CN121038806A (zh) * | 2023-04-25 | 2025-11-28 | 阿森纳生物科学公司 | 用于转录调控的新颖受体 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6333167B1 (en) * | 2000-03-10 | 2001-12-25 | American Home Products Corp. | Methods and reagents for identifying inhibitors of proteolysis of membrane-associated proteins |
| CN103502466A (zh) * | 2010-09-07 | 2014-01-08 | 斯隆－凯特林纪念癌症中心 | 用于γ-分泌酶测定的方法和组合物 |
| EP2970426B1 (en) * | 2013-03-15 | 2019-08-28 | Michael C. Milone | Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy |
| WO2016138034A1 (en) * | 2015-02-24 | 2016-09-01 | The Regents Of The University Of California | Binding-triggered transcriptional switches and methods of use thereof |
| JP7500195B2 (ja) * | 2016-08-23 | 2024-06-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | タンパク質分解により切断可能なキメラポリペプチド及びそれらの使用方法 |
| US11325957B2 (en) * | 2017-06-19 | 2022-05-10 | Cell Design Labs, Inc. | Methods and compositions for reducing the immunogenicity of chimeric notch receptors |
| WO2019217913A1 (en) * | 2018-05-10 | 2019-11-14 | Sensei Biotherapeutics, Inc. | Aspartate beta-hydroxylase chimeric antigen receptors and uses thereof |
| US20220340637A1 (en) * | 2019-09-24 | 2022-10-27 | The Regents Of The University Of California | Notch receptors with minimal linker |
| WO2021061872A1 (en) * | 2019-09-24 | 2021-04-01 | The Regents Of The University Of California | Novel receptors having a heterologous stop transfer sequence for ligand-dependent transcriptional regulation |
| CN114761084B (zh) * | 2019-09-24 | 2023-10-27 | 加利福尼亚大学董事会 | 具有铰链结构域的Notch受体 |
| EP4034254A4 (en) * | 2019-09-24 | 2023-11-01 | The Regents of the University of California | RECEPTORS WITH HETEROLOGUE TRANSMEMBRANE DOMAIN |
| WO2021061791A1 (en) * | 2019-09-24 | 2021-04-01 | The Regents Of The University Of California | Notch receptors with zinc finger-containing transcriptional effector |
-
2021
- 2021-04-08 US US17/995,751 patent/US20230183709A1/en active Pending
- 2021-04-08 WO PCT/US2021/026430 patent/WO2021207526A1/en not_active Ceased
- 2021-04-08 JP JP2022561637A patent/JP2023521147A/ja active Pending
- 2021-04-08 KR KR1020227038985A patent/KR20220166833A/ko active Pending
- 2021-04-08 EP EP21785532.9A patent/EP4132659A4/en active Pending
- 2021-04-08 IL IL297092A patent/IL297092A/en unknown
- 2021-04-08 CN CN202180039079.7A patent/CN115666726A/zh active Pending
- 2021-04-08 CA CA3179954A patent/CA3179954A1/en active Pending
- 2021-04-08 BR BR112022020415A patent/BR112022020415A2/pt unknown
- 2021-04-08 AU AU2021251212A patent/AU2021251212A1/en active Pending
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